TY  - JOUR
AU  - Radoičić, Marija B.
AU  - Milošević, Milica V.
AU  - Miličević, Dejan S.
AU  - Suljovrujić, Edin H.
AU  - Ćirić-Marjanović, Gordana N.
AU  - Radetić, Maja
AU  - Šaponjić, Zoran
PY  - 2015
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3131
AB  - Polyester fibers gained significant share from all other man-made fibers, but despite numerous advantages a characteristic static electricity generation is still seeking innovative solutions. In order to improve electrical properties of poly(ethyleneterephthalate) (PET) fabric, coating consisting of polyaniline/TiO2 (PANI/TiO2) nanocomposite was deposited on its surface. Coating was synthesized in acidic medium by the chemical oxidative polymerization of aniline with ammonium peroxydisulfate CAPS) in the presence of colloidal TiO2 nanoparticles (d similar to 4.5 nm) and PET fabric. The morphology, molecular structure and dielectric properties of PANI/TiO2 nanocomposites were studied by scanning electron microscopy (SEM), Raman and dielectric spectroscopies. SEM analysis revealed the formation of non-uniform PANI coating on the reference PET sample. In contrast, uniform PANI/TiO2 coating on the surface of PET fabric was generated when TiO2 nanoparticles were engaged. The existence of conductive emeraldine salt form of PANI and phenazine units was confirmed by Raman spectroscopy. Formation mechanisms of PANI and PANI/TiO2 coatings on PET fabrics were proposed. The presence of TiO2 nanoparticles significantly affected the dielectric properties (permittivity and loss tangent) and AC conductivity of PANI/TiO2 coated PET fabrics. PET fabrics coated by PANI/TiO2 nanocomposite showed up to two orders of magnitude higher conductivity in the measured frequency region compared to PANI coated PET fabric.
PB  - Elsevier Science Sa, Lausanne
T2  - Surface & Coatings Technology
T1  - Influence of TiO2 nanoparticles on formation mechanism of PANI/TiO2 nanocomposite coating on PET fabric and its structural and electrical properties
EP  - 47
SP  - 38
VL  - 278
DO  - 10.1016/j.surfcoat.2015.07.070
ER  - 

@article{
author = "Radoičić, Marija B. and Milošević, Milica V. and Miličević, Dejan S. and Suljovrujić, Edin H. and Ćirić-Marjanović, Gordana N. and Radetić, Maja and Šaponjić, Zoran",
year = "2015",
abstract = "Polyester fibers gained significant share from all other man-made fibers, but despite numerous advantages a characteristic static electricity generation is still seeking innovative solutions. In order to improve electrical properties of poly(ethyleneterephthalate) (PET) fabric, coating consisting of polyaniline/TiO2 (PANI/TiO2) nanocomposite was deposited on its surface. Coating was synthesized in acidic medium by the chemical oxidative polymerization of aniline with ammonium peroxydisulfate CAPS) in the presence of colloidal TiO2 nanoparticles (d similar to 4.5 nm) and PET fabric. The morphology, molecular structure and dielectric properties of PANI/TiO2 nanocomposites were studied by scanning electron microscopy (SEM), Raman and dielectric spectroscopies. SEM analysis revealed the formation of non-uniform PANI coating on the reference PET sample. In contrast, uniform PANI/TiO2 coating on the surface of PET fabric was generated when TiO2 nanoparticles were engaged. The existence of conductive emeraldine salt form of PANI and phenazine units was confirmed by Raman spectroscopy. Formation mechanisms of PANI and PANI/TiO2 coatings on PET fabrics were proposed. The presence of TiO2 nanoparticles significantly affected the dielectric properties (permittivity and loss tangent) and AC conductivity of PANI/TiO2 coated PET fabrics. PET fabrics coated by PANI/TiO2 nanocomposite showed up to two orders of magnitude higher conductivity in the measured frequency region compared to PANI coated PET fabric.",
publisher = "Elsevier Science Sa, Lausanne",
journal = "Surface & Coatings Technology",
title = "Influence of TiO2 nanoparticles on formation mechanism of PANI/TiO2 nanocomposite coating on PET fabric and its structural and electrical properties",
pages = "47-38",
volume = "278",
doi = "10.1016/j.surfcoat.2015.07.070"
}

Radoičić, M. B., Milošević, M. V., Miličević, D. S., Suljovrujić, E. H., Ćirić-Marjanović, G. N., Radetić, M.,& Šaponjić, Z.. (2015). Influence of TiO2 nanoparticles on formation mechanism of PANI/TiO2 nanocomposite coating on PET fabric and its structural and electrical properties. in Surface & Coatings Technology
Elsevier Science Sa, Lausanne., 278, 38-47.
https://doi.org/10.1016/j.surfcoat.2015.07.070

Radoičić MB, Milošević MV, Miličević DS, Suljovrujić EH, Ćirić-Marjanović GN, Radetić M, Šaponjić Z. Influence of TiO2 nanoparticles on formation mechanism of PANI/TiO2 nanocomposite coating on PET fabric and its structural and electrical properties. in Surface & Coatings Technology. 2015;278:38-47.
doi:10.1016/j.surfcoat.2015.07.070 .

Radoičić, Marija B., Milošević, Milica V., Miličević, Dejan S., Suljovrujić, Edin H., Ćirić-Marjanović, Gordana N., Radetić, Maja, Šaponjić, Zoran, "Influence of TiO2 nanoparticles on formation mechanism of PANI/TiO2 nanocomposite coating on PET fabric and its structural and electrical properties" in Surface & Coatings Technology, 278 (2015):38-47,
https://doi.org/10.1016/j.surfcoat.2015.07.070 . .

TY  - JOUR
AU  - Mićić, Maja M.
AU  - Milić-Vukašinović, Tanja
AU  - Mitrić, Miodrag
AU  - Jokić, Bojan M.
AU  - Suljovrujić, Edin H.
PY  - 2013
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/5713
AB  - Silver nanoparticles were fabricated via in situ reduction of silver nitrate embedded in swollen P(HEMA/IA) hydrogel, using gamma radiolysis method. Copolymeric hydrogels based on 2-hydroxyethyl methacrylate (HEMA) and itaconic acid (IA), previously synthesised by gamma radiation for wound dressing application, were used as a carrier and a stabilising agent, while ethyl alcohol was used as a free radical scavenger. The influence of different P(HEMA/IA) hydrogels and silver salt concentrations on the size and distribution of nanoparticles was investigated. The Ag/P(HEMA/IA) nanocomposites were characterised by high resolution scanning electron microscopy, energy dispersive spectroscopy, wide-angle X-ray diffraction, UV-Vis spectroscopy and swelling measurements. Escherichia coli (Gram-negative bacterium), Staphylococcus aureus (Gram-positive bacterium) and Candida albicans (fungus) were used to prove the antimicrobial properties of Ag/P(HEMA/IA) nanocomposites. The inhibition kinetics of bacteria growth was investigated by measuring the colony-forming unit. The antimicrobial effectiveness of the Ag/P(HEMA/IA) hydrogel nanocomposite was demonstrated even at small silver concentrations. P(HEMA/IA) hydrogels containing nanosilver particles was found suitable to be used as wound dressing.
T2  - Polymer Bulletin
T1  - Radiation synthesis, characterisation and antimicrobial application of novel copolymeric silver/poly(2-hydroxyethyl methacrylate/itaconic acid) nanocomposite hydrogels
EP  - 3357
IS  - 12
SP  - 3347
VL  - 70
DO  - 10.1007/s00289-013-1026-9
ER  - 

@article{
author = "Mićić, Maja M. and Milić-Vukašinović, Tanja and Mitrić, Miodrag and Jokić, Bojan M. and Suljovrujić, Edin H.",
year = "2013",
abstract = "Silver nanoparticles were fabricated via in situ reduction of silver nitrate embedded in swollen P(HEMA/IA) hydrogel, using gamma radiolysis method. Copolymeric hydrogels based on 2-hydroxyethyl methacrylate (HEMA) and itaconic acid (IA), previously synthesised by gamma radiation for wound dressing application, were used as a carrier and a stabilising agent, while ethyl alcohol was used as a free radical scavenger. The influence of different P(HEMA/IA) hydrogels and silver salt concentrations on the size and distribution of nanoparticles was investigated. The Ag/P(HEMA/IA) nanocomposites were characterised by high resolution scanning electron microscopy, energy dispersive spectroscopy, wide-angle X-ray diffraction, UV-Vis spectroscopy and swelling measurements. Escherichia coli (Gram-negative bacterium), Staphylococcus aureus (Gram-positive bacterium) and Candida albicans (fungus) were used to prove the antimicrobial properties of Ag/P(HEMA/IA) nanocomposites. The inhibition kinetics of bacteria growth was investigated by measuring the colony-forming unit. The antimicrobial effectiveness of the Ag/P(HEMA/IA) hydrogel nanocomposite was demonstrated even at small silver concentrations. P(HEMA/IA) hydrogels containing nanosilver particles was found suitable to be used as wound dressing.",
journal = "Polymer Bulletin",
title = "Radiation synthesis, characterisation and antimicrobial application of novel copolymeric silver/poly(2-hydroxyethyl methacrylate/itaconic acid) nanocomposite hydrogels",
pages = "3357-3347",
number = "12",
volume = "70",
doi = "10.1007/s00289-013-1026-9"
}

Mićić, M. M., Milić-Vukašinović, T., Mitrić, M., Jokić, B. M.,& Suljovrujić, E. H.. (2013). Radiation synthesis, characterisation and antimicrobial application of novel copolymeric silver/poly(2-hydroxyethyl methacrylate/itaconic acid) nanocomposite hydrogels. in Polymer Bulletin, 70(12), 3347-3357.
https://doi.org/10.1007/s00289-013-1026-9

Mićić MM, Milić-Vukašinović T, Mitrić M, Jokić BM, Suljovrujić EH. Radiation synthesis, characterisation and antimicrobial application of novel copolymeric silver/poly(2-hydroxyethyl methacrylate/itaconic acid) nanocomposite hydrogels. in Polymer Bulletin. 2013;70(12):3347-3357.
doi:10.1007/s00289-013-1026-9 .

