TY  - JOUR
AU  - Popescu, A. C.
AU  - Sima, F.
AU  - Duta, L.
AU  - Popescu, A. C.
AU  - Mihailescu, Ion N.
AU  - Capitanu, D.
AU  - Mustata, R.
AU  - Sima, L. E.
AU  - Petrescu, S. M.
AU  - Janaćković, Đorđe
PY  - 2009
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/1483
AB  - We report on the synthesis by pulsed laser deposition with a KrF* excimer laser source (lambda = 248 nm, tau = 25 ns) of bioglass thin films of 6P57 and 6P61 types. Physiology, viability, and proliferation of human osteoblast cells were determined by quantitative in vitro tests performed by flow cytometry on primary osteoblasts cultured on pulsed laser deposited bioglasses. Both types of glass films proved to be appropriate mediums for cell survival and proliferation. In a parallel investigation, cell morphology and adhesion to the surface was studied by fluorescence microscopy and scanning electron microscopy. Strong bonds between the materials and cells were found in both cases, as osteoblast pseudopodes penetrated deep into the material. According to our observations, the 6P57 glass films were superior with respect to viability and proliferation performances.
PB  - Elsevier, Amsterdam
T2  - Applied Surface Science
T1  - Biocompatible and bioactive nanostructured glass coatings synthesized by pulsed laser deposition: In vitro biological tests
EP  - 5490
IS  - 10
SP  - 5486
VL  - 255
DO  - 10.1016/j.apsusc.2008.10.031
ER  - 

@article{
author = "Popescu, A. C. and Sima, F. and Duta, L. and Popescu, A. C. and Mihailescu, Ion N. and Capitanu, D. and Mustata, R. and Sima, L. E. and Petrescu, S. M. and Janaćković, Đorđe",
year = "2009",
abstract = "We report on the synthesis by pulsed laser deposition with a KrF* excimer laser source (lambda = 248 nm, tau = 25 ns) of bioglass thin films of 6P57 and 6P61 types. Physiology, viability, and proliferation of human osteoblast cells were determined by quantitative in vitro tests performed by flow cytometry on primary osteoblasts cultured on pulsed laser deposited bioglasses. Both types of glass films proved to be appropriate mediums for cell survival and proliferation. In a parallel investigation, cell morphology and adhesion to the surface was studied by fluorescence microscopy and scanning electron microscopy. Strong bonds between the materials and cells were found in both cases, as osteoblast pseudopodes penetrated deep into the material. According to our observations, the 6P57 glass films were superior with respect to viability and proliferation performances.",
publisher = "Elsevier, Amsterdam",
journal = "Applied Surface Science",
title = "Biocompatible and bioactive nanostructured glass coatings synthesized by pulsed laser deposition: In vitro biological tests",
pages = "5490-5486",
number = "10",
volume = "255",
doi = "10.1016/j.apsusc.2008.10.031"
}

Popescu, A. C., Sima, F., Duta, L., Popescu, A. C., Mihailescu, I. N., Capitanu, D., Mustata, R., Sima, L. E., Petrescu, S. M.,& Janaćković, Đ.. (2009). Biocompatible and bioactive nanostructured glass coatings synthesized by pulsed laser deposition: In vitro biological tests. in Applied Surface Science
Elsevier, Amsterdam., 255(10), 5486-5490.
https://doi.org/10.1016/j.apsusc.2008.10.031

Popescu AC, Sima F, Duta L, Popescu AC, Mihailescu IN, Capitanu D, Mustata R, Sima LE, Petrescu SM, Janaćković Đ. Biocompatible and bioactive nanostructured glass coatings synthesized by pulsed laser deposition: In vitro biological tests. in Applied Surface Science. 2009;255(10):5486-5490.
doi:10.1016/j.apsusc.2008.10.031 .

