TY  - JOUR
AU  - Radisavljević, Anđela
AU  - Stojanović, Dušica B.
AU  - Petrović, Miloš
AU  - Radojević, Vesna
AU  - Uskoković, Petar
AU  - Rajilić-Stojanović, Mirjana
PY  - 2023
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/5295
AB  - In this study, polycaprolactone (PCL), as a biocompatible polymer was functionalized by addition of medicinal plant extract- Achillea millefolium L. (yarrow). Nanofiber mats were fabricated from PCL solutions containing dry yarrow extract in four concentrations (5%, 10%, 15%, and 20% relative to the weight of the polymer) by using blend electrospinning method. The nanofibers were characterized for their biological, mechanical and drug release behavior. In vitro release of yarrow polyphenols from the electrospun PCL nanofibers over a period of 5 days showed the release of up to 98% of the total loaded polyphenols. The released polyphenols retained its antioxidant activity, which was determined by DPPH assay. Electrospun PCL/yarrow nanofiber mats exhibited the antibacterial effect against Staphylococcus aureus, but had no effect on the growth of Pseudomonas aeruginosa. All PCL/yarrow nanofiber mats had improved mechanical properties compared to the neat PCL nanofibers, as evident by an increase in Young's modulus of elasticity (up to 5.7 times), the tensile strength (up to 5.5 times), and the strain at break (up to 1.45 times). Based on our results, yarrow-loaded PCL nanofiber mats appeared to be multi-functional biomaterials suitable for the production of catheter-coating materials, patches, or gauzes with antibacterial and antioxidant properties.
PB  - John Wiley and Sons Inc.
T2  - Journal of Biomedical Materials Research - Part A
T1  - Electrospun polycaprolactone nanofibers functionalized with Achillea millefolium extract yield biomaterial with antibacterial, antioxidant and improved mechanical properties
EP  - 974
IS  - 7
SP  - 962
VL  - 111
DO  - 10.1002/jbm.a.37481
ER  - 

@article{
author = "Radisavljević, Anđela and Stojanović, Dušica B. and Petrović, Miloš and Radojević, Vesna and Uskoković, Petar and Rajilić-Stojanović, Mirjana",
year = "2023",
abstract = "In this study, polycaprolactone (PCL), as a biocompatible polymer was functionalized by addition of medicinal plant extract- Achillea millefolium L. (yarrow). Nanofiber mats were fabricated from PCL solutions containing dry yarrow extract in four concentrations (5%, 10%, 15%, and 20% relative to the weight of the polymer) by using blend electrospinning method. The nanofibers were characterized for their biological, mechanical and drug release behavior. In vitro release of yarrow polyphenols from the electrospun PCL nanofibers over a period of 5 days showed the release of up to 98% of the total loaded polyphenols. The released polyphenols retained its antioxidant activity, which was determined by DPPH assay. Electrospun PCL/yarrow nanofiber mats exhibited the antibacterial effect against Staphylococcus aureus, but had no effect on the growth of Pseudomonas aeruginosa. All PCL/yarrow nanofiber mats had improved mechanical properties compared to the neat PCL nanofibers, as evident by an increase in Young's modulus of elasticity (up to 5.7 times), the tensile strength (up to 5.5 times), and the strain at break (up to 1.45 times). Based on our results, yarrow-loaded PCL nanofiber mats appeared to be multi-functional biomaterials suitable for the production of catheter-coating materials, patches, or gauzes with antibacterial and antioxidant properties.",
publisher = "John Wiley and Sons Inc.",
journal = "Journal of Biomedical Materials Research - Part A",
title = "Electrospun polycaprolactone nanofibers functionalized with Achillea millefolium extract yield biomaterial with antibacterial, antioxidant and improved mechanical properties",
pages = "974-962",
number = "7",
volume = "111",
doi = "10.1002/jbm.a.37481"
}

Radisavljević, A., Stojanović, D. B., Petrović, M., Radojević, V., Uskoković, P.,& Rajilić-Stojanović, M.. (2023). Electrospun polycaprolactone nanofibers functionalized with Achillea millefolium extract yield biomaterial with antibacterial, antioxidant and improved mechanical properties. in Journal of Biomedical Materials Research - Part A
John Wiley and Sons Inc.., 111(7), 962-974.
https://doi.org/10.1002/jbm.a.37481

Radisavljević A, Stojanović DB, Petrović M, Radojević V, Uskoković P, Rajilić-Stojanović M. Electrospun polycaprolactone nanofibers functionalized with Achillea millefolium extract yield biomaterial with antibacterial, antioxidant and improved mechanical properties. in Journal of Biomedical Materials Research - Part A. 2023;111(7):962-974.
doi:10.1002/jbm.a.37481 .