Mićić, Maja M., Milić-Vukašinović, Tanja, Mitrić, Miodrag, Jokić, Bojan M., Suljovrujić, Edin H., "Radiation synthesis, characterisation and antimicrobial application of novel copolymeric silver/poly(2-hydroxyethyl methacrylate/itaconic acid) nanocomposite hydrogels" in Polymer Bulletin, 70, no. 12 (2013):3347-3357,
https://doi.org/10.1007/s00289-013-1026-9 . .

TY  - JOUR
AU  - Mićić, Maja M.
AU  - Stamenic, D.
AU  - Suljovrujić, Edin H.
PY  - 2012
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/5735
AB  - Since it is presumed that by incorporation of pH-responsive (IA) and temperature-responsive (OEGA) co-monomers, it is possible to prepare P(HEMA/IA/OEGA) hydrogels with dual (pH and thermo) responsiveness, the main purpose of our study is to investigate the influence of different mole fractions of IA and especially OEGA on the diversity of the swelling properties of the obtained hydrogels. For that reason, a series of terpolymeric hydrogels with different mole ratios of 2-hydroxyethyl methacrylate (HEMA), itaconic acid (IA) and oligo(ethylene glycol) acrylates (OEGA) was synthesised by gamma radiation. The obtained hydrogels were characterised by swelling studies in the wide pH (2.2-9.0) and temperature range (20-70 degrees C), confirming dual (pH and thermo) responsiveness and a large variation in the swelling capability. It was observed that the equilibrium swelling of P(HEMA/IA/OEGA) hydrogels, for a constant amount of IA, increased progressively with an increase in OEGA share. On the other hand, the dissociation of carboxyl groups from IA occurs at pH GT 4; therefore, small mole fractions of IA render good pH sensitivity and a large increase in the swelling capacity of these hydrogels at higher pH values. Additional characterisation of structure and properties was conducted by Fourier transform infrared (FTIR) spectroscopy, scanning electron microscopy (SEM) and mechanical measurements, confirming that the inherent properties of P(HEMA/IA/OEGA) hydrogels can be significantly tuned by variation in their composition. According to all presented, it seems that the obtained hydrogels can be a beneficial synergetic combination for controlled delivery of bioactive molecules such as drugs, peptides, proteins, etc. (C) 2011 Elsevier Ltd. All rights reserved.
T2  - Radiation Physics and Chemistry
T1  - Radiation-induced synthesis and swelling properties of p(2-hydroxyethyl methacrylate/itaconic acid/oligo (ethylene glycol) acrylate) terpolymeric hydrogels
EP  - 1455
IS  - 9
SP  - 1451
VL  - 81
DO  - 10.1016/j.radphyschem.2011.11.024
ER  - 

@article{
author = "Mićić, Maja M. and Stamenic, D. and Suljovrujić, Edin H.",
year = "2012",
abstract = "Since it is presumed that by incorporation of pH-responsive (IA) and temperature-responsive (OEGA) co-monomers, it is possible to prepare P(HEMA/IA/OEGA) hydrogels with dual (pH and thermo) responsiveness, the main purpose of our study is to investigate the influence of different mole fractions of IA and especially OEGA on the diversity of the swelling properties of the obtained hydrogels. For that reason, a series of terpolymeric hydrogels with different mole ratios of 2-hydroxyethyl methacrylate (HEMA), itaconic acid (IA) and oligo(ethylene glycol) acrylates (OEGA) was synthesised by gamma radiation. The obtained hydrogels were characterised by swelling studies in the wide pH (2.2-9.0) and temperature range (20-70 degrees C), confirming dual (pH and thermo) responsiveness and a large variation in the swelling capability. It was observed that the equilibrium swelling of P(HEMA/IA/OEGA) hydrogels, for a constant amount of IA, increased progressively with an increase in OEGA share. On the other hand, the dissociation of carboxyl groups from IA occurs at pH GT 4; therefore, small mole fractions of IA render good pH sensitivity and a large increase in the swelling capacity of these hydrogels at higher pH values. Additional characterisation of structure and properties was conducted by Fourier transform infrared (FTIR) spectroscopy, scanning electron microscopy (SEM) and mechanical measurements, confirming that the inherent properties of P(HEMA/IA/OEGA) hydrogels can be significantly tuned by variation in their composition. According to all presented, it seems that the obtained hydrogels can be a beneficial synergetic combination for controlled delivery of bioactive molecules such as drugs, peptides, proteins, etc. (C) 2011 Elsevier Ltd. All rights reserved.",
journal = "Radiation Physics and Chemistry",
title = "Radiation-induced synthesis and swelling properties of p(2-hydroxyethyl methacrylate/itaconic acid/oligo (ethylene glycol) acrylate) terpolymeric hydrogels",
pages = "1455-1451",
number = "9",
volume = "81",
doi = "10.1016/j.radphyschem.2011.11.024"
}

Mićić, M. M., Stamenic, D.,& Suljovrujić, E. H.. (2012). Radiation-induced synthesis and swelling properties of p(2-hydroxyethyl methacrylate/itaconic acid/oligo (ethylene glycol) acrylate) terpolymeric hydrogels. in Radiation Physics and Chemistry, 81(9), 1451-1455.
https://doi.org/10.1016/j.radphyschem.2011.11.024

Mićić MM, Stamenic D, Suljovrujić EH. Radiation-induced synthesis and swelling properties of p(2-hydroxyethyl methacrylate/itaconic acid/oligo (ethylene glycol) acrylate) terpolymeric hydrogels. in Radiation Physics and Chemistry. 2012;81(9):1451-1455.
doi:10.1016/j.radphyschem.2011.11.024 .

Mićić, Maja M., Stamenic, D., Suljovrujić, Edin H., "Radiation-induced synthesis and swelling properties of p(2-hydroxyethyl methacrylate/itaconic acid/oligo (ethylene glycol) acrylate) terpolymeric hydrogels" in Radiation Physics and Chemistry, 81, no. 9 (2012):1451-1455,
https://doi.org/10.1016/j.radphyschem.2011.11.024 . .

TY  - JOUR
AU  - Jovašević, Jovana S.
AU  - Dimitrijević, Suzana
AU  - Filipović, Jovanka M.
AU  - Tomić, Simonida
AU  - Mićić, Maja M.
AU  - Suljovrujić, Edin H.
PY  - 2011
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/1947
AB  - A simple and fast approach to the design and production of new hybrid polymeric biomaterials with silver particles is presented in this work. Silver/semi-interpenetrating network hybrid hydrogels (Ag/semi-IPNHHs) were prepared through an optimized solution crosslinking copolymerization of 2-hydroxyethyl methacrylate (HEMA) and itaconic acid (IA), in the presence of PVP, a silver salt and a reducing "green" agent (Ag/P(HEMA/IA)/PVP). PVP was chosen due to its protective, reduction, and nucleation properties in the production of metal particles. The structure of the Ag/semi-IPNHH was characterized by Fourier transform infrared spectroscopy (FTIR). The presence of silver and PVP in the network was confirmed by FTIR spectra. The results obtained by dynamic mechanical analysis (DMA) showed good mechanical properties for all samples. The swelling studies of Ag/P(HEMA/IA)/PVP were conducted in the temperature range of 25-55 degrees C, in the buffer of pH 7.40. The Ag/semi-IPNHH showed temperature-sensitive swelling properties, with the lower critical solution temperature (LCST) values in the physiologically interesting interval. The antimicrobial activity of the samples was tested using E. coli, S. aureus and C. albicans pathogens. It was concluded that the antimicrobial potential depends on the hydrogel's composition and the type of microbes
PB  - Polish Acad Sciences Inst Physics, Warsaw
T2  - Acta Physica Polonica A
T1  - Swelling, Mechanical and Antimicrobial Studies of Ag/P(HEMA/IA)/PVP Semi-IPN Hybrid Hydrogels
EP  - 283
IS  - 2
SP  - 279
VL  - 120
DO  - 10.12693/APhysPolA.120.279
ER  - 

@article{
author = "Jovašević, Jovana S. and Dimitrijević, Suzana and Filipović, Jovanka M. and Tomić, Simonida and Mićić, Maja M. and Suljovrujić, Edin H.",
year = "2011",
abstract = "A simple and fast approach to the design and production of new hybrid polymeric biomaterials with silver particles is presented in this work. Silver/semi-interpenetrating network hybrid hydrogels (Ag/semi-IPNHHs) were prepared through an optimized solution crosslinking copolymerization of 2-hydroxyethyl methacrylate (HEMA) and itaconic acid (IA), in the presence of PVP, a silver salt and a reducing "green" agent (Ag/P(HEMA/IA)/PVP). PVP was chosen due to its protective, reduction, and nucleation properties in the production of metal particles. The structure of the Ag/semi-IPNHH was characterized by Fourier transform infrared spectroscopy (FTIR). The presence of silver and PVP in the network was confirmed by FTIR spectra. The results obtained by dynamic mechanical analysis (DMA) showed good mechanical properties for all samples. The swelling studies of Ag/P(HEMA/IA)/PVP were conducted in the temperature range of 25-55 degrees C, in the buffer of pH 7.40. The Ag/semi-IPNHH showed temperature-sensitive swelling properties, with the lower critical solution temperature (LCST) values in the physiologically interesting interval. The antimicrobial activity of the samples was tested using E. coli, S. aureus and C. albicans pathogens. It was concluded that the antimicrobial potential depends on the hydrogel's composition and the type of microbes",
publisher = "Polish Acad Sciences Inst Physics, Warsaw",
journal = "Acta Physica Polonica A",
title = "Swelling, Mechanical and Antimicrobial Studies of Ag/P(HEMA/IA)/PVP Semi-IPN Hybrid Hydrogels",
pages = "283-279",
number = "2",
volume = "120",
doi = "10.12693/APhysPolA.120.279"
}

