TY  - JOUR
AU  - Dimitrijević, Snežana
AU  - Pavlović, Marija
AU  - Maksimović, Svetolik
AU  - Ristić, Mihailo S.
AU  - Filipović, Vladimir
AU  - Antonović, Dušan
AU  - Dimitrijević-Branković, Suzana
PY  - 2018
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3995
AB  - BACKGROUNDIn order to study the influence of plant growth-promoting bacteria (PGPB) belonging to Streptomyces sp., Paenibacillus sp., and Hymenobacter sp. on fixed oil content of flaxseed and black cumin, 2-year field experiments were conducted. PGPB was applied during seedtime of plants. The extraction of oil from seeds was performed using supercritical CO2. RESULTSThe addition of PGPB significantly increases the content of C18:1 (from 16.060.03% to 16.97 +/- 0.03%) and C18:3 (from 42.97 +/- 0.2% to 45.42 +/- 0.5%) in flaxseed oil and C18:2 (from 52.68 +/- 0.50% to 57.11 +/- 0.40%) and C20:2 (from 4.34 +/- 0.02% to 4.54 +/- 0.03%) in black cumin seed oil. The contents of total polyphenols, flavonoids, and carotenoids, as well as antioxidant activity measured by ferric-reducing ability of plasma assay, were found to be greater in the oil from the seeds of plants treated with the PGPB, compared with the respective non-treated samples. CONCLUSIONThe use of PGPB enhances plant nutritive properties; these represent a great source for obtaining valuable functional food ingredients.
PB  - Wiley, Hoboken
T2  - Journal of the Science of Food and Agriculture
T1  - Plant growth-promoting bacteria elevate the nutritional and functional properties of black cumin and flaxseed fixed oil
EP  - 1590
IS  - 4
SP  - 1584
VL  - 98
DO  - 10.1002/jsfa.8631
ER  - 

@article{
author = "Dimitrijević, Snežana and Pavlović, Marija and Maksimović, Svetolik and Ristić, Mihailo S. and Filipović, Vladimir and Antonović, Dušan and Dimitrijević-Branković, Suzana",
year = "2018",
abstract = "BACKGROUNDIn order to study the influence of plant growth-promoting bacteria (PGPB) belonging to Streptomyces sp., Paenibacillus sp., and Hymenobacter sp. on fixed oil content of flaxseed and black cumin, 2-year field experiments were conducted. PGPB was applied during seedtime of plants. The extraction of oil from seeds was performed using supercritical CO2. RESULTSThe addition of PGPB significantly increases the content of C18:1 (from 16.060.03% to 16.97 +/- 0.03%) and C18:3 (from 42.97 +/- 0.2% to 45.42 +/- 0.5%) in flaxseed oil and C18:2 (from 52.68 +/- 0.50% to 57.11 +/- 0.40%) and C20:2 (from 4.34 +/- 0.02% to 4.54 +/- 0.03%) in black cumin seed oil. The contents of total polyphenols, flavonoids, and carotenoids, as well as antioxidant activity measured by ferric-reducing ability of plasma assay, were found to be greater in the oil from the seeds of plants treated with the PGPB, compared with the respective non-treated samples. CONCLUSIONThe use of PGPB enhances plant nutritive properties; these represent a great source for obtaining valuable functional food ingredients.",
publisher = "Wiley, Hoboken",
journal = "Journal of the Science of Food and Agriculture",
title = "Plant growth-promoting bacteria elevate the nutritional and functional properties of black cumin and flaxseed fixed oil",
pages = "1590-1584",
number = "4",
volume = "98",
doi = "10.1002/jsfa.8631"
}

Dimitrijević, S., Pavlović, M., Maksimović, S., Ristić, M. S., Filipović, V., Antonović, D.,& Dimitrijević-Branković, S.. (2018). Plant growth-promoting bacteria elevate the nutritional and functional properties of black cumin and flaxseed fixed oil. in Journal of the Science of Food and Agriculture
Wiley, Hoboken., 98(4), 1584-1590.
https://doi.org/10.1002/jsfa.8631

Dimitrijević S, Pavlović M, Maksimović S, Ristić MS, Filipović V, Antonović D, Dimitrijević-Branković S. Plant growth-promoting bacteria elevate the nutritional and functional properties of black cumin and flaxseed fixed oil. in Journal of the Science of Food and Agriculture. 2018;98(4):1584-1590.
doi:10.1002/jsfa.8631 .

Dimitrijević, Snežana, Pavlović, Marija, Maksimović, Svetolik, Ristić, Mihailo S., Filipović, Vladimir, Antonović, Dušan, Dimitrijević-Branković, Suzana, "Plant growth-promoting bacteria elevate the nutritional and functional properties of black cumin and flaxseed fixed oil" in Journal of the Science of Food and Agriculture, 98, no. 4 (2018):1584-1590,
https://doi.org/10.1002/jsfa.8631 . .

TY  - JOUR
AU  - Marković, Miljana S.
AU  - Radosavljević, Dragana B.
AU  - Pavićević, Vladimir
AU  - Ristić, Mihailo S.
AU  - Milojević, Svetomir
AU  - Bošković-Vragolović, Nevenka
AU  - Veljković, Vlada B.
PY  - 2018
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3845
AB  - The present paper dealt with the influence of the common juniper berries pretreatment on the yield, chemical composition and extraction kinetics of juniper essential oil (JEO) obtained by classical (HD) and microwave assisted hydrodistillation (MAHD). The highest JEO yield was obtained by HD from one-minute dry-ground juniper berries (2.23 +/- 0.00 g/100 g). No statistically significant influence of swelling and distillation technique on JEO yield was observed. Therefore, the optimal pretreatment process involved no swelling and one-minute grinding. However, no significant difference in the chemical composition of the JEOs obtained by the two techniques was observed. A new phenomenological kinetic model was developed on the basis of the mechanism of JEO extraction by both HD MAHD, which assumed three simultaneously-occurring stages: washing, unhindered diffusion and hindered diffusion. The main advantage of developed model was its ability to describe the variations of JEO yield and distillation rates with time. Furthermore, it had the smallest mean relative percentage deviation compared to the well-known kinetics models and the parameters that all were statistically significant, so it was recommended for modeling the kinetics of JEO extraction by HD and especially MAHD.
PB  - Elsevier Science Bv, Amsterdam
T2  - Industrial Crops and Products
T1  - Influence of common juniper berries pretreatment on the essential oil yield, chemical composition and extraction kinetics of classical and microwave assisted hydrodistillation
EP  - 413
SP  - 402
VL  - 122
DO  - 10.1016/j.indcrop.2018.06.018
ER  - 

@article{
author = "Marković, Miljana S. and Radosavljević, Dragana B. and Pavićević, Vladimir and Ristić, Mihailo S. and Milojević, Svetomir and Bošković-Vragolović, Nevenka and Veljković, Vlada B.",
year = "2018",
abstract = "The present paper dealt with the influence of the common juniper berries pretreatment on the yield, chemical composition and extraction kinetics of juniper essential oil (JEO) obtained by classical (HD) and microwave assisted hydrodistillation (MAHD). The highest JEO yield was obtained by HD from one-minute dry-ground juniper berries (2.23 +/- 0.00 g/100 g). No statistically significant influence of swelling and distillation technique on JEO yield was observed. Therefore, the optimal pretreatment process involved no swelling and one-minute grinding. However, no significant difference in the chemical composition of the JEOs obtained by the two techniques was observed. A new phenomenological kinetic model was developed on the basis of the mechanism of JEO extraction by both HD MAHD, which assumed three simultaneously-occurring stages: washing, unhindered diffusion and hindered diffusion. The main advantage of developed model was its ability to describe the variations of JEO yield and distillation rates with time. Furthermore, it had the smallest mean relative percentage deviation compared to the well-known kinetics models and the parameters that all were statistically significant, so it was recommended for modeling the kinetics of JEO extraction by HD and especially MAHD.",
publisher = "Elsevier Science Bv, Amsterdam",
journal = "Industrial Crops and Products",
title = "Influence of common juniper berries pretreatment on the essential oil yield, chemical composition and extraction kinetics of classical and microwave assisted hydrodistillation",
pages = "413-402",
volume = "122",
doi = "10.1016/j.indcrop.2018.06.018"
}

Marković, M. S., Radosavljević, D. B., Pavićević, V., Ristić, M. S., Milojević, S., Bošković-Vragolović, N.,& Veljković, V. B.. (2018). Influence of common juniper berries pretreatment on the essential oil yield, chemical composition and extraction kinetics of classical and microwave assisted hydrodistillation. in Industrial Crops and Products
Elsevier Science Bv, Amsterdam., 122, 402-413.
https://doi.org/10.1016/j.indcrop.2018.06.018

Marković MS, Radosavljević DB, Pavićević V, Ristić MS, Milojević S, Bošković-Vragolović N, Veljković VB. Influence of common juniper berries pretreatment on the essential oil yield, chemical composition and extraction kinetics of classical and microwave assisted hydrodistillation. in Industrial Crops and Products. 2018;122:402-413.
doi:10.1016/j.indcrop.2018.06.018 .

Marković, Miljana S., Radosavljević, Dragana B., Pavićević, Vladimir, Ristić, Mihailo S., Milojević, Svetomir, Bošković-Vragolović, Nevenka, Veljković, Vlada B., "Influence of common juniper berries pretreatment on the essential oil yield, chemical composition and extraction kinetics of classical and microwave assisted hydrodistillation" in Industrial Crops and Products, 122 (2018):402-413,
https://doi.org/10.1016/j.indcrop.2018.06.018 . .

TY  - JOUR
AU  - Marković, Miljana S.
AU  - Bošković-Vragolović, Nevenka
AU  - Ristić, Mihailo S.
AU  - Pavićević, Vladimir
AU  - Veljković, Vlada B.
AU  - Milojević, Svetomir
PY  - 2017
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3646
AB  - This paper deals with fractionation of the essential oil from juniper (Juniperus communis L.) berries by hydrodistillation (HD) and simultaneous hydrodistillation and rectification (SHDR) at atmospheric pressure. A rectification column was filled with the NORMAG packing A type and had 36 theoretical stages. In the present study, higher essential oil yield was obtained by HD (1.34 mass %) than by SHDR (1.17 mass %). However, mass fraction distributions of monoterpene hydrocarbons (MHs), oxygenated monoterpenes (OMs) and sesquiterpene hydrocarbons (SHs), observed for the two separation methods, differed from each other. In the SHDR process increased contents of high volatile components (predominantly MHs) were obtained in the initial fractions as well as increased contents of low volatile components (dominantly SHs) in the last fractions. Also, this method increased the separation degree of OMs.
PB  - Savez hemijskih inženjera, Beograd
T2  - Hemijska industrija
T1  - Fractionation of the essential oil from juniper (Juniperus communis L.) berries by hydrodistillation and rectification
EP  - 477
IS  - 6
SP  - 471
VL  - 71
DO  - 10.2298/HEMIND161204009M
ER  - 

@article{
author = "Marković, Miljana S. and Bošković-Vragolović, Nevenka and Ristić, Mihailo S. and Pavićević, Vladimir and Veljković, Vlada B. and Milojević, Svetomir",
year = "2017",
abstract = "This paper deals with fractionation of the essential oil from juniper (Juniperus communis L.) berries by hydrodistillation (HD) and simultaneous hydrodistillation and rectification (SHDR) at atmospheric pressure. A rectification column was filled with the NORMAG packing A type and had 36 theoretical stages. In the present study, higher essential oil yield was obtained by HD (1.34 mass %) than by SHDR (1.17 mass %). However, mass fraction distributions of monoterpene hydrocarbons (MHs), oxygenated monoterpenes (OMs) and sesquiterpene hydrocarbons (SHs), observed for the two separation methods, differed from each other. In the SHDR process increased contents of high volatile components (predominantly MHs) were obtained in the initial fractions as well as increased contents of low volatile components (dominantly SHs) in the last fractions. Also, this method increased the separation degree of OMs.",
publisher = "Savez hemijskih inženjera, Beograd",
journal = "Hemijska industrija",
title = "Fractionation of the essential oil from juniper (Juniperus communis L.) berries by hydrodistillation and rectification",
pages = "477-471",
number = "6",
volume = "71",
doi = "10.2298/HEMIND161204009M"
}

Marković, M. S., Bošković-Vragolović, N., Ristić, M. S., Pavićević, V., Veljković, V. B.,& Milojević, S.. (2017). Fractionation of the essential oil from juniper (Juniperus communis L.) berries by hydrodistillation and rectification. in Hemijska industrija
Savez hemijskih inženjera, Beograd., 71(6), 471-477.
https://doi.org/10.2298/HEMIND161204009M

Marković MS, Bošković-Vragolović N, Ristić MS, Pavićević V, Veljković VB, Milojević S. Fractionation of the essential oil from juniper (Juniperus communis L.) berries by hydrodistillation and rectification. in Hemijska industrija. 2017;71(6):471-477.
doi:10.2298/HEMIND161204009M .

Marković, Miljana S., Bošković-Vragolović, Nevenka, Ristić, Mihailo S., Pavićević, Vladimir, Veljković, Vlada B., Milojević, Svetomir, "Fractionation of the essential oil from juniper (Juniperus communis L.) berries by hydrodistillation and rectification" in Hemijska industrija, 71, no. 6 (2017):471-477,
https://doi.org/10.2298/HEMIND161204009M . .