Radisavljević, Anđela, Stojanović, Dušica B., Petrović, Miloš, Radojević, Vesna, Uskoković, Petar, Rajilić-Stojanović, Mirjana, "Electrospun polycaprolactone nanofibers functionalized with Achillea millefolium extract yield biomaterial with antibacterial, antioxidant and improved mechanical properties" in Journal of Biomedical Materials Research - Part A, 111, no. 7 (2023):962-974,
https://doi.org/10.1002/jbm.a.37481 . .

TY  - JOUR
AU  - Radisavljević, Anđela
AU  - Milutinović, Milica
AU  - Dimitrijević-Branković, Suzana
AU  - Uskoković, Petar
AU  - Rajilić-Stojanović, Mirjana
PY  - 2021
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4948
AB  - In this study, a spray drying process of yarrow (Achillea millefolium L.) liquid extracts was optimized by using the response surface methodology. The study aimed to determine the influence of temperature (120-195 degrees C), liquid flow rate (3-16.5 cm(3) min(-1)) and dry matter content in the liquid extract (0.3-1.5 %) on the yield of the drying process, the total polyphenols content and the antioxidant activity of the dry powder. Under the tested conditions the yield varied dramatically and ranged from 8 to 75 %, while the effects on the polyphenol content and antioxidant activity were lower. The optimized conditions for the maximum antioxidant activity and maximal yield of the dried extract were as follows: temperature of 130 degrees C, liquid flow rate of 7.5 cm(3) min(-1) and dry matter content of 1.2 %. Under the optimal conditions, the yield was 66 %, while there was a slight decrease in the polyphenol content in the dried extract as compared to that in the liquid extract (145 mg of gallic acid equivalents [GAE] per g of the total dry matter vs. 152 mg GAE g(-1), respectively). Consequently, antioxidant activity of the dry powder was only slightly reduced as compared to that of the liquid extract (DPPH neutralization was 58 vs. 64 %, respectively). The dried yarrow powder preserved its antimicrobial activity against pathogenic bacteria Staphylococcus aureus (MIC value of 10 mg cm(-3)) and Pseudomonas aeruginosa (MIC value of 20 mg cm(-3)).
T2  - Hemijska industrija
T1  - Optimization of spray drying conditions for production of Achillea millefolium extract powder
EP  - 363
IS  - 6
SP  - 353
VL  - 75
DO  - 10.2298/HEMIND210527030R
ER  - 

@article{
author = "Radisavljević, Anđela and Milutinović, Milica and Dimitrijević-Branković, Suzana and Uskoković, Petar and Rajilić-Stojanović, Mirjana",
year = "2021",
abstract = "In this study, a spray drying process of yarrow (Achillea millefolium L.) liquid extracts was optimized by using the response surface methodology. The study aimed to determine the influence of temperature (120-195 degrees C), liquid flow rate (3-16.5 cm(3) min(-1)) and dry matter content in the liquid extract (0.3-1.5 %) on the yield of the drying process, the total polyphenols content and the antioxidant activity of the dry powder. Under the tested conditions the yield varied dramatically and ranged from 8 to 75 %, while the effects on the polyphenol content and antioxidant activity were lower. The optimized conditions for the maximum antioxidant activity and maximal yield of the dried extract were as follows: temperature of 130 degrees C, liquid flow rate of 7.5 cm(3) min(-1) and dry matter content of 1.2 %. Under the optimal conditions, the yield was 66 %, while there was a slight decrease in the polyphenol content in the dried extract as compared to that in the liquid extract (145 mg of gallic acid equivalents [GAE] per g of the total dry matter vs. 152 mg GAE g(-1), respectively). Consequently, antioxidant activity of the dry powder was only slightly reduced as compared to that of the liquid extract (DPPH neutralization was 58 vs. 64 %, respectively). The dried yarrow powder preserved its antimicrobial activity against pathogenic bacteria Staphylococcus aureus (MIC value of 10 mg cm(-3)) and Pseudomonas aeruginosa (MIC value of 20 mg cm(-3)).",
journal = "Hemijska industrija",
title = "Optimization of spray drying conditions for production of Achillea millefolium extract powder",
pages = "363-353",
number = "6",
volume = "75",
doi = "10.2298/HEMIND210527030R"
}

Radisavljević, A., Milutinović, M., Dimitrijević-Branković, S., Uskoković, P.,& Rajilić-Stojanović, M.. (2021). Optimization of spray drying conditions for production of Achillea millefolium extract powder. in Hemijska industrija, 75(6), 353-363.
https://doi.org/10.2298/HEMIND210527030R

Radisavljević A, Milutinović M, Dimitrijević-Branković S, Uskoković P, Rajilić-Stojanović M. Optimization of spray drying conditions for production of Achillea millefolium extract powder. in Hemijska industrija. 2021;75(6):353-363.
doi:10.2298/HEMIND210527030R .