Jovašević, J. S., Dimitrijević, S., Filipović, J. M., Tomić, S., Mićić, M. M.,& Suljovrujić, E. H.. (2011). Swelling, Mechanical and Antimicrobial Studies of Ag/P(HEMA/IA)/PVP Semi-IPN Hybrid Hydrogels. in Acta Physica Polonica A
Polish Acad Sciences Inst Physics, Warsaw., 120(2), 279-283.
https://doi.org/10.12693/APhysPolA.120.279

Jovašević JS, Dimitrijević S, Filipović JM, Tomić S, Mićić MM, Suljovrujić EH. Swelling, Mechanical and Antimicrobial Studies of Ag/P(HEMA/IA)/PVP Semi-IPN Hybrid Hydrogels. in Acta Physica Polonica A. 2011;120(2):279-283.
doi:10.12693/APhysPolA.120.279 .

Jovašević, Jovana S., Dimitrijević, Suzana, Filipović, Jovanka M., Tomić, Simonida, Mićić, Maja M., Suljovrujić, Edin H., "Swelling, Mechanical and Antimicrobial Studies of Ag/P(HEMA/IA)/PVP Semi-IPN Hybrid Hydrogels" in Acta Physica Polonica A, 120, no. 2 (2011):279-283,
https://doi.org/10.12693/APhysPolA.120.279 . .

TY  - JOUR
AU  - Jovašević, Jovana S.
AU  - Mićić, Maja M.
AU  - Suljovrujić, Edin H.
AU  - Filipović, Jovanka M.
AU  - Dimitrijević, Suzana
AU  - Tomić, Simonida
PY  - 2010
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/1624
AB  - New hybrid hydrogels were prepared by radical copolymerization of 2-hydroxyethyl methacrylate, itaconic acid, poly(vinylpyrrolidone) and silver salt. FTIR spectroscopy has confirmed binding of silver particles in hydrogels. Swelling studies performed in in vitro conditions showed dependence on PVP content and temperature. It can be seen that the antimicrobial activity of the Ag/P(HEMA/IA)PVP hybrid hydrogels depends on the PVP moiety and with the increase of PVP content the microbial contamination is more efficiently reduced. The best sensitivity was obtained for the polymers tested for antimicrobial activity against the yeast C. albicans, one of the most commonly encountered human pathogens, causing a wide variety of infections ranging from mucosal infections in generally healthy persons to life-threatening systemic infections in individuals with impaired immunity. A slightly less susceptible to antimicrobial effect of hydrogels was obtained for the Gram-positive bacteria S. aureus, where the reduction of cells was about 70% after two hours of exposure, for the sample with the highest PVP content. The least susceptible to the antimicrobial activity of hydrogels examined was the Gram-negative bacteria E. coli, where the percent of cell reduction was below 20%. Bearing in mind the influence of the time of exposure of microbes to the Ag/ /P(HEMA/IA)/PVP hybrid hydrogels, it was observed that the reduction of the number of cells depends on time, microbial culture and type of hybrid hydrogel sample. Due to their swelling and antimicrobial properties, silver/poly(2-hydroxyethyl methacrylate/itaconic acid)/poly(vinylpyrrolidone) hybrid hydrogles show potential to use in the field of biomedicine, especially for treatment of skin and burns in dermocosmetics.
AB  - U radu je prikazana sinteza niza hibridnih hidrogelova na bazi 2-hidroksietil metakrilata, itakonske kiseline i poli(vinilpirolidona) u koje su ugrađene čestice srebra, s ciljem primene ovih sistema u biomedicinske svrhe. Određene su strukturne karakteristike hidrogelova. Bubrenja gelova je izvedeno u in vitro uslovima i pokazana je zavisnost stepena bubrenja od temperature i udela PVP. Ispitivanje antimikrobne aktivnosti hidrogelova je izvedeno korišćenjem mikrobnih kultura E. coli, S. aureus i C. albicans. Najveću osetljivost nakon izlaganja uzorcima pokazuje patogeni kvasac C. albicans, a najmanju bakterija E. coli. Može se izvesti zaključak da su svi sintetisani hibridni hidrogelovi pokazali povoljna difuziona svojstva u in vitro uslovima, kao i da antimikrobna aktivnost zavisi od vrste hidrogela i soja mikroba, i vremena izlaganja hidrogelova testiranim mikrobima.
PB  - Association of Chemical Engineers of Serbia
T2  - Hemijska industrija
T1  - Antimicrobial activity of hybrid hydrogels based on poly(vinylpyrrolidone) containing silver
T1  - Antimikrobna aktivnost hibridnih hidrogelova na bazi poli(vinilpirolidona) koji sadrže srebro
EP  - 214
IS  - 3
SP  - 209
VL  - 64
DO  - 10.2298/HEMIND091221030J
ER  - 

@article{
author = "Jovašević, Jovana S. and Mićić, Maja M. and Suljovrujić, Edin H. and Filipović, Jovanka M. and Dimitrijević, Suzana and Tomić, Simonida",
year = "2010",
abstract = "New hybrid hydrogels were prepared by radical copolymerization of 2-hydroxyethyl methacrylate, itaconic acid, poly(vinylpyrrolidone) and silver salt. FTIR spectroscopy has confirmed binding of silver particles in hydrogels. Swelling studies performed in in vitro conditions showed dependence on PVP content and temperature. It can be seen that the antimicrobial activity of the Ag/P(HEMA/IA)PVP hybrid hydrogels depends on the PVP moiety and with the increase of PVP content the microbial contamination is more efficiently reduced. The best sensitivity was obtained for the polymers tested for antimicrobial activity against the yeast C. albicans, one of the most commonly encountered human pathogens, causing a wide variety of infections ranging from mucosal infections in generally healthy persons to life-threatening systemic infections in individuals with impaired immunity. A slightly less susceptible to antimicrobial effect of hydrogels was obtained for the Gram-positive bacteria S. aureus, where the reduction of cells was about 70% after two hours of exposure, for the sample with the highest PVP content. The least susceptible to the antimicrobial activity of hydrogels examined was the Gram-negative bacteria E. coli, where the percent of cell reduction was below 20%. Bearing in mind the influence of the time of exposure of microbes to the Ag/ /P(HEMA/IA)/PVP hybrid hydrogels, it was observed that the reduction of the number of cells depends on time, microbial culture and type of hybrid hydrogel sample. Due to their swelling and antimicrobial properties, silver/poly(2-hydroxyethyl methacrylate/itaconic acid)/poly(vinylpyrrolidone) hybrid hydrogles show potential to use in the field of biomedicine, especially for treatment of skin and burns in dermocosmetics., U radu je prikazana sinteza niza hibridnih hidrogelova na bazi 2-hidroksietil metakrilata, itakonske kiseline i poli(vinilpirolidona) u koje su ugrađene čestice srebra, s ciljem primene ovih sistema u biomedicinske svrhe. Određene su strukturne karakteristike hidrogelova. Bubrenja gelova je izvedeno u in vitro uslovima i pokazana je zavisnost stepena bubrenja od temperature i udela PVP. Ispitivanje antimikrobne aktivnosti hidrogelova je izvedeno korišćenjem mikrobnih kultura E. coli, S. aureus i C. albicans. Najveću osetljivost nakon izlaganja uzorcima pokazuje patogeni kvasac C. albicans, a najmanju bakterija E. coli. Može se izvesti zaključak da su svi sintetisani hibridni hidrogelovi pokazali povoljna difuziona svojstva u in vitro uslovima, kao i da antimikrobna aktivnost zavisi od vrste hidrogela i soja mikroba, i vremena izlaganja hidrogelova testiranim mikrobima.",
publisher = "Association of Chemical Engineers of Serbia",
journal = "Hemijska industrija",
title = "Antimicrobial activity of hybrid hydrogels based on poly(vinylpyrrolidone) containing silver, Antimikrobna aktivnost hibridnih hidrogelova na bazi poli(vinilpirolidona) koji sadrže srebro",
pages = "214-209",
number = "3",
volume = "64",
doi = "10.2298/HEMIND091221030J"
}

Jovašević, J. S., Mićić, M. M., Suljovrujić, E. H., Filipović, J. M., Dimitrijević, S.,& Tomić, S.. (2010). Antimicrobial activity of hybrid hydrogels based on poly(vinylpyrrolidone) containing silver. in Hemijska industrija
Association of Chemical Engineers of Serbia., 64(3), 209-214.
https://doi.org/10.2298/HEMIND091221030J

Jovašević JS, Mićić MM, Suljovrujić EH, Filipović JM, Dimitrijević S, Tomić S. Antimicrobial activity of hybrid hydrogels based on poly(vinylpyrrolidone) containing silver. in Hemijska industrija. 2010;64(3):209-214.
doi:10.2298/HEMIND091221030J .

Jovašević, Jovana S., Mićić, Maja M., Suljovrujić, Edin H., Filipović, Jovanka M., Dimitrijević, Suzana, Tomić, Simonida, "Antimicrobial activity of hybrid hydrogels based on poly(vinylpyrrolidone) containing silver" in Hemijska industrija, 64, no. 3 (2010):209-214,
https://doi.org/10.2298/HEMIND091221030J . .