TY  - JOUR
AU  - Durdević, Sanja
AU  - Milovanović, Stoja
AU  - Šavikin, Katarina
AU  - Ristić, Mihailo S.
AU  - Menković, Nebojša
AU  - Pljevljakusić, Dejan
AU  - Petrović, Slobodan
AU  - Bogdanović, Aleksandra
PY  - 2017
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3715
AB  - Microwave radiation was suggested as a pretreatment technique to increase the yield of pomegranate seed oil. Seeds were pretreated at 100, 250 and 600 W during 2 and 6 min and then extracted by supercritical carbon dioxide (scCO(2)) in high pressure unit as well as by n-hexane in Soxhlet apparatus. Even at the lowest microwave pretreatment parameters applied (100 W for 2 min) increased the yield of seed oil obtained by both extraction techniques compared with untreated seeds (from 27.7 to 34.0% and from 21.6 to 25.5% for Soxhlet and scCO(2) extractions, respectively). Maximal oil yield in Soxhlet extraction (36.3%) was obtained with microwave radiation of 600 W for 6 min while for scCO(2) extraction maximal oil yield (27.2%) was with 250 W for 6 min microwave radiation pretreatment. The qualitative and quantitative composition of fatty acids of the obtained oils was determined by gas chromatography/flame ionization detection and gas chromatography/mass spectrometry. Punicic acid was the most abundant fatty acid in pomegranate seed oil ( gt  60%). Microwave pretreatment of seeds showed negligible influence on profile and the amount of fatty acids in obtained extracts, compared with its significant influence on extraction yield. Our results recognize microwave pretreatment as a promising technique for intensification of oil extraction from pomegranate seeds.
PB  - Elsevier, Amsterdam
T2  - Industrial Crops and Products
T1  - Improvement of supercritical CO2 and n-hexane extraction of wild growing pomegranate seed oil by microwave pretreatment
EP  - 27
SP  - 21
VL  - 104
DO  - 10.1016/j.indcrop.2017.04.024
ER  - 

@article{
author = "Durdević, Sanja and Milovanović, Stoja and Šavikin, Katarina and Ristić, Mihailo S. and Menković, Nebojša and Pljevljakusić, Dejan and Petrović, Slobodan and Bogdanović, Aleksandra",
year = "2017",
abstract = "Microwave radiation was suggested as a pretreatment technique to increase the yield of pomegranate seed oil. Seeds were pretreated at 100, 250 and 600 W during 2 and 6 min and then extracted by supercritical carbon dioxide (scCO(2)) in high pressure unit as well as by n-hexane in Soxhlet apparatus. Even at the lowest microwave pretreatment parameters applied (100 W for 2 min) increased the yield of seed oil obtained by both extraction techniques compared with untreated seeds (from 27.7 to 34.0% and from 21.6 to 25.5% for Soxhlet and scCO(2) extractions, respectively). Maximal oil yield in Soxhlet extraction (36.3%) was obtained with microwave radiation of 600 W for 6 min while for scCO(2) extraction maximal oil yield (27.2%) was with 250 W for 6 min microwave radiation pretreatment. The qualitative and quantitative composition of fatty acids of the obtained oils was determined by gas chromatography/flame ionization detection and gas chromatography/mass spectrometry. Punicic acid was the most abundant fatty acid in pomegranate seed oil ( gt  60%). Microwave pretreatment of seeds showed negligible influence on profile and the amount of fatty acids in obtained extracts, compared with its significant influence on extraction yield. Our results recognize microwave pretreatment as a promising technique for intensification of oil extraction from pomegranate seeds.",
publisher = "Elsevier, Amsterdam",
journal = "Industrial Crops and Products",
title = "Improvement of supercritical CO2 and n-hexane extraction of wild growing pomegranate seed oil by microwave pretreatment",
pages = "27-21",
volume = "104",
doi = "10.1016/j.indcrop.2017.04.024"
}

Durdević, S., Milovanović, S., Šavikin, K., Ristić, M. S., Menković, N., Pljevljakusić, D., Petrović, S.,& Bogdanović, A.. (2017). Improvement of supercritical CO2 and n-hexane extraction of wild growing pomegranate seed oil by microwave pretreatment. in Industrial Crops and Products
Elsevier, Amsterdam., 104, 21-27.
https://doi.org/10.1016/j.indcrop.2017.04.024

Durdević S, Milovanović S, Šavikin K, Ristić MS, Menković N, Pljevljakusić D, Petrović S, Bogdanović A. Improvement of supercritical CO2 and n-hexane extraction of wild growing pomegranate seed oil by microwave pretreatment. in Industrial Crops and Products. 2017;104:21-27.
doi:10.1016/j.indcrop.2017.04.024 .

Durdević, Sanja, Milovanović, Stoja, Šavikin, Katarina, Ristić, Mihailo S., Menković, Nebojša, Pljevljakusić, Dejan, Petrović, Slobodan, Bogdanović, Aleksandra, "Improvement of supercritical CO2 and n-hexane extraction of wild growing pomegranate seed oil by microwave pretreatment" in Industrial Crops and Products, 104 (2017):21-27,
https://doi.org/10.1016/j.indcrop.2017.04.024 . .

TY  - JOUR
AU  - Pavićević, Vladimir
AU  - Radović, Marko N.
AU  - Milojević, Svetomir
AU  - Marković, Miljana S.
AU  - Ristić, Mihailo S.
AU  - Povrenović, Dragan
PY  - 2017
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3739
AB  - Essential oils are aromatic, volatile, complex mixtures of various compounds, mainly hydrocarbons (monoterpene and sesquiterpene) and some oxygenated hydrocarbons. Juniper berry essential oil has wide application and high commercial value due to its considerable antimicrobial activities. It is used in medicine, food, cosmetic and pharmaceutical industry and veterinary medicine. Generally, it is obtained by hydrodistillation, technique for the extraction of substances which do not mix or mix very poorly with water and are unstable at their boiling temperatures. It provides high quality of essential oil and also represents a relatively simple, safe and environmentally friendly process. The variations in the chemical composition of the essential oil obtained from juniper berries at various distillation rates (3, 6 and 8 ml/min) and various mass ratio juniper berries-water (hydromodules -1:3, 1: 4 and 1: 5) are presented in this paper. It is important to emphasize that the variations made influence only in quantitative (mass%), but not in qualitative chemical composition (no differences, same 58 components were detected in all experiments). To reflect those effects, only 23 identified components with the content higher than 0.5 mass% were selected, constituted 95-96 mass% of the essential oils. The major constituents of the essential oils were monoterpenes (67.39-71.00 mass%), followed by sesquiterpenes (21.64-24.54 mass%), while the oxygenated monoterpene (1.54-2.42 mas.%) and oxygenated sesquiterpenes (0.89-1.46 mass%) were much less present. According to volatility, the high volatile (boiling point 153-167 degrees C) components are the main constituents of the essential oils (61.69-63.81 mass%), followed by the low volatile (boiling point 252-288 degrees C) components (22.57-26.04 mass%), and the least present medium volatile (boiling point 173-212 degrees C) components (7.24-9.61 mass%). The variations in the mass content of the essential oil at various distillation rates showed clear general trends for all hydromodules (with exceptions at some components). With the increasing of distillation rate, mass% of high and medium volatile components decreased, while mass% of low volatile components increased. This is caused by higher extraction of low volatile components at high distillation rate, which resulted the increasing of their mass%. The variations in the mass composition of the essential oil at various hydromodules showed less expressive trends for all distillation rates. That means it has much less influence on the mass composition than the variation of distillation rate. Therefore, experiments at various distillation rates should be continued in combination with the fractionation of the essential oil by simultaneous hydrodistillation and rectification, including the effects of preparation procedures of juniper berries and defining of optimal energy consumption, i.e., optimal time period of hydrodistillation.
PB  - Savez hemijskih inženjera, Beograd
T2  - Hemijska industrija
T1  - Influence of hydrodistillation rate and hydromodule on chemical composition of juniperus communis l. Essential oil
EP  - 10
IS  - 1
SP  - 1
VL  - 71
DO  - 10.2298/HEMIND151119011P
ER  - 

@article{
author = "Pavićević, Vladimir and Radović, Marko N. and Milojević, Svetomir and Marković, Miljana S. and Ristić, Mihailo S. and Povrenović, Dragan",
year = "2017",
abstract = "Essential oils are aromatic, volatile, complex mixtures of various compounds, mainly hydrocarbons (monoterpene and sesquiterpene) and some oxygenated hydrocarbons. Juniper berry essential oil has wide application and high commercial value due to its considerable antimicrobial activities. It is used in medicine, food, cosmetic and pharmaceutical industry and veterinary medicine. Generally, it is obtained by hydrodistillation, technique for the extraction of substances which do not mix or mix very poorly with water and are unstable at their boiling temperatures. It provides high quality of essential oil and also represents a relatively simple, safe and environmentally friendly process. The variations in the chemical composition of the essential oil obtained from juniper berries at various distillation rates (3, 6 and 8 ml/min) and various mass ratio juniper berries-water (hydromodules -1:3, 1: 4 and 1: 5) are presented in this paper. It is important to emphasize that the variations made influence only in quantitative (mass%), but not in qualitative chemical composition (no differences, same 58 components were detected in all experiments). To reflect those effects, only 23 identified components with the content higher than 0.5 mass% were selected, constituted 95-96 mass% of the essential oils. The major constituents of the essential oils were monoterpenes (67.39-71.00 mass%), followed by sesquiterpenes (21.64-24.54 mass%), while the oxygenated monoterpene (1.54-2.42 mas.%) and oxygenated sesquiterpenes (0.89-1.46 mass%) were much less present. According to volatility, the high volatile (boiling point 153-167 degrees C) components are the main constituents of the essential oils (61.69-63.81 mass%), followed by the low volatile (boiling point 252-288 degrees C) components (22.57-26.04 mass%), and the least present medium volatile (boiling point 173-212 degrees C) components (7.24-9.61 mass%). The variations in the mass content of the essential oil at various distillation rates showed clear general trends for all hydromodules (with exceptions at some components). With the increasing of distillation rate, mass% of high and medium volatile components decreased, while mass% of low volatile components increased. This is caused by higher extraction of low volatile components at high distillation rate, which resulted the increasing of their mass%. The variations in the mass composition of the essential oil at various hydromodules showed less expressive trends for all distillation rates. That means it has much less influence on the mass composition than the variation of distillation rate. Therefore, experiments at various distillation rates should be continued in combination with the fractionation of the essential oil by simultaneous hydrodistillation and rectification, including the effects of preparation procedures of juniper berries and defining of optimal energy consumption, i.e., optimal time period of hydrodistillation.",
publisher = "Savez hemijskih inženjera, Beograd",
journal = "Hemijska industrija",
title = "Influence of hydrodistillation rate and hydromodule on chemical composition of juniperus communis l. Essential oil",
pages = "10-1",
number = "1",
volume = "71",
doi = "10.2298/HEMIND151119011P"
}

Pavićević, V., Radović, M. N., Milojević, S., Marković, M. S., Ristić, M. S.,& Povrenović, D.. (2017). Influence of hydrodistillation rate and hydromodule on chemical composition of juniperus communis l. Essential oil. in Hemijska industrija
Savez hemijskih inženjera, Beograd., 71(1), 1-10.
https://doi.org/10.2298/HEMIND151119011P

Pavićević V, Radović MN, Milojević S, Marković MS, Ristić MS, Povrenović D. Influence of hydrodistillation rate and hydromodule on chemical composition of juniperus communis l. Essential oil. in Hemijska industrija. 2017;71(1):1-10.
doi:10.2298/HEMIND151119011P .

Pavićević, Vladimir, Radović, Marko N., Milojević, Svetomir, Marković, Miljana S., Ristić, Mihailo S., Povrenović, Dragan, "Influence of hydrodistillation rate and hydromodule on chemical composition of juniperus communis l. Essential oil" in Hemijska industrija, 71, no. 1 (2017):1-10,
https://doi.org/10.2298/HEMIND151119011P . .

TY  - JOUR
AU  - Petrović, Nada V.
AU  - Petrović, Slobodan S.
AU  - Džamić, Ana M.
AU  - Ćirić, Ana D.
AU  - Ristić, Mihailo S.
AU  - Milovanović, Stoja
AU  - Petrović, Slobodan
PY  - 2016
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3394
AB  - The chemical composition, antimicrobial and antioxidant activity of Thymus praecox extracts obtained by fractional supercritical fluid extraction (SFE) with carbon dioxide were investigated. Properties of supercritical extracts and extracts obtained by Soxhiet extraction were compared. The chemical composition of extracts was determined using GC-FID and GC-MS analytical methods. The antimicrobial activity of extracts was evaluated against 16 pathogenic microorganisms using microdilution method. Antioxidant potential of extracts to neutralize DPPH radicals was also investigated. Investigated supercritical extracts showed better antimicrobial activity than commercial antibiotics (streptomycin and ampicillin) and commercial fungicides (bifonazol and ketoconazole) against all tested strains. For bacteria MIC and MBC were 38-200 mu g/m1 and 75-300 mu g/ml, respectively, while for fungi MIC and MFC were 17-150 mu g/ml and 35-300 mu g/ml, respectively.
PB  - Elsevier Science Bv, Amsterdam
T2  - Journal of Supercritical Fluids
T1  - Chemical composition, antioxidant and antimicrobial activity of Thymus praecox supercritical extracts
EP  - 125
SP  - 117
VL  - 110
DO  - 10.1016/j.supflu.2016.01.001
ER  - 

@article{
author = "Petrović, Nada V. and Petrović, Slobodan S. and Džamić, Ana M. and Ćirić, Ana D. and Ristić, Mihailo S. and Milovanović, Stoja and Petrović, Slobodan",
year = "2016",
abstract = "The chemical composition, antimicrobial and antioxidant activity of Thymus praecox extracts obtained by fractional supercritical fluid extraction (SFE) with carbon dioxide were investigated. Properties of supercritical extracts and extracts obtained by Soxhiet extraction were compared. The chemical composition of extracts was determined using GC-FID and GC-MS analytical methods. The antimicrobial activity of extracts was evaluated against 16 pathogenic microorganisms using microdilution method. Antioxidant potential of extracts to neutralize DPPH radicals was also investigated. Investigated supercritical extracts showed better antimicrobial activity than commercial antibiotics (streptomycin and ampicillin) and commercial fungicides (bifonazol and ketoconazole) against all tested strains. For bacteria MIC and MBC were 38-200 mu g/m1 and 75-300 mu g/ml, respectively, while for fungi MIC and MFC were 17-150 mu g/ml and 35-300 mu g/ml, respectively.",
publisher = "Elsevier Science Bv, Amsterdam",
journal = "Journal of Supercritical Fluids",
title = "Chemical composition, antioxidant and antimicrobial activity of Thymus praecox supercritical extracts",
pages = "125-117",
volume = "110",
doi = "10.1016/j.supflu.2016.01.001"
}

Petrović, N. V., Petrović, S. S., Džamić, A. M., Ćirić, A. D., Ristić, M. S., Milovanović, S.,& Petrović, S.. (2016). Chemical composition, antioxidant and antimicrobial activity of Thymus praecox supercritical extracts. in Journal of Supercritical Fluids
Elsevier Science Bv, Amsterdam., 110, 117-125.
https://doi.org/10.1016/j.supflu.2016.01.001

Petrović NV, Petrović SS, Džamić AM, Ćirić AD, Ristić MS, Milovanović S, Petrović S. Chemical composition, antioxidant and antimicrobial activity of Thymus praecox supercritical extracts. in Journal of Supercritical Fluids. 2016;110:117-125.
doi:10.1016/j.supflu.2016.01.001 .

