TY  - JOUR
AU  - Vidović, Srđan
AU  - Stojkovska, Jasmina
AU  - Stevanović, Milan
AU  - Balanč, Bojana
AU  - Vukašinović-Sekulić, Maja
AU  - Marinković, Aleksandar
AU  - Obradović, Bojana
PY  - 2022
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/5105
AB  - In this work, nanocomposite fibres and microfibres based on alginate and poly(vinyl alcohol) (PVA) with silver nanoparticles (AgNPs) were produced and characterized for potential application as antibacterial wound dressings. PVA/Ag/Na-alginate colloid solution was used for the preparation of the fibres by a simple extrusion technique followed by freezing-thawing cycles. UV-Visible spectroscopy confirmed successful preservation of AgNPs in fibres while Fourier transform infrared spectroscopy has shown a balanced combined effect on the Ca-alginate spatial arrangement with the addition of both AgNPs and PVA. The presence of PVA in fibres induced an increase in the swelling degree as compared with that of Ag/Ca-alginate fibres (approx. 28 versus approx. 14). Still, the initially produced PVA/Ca-alginate fibres were mechanically weaker than Ca-alginate fibres, but after drying and rehydration exhibited better mechanical properties. Also, the obtained fibres released AgNPs and/or silver ions at the concentration of approximately 2.6 μg cm -3 leading to bacteriostatic effects against Staphylococcus aureus and Escherichia coli. These results are relevant for practical utilization of the fibres, which could be stored and applied in the dry form with preserved mechanical stability, sorption capacity and antibacterial activity.
PB  - Royal Society Publishing
T2  - Royal Society Open Science
T1  - Effects of poly(vinyl alcohol) blending with Ag/alginate solutions to form nanocomposite fibres for potential use as antibacterial wound dressings
IS  - 3
SP  - 211517
VL  - 9
DO  - 10.1098/rsos.211517
ER  - 

@article{
author = "Vidović, Srđan and Stojkovska, Jasmina and Stevanović, Milan and Balanč, Bojana and Vukašinović-Sekulić, Maja and Marinković, Aleksandar and Obradović, Bojana",
year = "2022",
abstract = "In this work, nanocomposite fibres and microfibres based on alginate and poly(vinyl alcohol) (PVA) with silver nanoparticles (AgNPs) were produced and characterized for potential application as antibacterial wound dressings. PVA/Ag/Na-alginate colloid solution was used for the preparation of the fibres by a simple extrusion technique followed by freezing-thawing cycles. UV-Visible spectroscopy confirmed successful preservation of AgNPs in fibres while Fourier transform infrared spectroscopy has shown a balanced combined effect on the Ca-alginate spatial arrangement with the addition of both AgNPs and PVA. The presence of PVA in fibres induced an increase in the swelling degree as compared with that of Ag/Ca-alginate fibres (approx. 28 versus approx. 14). Still, the initially produced PVA/Ca-alginate fibres were mechanically weaker than Ca-alginate fibres, but after drying and rehydration exhibited better mechanical properties. Also, the obtained fibres released AgNPs and/or silver ions at the concentration of approximately 2.6 μg cm -3 leading to bacteriostatic effects against Staphylococcus aureus and Escherichia coli. These results are relevant for practical utilization of the fibres, which could be stored and applied in the dry form with preserved mechanical stability, sorption capacity and antibacterial activity.",
publisher = "Royal Society Publishing",
journal = "Royal Society Open Science",
title = "Effects of poly(vinyl alcohol) blending with Ag/alginate solutions to form nanocomposite fibres for potential use as antibacterial wound dressings",
number = "3",
pages = "211517",
volume = "9",
doi = "10.1098/rsos.211517"
}

Vidović, S., Stojkovska, J., Stevanović, M., Balanč, B., Vukašinović-Sekulić, M., Marinković, A.,& Obradović, B.. (2022). Effects of poly(vinyl alcohol) blending with Ag/alginate solutions to form nanocomposite fibres for potential use as antibacterial wound dressings. in Royal Society Open Science
Royal Society Publishing., 9(3), 211517.
https://doi.org/10.1098/rsos.211517

Vidović S, Stojkovska J, Stevanović M, Balanč B, Vukašinović-Sekulić M, Marinković A, Obradović B. Effects of poly(vinyl alcohol) blending with Ag/alginate solutions to form nanocomposite fibres for potential use as antibacterial wound dressings. in Royal Society Open Science. 2022;9(3):211517.
doi:10.1098/rsos.211517 .

Vidović, Srđan, Stojkovska, Jasmina, Stevanović, Milan, Balanč, Bojana, Vukašinović-Sekulić, Maja, Marinković, Aleksandar, Obradović, Bojana, "Effects of poly(vinyl alcohol) blending with Ag/alginate solutions to form nanocomposite fibres for potential use as antibacterial wound dressings" in Royal Society Open Science, 9, no. 3 (2022):211517,
https://doi.org/10.1098/rsos.211517 . .