TY  - JOUR
AU  - Tomić, Simonida
AU  - Mićić, Maja M.
AU  - Dobić, Sava N.
AU  - Filipović, Jovanka M.
AU  - Suljovrujić, Edin H.
PY  - 2010
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/1707
AB  - pH- and temperature-sensitive hydrogels, based on 2-hydroxyethyl methacrylate (HEMA) and itaconic acid (IA) copolymers, were prepared by gamma-irradiation and characterized in order to examine their potential use in biomedical applications. The influence of comonomer ratio in these smart copolymers on their morphology, mechanical and thermal properties, biocompatibility and microbe penetration capability was investigated. The mechanical properties of copolymers were investigated using the dynamic mechanical analysis (DMA), while their thermal properties and morphology were examined by thermogravimetric analysis (TGA) and scanning electron microscopy (SEM). The morphology, mechanical and thermal properties of these hydrogels were found to be suitable for most requirements of biomedical applications. The in vitro study of P(HEMA/IA) biocompatibility showed no evidence of cell toxicity nor any considerable hemolytic activity. Furthermore, the microbe penetration test showed that neither Staphylococcus aureus nor Escherichia coli passed through the hydogel dressing; thus the P(HEMA/IA) dressing could be considered a good barrier against microbes. All results indicate that stimuli-responsive P(HEMA/IA) hydrogels have great potential for biomedical applications, especially for skin treatment and wound dressings.
PB  - Pergamon-Elsevier Science Ltd, Oxford
T2  - Radiation Physics and Chemistry
T1  - Smart poly(2-hydroxyethyl methacrylate/itaconic acid) hydrogels for biomedical application
EP  - 649
IS  - 5
SP  - 643
VL  - 79
DO  - 10.1016/j.radphyschem.2009.11.015
ER  - 

@article{
author = "Tomić, Simonida and Mićić, Maja M. and Dobić, Sava N. and Filipović, Jovanka M. and Suljovrujić, Edin H.",
year = "2010",
abstract = "pH- and temperature-sensitive hydrogels, based on 2-hydroxyethyl methacrylate (HEMA) and itaconic acid (IA) copolymers, were prepared by gamma-irradiation and characterized in order to examine their potential use in biomedical applications. The influence of comonomer ratio in these smart copolymers on their morphology, mechanical and thermal properties, biocompatibility and microbe penetration capability was investigated. The mechanical properties of copolymers were investigated using the dynamic mechanical analysis (DMA), while their thermal properties and morphology were examined by thermogravimetric analysis (TGA) and scanning electron microscopy (SEM). The morphology, mechanical and thermal properties of these hydrogels were found to be suitable for most requirements of biomedical applications. The in vitro study of P(HEMA/IA) biocompatibility showed no evidence of cell toxicity nor any considerable hemolytic activity. Furthermore, the microbe penetration test showed that neither Staphylococcus aureus nor Escherichia coli passed through the hydogel dressing; thus the P(HEMA/IA) dressing could be considered a good barrier against microbes. All results indicate that stimuli-responsive P(HEMA/IA) hydrogels have great potential for biomedical applications, especially for skin treatment and wound dressings.",
publisher = "Pergamon-Elsevier Science Ltd, Oxford",
journal = "Radiation Physics and Chemistry",
title = "Smart poly(2-hydroxyethyl methacrylate/itaconic acid) hydrogels for biomedical application",
pages = "649-643",
number = "5",
volume = "79",
doi = "10.1016/j.radphyschem.2009.11.015"
}

Tomić, S., Mićić, M. M., Dobić, S. N., Filipović, J. M.,& Suljovrujić, E. H.. (2010). Smart poly(2-hydroxyethyl methacrylate/itaconic acid) hydrogels for biomedical application. in Radiation Physics and Chemistry
Pergamon-Elsevier Science Ltd, Oxford., 79(5), 643-649.
https://doi.org/10.1016/j.radphyschem.2009.11.015

Tomić S, Mićić MM, Dobić SN, Filipović JM, Suljovrujić EH. Smart poly(2-hydroxyethyl methacrylate/itaconic acid) hydrogels for biomedical application. in Radiation Physics and Chemistry. 2010;79(5):643-649.
doi:10.1016/j.radphyschem.2009.11.015 .

Tomić, Simonida, Mićić, Maja M., Dobić, Sava N., Filipović, Jovanka M., Suljovrujić, Edin H., "Smart poly(2-hydroxyethyl methacrylate/itaconic acid) hydrogels for biomedical application" in Radiation Physics and Chemistry, 79, no. 5 (2010):643-649,
https://doi.org/10.1016/j.radphyschem.2009.11.015 . .

TY  - JOUR
AU  - Tomić, Simonida
AU  - Mićić, Maja M.
AU  - Filipović, Jovanka M.
AU  - Suljovrujić, Edin H.
PY  - 2010
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/1620
AB  - In this work, novel hydrogels based on 2-hydroxyethyl methacrylate (HEMA) and different poly(alkylene glycol)(meth)acrylates (BIS) were prepared by radiation-induced copolymerization. The influence of different BIS types with variation in chain length, based on ethylene glycol (EG) and/or propylene glycol (PG) pendant units, on the nature and inherent properties of P(HEMA/BIS) copolymeric hydrogels was the main idea of this paper. Swelling studies were conducted for all types of P(HEMA/BIS) copolymeric hydrogels in a wide pH and temperature range. Additional characterization of structure, morphology and thermal behaviour of the obtained hydrogels was conducted by Fourier transform infrared (FTIR) spectroscopy, scanning electron microscopy (SEM), and thermogravimetric (TG) analysis. The modelling of drug release and diffusion characteristics was tested using cephalexin (CEX). The results indicate that P(HEMA/BIS) hydrogels' properties are significantly dependent on the type of BIS. The hydrogels with ethylene glycol (EG) pendant chains show a noticeable pH and/or temperature sensitivity and can be considered smart hydrogels. The introduction of propylene glycol (PG) units, pure and mixed with ethylene glycol (EG) pendant chains, can additionally tune the characteristics of such gels. Furthermore, drug release studies indicate that these types of P(HEMA/BIS) copolymeric hydrogels are suitable candidates for controlled drug release systems.
PB  - Elsevier Science Sa, Lausanne
T2  - Chemical Engineering Journal
T1  - Synthesis, characterization and controlled release of cephalexin drug from smart poly(2-hydroxyethyl methacrylate/poly(alkylene glycol)(meth)acrylates hydrogels
EP  - 809
IS  - 2
SP  - 801
VL  - 160
DO  - 10.1016/j.cej.2010.03.089
ER  - 

@article{
author = "Tomić, Simonida and Mićić, Maja M. and Filipović, Jovanka M. and Suljovrujić, Edin H.",
year = "2010",
abstract = "In this work, novel hydrogels based on 2-hydroxyethyl methacrylate (HEMA) and different poly(alkylene glycol)(meth)acrylates (BIS) were prepared by radiation-induced copolymerization. The influence of different BIS types with variation in chain length, based on ethylene glycol (EG) and/or propylene glycol (PG) pendant units, on the nature and inherent properties of P(HEMA/BIS) copolymeric hydrogels was the main idea of this paper. Swelling studies were conducted for all types of P(HEMA/BIS) copolymeric hydrogels in a wide pH and temperature range. Additional characterization of structure, morphology and thermal behaviour of the obtained hydrogels was conducted by Fourier transform infrared (FTIR) spectroscopy, scanning electron microscopy (SEM), and thermogravimetric (TG) analysis. The modelling of drug release and diffusion characteristics was tested using cephalexin (CEX). The results indicate that P(HEMA/BIS) hydrogels' properties are significantly dependent on the type of BIS. The hydrogels with ethylene glycol (EG) pendant chains show a noticeable pH and/or temperature sensitivity and can be considered smart hydrogels. The introduction of propylene glycol (PG) units, pure and mixed with ethylene glycol (EG) pendant chains, can additionally tune the characteristics of such gels. Furthermore, drug release studies indicate that these types of P(HEMA/BIS) copolymeric hydrogels are suitable candidates for controlled drug release systems.",
publisher = "Elsevier Science Sa, Lausanne",
journal = "Chemical Engineering Journal",
title = "Synthesis, characterization and controlled release of cephalexin drug from smart poly(2-hydroxyethyl methacrylate/poly(alkylene glycol)(meth)acrylates hydrogels",
pages = "809-801",
number = "2",
volume = "160",
doi = "10.1016/j.cej.2010.03.089"
}

Tomić, S., Mićić, M. M., Filipović, J. M.,& Suljovrujić, E. H.. (2010). Synthesis, characterization and controlled release of cephalexin drug from smart poly(2-hydroxyethyl methacrylate/poly(alkylene glycol)(meth)acrylates hydrogels. in Chemical Engineering Journal
Elsevier Science Sa, Lausanne., 160(2), 801-809.
https://doi.org/10.1016/j.cej.2010.03.089

Tomić S, Mićić MM, Filipović JM, Suljovrujić EH. Synthesis, characterization and controlled release of cephalexin drug from smart poly(2-hydroxyethyl methacrylate/poly(alkylene glycol)(meth)acrylates hydrogels. in Chemical Engineering Journal. 2010;160(2):801-809.
doi:10.1016/j.cej.2010.03.089 .

Tomić, Simonida, Mićić, Maja M., Filipović, Jovanka M., Suljovrujić, Edin H., "Synthesis, characterization and controlled release of cephalexin drug from smart poly(2-hydroxyethyl methacrylate/poly(alkylene glycol)(meth)acrylates hydrogels" in Chemical Engineering Journal, 160, no. 2 (2010):801-809,
https://doi.org/10.1016/j.cej.2010.03.089 . .