Petrović, Nada V., Petrović, Slobodan S., Džamić, Ana M., Ćirić, Ana D., Ristić, Mihailo S., Milovanović, Stoja, Petrović, Slobodan, "Chemical composition, antioxidant and antimicrobial activity of Thymus praecox supercritical extracts" in Journal of Supercritical Fluids, 110 (2016):117-125,
https://doi.org/10.1016/j.supflu.2016.01.001 . .

TY  - JOUR
AU  - Pavićević, Vladimir
AU  - Marković, Miljana S.
AU  - Milojević, Svetomir
AU  - Ristić, Mihailo S.
AU  - Povrenović, Dragan
AU  - Veljković, Vlada B.
PY  - 2016
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3460
AB  - BACKGROUNDMicrowave-assisted hydrodistillation (MAHD) has widely been used to isolate essential oil from various plant materials, but it has not been applied yet to extract essential oil from juniper berries. The main goals of the present work were to establish a model describing the extraction kinetics and the chemical composition of the essential oil obtained. RESULTSA lower final essential oil yield from juniper berries was obtained by MAHD than by conventional hydrodistillation (HD). No significant differences in chemical compositions of the essential oils extracted by the two techniques were observed. The mechanism of both processes was the same and included fast (washing) and slow (diffusion) distillation of essential oil that occurred simultaneously. CONCLUSIONThe kinetic model involving simultaneous washing and diffusion of essential oil was verified for various plant materials (areal parts of savory and thyme, fennel seeds and juniper berries) for both MAHD and HD that indicated its general importance. For the first time, the kinetic models of MAHD and HD were compared. Knowledge of the juniper berry essential oil yield and the extraction kinetics is of importance from the technological and economics points of view, while the chemical composition determines its use.
PB  - Wiley, Hoboken
T2  - Journal of Chemical Technology and Biotechnology
T1  - Microwave-assisted hydrodistillation of juniper berry essential oil: kinetic modeling and chemical composition
EP  - 891
IS  - 4
SP  - 883
VL  - 91
DO  - 10.1002/jctb.4653
ER  - 

@article{
author = "Pavićević, Vladimir and Marković, Miljana S. and Milojević, Svetomir and Ristić, Mihailo S. and Povrenović, Dragan and Veljković, Vlada B.",
year = "2016",
abstract = "BACKGROUNDMicrowave-assisted hydrodistillation (MAHD) has widely been used to isolate essential oil from various plant materials, but it has not been applied yet to extract essential oil from juniper berries. The main goals of the present work were to establish a model describing the extraction kinetics and the chemical composition of the essential oil obtained. RESULTSA lower final essential oil yield from juniper berries was obtained by MAHD than by conventional hydrodistillation (HD). No significant differences in chemical compositions of the essential oils extracted by the two techniques were observed. The mechanism of both processes was the same and included fast (washing) and slow (diffusion) distillation of essential oil that occurred simultaneously. CONCLUSIONThe kinetic model involving simultaneous washing and diffusion of essential oil was verified for various plant materials (areal parts of savory and thyme, fennel seeds and juniper berries) for both MAHD and HD that indicated its general importance. For the first time, the kinetic models of MAHD and HD were compared. Knowledge of the juniper berry essential oil yield and the extraction kinetics is of importance from the technological and economics points of view, while the chemical composition determines its use.",
publisher = "Wiley, Hoboken",
journal = "Journal of Chemical Technology and Biotechnology",
title = "Microwave-assisted hydrodistillation of juniper berry essential oil: kinetic modeling and chemical composition",
pages = "891-883",
number = "4",
volume = "91",
doi = "10.1002/jctb.4653"
}

Pavićević, V., Marković, M. S., Milojević, S., Ristić, M. S., Povrenović, D.,& Veljković, V. B.. (2016). Microwave-assisted hydrodistillation of juniper berry essential oil: kinetic modeling and chemical composition. in Journal of Chemical Technology and Biotechnology
Wiley, Hoboken., 91(4), 883-891.
https://doi.org/10.1002/jctb.4653

Pavićević V, Marković MS, Milojević S, Ristić MS, Povrenović D, Veljković VB. Microwave-assisted hydrodistillation of juniper berry essential oil: kinetic modeling and chemical composition. in Journal of Chemical Technology and Biotechnology. 2016;91(4):883-891.
doi:10.1002/jctb.4653 .

Pavićević, Vladimir, Marković, Miljana S., Milojević, Svetomir, Ristić, Mihailo S., Povrenović, Dragan, Veljković, Vlada B., "Microwave-assisted hydrodistillation of juniper berry essential oil: kinetic modeling and chemical composition" in Journal of Chemical Technology and Biotechnology, 91, no. 4 (2016):883-891,
https://doi.org/10.1002/jctb.4653 . .

TY  - JOUR
AU  - Bogdanović, Aleksandra
AU  - Tadić, Vanja
AU  - Ristić, Mihailo S.
AU  - Petrović, Slobodan
AU  - Skala, Dejan
PY  - 2016
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3344
AB  - Supercritical CO2 (SC-CO2) extraction of fenugreek seeds (Trigonella foenum-graecum L, Fabaceae) was analyzed using different pressure and temperature (16.6-33.4 MPa and, 30-50 degrees C), which corresponded to SC-CO2 density between 779 and 957 kg/m(3). The yield of extract as well as its composition were determined and analyzed for different solvent consumption defined as mass of used CO2 for extraction per mass of dry fenugreek seeds. A central composite design (CCD) combined with response surface methodology (RSM) was used to study the best extraction conditions which determined that 27.0 MPa, 42.6 degrees C, and 24.6 gCO(2)/g(dm), were the optimal conditions for isolation of total extract. The calculated yield of extract at these conditions defined by SC-CO2 density of 890 kg/m3 could be 2.57% based on fenugreek seed. Moreover, the best extraction conditions for obtaining extract which contains the maximal amount of sterols, or maximal amount of vitamin E or vitamin D were also analyzed. These RSM optimizations showed that at slightly lower pressure (22.8-24.8 MPa), temperature (39.9-42.0 degrees C) and consumption of SC-CO2 (19.0-19.7 gCO(2)/g(dm)) is followed by smaller amount of isolated extract but with maximum content of sterols (16.28%), or vitamin E or vitamin D (1.44% and 0.71%, respectively) at these conditions. Calculation of molar solubility of total extract, and apparent solubility of sterols, vitamin E and D in SC-CO2 was performed at different pressure and temperature. They were correlated to density of SC-CO2, temperature at which extractions were performed and Hildebrand solubility parameter of solvent and solubility parameter of compounds which are the main constituents of extract. These calculations also show that the highest molar solubility of total extract and apparent molar solubility of its constituents could be obtained using optimal density of SC-CO2 (830-890 kg/m(3)) defined by corresponding values of temperature and pressure (310-320 K and 20-25 MPa).
PB  - Elsevier Science Bv, Amsterdam
T2  - Journal of Supercritical Fluids
T1  - Optimization of supercritical CO2 extraction of fenugreek seed (Trigonella foenum-graecum L.) and calculating of extracts solubility
EP  - 307
SP  - 297
VL  - 117
DO  - 10.1016/j.supflu.2016.07.010
ER  - 

@article{
author = "Bogdanović, Aleksandra and Tadić, Vanja and Ristić, Mihailo S. and Petrović, Slobodan and Skala, Dejan",
year = "2016",
abstract = "Supercritical CO2 (SC-CO2) extraction of fenugreek seeds (Trigonella foenum-graecum L, Fabaceae) was analyzed using different pressure and temperature (16.6-33.4 MPa and, 30-50 degrees C), which corresponded to SC-CO2 density between 779 and 957 kg/m(3). The yield of extract as well as its composition were determined and analyzed for different solvent consumption defined as mass of used CO2 for extraction per mass of dry fenugreek seeds. A central composite design (CCD) combined with response surface methodology (RSM) was used to study the best extraction conditions which determined that 27.0 MPa, 42.6 degrees C, and 24.6 gCO(2)/g(dm), were the optimal conditions for isolation of total extract. The calculated yield of extract at these conditions defined by SC-CO2 density of 890 kg/m3 could be 2.57% based on fenugreek seed. Moreover, the best extraction conditions for obtaining extract which contains the maximal amount of sterols, or maximal amount of vitamin E or vitamin D were also analyzed. These RSM optimizations showed that at slightly lower pressure (22.8-24.8 MPa), temperature (39.9-42.0 degrees C) and consumption of SC-CO2 (19.0-19.7 gCO(2)/g(dm)) is followed by smaller amount of isolated extract but with maximum content of sterols (16.28%), or vitamin E or vitamin D (1.44% and 0.71%, respectively) at these conditions. Calculation of molar solubility of total extract, and apparent solubility of sterols, vitamin E and D in SC-CO2 was performed at different pressure and temperature. They were correlated to density of SC-CO2, temperature at which extractions were performed and Hildebrand solubility parameter of solvent and solubility parameter of compounds which are the main constituents of extract. These calculations also show that the highest molar solubility of total extract and apparent molar solubility of its constituents could be obtained using optimal density of SC-CO2 (830-890 kg/m(3)) defined by corresponding values of temperature and pressure (310-320 K and 20-25 MPa).",
publisher = "Elsevier Science Bv, Amsterdam",
journal = "Journal of Supercritical Fluids",
title = "Optimization of supercritical CO2 extraction of fenugreek seed (Trigonella foenum-graecum L.) and calculating of extracts solubility",
pages = "307-297",
volume = "117",
doi = "10.1016/j.supflu.2016.07.010"
}

Bogdanović, A., Tadić, V., Ristić, M. S., Petrović, S.,& Skala, D.. (2016). Optimization of supercritical CO2 extraction of fenugreek seed (Trigonella foenum-graecum L.) and calculating of extracts solubility. in Journal of Supercritical Fluids
Elsevier Science Bv, Amsterdam., 117, 297-307.
https://doi.org/10.1016/j.supflu.2016.07.010

Bogdanović A, Tadić V, Ristić MS, Petrović S, Skala D. Optimization of supercritical CO2 extraction of fenugreek seed (Trigonella foenum-graecum L.) and calculating of extracts solubility. in Journal of Supercritical Fluids. 2016;117:297-307.
doi:10.1016/j.supflu.2016.07.010 .

Bogdanović, Aleksandra, Tadić, Vanja, Ristić, Mihailo S., Petrović, Slobodan, Skala, Dejan, "Optimization of supercritical CO2 extraction of fenugreek seed (Trigonella foenum-graecum L.) and calculating of extracts solubility" in Journal of Supercritical Fluids, 117 (2016):297-307,
https://doi.org/10.1016/j.supflu.2016.07.010 . .

TY  - JOUR
AU  - Petrović, Slobodan S.
AU  - Ristić, Mihailo S.
AU  - Petrović, Nada V.
AU  - Lazić, Miodrag L.
AU  - Francišković, Marina
AU  - Petrović, Slobodan
PY  - 2014
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/2631
AB  - Wild thyme (Thymus serpyllum L.) is a popular remedy regarding both tradetional and conventional medicine. It is used as the antiseptic, aromatic, expectorant, stomachic, antispasmodic, carminative and preservative substance. For the purpose of this paper, wild thyme essential oil was isolated from the dried herb T. serpyllum by hydrodistillation. Original semi-industrial distillation device SP-130 performing distillation by water and steam was used for the hydrodistillation of T. serpyllum essential oils. The temperature during the hydrodistillation in the device SP-130 ranged from 100-102 °C at atmospheric pressure, and the whole process lasted 5 hours. The isolated essential oil is a liquid of light yellow colour and the odour characteristic of the genus Thymus. Obtained yield of essential oil was 0.08 %, with 65 components identified in the tested essential oil. The most represented chemical groups are sesquiturpene hydrocarbons with 35.1%, and oxygenated sesquiturpenes with 34.8%. The main components of essential oil of T. serpyllum were: trans-nerolidol (24.2%), germacrene D (16.0%), thymol (7.3%), δ-cadinene (3.7%) and β-bisabolene (3.3%). The essential oil showed significantly better ability to neutralize DPPH free radicals (IC50 = 0.503 μL/mL) compared with synthetic antioxidants BHA and BHT. Synthetic chemical compounds such as BHA and BHT are used in food industry as antioxidants due to their ability to prolong the shelf-life of foodstuffs by protecting them against deterioration caused by oxidation, such as fat rancidity, colour changes, degradation of the flavor and loss of nutrient value. In recent years, there is a considerable interest in finding natural compounds that could replace sinthetic antioxidants because of adverse toxicological reports on many synthetic compounds. Lamiaceae herbs and their essential oils or extracts application has proven to be the effective preservation agents for the extension shelf-life of foodstuffs, indicating their potential use in food industry as functional ingredients and food additives. The antioxidant activity of extracts from some Lamiaceae herbs is comparable to that of the most common synthetic antioxidants BHT and BHA. Free radicals are a major cause of many degenerative diseases, such as atherosclerosis, cancer, cardiovascular diseases, inflammatory bowel diseases, skin aging, old age dementia and arthritis. Epidemiological data and randomized clinical trials provide sample indications that antioxidants play a fundamental role in the prevention of cancer and cardiovascular diseases. They act as scavengers of reactive oxygen species and metal chelators that protect human cells and reduce oxidative damages. Natural antioxidants are important in the food industry because they can have a double functionality, that is, they can be useful as a food preservation agents while providing important health benefits for humans by maintaining our health and preventing disease. This investigation showed that the essential oil of T. serpyllum can be an important source for the production and application in the food industry as nutritional supplements, functional food components or natural food antioxidants.
AB  - Cilj ovog rada bio je ispitivanje hemijskog sastava i antioksidativnog potencijala etarskog ulja majčine dušice (Thymus serpyllum L.). Etarsko ulje majčine dušice izolovano je iz osušene herbe T. serpyllum postupkom hidrodestilacije. Za hidrodestilaciju etarskog ulja T. serpyllum koriščen je originalni poluindustrijski destilacioni uređaj SP-130 koji radi na principu destilacije vodom i vodenom parom. Gasnohromatografskom analizom određene su najzastupljenije komponente kod etarskog ulja T. serpyllum: trans-nerolidol (24,2%), germakren D (16,0%), timol (7,3%), δ-kadinen (3,7%) i β-bisabolen (3,3%). Etarsko ulje je pokazalo značajno bolju sposobnost neutralizacije slobodnih DPPH radikala (IC50 = 0,503 μL/ml) u poređenju sa sintetskim antioksidansima BHA i BHT.
PB  - Association of Chemical Engineers of Serbia
T2  - Hemijska industrija
T1  - Chemical composition and antioxidative activity of essential oil of Thymus serpyllum L.
T1  - Hemijski sastav i antioksidativna aktivnost etarskog ulja Thymus serpyllum L.
EP  - 397
IS  - 3
SP  - 389
VL  - 68
DO  - 10.2298/HEMIND130513051P
ER  - 

