@conference{
author = "Korica, Matea and Fras Zemljič, Lidija and Bračić, Matej and Kargl, Rupert and Kostić, Mirjana",
year = "2018",
abstract = "In this work, regenerated cellulose (RC) films was coated with
TEMPO oxidized cellulose nanofibrils (TOCN) and chitosan (CS) by means of
subsequent spin-coated deposition. The bioactivity of coatings was
achieved by addition of chitosan. The chitosan was either mixed
with the TOCN (TOCN+CS) and deposited on the RC film by spin-coating or
deposited on the RC/TOCN bilayer film by pumping its aqueous solution at
pH 5.5 over the surface of the film. The pH dependant charging behaviour
of the TOCN, TOCN+CS, and CS were evaluated by pH-potentiometric
titrations. The protein-repellent properties of investigated coatings were
evaluated in situ using a continuous flow of bovine serum albumin (BSA) by
means of
quartz crystal microbalance with dissipation (QCM-D). Antioxidative
activity of TOCN, CS and their amphoteric mixture was determined using the
2,2′-azino-bis(3-ethyl benzothiazoline-6-sulfonic acid) radical scavenging
assay. Coating with improved protein repellent properties was obtained
using TOCN+CS amphoteric mixture, but on the other hand TOCN+CS amphoteric
mixture showed weaker antioxidative properties in comparison to TOCN and
CS., U ovom radu, filmovi od regenerisane celuloze (RC) su naslojeni
sa TEMPO oksidisanim celuloznim nanofibrilima (TOCN) i hitozanom (CS)
metodom rotirajućeg diska. Bioaktivnost prevlaka postignuta je dodavanjem
hitozana. Hitozan je ili pomešan sa TOCN (TOCN+CS) i naslojen na RC film
tehnikom rotirajućeg diska ili nanesen na RC/TOCN dvoslojni film
propumpavanjem njegovog vodenog rastvora, pH vrednosti 5,5, preko površine
filma.
Naelektrisanje TOCN, TOCN+CS i CS u zavisnosti od pH je okarakterisano
pH-potenciometrijskim titracijama. Protein-odbijajuća svojstva ispitivanih
prevlaka određena su in situ, u kontinualnom toku goveđeg serumskog
albumina (BSA) primenom kvarc-kristal mikrovage sa praćenjem disipacije
(QCM-D). Antioksidativna svojstva TOCN, CS i TOCN+CS amfoterne mešavine su
određena metodom inhibicije radikala
2,2′-azino-bis(3-etil benzotiazolin-6-sulfonske kiseline). Prevlaka sa
poboljšanim protein-odbijajućim svojstvima
je dobijena upotrebom TOCN+CS amfoterne mešavine, ali sa druge strane
TOCN+CS amfoterna mešavina je pokazala slabija antioksidativna svojstva u
poređenju sa TOCN i CS.",
publisher = "Beograd : Serbian Chemical Society",
journal = "Proceedings / 55th Meeting of the Serbian Chemical Society, Novi Sad, Serbia, June 8-9, 2018",
title = "Protein-repellent and antioxidative properties of bioactive coatings based on TEMPO oxidized cellulose nanofibrils and chitosan, Protein-odbijajuća i antioksidativna svojstva bioaktivnih
prevlaka na bazi TEMPO oksidisanih celuloznih nanofibrila i hitozana",
pages = "76-66",
url = "https://hdl.handle.net/21.15107/rcub_technorep_6831"
}