Radisavljević, Anđela, Milutinović, Milica, Dimitrijević-Branković, Suzana, Uskoković, Petar, Rajilić-Stojanović, Mirjana, "Optimization of spray drying conditions for production of Achillea millefolium extract powder" in Hemijska industrija, 75, no. 6 (2021):353-363,
https://doi.org/10.2298/HEMIND210527030R . .

TY  - CONF
AU  - Jovanović, Marija N.
AU  - Radisavljević, Anđela N.
AU  - Petrović, Miloš M.
AU  - Stojanović, Dušica B.
AU  - Ibrić, Svetlana R.
AU  - Uskoković, Petar S.
PY  - 2021
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/6078
AB  - The oral mucoadhesive film is a novel and attractive formulation for local and/or systemic drug
delivery through the mucosal membrane of the oral cavity. Certain active pharmaceutical ingredients (API) in conventional formulations (tablets, capsules, syrups) are absorbed in the gastrointestinal tract and undergo first-pass metabolism through the liver, thereby reducing their bioavailability. This problem can be overcome by using intraoral formulations, such as mucoadhesive buccal films that disintegrate and dissolve in the oral cavity where the absorption of API occurs. In this work, the mucoadhesive films were prepared by 3D paste printing and the influence of processing parameters on film properties and the release rate of a drug was investigated. Gelatin (GA) and the blend of gelatin/polyvinylpyrrolidone (GA/PVP) were used because of their biocompatibility. Propranolol hydrochloride (PRH) was used as a model substance because it has high first-pass metabolism and is soluble in water. Film morphology and drug distribution were followed by SEM analysis. Dissolution test in simulated saliva was done to see how PRH was released from films. Mucoadhesion test revealed that the GA/PVP films with PRH have the highest adhesion force. Obtained results introduce GA/PVP as a promising material with good adhesion and rate of drug release.
PB  - Belgrade : Materials Research Society of Serbia
C3  - Twenty-second Annual Conference YUCOMAT 2021, Herceg Novi, Montenegro
T1  - 3D printed mucoadhesive gelatin based buccal films
SP  - 122
UR  - https://hdl.handle.net/21.15107/rcub_technorep_6078
ER  - 

@conference{
author = "Jovanović, Marija N. and Radisavljević, Anđela N. and Petrović, Miloš M. and Stojanović, Dušica B. and Ibrić, Svetlana R. and Uskoković, Petar S.",
year = "2021",
abstract = "The oral mucoadhesive film is a novel and attractive formulation for local and/or systemic drug
delivery through the mucosal membrane of the oral cavity. Certain active pharmaceutical ingredients (API) in conventional formulations (tablets, capsules, syrups) are absorbed in the gastrointestinal tract and undergo first-pass metabolism through the liver, thereby reducing their bioavailability. This problem can be overcome by using intraoral formulations, such as mucoadhesive buccal films that disintegrate and dissolve in the oral cavity where the absorption of API occurs. In this work, the mucoadhesive films were prepared by 3D paste printing and the influence of processing parameters on film properties and the release rate of a drug was investigated. Gelatin (GA) and the blend of gelatin/polyvinylpyrrolidone (GA/PVP) were used because of their biocompatibility. Propranolol hydrochloride (PRH) was used as a model substance because it has high first-pass metabolism and is soluble in water. Film morphology and drug distribution were followed by SEM analysis. Dissolution test in simulated saliva was done to see how PRH was released from films. Mucoadhesion test revealed that the GA/PVP films with PRH have the highest adhesion force. Obtained results introduce GA/PVP as a promising material with good adhesion and rate of drug release.",
publisher = "Belgrade : Materials Research Society of Serbia",
journal = "Twenty-second Annual Conference YUCOMAT 2021, Herceg Novi, Montenegro",
title = "3D printed mucoadhesive gelatin based buccal films",
pages = "122",
url = "https://hdl.handle.net/21.15107/rcub_technorep_6078"
}

Jovanović, M. N., Radisavljević, A. N., Petrović, M. M., Stojanović, D. B., Ibrić, S. R.,& Uskoković, P. S.. (2021). 3D printed mucoadhesive gelatin based buccal films. in Twenty-second Annual Conference YUCOMAT 2021, Herceg Novi, Montenegro
Belgrade : Materials Research Society of Serbia., 122.
https://hdl.handle.net/21.15107/rcub_technorep_6078

Jovanović MN, Radisavljević AN, Petrović MM, Stojanović DB, Ibrić SR, Uskoković PS. 3D printed mucoadhesive gelatin based buccal films. in Twenty-second Annual Conference YUCOMAT 2021, Herceg Novi, Montenegro. 2021;:122.
https://hdl.handle.net/21.15107/rcub_technorep_6078 .