@article{
author = "Petrović, Slobodan S. and Ristić, Mihailo S. and Petrović, Nada V. and Lazić, Miodrag L. and Francišković, Marina and Petrović, Slobodan",
year = "2014",
abstract = "Wild thyme (Thymus serpyllum L.) is a popular remedy regarding both tradetional and conventional medicine. It is used as the antiseptic, aromatic, expectorant, stomachic, antispasmodic, carminative and preservative substance. For the purpose of this paper, wild thyme essential oil was isolated from the dried herb T. serpyllum by hydrodistillation. Original semi-industrial distillation device SP-130 performing distillation by water and steam was used for the hydrodistillation of T. serpyllum essential oils. The temperature during the hydrodistillation in the device SP-130 ranged from 100-102 °C at atmospheric pressure, and the whole process lasted 5 hours. The isolated essential oil is a liquid of light yellow colour and the odour characteristic of the genus Thymus. Obtained yield of essential oil was 0.08 %, with 65 components identified in the tested essential oil. The most represented chemical groups are sesquiturpene hydrocarbons with 35.1%, and oxygenated sesquiturpenes with 34.8%. The main components of essential oil of T. serpyllum were: trans-nerolidol (24.2%), germacrene D (16.0%), thymol (7.3%), δ-cadinene (3.7%) and β-bisabolene (3.3%). The essential oil showed significantly better ability to neutralize DPPH free radicals (IC50 = 0.503 μL/mL) compared with synthetic antioxidants BHA and BHT. Synthetic chemical compounds such as BHA and BHT are used in food industry as antioxidants due to their ability to prolong the shelf-life of foodstuffs by protecting them against deterioration caused by oxidation, such as fat rancidity, colour changes, degradation of the flavor and loss of nutrient value. In recent years, there is a considerable interest in finding natural compounds that could replace sinthetic antioxidants because of adverse toxicological reports on many synthetic compounds. Lamiaceae herbs and their essential oils or extracts application has proven to be the effective preservation agents for the extension shelf-life of foodstuffs, indicating their potential use in food industry as functional ingredients and food additives. The antioxidant activity of extracts from some Lamiaceae herbs is comparable to that of the most common synthetic antioxidants BHT and BHA. Free radicals are a major cause of many degenerative diseases, such as atherosclerosis, cancer, cardiovascular diseases, inflammatory bowel diseases, skin aging, old age dementia and arthritis. Epidemiological data and randomized clinical trials provide sample indications that antioxidants play a fundamental role in the prevention of cancer and cardiovascular diseases. They act as scavengers of reactive oxygen species and metal chelators that protect human cells and reduce oxidative damages. Natural antioxidants are important in the food industry because they can have a double functionality, that is, they can be useful as a food preservation agents while providing important health benefits for humans by maintaining our health and preventing disease. This investigation showed that the essential oil of T. serpyllum can be an important source for the production and application in the food industry as nutritional supplements, functional food components or natural food antioxidants., Cilj ovog rada bio je ispitivanje hemijskog sastava i antioksidativnog potencijala etarskog ulja majčine dušice (Thymus serpyllum L.). Etarsko ulje majčine dušice izolovano je iz osušene herbe T. serpyllum postupkom hidrodestilacije. Za hidrodestilaciju etarskog ulja T. serpyllum koriščen je originalni poluindustrijski destilacioni uređaj SP-130 koji radi na principu destilacije vodom i vodenom parom. Gasnohromatografskom analizom određene su najzastupljenije komponente kod etarskog ulja T. serpyllum: trans-nerolidol (24,2%), germakren D (16,0%), timol (7,3%), δ-kadinen (3,7%) i β-bisabolen (3,3%). Etarsko ulje je pokazalo značajno bolju sposobnost neutralizacije slobodnih DPPH radikala (IC50 = 0,503 μL/ml) u poređenju sa sintetskim antioksidansima BHA i BHT.",
publisher = "Association of Chemical Engineers of Serbia",
journal = "Hemijska industrija",
title = "Chemical composition and antioxidative activity of essential oil of Thymus serpyllum L., Hemijski sastav i antioksidativna aktivnost etarskog ulja Thymus serpyllum L.",
pages = "397-389",
number = "3",
volume = "68",
doi = "10.2298/HEMIND130513051P"
}

Petrović, S. S., Ristić, M. S., Petrović, N. V., Lazić, M. L., Francišković, M.,& Petrović, S.. (2014). Chemical composition and antioxidative activity of essential oil of Thymus serpyllum L.. in Hemijska industrija
Association of Chemical Engineers of Serbia., 68(3), 389-397.
https://doi.org/10.2298/HEMIND130513051P

Petrović SS, Ristić MS, Petrović NV, Lazić ML, Francišković M, Petrović S. Chemical composition and antioxidative activity of essential oil of Thymus serpyllum L.. in Hemijska industrija. 2014;68(3):389-397.
doi:10.2298/HEMIND130513051P .

Petrović, Slobodan S., Ristić, Mihailo S., Petrović, Nada V., Lazić, Miodrag L., Francišković, Marina, Petrović, Slobodan, "Chemical composition and antioxidative activity of essential oil of Thymus serpyllum L." in Hemijska industrija, 68, no. 3 (2014):389-397,
https://doi.org/10.2298/HEMIND130513051P . .

TY  - JOUR
AU  - Ivanović, Jasna
AU  - Dimitrijević-Branković, Suzana
AU  - Mišić, Dušan
AU  - Ristić, Mihailo S.
AU  - Žižović, Irena
PY  - 2013
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/2507
AB  - For the first time, extracts from clove buds obtained by supercritical carbon dioxide extraction were screened for antioxidant and antibacterial activities. Additionally, antioxidant and antibacterial activities of extracts obtained by the supercritical extraction of the clove bud-oregano leaf mixtures were studied. Supercritical extract of pure clove had the highest eugenol (64%) and total phenolic content (530.56 mg GAE/g(extract)). All extracts had antioxidant activity comparable to synthetic antioxidants against 2,2-diphenyl-1-picrylhydrazyl (DPPH) radicals and formation of peroxides. Presence of 0.6% and 5% of oregano extract in the clove extracts obtained from the clove-oregano plant mixtures improved their antioxidant activity with respect to the extract from pure clove. Clove extract showed moderate antibacterial activities against selected Staphylococcus and Enterococcus bacterial strains. Presence of 50% of the oregano extract improved antibacterial activity of clove extract against all tested strains and resulted in a synergistic antibacterial activity against Methicillin-resistant Staphylococcus haemolyticus strain (MIC  lt = 1.25 mu g/mL). Study demonstrated great potential of supercritical clove extract as natural functional ingredient and the possibility of increasing its antioxidant and antibacterial efficiencies in order to apply lower concentrations and to reduce undesirable flavour notes and toxicological effects in final products.
PB  - Elsevier, Amsterdam
T2  - Journal of Functional Foods
T1  - Evaluation and improvement of antioxidant and antibacterial activities of supercritical extracts from clove buds
EP  - 423
IS  - 1
SP  - 416
VL  - 5
DO  - 10.1016/j.jff.2012.11.014
ER  - 

@article{
author = "Ivanović, Jasna and Dimitrijević-Branković, Suzana and Mišić, Dušan and Ristić, Mihailo S. and Žižović, Irena",
year = "2013",
abstract = "For the first time, extracts from clove buds obtained by supercritical carbon dioxide extraction were screened for antioxidant and antibacterial activities. Additionally, antioxidant and antibacterial activities of extracts obtained by the supercritical extraction of the clove bud-oregano leaf mixtures were studied. Supercritical extract of pure clove had the highest eugenol (64%) and total phenolic content (530.56 mg GAE/g(extract)). All extracts had antioxidant activity comparable to synthetic antioxidants against 2,2-diphenyl-1-picrylhydrazyl (DPPH) radicals and formation of peroxides. Presence of 0.6% and 5% of oregano extract in the clove extracts obtained from the clove-oregano plant mixtures improved their antioxidant activity with respect to the extract from pure clove. Clove extract showed moderate antibacterial activities against selected Staphylococcus and Enterococcus bacterial strains. Presence of 50% of the oregano extract improved antibacterial activity of clove extract against all tested strains and resulted in a synergistic antibacterial activity against Methicillin-resistant Staphylococcus haemolyticus strain (MIC  lt = 1.25 mu g/mL). Study demonstrated great potential of supercritical clove extract as natural functional ingredient and the possibility of increasing its antioxidant and antibacterial efficiencies in order to apply lower concentrations and to reduce undesirable flavour notes and toxicological effects in final products.",
publisher = "Elsevier, Amsterdam",
journal = "Journal of Functional Foods",
title = "Evaluation and improvement of antioxidant and antibacterial activities of supercritical extracts from clove buds",
pages = "423-416",
number = "1",
volume = "5",
doi = "10.1016/j.jff.2012.11.014"
}

Ivanović, J., Dimitrijević-Branković, S., Mišić, D., Ristić, M. S.,& Žižović, I.. (2013). Evaluation and improvement of antioxidant and antibacterial activities of supercritical extracts from clove buds. in Journal of Functional Foods
Elsevier, Amsterdam., 5(1), 416-423.
https://doi.org/10.1016/j.jff.2012.11.014

Ivanović J, Dimitrijević-Branković S, Mišić D, Ristić MS, Žižović I. Evaluation and improvement of antioxidant and antibacterial activities of supercritical extracts from clove buds. in Journal of Functional Foods. 2013;5(1):416-423.
doi:10.1016/j.jff.2012.11.014 .

Ivanović, Jasna, Dimitrijević-Branković, Suzana, Mišić, Dušan, Ristić, Mihailo S., Žižović, Irena, "Evaluation and improvement of antioxidant and antibacterial activities of supercritical extracts from clove buds" in Journal of Functional Foods, 5, no. 1 (2013):416-423,
https://doi.org/10.1016/j.jff.2012.11.014 . .

TY  - JOUR
AU  - Maksimović, Svetolik
AU  - Kesić, Željka
AU  - Lukić, Ivana
AU  - Milovanović, Stoja
AU  - Ristić, Mihailo S.
AU  - Skala, Dejan
PY  - 2013
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/2498
AB  - Yield and composition of curry flower (Helichrysum italicum) and sage leaves (Salvia officinalis) extract obtained by supercritical CO2 extraction (SFE) at 15 MPa and 40 degrees C were analyzed and compared to composition of curry flowers and sage essential oil isolated by hydrodistillation. Furthermore, the SFE performed using a mixture of curry flowers and sage plant and SFE of mixture of curry flowers and essential oil of sage were analyzed, too. It was shown that the average selectivity of monoterpenes and some individual sesquiterpenes and diterpenes present in pure sage or pure curry extract were significantly changed when mixture of these plants was used for SFE. The goal of SFE realized with mixture of curry flowers and sage essential oil was to explain effect of essential oil used as co-solvent changing the solubility of different compounds or characteristic group of terpenes in supercritical CO2. Increased extraction of heavier compounds from curry flower which is actually not present in pure essential oil of sage was also detected. The pseudo-kinetic model was proposed and corresponding parameters which define the rate of extraction were determined and compared to the parameters obtained according to Sovova's model usually used in literature for predicting yield of SFE from different plants.
PB  - Elsevier, Amsterdam
T2  - Journal of Supercritical Fluids
T1  - Supercritical fluid extraction of curry flowers, sage leaves, and their mixture
EP  - 12
SP  - 1
VL  - 84
DO  - 10.1016/j.supflu.2013.09.003
ER  - 

@article{
author = "Maksimović, Svetolik and Kesić, Željka and Lukić, Ivana and Milovanović, Stoja and Ristić, Mihailo S. and Skala, Dejan",
year = "2013",
abstract = "Yield and composition of curry flower (Helichrysum italicum) and sage leaves (Salvia officinalis) extract obtained by supercritical CO2 extraction (SFE) at 15 MPa and 40 degrees C were analyzed and compared to composition of curry flowers and sage essential oil isolated by hydrodistillation. Furthermore, the SFE performed using a mixture of curry flowers and sage plant and SFE of mixture of curry flowers and essential oil of sage were analyzed, too. It was shown that the average selectivity of monoterpenes and some individual sesquiterpenes and diterpenes present in pure sage or pure curry extract were significantly changed when mixture of these plants was used for SFE. The goal of SFE realized with mixture of curry flowers and sage essential oil was to explain effect of essential oil used as co-solvent changing the solubility of different compounds or characteristic group of terpenes in supercritical CO2. Increased extraction of heavier compounds from curry flower which is actually not present in pure essential oil of sage was also detected. The pseudo-kinetic model was proposed and corresponding parameters which define the rate of extraction were determined and compared to the parameters obtained according to Sovova's model usually used in literature for predicting yield of SFE from different plants.",
publisher = "Elsevier, Amsterdam",
journal = "Journal of Supercritical Fluids",
title = "Supercritical fluid extraction of curry flowers, sage leaves, and their mixture",
pages = "12-1",
volume = "84",
doi = "10.1016/j.supflu.2013.09.003"
}

Maksimović, S., Kesić, Ž., Lukić, I., Milovanović, S., Ristić, M. S.,& Skala, D.. (2013). Supercritical fluid extraction of curry flowers, sage leaves, and their mixture. in Journal of Supercritical Fluids
Elsevier, Amsterdam., 84, 1-12.
https://doi.org/10.1016/j.supflu.2013.09.003

Maksimović S, Kesić Ž, Lukić I, Milovanović S, Ristić MS, Skala D. Supercritical fluid extraction of curry flowers, sage leaves, and their mixture. in Journal of Supercritical Fluids. 2013;84:1-12.
doi:10.1016/j.supflu.2013.09.003 .