Popescu, A. C., Sima, F., Duta, L., Popescu, A. C., Mihailescu, Ion N., Capitanu, D., Mustata, R., Sima, L. E., Petrescu, S. M., Janaćković, Đorđe, "Biocompatible and bioactive nanostructured glass coatings synthesized by pulsed laser deposition: In vitro biological tests" in Applied Surface Science, 255, no. 10 (2009):5486-5490,
https://doi.org/10.1016/j.apsusc.2008.10.031 . .

TY  - JOUR
AU  - Floroian, L.
AU  - Savu, B.
AU  - Stanciu, G.
AU  - Popescu, A. C.
AU  - Sima, F.
AU  - Mihailescu, Ion N.
AU  - Mustata, R.
AU  - Sima, L. E.
AU  - Petrescu, M.
AU  - Tanasković, Dušanka
AU  - Janaćković, Đorđe
PY  - 2008
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/1230
AB  - We report the synthesis by pulsed laser deposition of thin structures of two bioactive glasses belonging to the SiO2-Na2O-K2O-CaO-MgO-P2O5 system, on medical grade Ti substrates. We evaluated their biocompatibility after immersion in simulated body fluids and by performing cells adhesion tests. The Films were characterized by confocal scanning laser microscopy and Fourier transform infrared spectrometry, before and after 30 and 46 days immersion in fluids. Our studies demonstrated that deposited coatings were degraded in simulated fluids. A new apatite layer was synthesized by ions changing with the fluid during the decomposition of bioglasses. We investigated after immersion in fluids cells adhesion and the cytoskelet organization of synthesized structures, by fluorescence microscopy. A good adhesion to bioglass coatings was evidenced.
PB  - Elsevier, Amsterdam
T2  - Applied Surface Science
T1  - Nanostructured bioglass thin films synthesized by pulsed laser deposition: CSLM, FTIR investigations and in vitro biotests
EP  - 3062
IS  - 5
SP  - 3056
VL  - 255
DO  - 10.1016/j.apsusc.2008.08.105
ER  - 

@article{
author = "Floroian, L. and Savu, B. and Stanciu, G. and Popescu, A. C. and Sima, F. and Mihailescu, Ion N. and Mustata, R. and Sima, L. E. and Petrescu, M. and Tanasković, Dušanka and Janaćković, Đorđe",
year = "2008",
abstract = "We report the synthesis by pulsed laser deposition of thin structures of two bioactive glasses belonging to the SiO2-Na2O-K2O-CaO-MgO-P2O5 system, on medical grade Ti substrates. We evaluated their biocompatibility after immersion in simulated body fluids and by performing cells adhesion tests. The Films were characterized by confocal scanning laser microscopy and Fourier transform infrared spectrometry, before and after 30 and 46 days immersion in fluids. Our studies demonstrated that deposited coatings were degraded in simulated fluids. A new apatite layer was synthesized by ions changing with the fluid during the decomposition of bioglasses. We investigated after immersion in fluids cells adhesion and the cytoskelet organization of synthesized structures, by fluorescence microscopy. A good adhesion to bioglass coatings was evidenced.",
publisher = "Elsevier, Amsterdam",
journal = "Applied Surface Science",
title = "Nanostructured bioglass thin films synthesized by pulsed laser deposition: CSLM, FTIR investigations and in vitro biotests",
pages = "3062-3056",
number = "5",
volume = "255",
doi = "10.1016/j.apsusc.2008.08.105"
}

Floroian, L., Savu, B., Stanciu, G., Popescu, A. C., Sima, F., Mihailescu, I. N., Mustata, R., Sima, L. E., Petrescu, M., Tanasković, D.,& Janaćković, Đ.. (2008). Nanostructured bioglass thin films synthesized by pulsed laser deposition: CSLM, FTIR investigations and in vitro biotests. in Applied Surface Science
Elsevier, Amsterdam., 255(5), 3056-3062.
https://doi.org/10.1016/j.apsusc.2008.08.105

Floroian L, Savu B, Stanciu G, Popescu AC, Sima F, Mihailescu IN, Mustata R, Sima LE, Petrescu M, Tanasković D, Janaćković Đ. Nanostructured bioglass thin films synthesized by pulsed laser deposition: CSLM, FTIR investigations and in vitro biotests. in Applied Surface Science. 2008;255(5):3056-3062.
doi:10.1016/j.apsusc.2008.08.105 .