Jovanović, Marija N., Radisavljević, Anđela N., Petrović, Miloš M., Stojanović, Dušica B., Ibrić, Svetlana R., Uskoković, Petar S., "3D printed mucoadhesive gelatin based buccal films" in Twenty-second Annual Conference YUCOMAT 2021, Herceg Novi, Montenegro (2021):122,
https://hdl.handle.net/21.15107/rcub_technorep_6078 .

TY  - JOUR
AU  - Abozaid, Rouaida Mohamed
AU  - Stojanović, Dušica
AU  - Radisavljević, Anđela
AU  - Sević, Dragutin M.
AU  - Rabasović, Maja S.
AU  - Radović, I. M.
AU  - Radojević, Vesna
PY  - 2020
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4573
AB  - Processing and characterization of polymer nanocomposites based on poly(methyl methacrylate) (PMMA) matrix with embedded core-shell CdSe/ZnS quantum dots were investigated. Nanocomposites were obtained via solution casting and electrospinning. FESEM analysis revealed that the processing with electrospinning enables better dispersion of quantum dots. Time-resolved laser induced fluorescence measurements confirmed uniform size of QDs in fibers with the emission at only one wavelength. Oxidation effects in quantum dots were removed with the use of PMMA as a host, and the core remained active, which was confirmed with FTIR analysis and time-resolved laser induced fluorescence measurements.
PB  - Natl Inst Optoelectronics, Bucharest-Magurele
T2  - Journal of Optoelectronics and Advanced Materials
T1  - Polymer composite films and nanofibers doped with core-shell quantum dots
EP  - 74
IS  - 1-2
SP  - 67
VL  - 22
UR  - https://hdl.handle.net/21.15107/rcub_vinar_9034
ER  - 

@article{
author = "Abozaid, Rouaida Mohamed and Stojanović, Dušica and Radisavljević, Anđela and Sević, Dragutin M. and Rabasović, Maja S. and Radović, I. M. and Radojević, Vesna",
year = "2020",
abstract = "Processing and characterization of polymer nanocomposites based on poly(methyl methacrylate) (PMMA) matrix with embedded core-shell CdSe/ZnS quantum dots were investigated. Nanocomposites were obtained via solution casting and electrospinning. FESEM analysis revealed that the processing with electrospinning enables better dispersion of quantum dots. Time-resolved laser induced fluorescence measurements confirmed uniform size of QDs in fibers with the emission at only one wavelength. Oxidation effects in quantum dots were removed with the use of PMMA as a host, and the core remained active, which was confirmed with FTIR analysis and time-resolved laser induced fluorescence measurements.",
publisher = "Natl Inst Optoelectronics, Bucharest-Magurele",
journal = "Journal of Optoelectronics and Advanced Materials",
title = "Polymer composite films and nanofibers doped with core-shell quantum dots",
pages = "74-67",
number = "1-2",
volume = "22",
url = "https://hdl.handle.net/21.15107/rcub_vinar_9034"
}

Abozaid, R. M., Stojanović, D., Radisavljević, A., Sević, D. M., Rabasović, M. S., Radović, I. M.,& Radojević, V.. (2020). Polymer composite films and nanofibers doped with core-shell quantum dots. in Journal of Optoelectronics and Advanced Materials
Natl Inst Optoelectronics, Bucharest-Magurele., 22(1-2), 67-74.
https://hdl.handle.net/21.15107/rcub_vinar_9034

Abozaid RM, Stojanović D, Radisavljević A, Sević DM, Rabasović MS, Radović IM, Radojević V. Polymer composite films and nanofibers doped with core-shell quantum dots. in Journal of Optoelectronics and Advanced Materials. 2020;22(1-2):67-74.
https://hdl.handle.net/21.15107/rcub_vinar_9034 .