Maksimović, Svetolik, Kesić, Željka, Lukić, Ivana, Milovanović, Stoja, Ristić, Mihailo S., Skala, Dejan, "Supercritical fluid extraction of curry flowers, sage leaves, and their mixture" in Journal of Supercritical Fluids, 84 (2013):1-12,
https://doi.org/10.1016/j.supflu.2013.09.003 . .

TY  - JOUR
AU  - Ivanović, Jasna
AU  - Mišić, Dušan
AU  - Žižović, Irena
AU  - Ristić, Mihailo
PY  - 2012
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/5691
AB  - Antibacterial activity of thyme, rosemary and sage isolates obtained by supercritical fluid extraction and hydrodistillation was investigated on Geobacillus stearotermophillus, Bacillus cereus, Bacillus subtilis var. niger, Enterococcus faecium, Salmonella enteritidis and Escherichia coli strains. Bacillus species were the most susceptible to all tested isolates. The thyme isolates showed the strongest antibacterial activity against tested bacteria with MIC values of 40-640 mu g/ml, followed by rosemary (MIC = 320-1280 mu g/ml) and sage (MIC = 160-2560 mu g/ml) isolates. Therefore, the antibacterial activity of the most abundant components found in the thyme isolates, thymol, p-cymene and their mixture was investigated as well. The thyme isolates, especially supercritical extract, showed stronger antibacterial activity against Bacillus strains compared to the single components and their mixture, which indicated synergetic effect of the other components. Results of this study indicated thyme as a valuable source of natural antibacterial agents and supercritical fluid extraction as an efficient isolation method.
PB  - Elsevier Sci Ltd, Oxford
T2  - Food Control
T1  - In vitro control of multiplication of some food-associated bacteria by thyme, rosemary and sage isolates
EP  - 116
IS  - 1
SP  - 110
VL  - 25
DO  - 10.1016/j.foodcont.2011.10.019
ER  - 

@article{
author = "Ivanović, Jasna and Mišić, Dušan and Žižović, Irena and Ristić, Mihailo",
year = "2012",
abstract = "Antibacterial activity of thyme, rosemary and sage isolates obtained by supercritical fluid extraction and hydrodistillation was investigated on Geobacillus stearotermophillus, Bacillus cereus, Bacillus subtilis var. niger, Enterococcus faecium, Salmonella enteritidis and Escherichia coli strains. Bacillus species were the most susceptible to all tested isolates. The thyme isolates showed the strongest antibacterial activity against tested bacteria with MIC values of 40-640 mu g/ml, followed by rosemary (MIC = 320-1280 mu g/ml) and sage (MIC = 160-2560 mu g/ml) isolates. Therefore, the antibacterial activity of the most abundant components found in the thyme isolates, thymol, p-cymene and their mixture was investigated as well. The thyme isolates, especially supercritical extract, showed stronger antibacterial activity against Bacillus strains compared to the single components and their mixture, which indicated synergetic effect of the other components. Results of this study indicated thyme as a valuable source of natural antibacterial agents and supercritical fluid extraction as an efficient isolation method.",
publisher = "Elsevier Sci Ltd, Oxford",
journal = "Food Control",
title = "In vitro control of multiplication of some food-associated bacteria by thyme, rosemary and sage isolates",
pages = "116-110",
number = "1",
volume = "25",
doi = "10.1016/j.foodcont.2011.10.019"
}

Ivanović, J., Mišić, D., Žižović, I.,& Ristić, M.. (2012). In vitro control of multiplication of some food-associated bacteria by thyme, rosemary and sage isolates. in Food Control
Elsevier Sci Ltd, Oxford., 25(1), 110-116.
https://doi.org/10.1016/j.foodcont.2011.10.019

Ivanović J, Mišić D, Žižović I, Ristić M. In vitro control of multiplication of some food-associated bacteria by thyme, rosemary and sage isolates. in Food Control. 2012;25(1):110-116.
doi:10.1016/j.foodcont.2011.10.019 .

Ivanović, Jasna, Mišić, Dušan, Žižović, Irena, Ristić, Mihailo, "In vitro control of multiplication of some food-associated bacteria by thyme, rosemary and sage isolates" in Food Control, 25, no. 1 (2012):110-116,
https://doi.org/10.1016/j.foodcont.2011.10.019 . .

TY  - JOUR
AU  - Ivanović, Jasna
AU  - Žižović, Irena
AU  - Ristić, Mihailo S.
AU  - Stamenić, Marko
AU  - Skala, Dejan
PY  - 2011
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/1920
AB  - The goal of present work was to investigate and explain kinetics and mass transfer phenomena occurring during the SFE from the mixture of two plants with different initial composition. The extractions from pure clove, oregano and thyme as well as from clove/oregano (C/O) and clove/thyme (C/T) mixtures with various initial compositions of plant material were carried out using supercritical CO2 at 10 MPa and 40 degrees C. The results indicated that presence of light compounds in supercritical CO2 originated from the oregano leaves or thyme at the beginning of extraction process increases the extraction rate of compounds from clove bud. Only small added amounts of oregano or thyme to clove bud (C/O - 90:10%, w/w; or C/T - 84:16%, w/w) in the starting plant mixture had the same effect resulted in the similar and the highest increase of the extraction rate and had negligible influence on total extraction yield compared to extract isolated from pure clove. Different mathematical models were used for simulation of experimental data which showed that the highest increase of the solubility of extractable compounds in supercritical CO2 as well as the highest mass transfer rate in the solid phase during extractions existed during extraction from C/O (90:10, w/w) and C/T (84:16, w/w) mixtures. Decrease of SC CO2 consumption or shorter time of extraction necessary for achieving desired extract yield in the case of SFE of the clove buds could be important for industrial-scale application.
PB  - Elsevier, Amsterdam
T2  - Journal of Supercritical Fluids
T1  - The analysis of simultaneous clove/oregano and clove/thyme supercritical extraction
EP  - 991
IS  - 3
SP  - 983
VL  - 55
DO  - 10.1016/j.supflu.2010.09.012
ER  - 

@article{
author = "Ivanović, Jasna and Žižović, Irena and Ristić, Mihailo S. and Stamenić, Marko and Skala, Dejan",
year = "2011",
abstract = "The goal of present work was to investigate and explain kinetics and mass transfer phenomena occurring during the SFE from the mixture of two plants with different initial composition. The extractions from pure clove, oregano and thyme as well as from clove/oregano (C/O) and clove/thyme (C/T) mixtures with various initial compositions of plant material were carried out using supercritical CO2 at 10 MPa and 40 degrees C. The results indicated that presence of light compounds in supercritical CO2 originated from the oregano leaves or thyme at the beginning of extraction process increases the extraction rate of compounds from clove bud. Only small added amounts of oregano or thyme to clove bud (C/O - 90:10%, w/w; or C/T - 84:16%, w/w) in the starting plant mixture had the same effect resulted in the similar and the highest increase of the extraction rate and had negligible influence on total extraction yield compared to extract isolated from pure clove. Different mathematical models were used for simulation of experimental data which showed that the highest increase of the solubility of extractable compounds in supercritical CO2 as well as the highest mass transfer rate in the solid phase during extractions existed during extraction from C/O (90:10, w/w) and C/T (84:16, w/w) mixtures. Decrease of SC CO2 consumption or shorter time of extraction necessary for achieving desired extract yield in the case of SFE of the clove buds could be important for industrial-scale application.",
publisher = "Elsevier, Amsterdam",
journal = "Journal of Supercritical Fluids",
title = "The analysis of simultaneous clove/oregano and clove/thyme supercritical extraction",
pages = "991-983",
number = "3",
volume = "55",
doi = "10.1016/j.supflu.2010.09.012"
}

Ivanović, J., Žižović, I., Ristić, M. S., Stamenić, M.,& Skala, D.. (2011). The analysis of simultaneous clove/oregano and clove/thyme supercritical extraction. in Journal of Supercritical Fluids
Elsevier, Amsterdam., 55(3), 983-991.
https://doi.org/10.1016/j.supflu.2010.09.012

Ivanović J, Žižović I, Ristić MS, Stamenić M, Skala D. The analysis of simultaneous clove/oregano and clove/thyme supercritical extraction. in Journal of Supercritical Fluids. 2011;55(3):983-991.
doi:10.1016/j.supflu.2010.09.012 .

Ivanović, Jasna, Žižović, Irena, Ristić, Mihailo S., Stamenić, Marko, Skala, Dejan, "The analysis of simultaneous clove/oregano and clove/thyme supercritical extraction" in Journal of Supercritical Fluids, 55, no. 3 (2011):983-991,
https://doi.org/10.1016/j.supflu.2010.09.012 . .

TY  - JOUR
AU  - Glišić, Sandra
AU  - Ristić, Mihailo S.
AU  - Skala, Dejan
PY  - 2011
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/1933
AB  - A wide spectrum of phytochemicals could be isolated from sage (Salvia officinalis L) using different extraction or distillation technique: the supercritical fluid extraction (SFE), the volatiles compounds (monoterpenes and sesquiterpenes) isolation using hydrodistillation or higher molecular compounds with Soxhlet extraction or ultrasound-assisted extraction. The combination of ultrasound-assisted extraction followed by re-extraction of obtained extract with supercritical CO2 was performed in this study. The goal of performed investigation was to concentrate diterpenes present in sage extract which are generally considered to be responsible for antioxidant activity of extracted compounds. The fractionation using the supercritical CO2, and different combination of the ultrasound-assisted solvent extractions (water-ethanol mixture or only water) followed by supercritical CO2 re-extraction of obtained extract or treated plant material were analyzed and compared. Based on the results of these investigations it could be proposed the best extraction procedure: the ultrasound pretreatment of plant material with distilled water and re-extraction of plant material (residue) using supercritical CO2. That procedure gives two valuable products: the ultrasound extract which is rich in sugars and possess the immunomodulatory activity and supercritical extract which is rich in diterpenes and sesquiterpenes.
PB  - Elsevier Science Bv, Amsterdam
T2  - Ultrasonics Sonochemistry
T1  - The combined extraction of sage (Salvia officinalis L.): Ultrasound followed by supercritical CO2 extraction
EP  - 326
IS  - 1
SP  - 318
VL  - 18
DO  - 10.1016/j.ultsonch.2010.06.011
ER  - 

@article{
author = "Glišić, Sandra and Ristić, Mihailo S. and Skala, Dejan",
year = "2011",
abstract = "A wide spectrum of phytochemicals could be isolated from sage (Salvia officinalis L) using different extraction or distillation technique: the supercritical fluid extraction (SFE), the volatiles compounds (monoterpenes and sesquiterpenes) isolation using hydrodistillation or higher molecular compounds with Soxhlet extraction or ultrasound-assisted extraction. The combination of ultrasound-assisted extraction followed by re-extraction of obtained extract with supercritical CO2 was performed in this study. The goal of performed investigation was to concentrate diterpenes present in sage extract which are generally considered to be responsible for antioxidant activity of extracted compounds. The fractionation using the supercritical CO2, and different combination of the ultrasound-assisted solvent extractions (water-ethanol mixture or only water) followed by supercritical CO2 re-extraction of obtained extract or treated plant material were analyzed and compared. Based on the results of these investigations it could be proposed the best extraction procedure: the ultrasound pretreatment of plant material with distilled water and re-extraction of plant material (residue) using supercritical CO2. That procedure gives two valuable products: the ultrasound extract which is rich in sugars and possess the immunomodulatory activity and supercritical extract which is rich in diterpenes and sesquiterpenes.",
publisher = "Elsevier Science Bv, Amsterdam",
journal = "Ultrasonics Sonochemistry",
title = "The combined extraction of sage (Salvia officinalis L.): Ultrasound followed by supercritical CO2 extraction",
pages = "326-318",
number = "1",
volume = "18",
doi = "10.1016/j.ultsonch.2010.06.011"
}

Glišić, S., Ristić, M. S.,& Skala, D.. (2011). The combined extraction of sage (Salvia officinalis L.): Ultrasound followed by supercritical CO2 extraction. in Ultrasonics Sonochemistry
Elsevier Science Bv, Amsterdam., 18(1), 318-326.
https://doi.org/10.1016/j.ultsonch.2010.06.011

Glišić S, Ristić MS, Skala D. The combined extraction of sage (Salvia officinalis L.): Ultrasound followed by supercritical CO2 extraction. in Ultrasonics Sonochemistry. 2011;18(1):318-326.
doi:10.1016/j.ultsonch.2010.06.011 .

Glišić, Sandra, Ristić, Mihailo S., Skala, Dejan, "The combined extraction of sage (Salvia officinalis L.): Ultrasound followed by supercritical CO2 extraction" in Ultrasonics Sonochemistry, 18, no. 1 (2011):318-326,
https://doi.org/10.1016/j.ultsonch.2010.06.011 . .