TY  - JOUR
AU  - Tomić, Simonida
AU  - Mićić, Maja M.
AU  - Krezović, Bojana D.
AU  - Dobić, Sava N.
AU  - Suljovrujić, Edin H.
AU  - Filipović, Jovanka M.
PY  - 2009
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/1400
AB  - pH and temperature sensitive hydrogels, based on 2-hydroxyethyl methacrylate (HEMA) and itaconic acid (IA) copolymers, were prepared by gamma irradiation and characterized in order to examine their potential use in biomedical applications. The influence of comonomer ratio in these smart copolymers on their morphology, mechanical properties, biocompatibility and microbe penetration capability was investigated. The mechanical properties of copolymers were investigated using the dynamic mechanical analysis (DMA), while their morphology was examined by scanning electron microscopy (SEM). The morphology and mechanical properties of these hydrogels were found to be suitable for most requirements of biomedical applications. The in vitro study of P(HEMA/IA) biocompatibility showed no evidence of cell toxicity nor any considerable hemolytic activity. Furthermore, the microbe penetration test showed that neither Staphylococcus aureus nor Escherichia coli passed through the hydogel dressing; thus the P(HEMA/IA) dressing could be considered a good barrier against microbes. All results indicate that stimuli-responsive P(HEMA/IA) hydrogels have great potential for biomedical applications, especially for skin treatment and wound dressings.
AB  - pH i temperaturno osetljivi hidrogelovi na bazi kopolimera 2-hidroksietilmetakrilata (HEMA) i itakonske kiseline (IK) sintetisani su upotrebom gama zračenja i karakterisani s ciljem ispitivanja njihove potencijalne primene kao biomaterijala. Ispitivan je uticaj odnosa komonomera u ovim inteligentnim polimernim biomaterijalima na morfologiju, mehanička svojstva, biokompatibilnost i penetraciju mikroba. Mehanička svojstva kopolimera su ispitivana dinamičko-mehaničkom analizom (DMA), dok je morfologija karakterisana skenirajućom elektronskom mikroskopijom (SEM). Pokazalo se da su morfologija i mehanička svojstva ovih hidrogelova odgovarajući za većinu biomedicinskih primena. In vitro analizom biokompatibilnosti P(HEMA/IK) hidrogelova potvrđeno je da nisu toksični za ćelije niti izazivaju značajnu hemolitičku aktivnost. Takođe, test mikrobne penetracije pokazao je da ni Staphylococcus aureus ni Escherichia coli ne prolaze kroz hidrogelne obloge; stoga se P(HEMA/IK) obloge mogu smatrati dobrom barijerom protiv mikroba, a radi održavanja sterilnosti okolne sredine. Svi rezultati pokazuju da P(HEMA/IK) hidrogelovi imaju veliku mogućnost primene u biomedicini, posebno kod tretmana kože i kao obloge za opekotine.
PB  - Association of Chemical Engineers of Serbia
T2  - Hemijska industrija
T1  - Smart hydrogels based on itaconic acid for biomedical application
T1  - Inteligentni hidrogelovi na bazi itakonske kiseline za biomedicinsku primenu
EP  - 610
IS  - 6
SP  - 603
VL  - 63
DO  - 10.2298/HEMIND0906603T
ER  - 

@article{
author = "Tomić, Simonida and Mićić, Maja M. and Krezović, Bojana D. and Dobić, Sava N. and Suljovrujić, Edin H. and Filipović, Jovanka M.",
year = "2009",
abstract = "pH and temperature sensitive hydrogels, based on 2-hydroxyethyl methacrylate (HEMA) and itaconic acid (IA) copolymers, were prepared by gamma irradiation and characterized in order to examine their potential use in biomedical applications. The influence of comonomer ratio in these smart copolymers on their morphology, mechanical properties, biocompatibility and microbe penetration capability was investigated. The mechanical properties of copolymers were investigated using the dynamic mechanical analysis (DMA), while their morphology was examined by scanning electron microscopy (SEM). The morphology and mechanical properties of these hydrogels were found to be suitable for most requirements of biomedical applications. The in vitro study of P(HEMA/IA) biocompatibility showed no evidence of cell toxicity nor any considerable hemolytic activity. Furthermore, the microbe penetration test showed that neither Staphylococcus aureus nor Escherichia coli passed through the hydogel dressing; thus the P(HEMA/IA) dressing could be considered a good barrier against microbes. All results indicate that stimuli-responsive P(HEMA/IA) hydrogels have great potential for biomedical applications, especially for skin treatment and wound dressings., pH i temperaturno osetljivi hidrogelovi na bazi kopolimera 2-hidroksietilmetakrilata (HEMA) i itakonske kiseline (IK) sintetisani su upotrebom gama zračenja i karakterisani s ciljem ispitivanja njihove potencijalne primene kao biomaterijala. Ispitivan je uticaj odnosa komonomera u ovim inteligentnim polimernim biomaterijalima na morfologiju, mehanička svojstva, biokompatibilnost i penetraciju mikroba. Mehanička svojstva kopolimera su ispitivana dinamičko-mehaničkom analizom (DMA), dok je morfologija karakterisana skenirajućom elektronskom mikroskopijom (SEM). Pokazalo se da su morfologija i mehanička svojstva ovih hidrogelova odgovarajući za većinu biomedicinskih primena. In vitro analizom biokompatibilnosti P(HEMA/IK) hidrogelova potvrđeno je da nisu toksični za ćelije niti izazivaju značajnu hemolitičku aktivnost. Takođe, test mikrobne penetracije pokazao je da ni Staphylococcus aureus ni Escherichia coli ne prolaze kroz hidrogelne obloge; stoga se P(HEMA/IK) obloge mogu smatrati dobrom barijerom protiv mikroba, a radi održavanja sterilnosti okolne sredine. Svi rezultati pokazuju da P(HEMA/IK) hidrogelovi imaju veliku mogućnost primene u biomedicini, posebno kod tretmana kože i kao obloge za opekotine.",
publisher = "Association of Chemical Engineers of Serbia",
journal = "Hemijska industrija",
title = "Smart hydrogels based on itaconic acid for biomedical application, Inteligentni hidrogelovi na bazi itakonske kiseline za biomedicinsku primenu",
pages = "610-603",
number = "6",
volume = "63",
doi = "10.2298/HEMIND0906603T"
}

Tomić, S., Mićić, M. M., Krezović, B. D., Dobić, S. N., Suljovrujić, E. H.,& Filipović, J. M.. (2009). Smart hydrogels based on itaconic acid for biomedical application. in Hemijska industrija
Association of Chemical Engineers of Serbia., 63(6), 603-610.
https://doi.org/10.2298/HEMIND0906603T

Tomić S, Mićić MM, Krezović BD, Dobić SN, Suljovrujić EH, Filipović JM. Smart hydrogels based on itaconic acid for biomedical application. in Hemijska industrija. 2009;63(6):603-610.
doi:10.2298/HEMIND0906603T .

Tomić, Simonida, Mićić, Maja M., Krezović, Bojana D., Dobić, Sava N., Suljovrujić, Edin H., Filipović, Jovanka M., "Smart hydrogels based on itaconic acid for biomedical application" in Hemijska industrija, 63, no. 6 (2009):603-610,
https://doi.org/10.2298/HEMIND0906603T . .

TY  - JOUR
AU  - Mićić, Maja M.
AU  - Tomić, Simonida
AU  - Filipović, Jovanka M.
AU  - Suljovrujić, Edin H.
PY  - 2009
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/1407
AB  - Silver(I) itaconic acid-based hydrogel complexes were synthesized and characterized in order to examine the potential use of these systems; FTIR, AFM, in vitro fluid-uptake, metal sorption and antibacterial activity assay measurements were used for the characterization. Metal (silver(I)) ion uptaken by IA-based hydrogels was determined by inductively coupled plasma mass spectrometry. The coordination sites for metal ions were identified and the stability in in vitro condition was determined. Incorporation of silver(I) ions into hydrogels and the influence of these ions on the diffusion properties of hydrogels were analyzed and discussed, too; it was found that the itaconic acid moiety in hydrogels is the determining factor which influences metal ion binding and therefore fluid uptake inside the polymeric network. Furthermore, silver(I) itaconic acid-based hydrogel showed a satisfactory antibacterial activity. The most advanced feature of these materials is that the silver ions embedded throughout the networks leaches out via controlled manner with time in aqueous media. Therefore, the ions escape from the swollen networks with time and interact with the bacteria. Because of a good dispersion of silver ions in Ag(I)-P(HEMA/2IA) hydrogel complex, we have evaluated the antibacterial activity for this sample. As expected, the number of colonies grown surrounding the Ag(I)-P(HEMA/2IA) hydrogel complex was found to be almost nil, whereas the pure P(HEMA/2IA) hydrogel did not show any effect on Escherichia coli. Therefore, we conclude that the Ag(I)-P(HEMA/IA) hydrogel complexes are excellent antibacterial materials. Due to these facts, the silver ion IA-based hydrogel complexes reported here might be used as smart materials in the range of biomedical applications, including drug-delivery devices, biosensors, wound healing dressings, tissue reconstruction and organ repair.
AB  - Sintetisani su kompleksi srebra(I) sa kopolimernim hidrogelovima 2-hidroksietil metakrilata (HEMA) i itakonske kiseline (IK) (Ag(I)-P(HEMA/IK)) u cilju ispitivanja primene ovih sistema kao biomaterijala. Uzorci su karakterisani sledećim metodama: FTIR, AFM, analiza bubrenja u in vitro uslovima, apsorpcija metala i analiza antibakterijske aktivnosti. Apsorpcija srebra(I) u hidrogelove na bazi IK je određena metodom indukovano spregnutne plazma-masene spektrometrije (ICP-MS). Analiziran je uticaj ugrađenih jona Ag na difuziona svojstva komplesiranih hidrogelova. Udeo IK u hidrogelu je preovlađujući faktor koji utiče na vezivanje Ag jona, pa otuda i na apsorpciju fluida u polimernoj mreži. Testovi antibakterijske aktivnosti su pokazali zadovoljavajuća antibakterijska svojstva biomaterijala u odnosu na soj bakterija Escherichia coli.
PB  - Association of Chemical Engineers of Serbia
T2  - Hemijska industrija
T1  - Silver(I)-complexes with an itaconic acid-based hydrogel
T1  - Kompleksi srebra I kopolimernih hidrogelova na bazi itakonske kiseline
EP  - 142
IS  - 3
SP  - 137
VL  - 63
DO  - 10.2298/HEMIND0903137M
ER  - 