Abozaid, Rouaida Mohamed, Stojanović, Dušica, Radisavljević, Anđela, Sević, Dragutin M., Rabasović, Maja S., Radović, I. M., Radojević, Vesna, "Polymer composite films and nanofibers doped with core-shell quantum dots" in Journal of Optoelectronics and Advanced Materials, 22, no. 1-2 (2020):67-74,
https://hdl.handle.net/21.15107/rcub_vinar_9034 .

TY  - JOUR
AU  - Radović, Ivana
AU  - Stajčić, Aleksandar
AU  - Radisavljević, Anđela
AU  - Veljković, Filip M.
AU  - Čebela, Maria
AU  - Mitić, Vojislav V.
AU  - Radojević, Vesna
PY  - 2020
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4435
AB  - Nowadays, there is a very high importance of composite research and variety of their applications in the modern world. In that sense, we researched hollow glass capillaries filled with dissolved Grubbs catalyst (GC) and dicyclopentadiene (DCPD) were incorporated into a fiber-reinforced epoxy with the aim of improving the flow of healing agents to the crack site. The morphological investigation of the crack site was performed using field emission scanning electron microscopy (FESEM), showing the difference between the samples depending on the used solvent. The software analysis of sample photographs has been performed by calculating the fractured/healed surface area of the samples, revealing that approximately 20% of the volume was affected by the impact. Fourier transform infrared spectroscopy (FTIR) revealed that poly (dicyclopentadiene) (PDCPD) formed at the healed interface. However, the FTIR investigation of catalyst stability in different solvents showed structural changes in GC and partial deactivation. The mechanical tests of the samples showed that a recovery of 60% after 24 h at room temperature could be achieved through the use of a solvent and very low concentration of GC. The performed research results are a good base to develop the model for predicting the processes and morphology, with the goal to design the final mechanical and in the future, thermal, properties in advance. This opens a new direction for future research in the field of composite healing.
PB  - Elsevier Science Sa, Lausanne
T2  - Materials Chemistry and Physics
T1  - Solvent effects on structural changes in self-healing epoxy composites
VL  - 256
DO  - 10.1016/j.matchemphys.2020.123761
ER  - 

@article{
author = "Radović, Ivana and Stajčić, Aleksandar and Radisavljević, Anđela and Veljković, Filip M. and Čebela, Maria and Mitić, Vojislav V. and Radojević, Vesna",
year = "2020",
abstract = "Nowadays, there is a very high importance of composite research and variety of their applications in the modern world. In that sense, we researched hollow glass capillaries filled with dissolved Grubbs catalyst (GC) and dicyclopentadiene (DCPD) were incorporated into a fiber-reinforced epoxy with the aim of improving the flow of healing agents to the crack site. The morphological investigation of the crack site was performed using field emission scanning electron microscopy (FESEM), showing the difference between the samples depending on the used solvent. The software analysis of sample photographs has been performed by calculating the fractured/healed surface area of the samples, revealing that approximately 20% of the volume was affected by the impact. Fourier transform infrared spectroscopy (FTIR) revealed that poly (dicyclopentadiene) (PDCPD) formed at the healed interface. However, the FTIR investigation of catalyst stability in different solvents showed structural changes in GC and partial deactivation. The mechanical tests of the samples showed that a recovery of 60% after 24 h at room temperature could be achieved through the use of a solvent and very low concentration of GC. The performed research results are a good base to develop the model for predicting the processes and morphology, with the goal to design the final mechanical and in the future, thermal, properties in advance. This opens a new direction for future research in the field of composite healing.",
publisher = "Elsevier Science Sa, Lausanne",
journal = "Materials Chemistry and Physics",
title = "Solvent effects on structural changes in self-healing epoxy composites",
volume = "256",
doi = "10.1016/j.matchemphys.2020.123761"
}

Radović, I., Stajčić, A., Radisavljević, A., Veljković, F. M., Čebela, M., Mitić, V. V.,& Radojević, V.. (2020). Solvent effects on structural changes in self-healing epoxy composites. in Materials Chemistry and Physics
Elsevier Science Sa, Lausanne., 256.
https://doi.org/10.1016/j.matchemphys.2020.123761

Radović I, Stajčić A, Radisavljević A, Veljković FM, Čebela M, Mitić VV, Radojević V. Solvent effects on structural changes in self-healing epoxy composites. in Materials Chemistry and Physics. 2020;256.
doi:10.1016/j.matchemphys.2020.123761 .

Radović, Ivana, Stajčić, Aleksandar, Radisavljević, Anđela, Veljković, Filip M., Čebela, Maria, Mitić, Vojislav V., Radojević, Vesna, "Solvent effects on structural changes in self-healing epoxy composites" in Materials Chemistry and Physics, 256 (2020),
https://doi.org/10.1016/j.matchemphys.2020.123761 . .

