Šavikin, Katarina

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  • Šavikin, Katarina (3)
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Author's Bibliography

Characterization of lyophilized alginate beads with Rosa canina L extract

Jovanović, Aleksandra A.; Balanč, Bojana; Đorđević, Verica; Živković, Jelena; Šavikin, Katarina; Nedović, Viktor; Bugarski, Branko

(Serbian Nutrition Society, 2021)

TY  - CONF
AU  - Jovanović, Aleksandra A.
AU  - Balanč, Bojana
AU  - Đorđević, Verica
AU  - Živković, Jelena
AU  - Šavikin, Katarina
AU  - Nedović, Viktor
AU  - Bugarski, Branko
PY  - 2021
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/6440
AB  - The aim of the present study was the characterization of lyophilized alginate beads with
Rosa canina extract via determination of encapsulation efficiency, total polyphenol and
flavonoid contents, antioxidant capacity, particle size, sphericity factor and polyphenol release in distilled water medium. Electrostatic extrusion process was carried out to obtain calcium-alginate beads with encapsulated R. canina extract, which further lyophilized in freeze
dryer at -75°C and pressure of 0.011 mbar for 24 h and at -65°C and pressure of 0.054 mbar
for 1 h. The total polyphenol content was evaluated spectrophotometrically using modified
Folin-Ciocalteu method, whereas total flavonoid content was determined using colorimetric assay; antioxidant capacity was analyzed in ABTS and DPPH assays. Total polyphenol
and flavonoid contents in lyophilized R. canina extract loaded beads were 68.9±0.4 mg gallic
acid equivalents/g of lyophilized beads and 37.1±3.8 mg catechin equivalents/g, respectively. Thus, determined encapsulation efficiency of polyphenols was 55.1±0.3 %. In ABTS assay,
antioxidant activity of lyophilized extract loaded beads was 10.7±0.1 mg Trolox/g, whereas
in DPPH assay, IC50 of lyophilized beads was 4.11±0.02 mg/mL. The size of the lyophilized
R. canina extract encapsulated particles with extract was 460.7±47.7 µm and sphericity factor was 0.12±0.08. In distilled water as a medium, most of polyphenols of lyophilized R.
canina extract loaded beads were released in the first 30 min, and the maximum release plateau was reached at 90 min. Lyophilized R. canina extract loaded alginate beads developed
in this study have potential to be used in food, pharmacological and cosmetic industries,
with the aim to improve functionality, bioavailability and stability of the products.
PB  - Serbian Nutrition Society
C3  - 14th Congress of Nutrition Belgrade, Serbia
T1  - Characterization of lyophilized alginate beads with Rosa canina L extract
EP  - 83
UR  - https://hdl.handle.net/21.15107/rcub_technorep_6440
ER  - 
@conference{
author = "Jovanović, Aleksandra A. and Balanč, Bojana and Đorđević, Verica and Živković, Jelena and Šavikin, Katarina and Nedović, Viktor and Bugarski, Branko",
year = "2021",