TY  - JOUR
AU  - Ivanović, Jasna
AU  - Mišić, Dušan
AU  - Ristić, Mihailo
AU  - Pešić, Olivera
AU  - Žižović, Irena
PY  - 2010
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/5614
AB  - The present study deals with the supercritical carbon dioxide (SC-CO2) extraction and hydrodistillation (HD) of dried bay leaves (Laurus nobilis L.). The chemical composition and antibacterial activity of the SC-CO2 extract and essential oil (EO) from dried leaves of bay were compared to each other and literature data. Qualitative and quantitative analyzes of the SC-CO2 extract and EO were performed using GC-FID and GC-MS analytical methods. A significant difference in the chemical composition of the SC-CO2 extract and EO was observed. The EO comprised high contents of monoterpenes and their oxygenated derivates (98.4 %), principally 1,8-cineole (33.4 %), linalool (16.0 %) and α-terpinyl acetate (13.8 %), sabinene (6.91 %) and methyl eugenol (5.32 %). The SC-CO2 extract comprised twice less monoterpenes and their oxygenated derivates (43.89 %), together with sesquiterpenes (12.43 %), diterpenes (1.33 %) and esters (31.13 %). The major components were methyl linoleate (16.18 %), α-terpinyl acetate (12.88 %), linalool (9.00 %), methyl eugenol (8.67 %), methyl arachidonate (6.28 %) and eugenol (6.14 %). An investigation of the antibacterial activity of bay SC-CO2 extract and EO was completed on different Staphylococcus strains using the broth macrodilution method. Staphylococcus intermedius strains were the most susceptible to both the SC-CO2 extract and EO (MIC = 640 μg/ml).
AB  - U radu je ispitana nadkritična ekstrakcija i hidrodestilacija osušenih listova lovora (Laurus nobilis L.). Prikazana je uporedna analiza hemijskog sastava i antibakterijske aktivnosti nadkritičnog ekstrakta i etarskog ulja kao i poređenje istih sa literaturnim podacima. Za kvalitativnu i kvantitativnu analizu hemijskog sastava nadkritičnog ekstrakta i etarskog ulja korišćene su GC-FID i GC-MS analitičke metode. Hemijski sastav nadkritičnog ekstrakta i ulja lovora bio je veoma različit. Najzastupljenije komponente u etarskom ulju bili su monoterpeni i njihovi kiseonični derivati (98,4 %), pre svega 1,8-cineol (33,4 %), linalool (16,0 %), α-terpinil-acetat (13,8 %), sabinen (6,91 %) i metil-eugenol (5,32 %). Nadkritični ekstrakt lovora sadržao je dva puta manju količinu monoterpena i njihovih kiseoničnih derivata u odnosu na etarsko ulje (43,89 %) pored seskviterpena (12,43 %), diterpena (1,33 %) i estra (31,13 %). U nadkritičnom ekstraktu najzastupljenije komponente bili su metil-linoleat (16,18 %), α-terpinil-acetat (12,88 %), linalool (9,00 %), metil-eugenol (8,67 %), metil-arahidonat (6,28 %) i eugenol (6,14 %). Antibakterijsko delovanje nadkritičnog ekstrakta i etarskog ulja lovora ispitivano je na sojevima Staphylococcus primenom makrodilucione metode u bujonu. Sojevi Staphylococcus intermedius bili su najosetljiviji na nadkritični ekstrakt i etarsko ulje lovora pri čemu su vrednosti MIC bile 640 μg/ml.
PB  - Srpsko hemijsko društvo, Beograd
T2  - Journal of the Serbian Chemical Society
T1  - Supercritical CO2 extract and essential oil of bay (Laurus nobilis L.): Chemical composition and antibacterial activity
T1  - Natkritični ekstrakt i etarsko ulje lovora (Laurus nobilis L.) - hemijski sastav i antibakterijska aktivnost
EP  - 404
IS  - 3
SP  - 395
VL  - 75
DO  - 10.2298/JSC090303003I
ER  - 

@article{
author = "Ivanović, Jasna and Mišić, Dušan and Ristić, Mihailo and Pešić, Olivera and Žižović, Irena",
year = "2010",
abstract = "The present study deals with the supercritical carbon dioxide (SC-CO2) extraction and hydrodistillation (HD) of dried bay leaves (Laurus nobilis L.). The chemical composition and antibacterial activity of the SC-CO2 extract and essential oil (EO) from dried leaves of bay were compared to each other and literature data. Qualitative and quantitative analyzes of the SC-CO2 extract and EO were performed using GC-FID and GC-MS analytical methods. A significant difference in the chemical composition of the SC-CO2 extract and EO was observed. The EO comprised high contents of monoterpenes and their oxygenated derivates (98.4 %), principally 1,8-cineole (33.4 %), linalool (16.0 %) and α-terpinyl acetate (13.8 %), sabinene (6.91 %) and methyl eugenol (5.32 %). The SC-CO2 extract comprised twice less monoterpenes and their oxygenated derivates (43.89 %), together with sesquiterpenes (12.43 %), diterpenes (1.33 %) and esters (31.13 %). The major components were methyl linoleate (16.18 %), α-terpinyl acetate (12.88 %), linalool (9.00 %), methyl eugenol (8.67 %), methyl arachidonate (6.28 %) and eugenol (6.14 %). An investigation of the antibacterial activity of bay SC-CO2 extract and EO was completed on different Staphylococcus strains using the broth macrodilution method. Staphylococcus intermedius strains were the most susceptible to both the SC-CO2 extract and EO (MIC = 640 μg/ml)., U radu je ispitana nadkritična ekstrakcija i hidrodestilacija osušenih listova lovora (Laurus nobilis L.). Prikazana je uporedna analiza hemijskog sastava i antibakterijske aktivnosti nadkritičnog ekstrakta i etarskog ulja kao i poređenje istih sa literaturnim podacima. Za kvalitativnu i kvantitativnu analizu hemijskog sastava nadkritičnog ekstrakta i etarskog ulja korišćene su GC-FID i GC-MS analitičke metode. Hemijski sastav nadkritičnog ekstrakta i ulja lovora bio je veoma različit. Najzastupljenije komponente u etarskom ulju bili su monoterpeni i njihovi kiseonični derivati (98,4 %), pre svega 1,8-cineol (33,4 %), linalool (16,0 %), α-terpinil-acetat (13,8 %), sabinen (6,91 %) i metil-eugenol (5,32 %). Nadkritični ekstrakt lovora sadržao je dva puta manju količinu monoterpena i njihovih kiseoničnih derivata u odnosu na etarsko ulje (43,89 %) pored seskviterpena (12,43 %), diterpena (1,33 %) i estra (31,13 %). U nadkritičnom ekstraktu najzastupljenije komponente bili su metil-linoleat (16,18 %), α-terpinil-acetat (12,88 %), linalool (9,00 %), metil-eugenol (8,67 %), metil-arahidonat (6,28 %) i eugenol (6,14 %). Antibakterijsko delovanje nadkritičnog ekstrakta i etarskog ulja lovora ispitivano je na sojevima Staphylococcus primenom makrodilucione metode u bujonu. Sojevi Staphylococcus intermedius bili su najosetljiviji na nadkritični ekstrakt i etarsko ulje lovora pri čemu su vrednosti MIC bile 640 μg/ml.",
publisher = "Srpsko hemijsko društvo, Beograd",
journal = "Journal of the Serbian Chemical Society",
title = "Supercritical CO2 extract and essential oil of bay (Laurus nobilis L.): Chemical composition and antibacterial activity, Natkritični ekstrakt i etarsko ulje lovora (Laurus nobilis L.) - hemijski sastav i antibakterijska aktivnost",
pages = "404-395",
number = "3",
volume = "75",
doi = "10.2298/JSC090303003I"
}

Ivanović, J., Mišić, D., Ristić, M., Pešić, O.,& Žižović, I.. (2010). Supercritical CO2 extract and essential oil of bay (Laurus nobilis L.): Chemical composition and antibacterial activity. in Journal of the Serbian Chemical Society
Srpsko hemijsko društvo, Beograd., 75(3), 395-404.
https://doi.org/10.2298/JSC090303003I

Ivanović J, Mišić D, Ristić M, Pešić O, Žižović I. Supercritical CO2 extract and essential oil of bay (Laurus nobilis L.): Chemical composition and antibacterial activity. in Journal of the Serbian Chemical Society. 2010;75(3):395-404.
doi:10.2298/JSC090303003I .

Ivanović, Jasna, Mišić, Dušan, Ristić, Mihailo, Pešić, Olivera, Žižović, Irena, "Supercritical CO2 extract and essential oil of bay (Laurus nobilis L.): Chemical composition and antibacterial activity" in Journal of the Serbian Chemical Society, 75, no. 3 (2010):395-404,
https://doi.org/10.2298/JSC090303003I . .

TY  - JOUR
AU  - Glišić, Sandra
AU  - Ivanović, Jasna
AU  - Ristić, Mihailo S.
AU  - Skala, Dejan
PY  - 2010
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/1676
AB  - The supercritical carbon dioxide (SFE) extraction of Dalmatian sage (Salvia officinalis L) was investigated and compared to extraction performed by Soxhlet ethanol-water (70:30) mixture extraction (SE) and hydrodistillation (HD). The supercritical extraction allowed isolation of wide spectrum of phytochemicals, while other applied methods were limited to either volatiles (HD) or high molecular compounds isolation (SE). The kinetics of the supercritical extraction and fractionation within the pressure range of 10-30 MPa at 50 degrees C were also analyzed as well as the chemical compositions of total extract and partial or differential fractions isolated at different CO2. consumption. Volatile fraction could be isolated at low pressure and low CO2 consumption, whereby the pressures between 10 and 15 MPa followed by increased CO2 consumption were favourable for obtaining desired selectivity of diterpenes which contain compounds with expressed antioxidative characteristics.
PB  - Elsevier Science Bv, Amsterdam
T2  - Journal of Supercritical Fluids
T1  - Extraction of sage (Salvia officinalis L.) by supercritical CO2: Kinetic data, chemical composition and selectivity of diterpenes
EP  - 70
IS  - 1
SP  - 62
VL  - 52
DO  - 10.1016/j.supflu.2009.11.009
ER  - 

@article{
author = "Glišić, Sandra and Ivanović, Jasna and Ristić, Mihailo S. and Skala, Dejan",
year = "2010",
abstract = "The supercritical carbon dioxide (SFE) extraction of Dalmatian sage (Salvia officinalis L) was investigated and compared to extraction performed by Soxhlet ethanol-water (70:30) mixture extraction (SE) and hydrodistillation (HD). The supercritical extraction allowed isolation of wide spectrum of phytochemicals, while other applied methods were limited to either volatiles (HD) or high molecular compounds isolation (SE). The kinetics of the supercritical extraction and fractionation within the pressure range of 10-30 MPa at 50 degrees C were also analyzed as well as the chemical compositions of total extract and partial or differential fractions isolated at different CO2. consumption. Volatile fraction could be isolated at low pressure and low CO2 consumption, whereby the pressures between 10 and 15 MPa followed by increased CO2 consumption were favourable for obtaining desired selectivity of diterpenes which contain compounds with expressed antioxidative characteristics.",
publisher = "Elsevier Science Bv, Amsterdam",
journal = "Journal of Supercritical Fluids",
title = "Extraction of sage (Salvia officinalis L.) by supercritical CO2: Kinetic data, chemical composition and selectivity of diterpenes",
pages = "70-62",
number = "1",
volume = "52",
doi = "10.1016/j.supflu.2009.11.009"
}

Glišić, S., Ivanović, J., Ristić, M. S.,& Skala, D.. (2010). Extraction of sage (Salvia officinalis L.) by supercritical CO2: Kinetic data, chemical composition and selectivity of diterpenes. in Journal of Supercritical Fluids
Elsevier Science Bv, Amsterdam., 52(1), 62-70.
https://doi.org/10.1016/j.supflu.2009.11.009

Glišić S, Ivanović J, Ristić MS, Skala D. Extraction of sage (Salvia officinalis L.) by supercritical CO2: Kinetic data, chemical composition and selectivity of diterpenes. in Journal of Supercritical Fluids. 2010;52(1):62-70.
doi:10.1016/j.supflu.2009.11.009 .

Glišić, Sandra, Ivanović, Jasna, Ristić, Mihailo S., Skala, Dejan, "Extraction of sage (Salvia officinalis L.) by supercritical CO2: Kinetic data, chemical composition and selectivity of diterpenes" in Journal of Supercritical Fluids, 52, no. 1 (2010):62-70,
https://doi.org/10.1016/j.supflu.2009.11.009 . .

TY  - JOUR
AU  - Janjić, Svjetlana
AU  - Kostić, Mirjana
AU  - Vucinić, Verica
AU  - Dimitrijević, Suzana
AU  - Mihajlovski, Katarina
AU  - Ristić, Mihailo S.
AU  - Škundrić, Petar
PY  - 2009
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/1426
AB  - The possibilities of obtaining biologically active cell ulose-chitosan fibers were examined. An effective two-stage method was developed. The first stage involves the formation of dialdehyde cellulose by the potassium periodate oxidation of lyocell fibers, which is able to form Schiff's base with chitosan. In the second stage, chitosan-coated lyocell fibers were prepared by subsequent treatment of oxidized lyocell fibers with a solution of chitosan in aqueous acetic acid. The impact of this two-stage protocol on the chemical and physical properties of lyocell fibers was evaluated by determining carbonyl group content, fineness and tensile strength of fibers, as well as chitosan content in the composite cell ulose-chitosan fibers. Antibacterial activity of the chitosan-coated lyocell fibers against different pathogenens: Staphylococcus aureus and Escherichia coli, was confirmed in vitro experiments.
PB  - Elsevier Sci Ltd, Oxford
T2  - Carbohydrate Polymers
T1  - Biologically active fibers based on chitosan-coated lyocell fibers
EP  - 246
IS  - 2
SP  - 240
VL  - 78
DO  - 10.1016/j.carbpol.2009.03.033
ER  - 

@article{
author = "Janjić, Svjetlana and Kostić, Mirjana and Vucinić, Verica and Dimitrijević, Suzana and Mihajlovski, Katarina and Ristić, Mihailo S. and Škundrić, Petar",
year = "2009",
abstract = "The possibilities of obtaining biologically active cell ulose-chitosan fibers were examined. An effective two-stage method was developed. The first stage involves the formation of dialdehyde cellulose by the potassium periodate oxidation of lyocell fibers, which is able to form Schiff's base with chitosan. In the second stage, chitosan-coated lyocell fibers were prepared by subsequent treatment of oxidized lyocell fibers with a solution of chitosan in aqueous acetic acid. The impact of this two-stage protocol on the chemical and physical properties of lyocell fibers was evaluated by determining carbonyl group content, fineness and tensile strength of fibers, as well as chitosan content in the composite cell ulose-chitosan fibers. Antibacterial activity of the chitosan-coated lyocell fibers against different pathogenens: Staphylococcus aureus and Escherichia coli, was confirmed in vitro experiments.",
publisher = "Elsevier Sci Ltd, Oxford",
journal = "Carbohydrate Polymers",
title = "Biologically active fibers based on chitosan-coated lyocell fibers",
pages = "246-240",
number = "2",
volume = "78",
doi = "10.1016/j.carbpol.2009.03.033"
}

Janjić, S., Kostić, M., Vucinić, V., Dimitrijević, S., Mihajlovski, K., Ristić, M. S.,& Škundrić, P.. (2009). Biologically active fibers based on chitosan-coated lyocell fibers. in Carbohydrate Polymers
Elsevier Sci Ltd, Oxford., 78(2), 240-246.
https://doi.org/10.1016/j.carbpol.2009.03.033

Janjić S, Kostić M, Vucinić V, Dimitrijević S, Mihajlovski K, Ristić MS, Škundrić P. Biologically active fibers based on chitosan-coated lyocell fibers. in Carbohydrate Polymers. 2009;78(2):240-246.
doi:10.1016/j.carbpol.2009.03.033 .