Floroian, L., Savu, B., Stanciu, G., Popescu, A. C., Sima, F., Mihailescu, Ion N., Mustata, R., Sima, L. E., Petrescu, M., Tanasković, Dušanka, Janaćković, Đorđe, "Nanostructured bioglass thin films synthesized by pulsed laser deposition: CSLM, FTIR investigations and in vitro biotests" in Applied Surface Science, 255, no. 5 (2008):3056-3062,
https://doi.org/10.1016/j.apsusc.2008.08.105 . .

TY  - JOUR
AU  - Floroian, L.
AU  - Savu, B.
AU  - Sima, F.
AU  - Mihailescu, Ion N.
AU  - Tanasković, Dušanka
AU  - Janaćković, Đorđe
PY  - 2007
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/1177
AB  - We report the successful pulsed laser deposition on medical grade Ti substrates of thin films made of two bioactive glasses in the SiO2 - Na2O- K2O - CaO - MgO - P2O5 system. The films were topographically and chemically characterized by confocal scanning laser microscopy and Fourier transform infrared spectrophotometry. Our studies proved that chemical composition was similar in the base material and deposited films. The latter were rather uniform and rough enough to favor enhanced biocompatibility.
PB  - Inst Materials Physics, Bucharest
T2  - Digest Journal of Nanomaterials and Biostructures
T1  - Synthesis and characterization of bioglass thin films
EP  - 291
IS  - 3
SP  - 285
VL  - 2
UR  - https://hdl.handle.net/21.15107/rcub_technorep_1177
ER  - 

@article{
author = "Floroian, L. and Savu, B. and Sima, F. and Mihailescu, Ion N. and Tanasković, Dušanka and Janaćković, Đorđe",
year = "2007",
abstract = "We report the successful pulsed laser deposition on medical grade Ti substrates of thin films made of two bioactive glasses in the SiO2 - Na2O- K2O - CaO - MgO - P2O5 system. The films were topographically and chemically characterized by confocal scanning laser microscopy and Fourier transform infrared spectrophotometry. Our studies proved that chemical composition was similar in the base material and deposited films. The latter were rather uniform and rough enough to favor enhanced biocompatibility.",
publisher = "Inst Materials Physics, Bucharest",
journal = "Digest Journal of Nanomaterials and Biostructures",
title = "Synthesis and characterization of bioglass thin films",
pages = "291-285",
number = "3",
volume = "2",
url = "https://hdl.handle.net/21.15107/rcub_technorep_1177"
}

Floroian, L., Savu, B., Sima, F., Mihailescu, I. N., Tanasković, D.,& Janaćković, Đ.. (2007). Synthesis and characterization of bioglass thin films. in Digest Journal of Nanomaterials and Biostructures
Inst Materials Physics, Bucharest., 2(3), 285-291.
https://hdl.handle.net/21.15107/rcub_technorep_1177

Floroian L, Savu B, Sima F, Mihailescu IN, Tanasković D, Janaćković Đ. Synthesis and characterization of bioglass thin films. in Digest Journal of Nanomaterials and Biostructures. 2007;2(3):285-291.
https://hdl.handle.net/21.15107/rcub_technorep_1177 .

Floroian, L., Savu, B., Sima, F., Mihailescu, Ion N., Tanasković, Dušanka, Janaćković, Đorđe, "Synthesis and characterization of bioglass thin films" in Digest Journal of Nanomaterials and Biostructures, 2, no. 3 (2007):285-291,
https://hdl.handle.net/21.15107/rcub_technorep_1177 .