TY  - JOUR
AU  - Perišić, Srđan
AU  - Vuksanović, Marija M.
AU  - Petrović, Miloš
AU  - Radisavljević, Anđela
AU  - Grujić, Aleksandar
AU  - Jančić-Heinemann, Radmila
AU  - Radojević, Vesna
PY  - 2019
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4144
AB  - Hybrid composite panels of Wood-Plastic Composites (WPC) consisting of wood and poly (methyl methacrylate) (PMMA) were reinforced with alumina particles and made by "hot pressing" method. Alumina-based particles were made by sol-gel technique. The particles were characterized by the X-ray diffraction (XRD). The resulting alumina particles were modified with (3mercaptopropyl) trimethoxysilane (MPTMS), in order to obtain better mechanical properties of the composite relative to the composite with unmodified alumina particles. The aim of this work was to study the influence of composite structure and the moisture absorption on bending and the impact properties of the hybrid composite. The bending and impact tests revealed that modulus of elasticity and absorbed energy of deformation increased with modification of alumina and slightly decrease after moisture absorption.
PB  - Međunarodni Institut za nauku o sinterovanju, Beograd
T2  - Science of Sintering
T1  - Impact of Alumina Particles on the Morphology and Mechanics of Hybrid Wood Plastic Composite Materials
EP  - 124
IS  - 1
SP  - 115
VL  - 51
DO  - 10.2298/SOS1901115P
ER  - 

@article{
author = "Perišić, Srđan and Vuksanović, Marija M. and Petrović, Miloš and Radisavljević, Anđela and Grujić, Aleksandar and Jančić-Heinemann, Radmila and Radojević, Vesna",
year = "2019",
abstract = "Hybrid composite panels of Wood-Plastic Composites (WPC) consisting of wood and poly (methyl methacrylate) (PMMA) were reinforced with alumina particles and made by "hot pressing" method. Alumina-based particles were made by sol-gel technique. The particles were characterized by the X-ray diffraction (XRD). The resulting alumina particles were modified with (3mercaptopropyl) trimethoxysilane (MPTMS), in order to obtain better mechanical properties of the composite relative to the composite with unmodified alumina particles. The aim of this work was to study the influence of composite structure and the moisture absorption on bending and the impact properties of the hybrid composite. The bending and impact tests revealed that modulus of elasticity and absorbed energy of deformation increased with modification of alumina and slightly decrease after moisture absorption.",
publisher = "Međunarodni Institut za nauku o sinterovanju, Beograd",
journal = "Science of Sintering",
title = "Impact of Alumina Particles on the Morphology and Mechanics of Hybrid Wood Plastic Composite Materials",
pages = "124-115",
number = "1",
volume = "51",
doi = "10.2298/SOS1901115P"
}

Perišić, S., Vuksanović, M. M., Petrović, M., Radisavljević, A., Grujić, A., Jančić-Heinemann, R.,& Radojević, V.. (2019). Impact of Alumina Particles on the Morphology and Mechanics of Hybrid Wood Plastic Composite Materials. in Science of Sintering
Međunarodni Institut za nauku o sinterovanju, Beograd., 51(1), 115-124.
https://doi.org/10.2298/SOS1901115P

Perišić S, Vuksanović MM, Petrović M, Radisavljević A, Grujić A, Jančić-Heinemann R, Radojević V. Impact of Alumina Particles on the Morphology and Mechanics of Hybrid Wood Plastic Composite Materials. in Science of Sintering. 2019;51(1):115-124.
doi:10.2298/SOS1901115P .

Perišić, Srđan, Vuksanović, Marija M., Petrović, Miloš, Radisavljević, Anđela, Grujić, Aleksandar, Jančić-Heinemann, Radmila, Radojević, Vesna, "Impact of Alumina Particles on the Morphology and Mechanics of Hybrid Wood Plastic Composite Materials" in Science of Sintering, 51, no. 1 (2019):115-124,
https://doi.org/10.2298/SOS1901115P . .