Janjić, Svjetlana, Kostić, Mirjana, Vucinić, Verica, Dimitrijević, Suzana, Mihajlovski, Katarina, Ristić, Mihailo S., Škundrić, Petar, "Biologically active fibers based on chitosan-coated lyocell fibers" in Carbohydrate Polymers, 78, no. 2 (2009):240-246,
https://doi.org/10.1016/j.carbpol.2009.03.033 . .

TY  - JOUR
AU  - Mišić, Dušan
AU  - Žižović, Irena
AU  - Stamenić, Marko
AU  - Ašanin, Ružica
AU  - Ristić, Mihailo S.
AU  - Petrović, Slobodan
AU  - Skala, Dejan
PY  - 2008
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/1225
PB  - Elsevier, Amsterdam
T2  - Biochemical Engineering Journal
T1  - Antimicrobial activity of celery fruit isolates and SFE process modeling
EP  - 152
IS  - 2
SP  - 148
VL  - 42
DO  - 10.1016/j.bej.2008.06.008
ER  - 

@article{
author = "Mišić, Dušan and Žižović, Irena and Stamenić, Marko and Ašanin, Ružica and Ristić, Mihailo S. and Petrović, Slobodan and Skala, Dejan",
year = "2008",
publisher = "Elsevier, Amsterdam",
journal = "Biochemical Engineering Journal",
title = "Antimicrobial activity of celery fruit isolates and SFE process modeling",
pages = "152-148",
number = "2",
volume = "42",
doi = "10.1016/j.bej.2008.06.008"
}

Mišić, D., Žižović, I., Stamenić, M., Ašanin, R., Ristić, M. S., Petrović, S.,& Skala, D.. (2008). Antimicrobial activity of celery fruit isolates and SFE process modeling. in Biochemical Engineering Journal
Elsevier, Amsterdam., 42(2), 148-152.
https://doi.org/10.1016/j.bej.2008.06.008

Mišić D, Žižović I, Stamenić M, Ašanin R, Ristić MS, Petrović S, Skala D. Antimicrobial activity of celery fruit isolates and SFE process modeling. in Biochemical Engineering Journal. 2008;42(2):148-152.
doi:10.1016/j.bej.2008.06.008 .

Mišić, Dušan, Žižović, Irena, Stamenić, Marko, Ašanin, Ružica, Ristić, Mihailo S., Petrović, Slobodan, Skala, Dejan, "Antimicrobial activity of celery fruit isolates and SFE process modeling" in Biochemical Engineering Journal, 42, no. 2 (2008):148-152,
https://doi.org/10.1016/j.bej.2008.06.008 . .

TY  - JOUR
AU  - Žižović, Irena
AU  - Stamenić, Marko
AU  - Ivanović, Jasna
AU  - Orlović, Aleksandar
AU  - Ristić, Mihailo S.
AU  - Đorđević, Sofija
AU  - Petrović, Slobodan
AU  - Skala, Dejan
PY  - 2007
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/1136
AB  - Supercritical carbon dioxide extraction of sesquiterpenes from valerian root was investigated. Extractions from cultivar Arterner zuctung and two wild grown valerian subspecies were performed. The influence of extraction conditions on extraction yield and chemical composition of obtained extracts was investigated at temperatures from 40 degrees C to 50 degrees C and pressures from 10 MPa to 20 MPa. Chemical composition of obtained extracts was analyzed by GC/FID and GC/MS methods. The influence of particle size on extraction process was investigated at 40 degrees C and 10 MPa. The major constituents of supercritical extracts were valerianol, valerenal, bornyl acetate and kessanyl acetate. Optimal extraction conditions for the cyclopentanoid sesquiterepenes isolation, referred to the content of cyclopentanoid sesquiterpenes in extract, were found to be 50 degrees C and 15 MPa. Extract obtained from the cultivar was characterized by the higher content of cyclopentanoid sesquiterpenes, as well as valerenal comparing to extracts from wild grown species. At 40 degrees C and 20 MPa 19.6% of cyclopentanoid sequiterpenes isolated with methanol can be extracted. At 40 degrees C and 10 MPa, 17.4% of cyclopentanoid sequiterpenes isolated with methanol can be extracted. However, the extract obtained with methanol was characterized by the high content (42.51 %) of unwanted isovaleric as well as by the lower content of cyclopentanoid sequiterpenes than the extracts obtained with supercritical carbon dioxide. The process of supercritical extraction was influenced by particle size. In order to simulate the process, mathematical model on the secretory structure scale was derived. Results of the model showed good agreement with the experimental data.
PB  - Elsevier Science Bv, Amsterdam
T2  - Journal of Supercritical Fluids
T1  - Supercritical carbon dioxide extraction of sesquiterpenes from valerian root
EP  - 258
IS  - 2
SP  - 249
VL  - 43
DO  - 10.1016/j.supflu.2007.05.007
ER  - 

@article{
author = "Žižović, Irena and Stamenić, Marko and Ivanović, Jasna and Orlović, Aleksandar and Ristić, Mihailo S. and Đorđević, Sofija and Petrović, Slobodan and Skala, Dejan",
year = "2007",
abstract = "Supercritical carbon dioxide extraction of sesquiterpenes from valerian root was investigated. Extractions from cultivar Arterner zuctung and two wild grown valerian subspecies were performed. The influence of extraction conditions on extraction yield and chemical composition of obtained extracts was investigated at temperatures from 40 degrees C to 50 degrees C and pressures from 10 MPa to 20 MPa. Chemical composition of obtained extracts was analyzed by GC/FID and GC/MS methods. The influence of particle size on extraction process was investigated at 40 degrees C and 10 MPa. The major constituents of supercritical extracts were valerianol, valerenal, bornyl acetate and kessanyl acetate. Optimal extraction conditions for the cyclopentanoid sesquiterepenes isolation, referred to the content of cyclopentanoid sesquiterpenes in extract, were found to be 50 degrees C and 15 MPa. Extract obtained from the cultivar was characterized by the higher content of cyclopentanoid sesquiterpenes, as well as valerenal comparing to extracts from wild grown species. At 40 degrees C and 20 MPa 19.6% of cyclopentanoid sequiterpenes isolated with methanol can be extracted. At 40 degrees C and 10 MPa, 17.4% of cyclopentanoid sequiterpenes isolated with methanol can be extracted. However, the extract obtained with methanol was characterized by the high content (42.51 %) of unwanted isovaleric as well as by the lower content of cyclopentanoid sequiterpenes than the extracts obtained with supercritical carbon dioxide. The process of supercritical extraction was influenced by particle size. In order to simulate the process, mathematical model on the secretory structure scale was derived. Results of the model showed good agreement with the experimental data.",
publisher = "Elsevier Science Bv, Amsterdam",
journal = "Journal of Supercritical Fluids",
title = "Supercritical carbon dioxide extraction of sesquiterpenes from valerian root",
pages = "258-249",
number = "2",
volume = "43",
doi = "10.1016/j.supflu.2007.05.007"
}

Žižović, I., Stamenić, M., Ivanović, J., Orlović, A., Ristić, M. S., Đorđević, S., Petrović, S.,& Skala, D.. (2007). Supercritical carbon dioxide extraction of sesquiterpenes from valerian root. in Journal of Supercritical Fluids
Elsevier Science Bv, Amsterdam., 43(2), 249-258.
https://doi.org/10.1016/j.supflu.2007.05.007

Žižović I, Stamenić M, Ivanović J, Orlović A, Ristić MS, Đorđević S, Petrović S, Skala D. Supercritical carbon dioxide extraction of sesquiterpenes from valerian root. in Journal of Supercritical Fluids. 2007;43(2):249-258.
doi:10.1016/j.supflu.2007.05.007 .

Žižović, Irena, Stamenić, Marko, Ivanović, Jasna, Orlović, Aleksandar, Ristić, Mihailo S., Đorđević, Sofija, Petrović, Slobodan, Skala, Dejan, "Supercritical carbon dioxide extraction of sesquiterpenes from valerian root" in Journal of Supercritical Fluids, 43, no. 2 (2007):249-258,
https://doi.org/10.1016/j.supflu.2007.05.007 . .

TY  - JOUR
AU  - Aničić, Nada V.
AU  - Dimitrijević, Suzana
AU  - Ristić, Mihailo S.
AU  - Petrović, Slobodan S.
AU  - Petrović, Slobodan
PY  - 2005
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/764
AB  - The antimicrobial activity of the essential oil of Melissa officinalis was investigated in this paper. The essential oil was obtained by the principle of water and steam and analyzed by GC and GC-MS using FID and MSD. The main components of the oil of Melissa officinalis were geranial (17.30%), neral (14.70%) and citronellal (10.70%). The antimicrobial properties were tested against the following bacterial species: B subtilis, B.cereus Bifidobacterium sp., Corynobacterium sp., E. coli, Klebsiella sp., L. acidophilus, L. fermentum, L. plantarum, L. rhamnosus, Listeria monocytogenes, P. vulgaris, P. aerugenosa, S. enteritidis, Shigella sp., S. aureus, and fungi Candida albicans, Alternarija sp. and Aspergillus niger. The diffusion technique was used for testing: the antimicrobial activity, and the MIC was determined by the broth dilution method. The essential oil of M. officinalis showed high antimicrobial activity.
AB  - U radu je ispitivana antimikrobna aktivnost etarskog ulja matičnjaka (Melissa officinalis) izolovanog destilacijom vodom i vodenom parom, pomoću uređaja SP-250. GC i GC-MS analizom određene su najzastupljenije komponente kod etarskog ulja M. officinalis, a za ispitivanje biološke aktivnosti korišćeni su različite bakterije, kvasac Candida albicans, i plesni. Primenjena je metoda difuzije u bunarčićima ili aromatogram, kojom su određene zone inhibicije i zone smanjenog rasta. Nakon toga primenjivan je bujon dilucioni postupak za određivanje minimalne inhibitorne koncentracije (MIC). Etarsko ulje M. officinalis pokazalo je jako antimikrobno dejstvo.
PB  - Association of Chemical Engineers of Serbia
T2  - Hemijska industrija
T1  - Amtimicrobial activity of essential oil of Melissa officinalis L, Lamiaceae
T1  - Antimikrobna aktivnost etarskog ulja Melissa officinalis L, Lamiaceae
EP  - 247
IS  - 9-10
SP  - 243
VL  - 59
DO  - 10.2298/HEMIND0510243A
ER  - 

@article{
author = "Aničić, Nada V. and Dimitrijević, Suzana and Ristić, Mihailo S. and Petrović, Slobodan S. and Petrović, Slobodan",
year = "2005",
abstract = "The antimicrobial activity of the essential oil of Melissa officinalis was investigated in this paper. The essential oil was obtained by the principle of water and steam and analyzed by GC and GC-MS using FID and MSD. The main components of the oil of Melissa officinalis were geranial (17.30%), neral (14.70%) and citronellal (10.70%). The antimicrobial properties were tested against the following bacterial species: B subtilis, B.cereus Bifidobacterium sp., Corynobacterium sp., E. coli, Klebsiella sp., L. acidophilus, L. fermentum, L. plantarum, L. rhamnosus, Listeria monocytogenes, P. vulgaris, P. aerugenosa, S. enteritidis, Shigella sp., S. aureus, and fungi Candida albicans, Alternarija sp. and Aspergillus niger. The diffusion technique was used for testing: the antimicrobial activity, and the MIC was determined by the broth dilution method. The essential oil of M. officinalis showed high antimicrobial activity., U radu je ispitivana antimikrobna aktivnost etarskog ulja matičnjaka (Melissa officinalis) izolovanog destilacijom vodom i vodenom parom, pomoću uređaja SP-250. GC i GC-MS analizom određene su najzastupljenije komponente kod etarskog ulja M. officinalis, a za ispitivanje biološke aktivnosti korišćeni su različite bakterije, kvasac Candida albicans, i plesni. Primenjena je metoda difuzije u bunarčićima ili aromatogram, kojom su određene zone inhibicije i zone smanjenog rasta. Nakon toga primenjivan je bujon dilucioni postupak za određivanje minimalne inhibitorne koncentracije (MIC). Etarsko ulje M. officinalis pokazalo je jako antimikrobno dejstvo.",
publisher = "Association of Chemical Engineers of Serbia",
journal = "Hemijska industrija",
title = "Amtimicrobial activity of essential oil of Melissa officinalis L, Lamiaceae, Antimikrobna aktivnost etarskog ulja Melissa officinalis L, Lamiaceae",
pages = "247-243",
number = "9-10",
volume = "59",
doi = "10.2298/HEMIND0510243A"
}

Aničić, N. V., Dimitrijević, S., Ristić, M. S., Petrović, S. S.,& Petrović, S.. (2005). Amtimicrobial activity of essential oil of Melissa officinalis L, Lamiaceae. in Hemijska industrija
Association of Chemical Engineers of Serbia., 59(9-10), 243-247.
https://doi.org/10.2298/HEMIND0510243A

Aničić NV, Dimitrijević S, Ristić MS, Petrović SS, Petrović S. Amtimicrobial activity of essential oil of Melissa officinalis L, Lamiaceae. in Hemijska industrija. 2005;59(9-10):243-247.
doi:10.2298/HEMIND0510243A .

Aničić, Nada V., Dimitrijević, Suzana, Ristić, Mihailo S., Petrović, Slobodan S., Petrović, Slobodan, "Amtimicrobial activity of essential oil of Melissa officinalis L, Lamiaceae" in Hemijska industrija, 59, no. 9-10 (2005):243-247,
https://doi.org/10.2298/HEMIND0510243A . .