@article{
author = "Mićić, Maja M. and Tomić, Simonida and Filipović, Jovanka M. and Suljovrujić, Edin H.",
year = "2009",
abstract = "Silver(I) itaconic acid-based hydrogel complexes were synthesized and characterized in order to examine the potential use of these systems; FTIR, AFM, in vitro fluid-uptake, metal sorption and antibacterial activity assay measurements were used for the characterization. Metal (silver(I)) ion uptaken by IA-based hydrogels was determined by inductively coupled plasma mass spectrometry. The coordination sites for metal ions were identified and the stability in in vitro condition was determined. Incorporation of silver(I) ions into hydrogels and the influence of these ions on the diffusion properties of hydrogels were analyzed and discussed, too; it was found that the itaconic acid moiety in hydrogels is the determining factor which influences metal ion binding and therefore fluid uptake inside the polymeric network. Furthermore, silver(I) itaconic acid-based hydrogel showed a satisfactory antibacterial activity. The most advanced feature of these materials is that the silver ions embedded throughout the networks leaches out via controlled manner with time in aqueous media. Therefore, the ions escape from the swollen networks with time and interact with the bacteria. Because of a good dispersion of silver ions in Ag(I)-P(HEMA/2IA) hydrogel complex, we have evaluated the antibacterial activity for this sample. As expected, the number of colonies grown surrounding the Ag(I)-P(HEMA/2IA) hydrogel complex was found to be almost nil, whereas the pure P(HEMA/2IA) hydrogel did not show any effect on Escherichia coli. Therefore, we conclude that the Ag(I)-P(HEMA/IA) hydrogel complexes are excellent antibacterial materials. Due to these facts, the silver ion IA-based hydrogel complexes reported here might be used as smart materials in the range of biomedical applications, including drug-delivery devices, biosensors, wound healing dressings, tissue reconstruction and organ repair., Sintetisani su kompleksi srebra(I) sa kopolimernim hidrogelovima 2-hidroksietil metakrilata (HEMA) i itakonske kiseline (IK) (Ag(I)-P(HEMA/IK)) u cilju ispitivanja primene ovih sistema kao biomaterijala. Uzorci su karakterisani sledećim metodama: FTIR, AFM, analiza bubrenja u in vitro uslovima, apsorpcija metala i analiza antibakterijske aktivnosti. Apsorpcija srebra(I) u hidrogelove na bazi IK je određena metodom indukovano spregnutne plazma-masene spektrometrije (ICP-MS). Analiziran je uticaj ugrađenih jona Ag na difuziona svojstva komplesiranih hidrogelova. Udeo IK u hidrogelu je preovlađujući faktor koji utiče na vezivanje Ag jona, pa otuda i na apsorpciju fluida u polimernoj mreži. Testovi antibakterijske aktivnosti su pokazali zadovoljavajuća antibakterijska svojstva biomaterijala u odnosu na soj bakterija Escherichia coli.",
publisher = "Association of Chemical Engineers of Serbia",
journal = "Hemijska industrija",
title = "Silver(I)-complexes with an itaconic acid-based hydrogel, Kompleksi srebra I kopolimernih hidrogelova na bazi itakonske kiseline",
pages = "142-137",
number = "3",
volume = "63",
doi = "10.2298/HEMIND0903137M"
}

Mićić, M. M., Tomić, S., Filipović, J. M.,& Suljovrujić, E. H.. (2009). Silver(I)-complexes with an itaconic acid-based hydrogel. in Hemijska industrija
Association of Chemical Engineers of Serbia., 63(3), 137-142.
https://doi.org/10.2298/HEMIND0903137M

Mićić MM, Tomić S, Filipović JM, Suljovrujić EH. Silver(I)-complexes with an itaconic acid-based hydrogel. in Hemijska industrija. 2009;63(3):137-142.
doi:10.2298/HEMIND0903137M .

Mićić, Maja M., Tomić, Simonida, Filipović, Jovanka M., Suljovrujić, Edin H., "Silver(I)-complexes with an itaconic acid-based hydrogel" in Hemijska industrija, 63, no. 3 (2009):137-142,
https://doi.org/10.2298/HEMIND0903137M . .

TY  - JOUR
AU  - Tomić, Simonida
AU  - Mićić, Maja M.
AU  - Dokić, D.
AU  - Vasiljević-Radović, Dana
AU  - Filipović, Jovanka M.
AU  - Suljovrujić, Edin H.
PY  - 2009
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/1527
AB  - Silver(I) complexes based on itaconic acid hydrogel were prepared and characterized in order to examine the potential use of these materials. FTIR, AFM, in vitro fluid-uptake, metal sorption, and antibacterial activity assay measurements were used for the characterization. Silver(I) ion uptake by hydrogels based on 2-hydroxyethyl methacrylate (HEMA), ethylene glycol dimethacrylate (EGDMA), and different content of itaconic acid (2; 3.5; 5mol%) were determined by inductively coupled plasma mass spectrometry. The coordination sites for metal ions were identified, and the stability in in-vitro condition was determined. Incorporation of silver(I) ions into hydrogels and the influence of these ions on material diffusion properties were analyzed. It was found that the itaconic acid moiety is the determining factor which influences metal ion binding and, therefore, fluid uptake inside the polymer network. Furthermore, obtained hydrogels showed a satisfactory antibacterial activity.
PB  - Taylor & Francis Inc, Philadelphia
T2  - Materials and Manufacturing Processes
T1  - Preparation of Silver(I) Complexes with Itaconic Acid-Based Hydrogels for Biomedical Application
EP  - 1201
IS  - 10-11
SP  - 1197
VL  - 24
DO  - 10.1080/10426910903022247
ER  - 

@article{
author = "Tomić, Simonida and Mićić, Maja M. and Dokić, D. and Vasiljević-Radović, Dana and Filipović, Jovanka M. and Suljovrujić, Edin H.",
year = "2009",
abstract = "Silver(I) complexes based on itaconic acid hydrogel were prepared and characterized in order to examine the potential use of these materials. FTIR, AFM, in vitro fluid-uptake, metal sorption, and antibacterial activity assay measurements were used for the characterization. Silver(I) ion uptake by hydrogels based on 2-hydroxyethyl methacrylate (HEMA), ethylene glycol dimethacrylate (EGDMA), and different content of itaconic acid (2; 3.5; 5mol%) were determined by inductively coupled plasma mass spectrometry. The coordination sites for metal ions were identified, and the stability in in-vitro condition was determined. Incorporation of silver(I) ions into hydrogels and the influence of these ions on material diffusion properties were analyzed. It was found that the itaconic acid moiety is the determining factor which influences metal ion binding and, therefore, fluid uptake inside the polymer network. Furthermore, obtained hydrogels showed a satisfactory antibacterial activity.",
publisher = "Taylor & Francis Inc, Philadelphia",
journal = "Materials and Manufacturing Processes",
title = "Preparation of Silver(I) Complexes with Itaconic Acid-Based Hydrogels for Biomedical Application",
pages = "1201-1197",
number = "10-11",
volume = "24",
doi = "10.1080/10426910903022247"
}

Tomić, S., Mićić, M. M., Dokić, D., Vasiljević-Radović, D., Filipović, J. M.,& Suljovrujić, E. H.. (2009). Preparation of Silver(I) Complexes with Itaconic Acid-Based Hydrogels for Biomedical Application. in Materials and Manufacturing Processes
Taylor & Francis Inc, Philadelphia., 24(10-11), 1197-1201.
https://doi.org/10.1080/10426910903022247

Tomić S, Mićić MM, Dokić D, Vasiljević-Radović D, Filipović JM, Suljovrujić EH. Preparation of Silver(I) Complexes with Itaconic Acid-Based Hydrogels for Biomedical Application. in Materials and Manufacturing Processes. 2009;24(10-11):1197-1201.
doi:10.1080/10426910903022247 .

Tomić, Simonida, Mićić, Maja M., Dokić, D., Vasiljević-Radović, Dana, Filipović, Jovanka M., Suljovrujić, Edin H., "Preparation of Silver(I) Complexes with Itaconic Acid-Based Hydrogels for Biomedical Application" in Materials and Manufacturing Processes, 24, no. 10-11 (2009):1197-1201,
https://doi.org/10.1080/10426910903022247 . .