TY  - JOUR
AU  - Radisavljević, Anđela
AU  - Stojanović, Dušica
AU  - Perišić, Srđan
AU  - Đokić, Veljko
AU  - Radojević, Vesna
AU  - Rajilić-Stojanović, Mirjana
AU  - Uskoković, Petar
PY  - 2018
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3931
AB  - Antibiotic containing polycaprolactone (PCL) fibers were produced by using three electrospinning methods: blend, emulsion and co-axial electrospinning (labeled as S1, S2 and S3, respectively). The profiles of drug release from three different systems were studied and antimicrobial properties of produced materials were evaluated. Morphology of the produced fibers was characterized and revealed that cefazolin-loaded PCL fibers had smaller diameter compared to neat PCL fibers, while the chemical interaction between the antibiotic and PCL showed that cefazolin neither had reacted with PCL phase, nor had degraded during the electrospinning process. The crystallinity and thermal characterization of fabricated fibers showed that the addition of cefazolin decreased the crystallinity of PCL. The results of the drug release behavior of the blend and co-axial electrospun fibers was on a higher level (similar to 68% and similar to 43%, respectively) compared to the emulsion electrospun fibers (similar to 5%), after a period of 30 days. The obtained data had the best fitting with the first order model and the Higuchi model, while the Korsmeyer-Peppas model showed a Pseudo-Fickian diffusion of the drug. Antibacterial evaluations showed that cefazolin-loaded PCL fibers had better effects on Staphylococcus aureus compared to Escherichia coll. during the treatment period and that the effect of the emulsion fibers was notably weaker than the other two studied systems. The aim of the study was to test different systems for control drug release of different dynamics, which will be applied for prevent bacterial accumulation when indwelling urinary catheters, applied for different periods of time.
PB  - Elsevier, Amsterdam
T2  - European Journal of Pharmaceutical Sciences
T1  - Cefazolin-loaded polycaprolactone fibers produced via different electrospinning methods: Characterization, drug release and antibacterial effect
EP  - 36
SP  - 26
VL  - 124
DO  - 10.1016/j.ejps.2018.08.023
ER  - 

@article{
author = "Radisavljević, Anđela and Stojanović, Dušica and Perišić, Srđan and Đokić, Veljko and Radojević, Vesna and Rajilić-Stojanović, Mirjana and Uskoković, Petar",
year = "2018",
abstract = "Antibiotic containing polycaprolactone (PCL) fibers were produced by using three electrospinning methods: blend, emulsion and co-axial electrospinning (labeled as S1, S2 and S3, respectively). The profiles of drug release from three different systems were studied and antimicrobial properties of produced materials were evaluated. Morphology of the produced fibers was characterized and revealed that cefazolin-loaded PCL fibers had smaller diameter compared to neat PCL fibers, while the chemical interaction between the antibiotic and PCL showed that cefazolin neither had reacted with PCL phase, nor had degraded during the electrospinning process. The crystallinity and thermal characterization of fabricated fibers showed that the addition of cefazolin decreased the crystallinity of PCL. The results of the drug release behavior of the blend and co-axial electrospun fibers was on a higher level (similar to 68% and similar to 43%, respectively) compared to the emulsion electrospun fibers (similar to 5%), after a period of 30 days. The obtained data had the best fitting with the first order model and the Higuchi model, while the Korsmeyer-Peppas model showed a Pseudo-Fickian diffusion of the drug. Antibacterial evaluations showed that cefazolin-loaded PCL fibers had better effects on Staphylococcus aureus compared to Escherichia coll. during the treatment period and that the effect of the emulsion fibers was notably weaker than the other two studied systems. The aim of the study was to test different systems for control drug release of different dynamics, which will be applied for prevent bacterial accumulation when indwelling urinary catheters, applied for different periods of time.",
publisher = "Elsevier, Amsterdam",
journal = "European Journal of Pharmaceutical Sciences",
title = "Cefazolin-loaded polycaprolactone fibers produced via different electrospinning methods: Characterization, drug release and antibacterial effect",
pages = "36-26",
volume = "124",
doi = "10.1016/j.ejps.2018.08.023"
}

Radisavljević, A., Stojanović, D., Perišić, S., Đokić, V., Radojević, V., Rajilić-Stojanović, M.,& Uskoković, P.. (2018). Cefazolin-loaded polycaprolactone fibers produced via different electrospinning methods: Characterization, drug release and antibacterial effect. in European Journal of Pharmaceutical Sciences
Elsevier, Amsterdam., 124, 26-36.
https://doi.org/10.1016/j.ejps.2018.08.023

Radisavljević A, Stojanović D, Perišić S, Đokić V, Radojević V, Rajilić-Stojanović M, Uskoković P. Cefazolin-loaded polycaprolactone fibers produced via different electrospinning methods: Characterization, drug release and antibacterial effect. in European Journal of Pharmaceutical Sciences. 2018;124:26-36.
doi:10.1016/j.ejps.2018.08.023 .