abstract = "The aim of the present study was the characterization of lyophilized alginate beads with
Rosa canina extract via determination of encapsulation efficiency, total polyphenol and
flavonoid contents, antioxidant capacity, particle size, sphericity factor and polyphenol release in distilled water medium. Electrostatic extrusion process was carried out to obtain calcium-alginate beads with encapsulated R. canina extract, which further lyophilized in freeze
dryer at -75°C and pressure of 0.011 mbar for 24 h and at -65°C and pressure of 0.054 mbar
for 1 h. The total polyphenol content was evaluated spectrophotometrically using modified
Folin-Ciocalteu method, whereas total flavonoid content was determined using colorimetric assay; antioxidant capacity was analyzed in ABTS and DPPH assays. Total polyphenol
and flavonoid contents in lyophilized R. canina extract loaded beads were 68.9±0.4 mg gallic
acid equivalents/g of lyophilized beads and 37.1±3.8 mg catechin equivalents/g, respectively. Thus, determined encapsulation efficiency of polyphenols was 55.1±0.3 %. In ABTS assay,
antioxidant activity of lyophilized extract loaded beads was 10.7±0.1 mg Trolox/g, whereas
in DPPH assay, IC50 of lyophilized beads was 4.11±0.02 mg/mL. The size of the lyophilized
R. canina extract encapsulated particles with extract was 460.7±47.7 µm and sphericity factor was 0.12±0.08. In distilled water as a medium, most of polyphenols of lyophilized R.
canina extract loaded beads were released in the first 30 min, and the maximum release plateau was reached at 90 min. Lyophilized R. canina extract loaded alginate beads developed
in this study have potential to be used in food, pharmacological and cosmetic industries,
with the aim to improve functionality, bioavailability and stability of the products.",
publisher = "Serbian Nutrition Society",
journal = "14th Congress of Nutrition Belgrade, Serbia",
title = "Characterization of lyophilized alginate beads with Rosa canina L extract",
pages = "83",
url = "https://hdl.handle.net/21.15107/rcub_technorep_6440"
}
Jovanović, A. A., Balanč, B., Đorđević, V., Živković, J., Šavikin, K., Nedović, V.,& Bugarski, B.. (2021). Characterization of lyophilized alginate beads with Rosa canina L extract. in 14th Congress of Nutrition Belgrade, Serbia
Serbian Nutrition Society..
https://hdl.handle.net/21.15107/rcub_technorep_6440
Jovanović AA, Balanč B, Đorđević V, Živković J, Šavikin K, Nedović V, Bugarski B. Characterization of lyophilized alginate beads with Rosa canina L extract. in 14th Congress of Nutrition Belgrade, Serbia. 2021;:null-83.
https://hdl.handle.net/21.15107/rcub_technorep_6440 .
Jovanović, Aleksandra A., Balanč, Bojana, Đorđević, Verica, Živković, Jelena, Šavikin, Katarina, Nedović, Viktor, Bugarski, Branko, "Characterization of lyophilized alginate beads with Rosa canina L extract" in 14th Congress of Nutrition Belgrade, Serbia (2021),
https://hdl.handle.net/21.15107/rcub_technorep_6440 .