TY  - JOUR
AU  - Suljovrujić, Edin H.
AU  - Ignjatović, Nenad
AU  - Uskoković, Dragan
AU  - Mitrić, Miodrag
AU  - Mitrovic, M.
AU  - Tomić, Simonida
PY  - 2007
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/5495
AB  - The effects of gamma irradiation on the structure and properties of hydroxyapatite/poly L-lactide (HAp/PLLA) biomaterial have been investigated. Effects of radiation on microstructure, degradation of polymer part and thermal stability of composite were determined by scanning electronic microscopy (SEM), gel permeation chromatography (GPC) and thermogravimetric analysis (TGA), respectively. Mechanical properties were obtained through mechanical strength and elasticity modulus. Presented results show that properties of HAp/PLLA decay with irradiation dose, but for doses required for sterilization, changes and damaging effects are acceptable. (C) 2006 Elsevier Ltd. All rights reserved.
T2  - Radiation Physics and Chemistry
T1  - Radiation-induced degradation of hydroxyapatite/poly L-lactide composite biomaterial
EP  - 728
IS  - 4
SP  - 722
VL  - 76
DO  - 10.1016/j.radphyschem.2006.02.013
UR  - https://hdl.handle.net/21.15107/rcub_dais_2752
ER  - 

@article{
author = "Suljovrujić, Edin H. and Ignjatović, Nenad and Uskoković, Dragan and Mitrić, Miodrag and Mitrovic, M. and Tomić, Simonida",
year = "2007",
abstract = "The effects of gamma irradiation on the structure and properties of hydroxyapatite/poly L-lactide (HAp/PLLA) biomaterial have been investigated. Effects of radiation on microstructure, degradation of polymer part and thermal stability of composite were determined by scanning electronic microscopy (SEM), gel permeation chromatography (GPC) and thermogravimetric analysis (TGA), respectively. Mechanical properties were obtained through mechanical strength and elasticity modulus. Presented results show that properties of HAp/PLLA decay with irradiation dose, but for doses required for sterilization, changes and damaging effects are acceptable. (C) 2006 Elsevier Ltd. All rights reserved.",
journal = "Radiation Physics and Chemistry",
title = "Radiation-induced degradation of hydroxyapatite/poly L-lactide composite biomaterial",
pages = "728-722",
number = "4",
volume = "76",
doi = "10.1016/j.radphyschem.2006.02.013",
url = "https://hdl.handle.net/21.15107/rcub_dais_2752"
}

Suljovrujić, E. H., Ignjatović, N., Uskoković, D., Mitrić, M., Mitrovic, M.,& Tomić, S.. (2007). Radiation-induced degradation of hydroxyapatite/poly L-lactide composite biomaterial. in Radiation Physics and Chemistry, 76(4), 722-728.
https://doi.org/10.1016/j.radphyschem.2006.02.013
https://hdl.handle.net/21.15107/rcub_dais_2752

Suljovrujić EH, Ignjatović N, Uskoković D, Mitrić M, Mitrovic M, Tomić S. Radiation-induced degradation of hydroxyapatite/poly L-lactide composite biomaterial. in Radiation Physics and Chemistry. 2007;76(4):722-728.
doi:10.1016/j.radphyschem.2006.02.013
https://hdl.handle.net/21.15107/rcub_dais_2752 .

Suljovrujić, Edin H., Ignjatović, Nenad, Uskoković, Dragan, Mitrić, Miodrag, Mitrovic, M., Tomić, Simonida, "Radiation-induced degradation of hydroxyapatite/poly L-lactide composite biomaterial" in Radiation Physics and Chemistry, 76, no. 4 (2007):722-728,
https://doi.org/10.1016/j.radphyschem.2006.02.013 .,
https://hdl.handle.net/21.15107/rcub_dais_2752 .

TY  - JOUR
AU  - Tomić, Simonida
AU  - Mićić, Maja M.
AU  - Filipović, Jovanka M.
AU  - Suljovrujić, Edin H.
PY  - 2007
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/1156
AB  - The copolymeric hydrogels based on 2-hydroxyethyl methacrylate (HEMA) and itaconic acid (IA) were synthesized by gamma radiation induced radical polymerization. Swelling and thermodynamic properties of PHEMA and copolymeric P(HEMA/IA) hydrogels with different IA contents (2, 3.5 and 5 mol%) were studied in a wide pH and temperature range. Initial studies of so-prepared hydrogels show interesting pH and temperature sensitivity in swelling and drug release behavior. Special attention was devoted to temperature investigations around physiological temperature (37 degrees C), where small changes in temperature significantly influence swelling and drug release of these hydrogels. Due to maximum swelling of hydrogels around 40 degrees C, the P(HEMA/IA) hydrogel containing 5mol% of IA without and with drug-antibiotic (gentamicin) were investigated at pH 7.40 and in the temperature range 25-42 degrees C, in order to evaluate their potential for medical applications.
PB  - Pergamon-Elsevier Science Ltd, Oxford
T2  - Radiation Physics and Chemistry
T1  - Swelling and thermodynamic studies of temperature responsive 2-hydroxyethyl methacrylate/itaconic acid copolymeric hydrogels prepared via gamma radiation
EP  - 1394
IS  - 8-9
SP  - 1390
VL  - 76
DO  - 10.1016/j.radphyschem.2007.02.038
ER  - 

@article{
author = "Tomić, Simonida and Mićić, Maja M. and Filipović, Jovanka M. and Suljovrujić, Edin H.",
year = "2007",
abstract = "The copolymeric hydrogels based on 2-hydroxyethyl methacrylate (HEMA) and itaconic acid (IA) were synthesized by gamma radiation induced radical polymerization. Swelling and thermodynamic properties of PHEMA and copolymeric P(HEMA/IA) hydrogels with different IA contents (2, 3.5 and 5 mol%) were studied in a wide pH and temperature range. Initial studies of so-prepared hydrogels show interesting pH and temperature sensitivity in swelling and drug release behavior. Special attention was devoted to temperature investigations around physiological temperature (37 degrees C), where small changes in temperature significantly influence swelling and drug release of these hydrogels. Due to maximum swelling of hydrogels around 40 degrees C, the P(HEMA/IA) hydrogel containing 5mol% of IA without and with drug-antibiotic (gentamicin) were investigated at pH 7.40 and in the temperature range 25-42 degrees C, in order to evaluate their potential for medical applications.",
publisher = "Pergamon-Elsevier Science Ltd, Oxford",
journal = "Radiation Physics and Chemistry",
title = "Swelling and thermodynamic studies of temperature responsive 2-hydroxyethyl methacrylate/itaconic acid copolymeric hydrogels prepared via gamma radiation",
pages = "1394-1390",
number = "8-9",
volume = "76",
doi = "10.1016/j.radphyschem.2007.02.038"
}

Tomić, S., Mićić, M. M., Filipović, J. M.,& Suljovrujić, E. H.. (2007). Swelling and thermodynamic studies of temperature responsive 2-hydroxyethyl methacrylate/itaconic acid copolymeric hydrogels prepared via gamma radiation. in Radiation Physics and Chemistry
Pergamon-Elsevier Science Ltd, Oxford., 76(8-9), 1390-1394.
https://doi.org/10.1016/j.radphyschem.2007.02.038

Tomić S, Mićić MM, Filipović JM, Suljovrujić EH. Swelling and thermodynamic studies of temperature responsive 2-hydroxyethyl methacrylate/itaconic acid copolymeric hydrogels prepared via gamma radiation. in Radiation Physics and Chemistry. 2007;76(8-9):1390-1394.
doi:10.1016/j.radphyschem.2007.02.038 .

Tomić, Simonida, Mićić, Maja M., Filipović, Jovanka M., Suljovrujić, Edin H., "Swelling and thermodynamic studies of temperature responsive 2-hydroxyethyl methacrylate/itaconic acid copolymeric hydrogels prepared via gamma radiation" in Radiation Physics and Chemistry, 76, no. 8-9 (2007):1390-1394,
https://doi.org/10.1016/j.radphyschem.2007.02.038 . .

TY  - JOUR
AU  - Mićić, Maja M.
AU  - Tomić, Simonida
AU  - Filipović, Jovanka M.
AU  - Suljovrujić, Edin H.
PY  - 2007
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/1063
AB  - New types of hydrogels were prepared by the radical copolymerization of 2-hydroxyethyl methacrylate, itaconic acid and four different poly(alkylene glycol) (meth)acrylate components (Bisomers) in a water/ethanol mixture as solvent. The polymers swell in water at 25°C to yield homogeneous transparent hydrogels. All the hydrogels displayed pH sensitive behavior in buffers of the pH range from 2.20 to 7.40, under conditions similar to those of biological fluids. The presence of these two comonomers, which were added to HEMA, increased the swelling degree of the hydrogels and gave gels with better elasticity. The hydrogels were thermally stable in the vicinity of the physiological temperature (37°C). The copolymer containing pure poly(ethylene glycol) acrylate units generally had the best properties. The tests performed on the hydrogels confirmed that they were neither hemolytic nor cytotoxic. The copolymer samples showed better cell viability and less hemolytic activity than the PHEMA sample, confirming the assumption that poly(alkylene glycols) improve the biocompatibility of hydrogels. Due to their swelling and mechanical characteristics, as well as the very good biocompatibility and bioadhesive properties, poly(Bisomer/HEMA/IA) hydrogels are promising for utilization in the field of biomedicals, especially for the controlled release of drugs.
AB  - Radikalnom kopolimerizacijom 2-hidroksietil metakrilata (HEMA), itakonske kiseline (IK) i četiri tipa poli(alkilen glikol) (met)akrilata (Bisomera-BIS) dobijeni su novi poli(BIS/HEMA/IK) hidrogelovi, u smeši voda/etanol kao rastvaraču. Ispitan je uticaj tipa Bisomera na bubrenje u puferima pH 2,20-7,40, u uslovima sličnim biološkim fluidima. Takođe, praćenje i uticaj na mehanička svojstva, morfologiju i termičko ponašanje dobijenih gelova. Testiranje biokompatibilnosti in vitro napoli (BIS/HEMA/IK) hidrogelovima pokazuje da nema ćelijske toksičnosti, niti hemolitičke aktivnosti. Gelovi poseduju zadovoljavajuću bioadhezivnost.
PB  - Association of Chemical Engineers of Serbia
T2  - Hemijska industrija
T1  - Biocompatible and bioadhesive hydrogels based on 2-hydroxyethyl methacrylate, monofunctional poly(alkylene glycol)s and itaconic acid
T1  - Biokompatibilni i bioadhezivni hidrogelovi na bazi 2-hidroksietil metakrilata, monofunkcionalizovanih poli(alkilen glikol)a i itakonske kiseline
EP  - 89
IS  - 2
SP  - 83
VL  - 61
DO  - 10.2298/HEMIND0702083M
ER  - 