TY  - JOUR
AU  - Aničić, Nada V.
AU  - Dimitrijević, Suzana
AU  - Ristić, Mihailo S.
AU  - Petrović, Slobodan
PY  - 2005
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/766
AB  - The antimicrobial activity of the essential oil of Melissa officinal is was investigated in this paper. The essential oil was obtained by the principle of water and steam and analyzed by GC and GC-MS using FID and MSD. The main components of the oil of Melissa officinal is were geranial (17.30%), neral (14.70%) and citronellal (10.70%). The antimicrobial properties were tested against the follovving bacterial species: B subtilis, B.cereus Bifidobacterium sp., Corynobacterium sp., E. coli, Klebsiella sp., L. acidophilus, L. fermentum, L. plantarum, L. rhamnosus, Listeria monocytogenes, P. vulgaris, P. aerugenosa, S. enteritidis, Shigella sp., S. aureus, and fungi Candida albicans, Alternarija sp. and Aspergillus niger. The diffusion technique was used for testing: the antimicrobial activity and the MIC was determined by the broth dilution method. The essential oil of M. officinal is showed high antimicrobial activity.
AB  - U radu je ispitivana antimikrobna aktivnost etarskog ulja matičnjaka (Melissa officinalis) izolovanog destilacijom vodom i vodenom parom, pomoću uređaja SP-250, GC i GC-MS analizom određene su najzastupljenije komponente kod etarskog ulja M. officinalis, a za ispitivanje biološke aktivnosti korišćene su različite bakterije, kvasac Candida albicans, i plesni. Primenjena je metoda difuzije u bunarčićima ili aromatogram, kojom su određene zone inhibicije i zone smanjenog rasta. Nakon toga primenjivan je bujon dilucioni postupak za određivanje minimalne inhibitorne koncentracije (MIC). Etarsko ulje M. officinalis pokazalo je jako antimikrobno dejstvo.
PB  - Univerzitet u Nišu - Tehnološki fakultet, Leskovac
T2  - Zbornik radova Tehnološkog fakulteta, Leskovac
T1  - Amtimicrobial activity of essential oil of Melissa officinalis L., Lamiaceae
T1  - Antimikrobna aktivnost etarskog ulja Melissa officinalis L., Lamiaceae
EP  - 258
IS  - 14
SP  - 247
DO  - 10.1021/jf030698a
ER  - 

@article{
author = "Aničić, Nada V. and Dimitrijević, Suzana and Ristić, Mihailo S. and Petrović, Slobodan",
year = "2005",
abstract = "The antimicrobial activity of the essential oil of Melissa officinal is was investigated in this paper. The essential oil was obtained by the principle of water and steam and analyzed by GC and GC-MS using FID and MSD. The main components of the oil of Melissa officinal is were geranial (17.30%), neral (14.70%) and citronellal (10.70%). The antimicrobial properties were tested against the follovving bacterial species: B subtilis, B.cereus Bifidobacterium sp., Corynobacterium sp., E. coli, Klebsiella sp., L. acidophilus, L. fermentum, L. plantarum, L. rhamnosus, Listeria monocytogenes, P. vulgaris, P. aerugenosa, S. enteritidis, Shigella sp., S. aureus, and fungi Candida albicans, Alternarija sp. and Aspergillus niger. The diffusion technique was used for testing: the antimicrobial activity and the MIC was determined by the broth dilution method. The essential oil of M. officinal is showed high antimicrobial activity., U radu je ispitivana antimikrobna aktivnost etarskog ulja matičnjaka (Melissa officinalis) izolovanog destilacijom vodom i vodenom parom, pomoću uređaja SP-250, GC i GC-MS analizom određene su najzastupljenije komponente kod etarskog ulja M. officinalis, a za ispitivanje biološke aktivnosti korišćene su različite bakterije, kvasac Candida albicans, i plesni. Primenjena je metoda difuzije u bunarčićima ili aromatogram, kojom su određene zone inhibicije i zone smanjenog rasta. Nakon toga primenjivan je bujon dilucioni postupak za određivanje minimalne inhibitorne koncentracije (MIC). Etarsko ulje M. officinalis pokazalo je jako antimikrobno dejstvo.",
publisher = "Univerzitet u Nišu - Tehnološki fakultet, Leskovac",
journal = "Zbornik radova Tehnološkog fakulteta, Leskovac",
title = "Amtimicrobial activity of essential oil of Melissa officinalis L., Lamiaceae, Antimikrobna aktivnost etarskog ulja Melissa officinalis L., Lamiaceae",
pages = "258-247",
number = "14",
doi = "10.1021/jf030698a"
}

Aničić, N. V., Dimitrijević, S., Ristić, M. S.,& Petrović, S.. (2005). Amtimicrobial activity of essential oil of Melissa officinalis L., Lamiaceae. in Zbornik radova Tehnološkog fakulteta, Leskovac
Univerzitet u Nišu - Tehnološki fakultet, Leskovac.(14), 247-258.
https://doi.org/10.1021/jf030698a

Aničić NV, Dimitrijević S, Ristić MS, Petrović S. Amtimicrobial activity of essential oil of Melissa officinalis L., Lamiaceae. in Zbornik radova Tehnološkog fakulteta, Leskovac. 2005;(14):247-258.
doi:10.1021/jf030698a .

Aničić, Nada V., Dimitrijević, Suzana, Ristić, Mihailo S., Petrović, Slobodan, "Amtimicrobial activity of essential oil of Melissa officinalis L., Lamiaceae" in Zbornik radova Tehnološkog fakulteta, Leskovac, no. 14 (2005):247-258,
https://doi.org/10.1021/jf030698a . .

TY  - JOUR
AU  - Grujić-Jovanović, Slavica
AU  - Ristić, Mihailo S.
AU  - Petrović, Slobodan
AU  - Petrović, S.S.
AU  - Marin, Petar D.
AU  - Petković, Branimir
PY  - 2002
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/460
PB  - Univerzitet u Nišu - Tehnološki fakultet, Leskovac
T2  - Zbornik radova Tehnološkog fakulteta, Leskovac
T1  - Diterpeni roda stachys l. - potencijalni izvor bioaktivnih komponenata
EP  - 82
IS  - 12
SP  - 79
UR  - https://hdl.handle.net/21.15107/rcub_technorep_460
ER  - 

@article{
author = "Grujić-Jovanović, Slavica and Ristić, Mihailo S. and Petrović, Slobodan and Petrović, S.S. and Marin, Petar D. and Petković, Branimir",
year = "2002",
publisher = "Univerzitet u Nišu - Tehnološki fakultet, Leskovac",
journal = "Zbornik radova Tehnološkog fakulteta, Leskovac",
title = "Diterpeni roda stachys l. - potencijalni izvor bioaktivnih komponenata",
pages = "82-79",
number = "12",
url = "https://hdl.handle.net/21.15107/rcub_technorep_460"
}

Grujić-Jovanović, S., Ristić, M. S., Petrović, S., Petrović, S.S., Marin, P. D.,& Petković, B.. (2002). Diterpeni roda stachys l. - potencijalni izvor bioaktivnih komponenata. in Zbornik radova Tehnološkog fakulteta, Leskovac
Univerzitet u Nišu - Tehnološki fakultet, Leskovac.(12), 79-82.
https://hdl.handle.net/21.15107/rcub_technorep_460

Grujić-Jovanović S, Ristić MS, Petrović S, Petrović S, Marin PD, Petković B. Diterpeni roda stachys l. - potencijalni izvor bioaktivnih komponenata. in Zbornik radova Tehnološkog fakulteta, Leskovac. 2002;(12):79-82.
https://hdl.handle.net/21.15107/rcub_technorep_460 .

Grujić-Jovanović, Slavica, Ristić, Mihailo S., Petrović, Slobodan, Petrović, S.S., Marin, Petar D., Petković, Branimir, "Diterpeni roda stachys l. - potencijalni izvor bioaktivnih komponenata" in Zbornik radova Tehnološkog fakulteta, Leskovac, no. 12 (2002):79-82,
https://hdl.handle.net/21.15107/rcub_technorep_460 .

TY  - JOUR
AU  - Grujić-Jovanović, Slavica
AU  - Ristić, Mihailo S.
AU  - Petrović, Slobodan
AU  - Petrović, S.S.
AU  - Marin, Petar D.
AU  - Petković, Branimir
PY  - 2002
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/469
PB  - Univerzitet u Nišu - Tehnološki fakultet, Leskovac
T2  - Zbornik radova Tehnološkog fakulteta, Leskovac
T1  - Dobijanje etarskog ulja stachys plumosa gris. (Lamiaceae) korišćenjem sp-130/250 uređaja za destilaciju
EP  - 71
IS  - 12
SP  - 66
UR  - https://hdl.handle.net/21.15107/rcub_technorep_469
ER  - 

@article{
author = "Grujić-Jovanović, Slavica and Ristić, Mihailo S. and Petrović, Slobodan and Petrović, S.S. and Marin, Petar D. and Petković, Branimir",
year = "2002",
publisher = "Univerzitet u Nišu - Tehnološki fakultet, Leskovac",
journal = "Zbornik radova Tehnološkog fakulteta, Leskovac",
title = "Dobijanje etarskog ulja stachys plumosa gris. (Lamiaceae) korišćenjem sp-130/250 uređaja za destilaciju",
pages = "71-66",
number = "12",
url = "https://hdl.handle.net/21.15107/rcub_technorep_469"
}

Grujić-Jovanović, S., Ristić, M. S., Petrović, S., Petrović, S.S., Marin, P. D.,& Petković, B.. (2002). Dobijanje etarskog ulja stachys plumosa gris. (Lamiaceae) korišćenjem sp-130/250 uređaja za destilaciju. in Zbornik radova Tehnološkog fakulteta, Leskovac
Univerzitet u Nišu - Tehnološki fakultet, Leskovac.(12), 66-71.
https://hdl.handle.net/21.15107/rcub_technorep_469

Grujić-Jovanović S, Ristić MS, Petrović S, Petrović S, Marin PD, Petković B. Dobijanje etarskog ulja stachys plumosa gris. (Lamiaceae) korišćenjem sp-130/250 uređaja za destilaciju. in Zbornik radova Tehnološkog fakulteta, Leskovac. 2002;(12):66-71.
https://hdl.handle.net/21.15107/rcub_technorep_469 .

Grujić-Jovanović, Slavica, Ristić, Mihailo S., Petrović, Slobodan, Petrović, S.S., Marin, Petar D., Petković, Branimir, "Dobijanje etarskog ulja stachys plumosa gris. (Lamiaceae) korišćenjem sp-130/250 uređaja za destilaciju" in Zbornik radova Tehnološkog fakulteta, Leskovac, no. 12 (2002):66-71,
https://hdl.handle.net/21.15107/rcub_technorep_469 .

TY  - JOUR
AU  - Grujić-Jovanović, Slavica
AU  - Ristić, Mihailo S.
AU  - Petrović, Slobodan S.
AU  - Petrović, Slobodan
AU  - Marin, Petar D.
AU  - Petković, Branimir
PY  - 2000
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/333
AB  - The volatile constituents of the aerial parts of Stachys plumosa Griseb. isolated by hydrodistillation, were analysed by GC and GC/MS. The essential oil was composed of 105 components. The main components were β-pinene (19.7%), α-pinene (16.9%), dehydroabietane (11.9%), thunbergole (7.7%) and myrtenal (4.1%). The essential oil of S. plumosa contained many unidentified diterpenes.
AB  - U okviru istraživanja sadržaja i sastava etarskih ulja kod vrsta podfamilije Lamioideae, analizirano je etarsko ulje Stachys plumosa Griseb. Konstatovano je prisustvo 105 komponenata. Glavne komponente su: β-pinen (19,7%), α-pinen (16,9 %), dehidroabietan (11,9%), tanbergol (7,7%) i mirtenal (4,1%). Nisu identifikovane sve diterpenske komponente prisustne u uzorku.
PB  - Institute for Medicinal Plants Research "Dr. Josif Pancic"
T2  - Lekovite sirovine
T1  - Essential oil of Stachys plumosa Griseb. (Lamiaceae)
T1  - Sastav etarskog ulja Stachys plumosa Griseb. (Lamiaceae)
EP  - 19
IS  - 20
SP  - 13
UR  - https://hdl.handle.net/21.15107/rcub_technorep_333
ER  - 

@article{
author = "Grujić-Jovanović, Slavica and Ristić, Mihailo S. and Petrović, Slobodan S. and Petrović, Slobodan and Marin, Petar D. and Petković, Branimir",
year = "2000",
abstract = "The volatile constituents of the aerial parts of Stachys plumosa Griseb. isolated by hydrodistillation, were analysed by GC and GC/MS. The essential oil was composed of 105 components. The main components were β-pinene (19.7%), α-pinene (16.9%), dehydroabietane (11.9%), thunbergole (7.7%) and myrtenal (4.1%). The essential oil of S. plumosa contained many unidentified diterpenes., U okviru istraživanja sadržaja i sastava etarskih ulja kod vrsta podfamilije Lamioideae, analizirano je etarsko ulje Stachys plumosa Griseb. Konstatovano je prisustvo 105 komponenata. Glavne komponente su: β-pinen (19,7%), α-pinen (16,9 %), dehidroabietan (11,9%), tanbergol (7,7%) i mirtenal (4,1%). Nisu identifikovane sve diterpenske komponente prisustne u uzorku.",
publisher = "Institute for Medicinal Plants Research "Dr. Josif Pancic"",
journal = "Lekovite sirovine",
title = "Essential oil of Stachys plumosa Griseb. (Lamiaceae), Sastav etarskog ulja Stachys plumosa Griseb. (Lamiaceae)",
pages = "19-13",
number = "20",
url = "https://hdl.handle.net/21.15107/rcub_technorep_333"
}

Grujić-Jovanović, S., Ristić, M. S., Petrović, S. S., Petrović, S., Marin, P. D.,& Petković, B.. (2000). Essential oil of Stachys plumosa Griseb. (Lamiaceae). in Lekovite sirovine
Institute for Medicinal Plants Research "Dr. Josif Pancic".(20), 13-19.
https://hdl.handle.net/21.15107/rcub_technorep_333

Grujić-Jovanović S, Ristić MS, Petrović SS, Petrović S, Marin PD, Petković B. Essential oil of Stachys plumosa Griseb. (Lamiaceae). in Lekovite sirovine. 2000;(20):13-19.
https://hdl.handle.net/21.15107/rcub_technorep_333 .

Grujić-Jovanović, Slavica, Ristić, Mihailo S., Petrović, Slobodan S., Petrović, Slobodan, Marin, Petar D., Petković, Branimir, "Essential oil of Stachys plumosa Griseb. (Lamiaceae)" in Lekovite sirovine, no. 20 (2000):13-19,
https://hdl.handle.net/21.15107/rcub_technorep_333 .