Alginate-based encapsulation of polyphenols from Rosa canina L. extract

Jovanović, Aleksandra A.; Balanč, Bojana; Šavikin, Katarina; Živković, Jelena; Đorđević, Verica; Bugarski, Branko

(Faculty of Technology, Zvornik, 2021)

TY  - CONF
AU  - Jovanović, Aleksandra A.
AU  - Balanč, Bojana
AU  - Šavikin, Katarina
AU  - Živković, Jelena
AU  - Đorđević, Verica
AU  - Bugarski, Branko
PY  - 2021
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/6442
AB  - Rosa canina L. (Rosaceae) is frequently employed in traditional medicine, due to its diuretic,
anti-inflammatory, anti-allergic, antioxidant and analgesic effects. It is rich in various bioactive
compounds, including polyphenols, carotenoids, ascorbic acid, mineral elements and fatty acids.
Microencapsulation tehnique is a promising tool for improving R. canina polyphenols'
functionality, stability and bioavailability. Еlectrostatic extrusion process was carried out to
obtain calcium-alginate beads with encapsulated R. canina extract. In pure extract, total
polyphenol content was 103.8±1.9 mg GAE/g, whereas the concentration of flavonoids was
64.2±2.40 mg CE/g. Furthermore, polyphenol and flavonoid contents in extract loaded hydrogel
beads were 4.68±0.12 mg GAE/g and 2.93±0.23 mg CE/g, respectively. Thus, determined
encapsulation efficiency was 45.04±1.15%. In ABTS test, antioxidant activity of pure extract and
extract loaded hydrogel beads was 15.30±2.10 and 2.93±0.23 mg Trolox/g, respectively. In
DPPH test, IC50 of pure extract and extract loaded hydrogel beads was 1.07±0.01 and
29.32±2.15 mg/mL, respectively. The size of the produced R. canina extract encapsulated
hydrogel particles was 550.30±34.56 µm. In distilled water as a medium, most of polyphenols
were released relatively rapidly from alginate beads (in the first 20 min), and the maximum
release plateau was reached at 60 min. This study demonstrates the potential of using alginate
for encapsulation of R. canina polyphenols, with the aim to improve their functionality,
bioavailability and stability in food, cosmetic and pharmaceutical products.
PB  - Faculty of Technology, Zvornik
C3  - VII International Congress “Engineering, Environment and Materials in Process Industry“
T1  - Alginate-based encapsulation of polyphenols from Rosa canina L. extract
EP  - 136
SP  - 131
DO  - 10.7251/EEMEN2101131J
ER  - 
@conference{
author = "Jovanović, Aleksandra A. and Balanč, Bojana and Šavikin, Katarina and Živković, Jelena and Đorđević, Verica and Bugarski, Branko",
year = "2021",
abstract = "Rosa canina L. (Rosaceae) is frequently employed in traditional medicine, due to its diuretic,
anti-inflammatory, anti-allergic, antioxidant and analgesic effects. It is rich in various bioactive
compounds, including polyphenols, carotenoids, ascorbic acid, mineral elements and fatty acids.
Microencapsulation tehnique is a promising tool for improving R. canina polyphenols'
functionality, stability and bioavailability. Еlectrostatic extrusion process was carried out to
obtain calcium-alginate beads with encapsulated R. canina extract. In pure extract, total
polyphenol content was 103.8±1.9 mg GAE/g, whereas the concentration of flavonoids was
64.2±2.40 mg CE/g. Furthermore, polyphenol and flavonoid contents in extract loaded hydrogel
beads were 4.68±0.12 mg GAE/g and 2.93±0.23 mg CE/g, respectively. Thus, determined
encapsulation efficiency was 45.04±1.15%. In ABTS test, antioxidant activity of pure extract and
extract loaded hydrogel beads was 15.30±2.10 and 2.93±0.23 mg Trolox/g, respectively. In
DPPH test, IC50 of pure extract and extract loaded hydrogel beads was 1.07±0.01 and
29.32±2.15 mg/mL, respectively. The size of the produced R. canina extract encapsulated
hydrogel particles was 550.30±34.56 µm. In distilled water as a medium, most of polyphenols
were released relatively rapidly from alginate beads (in the first 20 min), and the maximum
release plateau was reached at 60 min. This study demonstrates the potential of using alginate
for encapsulation of R. canina polyphenols, with the aim to improve their functionality,
bioavailability and stability in food, cosmetic and pharmaceutical products.",
publisher = "Faculty of Technology, Zvornik",
journal = "VII International Congress “Engineering, Environment and Materials in Process Industry“",
title = "Alginate-based encapsulation of polyphenols from Rosa canina L. extract",
pages = "136-131",
doi = "10.7251/EEMEN2101131J"
}
Jovanović, A. A., Balanč, B., Šavikin, K., Živković, J., Đorđević, V.,& Bugarski, B.. (2021). Alginate-based encapsulation of polyphenols from Rosa canina L. extract. in VII International Congress “Engineering, Environment and Materials in Process Industry“
Faculty of Technology, Zvornik., 131-136.
https://doi.org/10.7251/EEMEN2101131J
Jovanović AA, Balanč B, Šavikin K, Živković J, Đorđević V, Bugarski B. Alginate-based encapsulation of polyphenols from Rosa canina L. extract. in VII International Congress “Engineering, Environment and Materials in Process Industry“. 2021;:131-136.
doi:10.7251/EEMEN2101131J .
Jovanović, Aleksandra A., Balanč, Bojana, Šavikin, Katarina, Živković, Jelena, Đorđević, Verica, Bugarski, Branko, "Alginate-based encapsulation of polyphenols from Rosa canina L. extract" in VII International Congress “Engineering, Environment and Materials in Process Industry“ (2021):131-136,
https://doi.org/10.7251/EEMEN2101131J . .