Radisavljević, Anđela, Stojanović, Dušica, Perišić, Srđan, Đokić, Veljko, Radojević, Vesna, Rajilić-Stojanović, Mirjana, Uskoković, Petar, "Cefazolin-loaded polycaprolactone fibers produced via different electrospinning methods: Characterization, drug release and antibacterial effect" in European Journal of Pharmaceutical Sciences, 124 (2018):26-36,
https://doi.org/10.1016/j.ejps.2018.08.023 . .

TY  - JOUR
AU  - Milosević, Miljan
AU  - Stojanović, Dušica
AU  - Simić, Vladimir
AU  - Milicević, Bogdan
AU  - Radisavljević, Anđela
AU  - Uskoković, Petar
AU  - Kojić, Miloš
PY  - 2018
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3912
AB  - Due to the relative ease of producing nanofibers with a core-shell structure, emulsion electrospinning has been investigated intensively in making nanofibrous drug delivery systems for controlled and sustained release. Predictions of drug release rates from the poly (D, L-lactic-co-glycolic acid) (PLGA) produced via emulsion electrospinning can be a very difficult task due to the complexity of the system. A computational finite element methodology was used to calculate the diffusion mass transport of Rhodamine B (fluorescent drug model). Degradation effects and hydrophobicity (partitioning phenomenon) at the fiber/surrounding interface were included in the models. The results are validated by experiments where electrospun PLGA nanofiber mats with different contents were used. A new approach to three-dimensional (3D) modeling of nanofibers is presented in this work. The authors have introduced two original models for diffusive drug release from nanofibers to the 3D surrounding medium discretized by continuum 3D finite elements: (1) A model with simple radial one-dimensional (1D) finite elements, and (2) a model consisting of composite smeared finite elements (CSFEs). Numerical solutions, compared to experiments, demonstrate that both computational models provide accurate predictions of the diffusion process and can therefore serve as efficient tools for describing transport inside a polymer fiber network and drug release to the surrounding porous medium.
PB  - MDPI, Basel
T2  - Materials
T1  - A Computational Model for Drug Release from PLGA Implant
IS  - 12
VL  - 11
DO  - 10.3390/ma11122416
ER  - 

@article{
author = "Milosević, Miljan and Stojanović, Dušica and Simić, Vladimir and Milicević, Bogdan and Radisavljević, Anđela and Uskoković, Petar and Kojić, Miloš",
year = "2018",
abstract = "Due to the relative ease of producing nanofibers with a core-shell structure, emulsion electrospinning has been investigated intensively in making nanofibrous drug delivery systems for controlled and sustained release. Predictions of drug release rates from the poly (D, L-lactic-co-glycolic acid) (PLGA) produced via emulsion electrospinning can be a very difficult task due to the complexity of the system. A computational finite element methodology was used to calculate the diffusion mass transport of Rhodamine B (fluorescent drug model). Degradation effects and hydrophobicity (partitioning phenomenon) at the fiber/surrounding interface were included in the models. The results are validated by experiments where electrospun PLGA nanofiber mats with different contents were used. A new approach to three-dimensional (3D) modeling of nanofibers is presented in this work. The authors have introduced two original models for diffusive drug release from nanofibers to the 3D surrounding medium discretized by continuum 3D finite elements: (1) A model with simple radial one-dimensional (1D) finite elements, and (2) a model consisting of composite smeared finite elements (CSFEs). Numerical solutions, compared to experiments, demonstrate that both computational models provide accurate predictions of the diffusion process and can therefore serve as efficient tools for describing transport inside a polymer fiber network and drug release to the surrounding porous medium.",
publisher = "MDPI, Basel",
journal = "Materials",
title = "A Computational Model for Drug Release from PLGA Implant",
number = "12",
volume = "11",
doi = "10.3390/ma11122416"
}

Milosević, M., Stojanović, D., Simić, V., Milicević, B., Radisavljević, A., Uskoković, P.,& Kojić, M.. (2018). A Computational Model for Drug Release from PLGA Implant. in Materials
MDPI, Basel., 11(12).
https://doi.org/10.3390/ma11122416

Milosević M, Stojanović D, Simić V, Milicević B, Radisavljević A, Uskoković P, Kojić M. A Computational Model for Drug Release from PLGA Implant. in Materials. 2018;11(12).
doi:10.3390/ma11122416 .

Milosević, Miljan, Stojanović, Dušica, Simić, Vladimir, Milicević, Bogdan, Radisavljević, Anđela, Uskoković, Petar, Kojić, Miloš, "A Computational Model for Drug Release from PLGA Implant" in Materials, 11, no. 12 (2018),
https://doi.org/10.3390/ma11122416 . .