Polyphenolic content and antioxidant activity of Thymus serpyllum extracts depending on extraction conditions

Jovanović, Aleksandra A.; Petrović, Predrag; Zdunić, Gordana; Šavikin, Katarina; Bugarski, Branko

(Serbian society for mitochondrial and free-radical physiology Ministry of Education, 2015)

TY  - CONF
AU  - Jovanović, Aleksandra A.
AU  - Petrović, Predrag
AU  - Zdunić, Gordana
AU  - Šavikin, Katarina
AU  - Bugarski, Branko
PY  - 2015
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/6416
PB  - Serbian society for mitochondrial and free-radical physiology Ministry of Education
PB  - Science and Technological Development University of Belgrade
PB  - Faculty of Biology University of Belgrade
PB  - Institute for biological research “Siniša Stanković” University of Belgrade
PB  - Faculty of Pharmacy University of Belgrade
PB  - Faculty of Medicine
C3  - Third Congress REDOX MEDICINE Reactive Species Signaling, Analytical Methods, Phytopharmacy, Molecular Mechanisms of Disease
T1  - Polyphenolic content and antioxidant activity of Thymus serpyllum extracts depending on extraction conditions
EP  - 26
UR  - https://hdl.handle.net/21.15107/rcub_technorep_6416
ER  - 
@conference{
author = "Jovanović, Aleksandra A. and Petrović, Predrag and Zdunić, Gordana and Šavikin, Katarina and Bugarski, Branko",
year = "2015",
publisher = "Serbian society for mitochondrial and free-radical physiology Ministry of Education, Science and Technological Development University of Belgrade, Faculty of Biology University of Belgrade, Institute for biological research “Siniša Stanković” University of Belgrade, Faculty of Pharmacy University of Belgrade, Faculty of Medicine",
journal = "Third Congress REDOX MEDICINE Reactive Species Signaling, Analytical Methods, Phytopharmacy, Molecular Mechanisms of Disease",
title = "Polyphenolic content and antioxidant activity of Thymus serpyllum extracts depending on extraction conditions",
pages = "26",
url = "https://hdl.handle.net/21.15107/rcub_technorep_6416"
}
Jovanović, A. A., Petrović, P., Zdunić, G., Šavikin, K.,& Bugarski, B.. (2015). Polyphenolic content and antioxidant activity of Thymus serpyllum extracts depending on extraction conditions. in Third Congress REDOX MEDICINE Reactive Species Signaling, Analytical Methods, Phytopharmacy, Molecular Mechanisms of Disease
Serbian society for mitochondrial and free-radical physiology Ministry of Education..
https://hdl.handle.net/21.15107/rcub_technorep_6416
Jovanović AA, Petrović P, Zdunić G, Šavikin K, Bugarski B. Polyphenolic content and antioxidant activity of Thymus serpyllum extracts depending on extraction conditions. in Third Congress REDOX MEDICINE Reactive Species Signaling, Analytical Methods, Phytopharmacy, Molecular Mechanisms of Disease. 2015;:null-26.
https://hdl.handle.net/21.15107/rcub_technorep_6416 .
Jovanović, Aleksandra A., Petrović, Predrag, Zdunić, Gordana, Šavikin, Katarina, Bugarski, Branko, "Polyphenolic content and antioxidant activity of Thymus serpyllum extracts depending on extraction conditions" in Third Congress REDOX MEDICINE Reactive Species Signaling, Analytical Methods, Phytopharmacy, Molecular Mechanisms of Disease (2015),
https://hdl.handle.net/21.15107/rcub_technorep_6416 .