@article{
author = "Mićić, Maja M. and Tomić, Simonida and Filipović, Jovanka M. and Suljovrujić, Edin H.",
year = "2007",
abstract = "New types of hydrogels were prepared by the radical copolymerization of 2-hydroxyethyl methacrylate, itaconic acid and four different poly(alkylene glycol) (meth)acrylate components (Bisomers) in a water/ethanol mixture as solvent. The polymers swell in water at 25°C to yield homogeneous transparent hydrogels. All the hydrogels displayed pH sensitive behavior in buffers of the pH range from 2.20 to 7.40, under conditions similar to those of biological fluids. The presence of these two comonomers, which were added to HEMA, increased the swelling degree of the hydrogels and gave gels with better elasticity. The hydrogels were thermally stable in the vicinity of the physiological temperature (37°C). The copolymer containing pure poly(ethylene glycol) acrylate units generally had the best properties. The tests performed on the hydrogels confirmed that they were neither hemolytic nor cytotoxic. The copolymer samples showed better cell viability and less hemolytic activity than the PHEMA sample, confirming the assumption that poly(alkylene glycols) improve the biocompatibility of hydrogels. Due to their swelling and mechanical characteristics, as well as the very good biocompatibility and bioadhesive properties, poly(Bisomer/HEMA/IA) hydrogels are promising for utilization in the field of biomedicals, especially for the controlled release of drugs., Radikalnom kopolimerizacijom 2-hidroksietil metakrilata (HEMA), itakonske kiseline (IK) i četiri tipa poli(alkilen glikol) (met)akrilata (Bisomera-BIS) dobijeni su novi poli(BIS/HEMA/IK) hidrogelovi, u smeši voda/etanol kao rastvaraču. Ispitan je uticaj tipa Bisomera na bubrenje u puferima pH 2,20-7,40, u uslovima sličnim biološkim fluidima. Takođe, praćenje i uticaj na mehanička svojstva, morfologiju i termičko ponašanje dobijenih gelova. Testiranje biokompatibilnosti in vitro napoli (BIS/HEMA/IK) hidrogelovima pokazuje da nema ćelijske toksičnosti, niti hemolitičke aktivnosti. Gelovi poseduju zadovoljavajuću bioadhezivnost.",
publisher = "Association of Chemical Engineers of Serbia",
journal = "Hemijska industrija",
title = "Biocompatible and bioadhesive hydrogels based on 2-hydroxyethyl methacrylate, monofunctional poly(alkylene glycol)s and itaconic acid, Biokompatibilni i bioadhezivni hidrogelovi na bazi 2-hidroksietil metakrilata, monofunkcionalizovanih poli(alkilen glikol)a i itakonske kiseline",
pages = "89-83",
number = "2",
volume = "61",
doi = "10.2298/HEMIND0702083M"
}

Mićić, M. M., Tomić, S., Filipović, J. M.,& Suljovrujić, E. H.. (2007). Biocompatible and bioadhesive hydrogels based on 2-hydroxyethyl methacrylate, monofunctional poly(alkylene glycol)s and itaconic acid. in Hemijska industrija
Association of Chemical Engineers of Serbia., 61(2), 83-89.
https://doi.org/10.2298/HEMIND0702083M

Mićić MM, Tomić S, Filipović JM, Suljovrujić EH. Biocompatible and bioadhesive hydrogels based on 2-hydroxyethyl methacrylate, monofunctional poly(alkylene glycol)s and itaconic acid. in Hemijska industrija. 2007;61(2):83-89.
doi:10.2298/HEMIND0702083M .

Mićić, Maja M., Tomić, Simonida, Filipović, Jovanka M., Suljovrujić, Edin H., "Biocompatible and bioadhesive hydrogels based on 2-hydroxyethyl methacrylate, monofunctional poly(alkylene glycol)s and itaconic acid" in Hemijska industrija, 61, no. 2 (2007):83-89,
https://doi.org/10.2298/HEMIND0702083M . .

TY  - JOUR
AU  - Mićić, Maja M.
AU  - Tomić, Simonida
AU  - Filipović, Jovanka M.
AU  - Suljovrujić, Edin H.
PY  - 2007
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/1019
AB  - Controlled release studies of drugs (theophylline (TH), fenethylline hydrochloride (FE) and gentamicin sulphate (GS)) from pH sensitive poly(2-hydroxyethyl methacrylate/itaconic acid) (P(HEMA/IA)) hydrogels obtained by gamma irradiation were carried out to investigate transport phenomena. Drug behavior and release profiles were analyzed using the restriction coefficient combining the influence of network structure and the size of the drug on release and transport properties. The results demonstrated that the ratio of drug radius to polymer pore size and drugpolymer interactions were dominant factors in hindering the diffusion process. The diffusivity of a drug through the hydrogels decreases with the size of the drug molecules and with the decrease in gel pore size. The diffusion equations for used drugs explain drug transport in hydrogels.
PB  - 8th Conference of the Yugoslav Materials Research Society
T2  - Materials Science Forum
T1  - Release and diffusion studies of hydrogels based on itaconic acid
EP  - 446
SP  - 441
VL  - 555
DO  - 10.4028/0-87849-441-3.441
ER  - 

@article{
author = "Mićić, Maja M. and Tomić, Simonida and Filipović, Jovanka M. and Suljovrujić, Edin H.",
year = "2007",
abstract = "Controlled release studies of drugs (theophylline (TH), fenethylline hydrochloride (FE) and gentamicin sulphate (GS)) from pH sensitive poly(2-hydroxyethyl methacrylate/itaconic acid) (P(HEMA/IA)) hydrogels obtained by gamma irradiation were carried out to investigate transport phenomena. Drug behavior and release profiles were analyzed using the restriction coefficient combining the influence of network structure and the size of the drug on release and transport properties. The results demonstrated that the ratio of drug radius to polymer pore size and drugpolymer interactions were dominant factors in hindering the diffusion process. The diffusivity of a drug through the hydrogels decreases with the size of the drug molecules and with the decrease in gel pore size. The diffusion equations for used drugs explain drug transport in hydrogels.",
publisher = "8th Conference of the Yugoslav Materials Research Society",
journal = "Materials Science Forum",
title = "Release and diffusion studies of hydrogels based on itaconic acid",
pages = "446-441",
volume = "555",
doi = "10.4028/0-87849-441-3.441"
}

Mićić, M. M., Tomić, S., Filipović, J. M.,& Suljovrujić, E. H.. (2007). Release and diffusion studies of hydrogels based on itaconic acid. in Materials Science Forum
8th Conference of the Yugoslav Materials Research Society., 555, 441-446.
https://doi.org/10.4028/0-87849-441-3.441

Mićić MM, Tomić S, Filipović JM, Suljovrujić EH. Release and diffusion studies of hydrogels based on itaconic acid. in Materials Science Forum. 2007;555:441-446.
doi:10.4028/0-87849-441-3.441 .

Mićić, Maja M., Tomić, Simonida, Filipović, Jovanka M., Suljovrujić, Edin H., "Release and diffusion studies of hydrogels based on itaconic acid" in Materials Science Forum, 555 (2007):441-446,
https://doi.org/10.4028/0-87849-441-3.441 . .

TY  - JOUR
AU  - Tomić, Simonida
AU  - Mićić, Maja M.
AU  - Filipović, Jovanka M.
AU  - Suljovrujić, Edin H.
PY  - 2007
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/1085
AB  - The new copolymeric hydrogels based on 2-hydroxyethyl methacrylate (HEMA) and itaconic acid (IA) were prepared by gamma irradiation, in order to examine the potential use of these hydrogels in controlled drug release systems. The influence of IA content in the gel on the swelling characteristics and the releasing behavior of hydrogels, and the effect of different drugs, theophylline (TPH) and fenethylline hydrochloride (FE), on the releasing behavior of P(HEMA/IA) matrix were investigated in vitro. The diffusion exponents for swelling and drug release indicate that the mechanisms of buffer uptake and drug release are governed by Fickian diffusion. The swelling kinetics and, therefore, the release rate depends on the matrix swelling degree. The drug release was faster for copolymeric hydrogels with a higher content of itaconic acid. Furthermore, the drug release for TPH as model drug was faster due to a smaller molecular size and a weaker interaction of the TPH molecules with(in) the P(HEMA/IA) copolymeric networks.
PB  - Pergamon-Elsevier Science Ltd, Oxford
T2  - Radiation Physics and Chemistry
T1  - Swelling and drug release behavior of poly(2-hydroxyethyl methacrylate/itaconic acid) copolymeric hydrogels obtained by gamma irradiation
EP  - 810
IS  - 5
SP  - 801
VL  - 76
DO  - 10.1016/j.radphyschem.2006.05.013
ER  - 

@article{
author = "Tomić, Simonida and Mićić, Maja M. and Filipović, Jovanka M. and Suljovrujić, Edin H.",
year = "2007",
abstract = "The new copolymeric hydrogels based on 2-hydroxyethyl methacrylate (HEMA) and itaconic acid (IA) were prepared by gamma irradiation, in order to examine the potential use of these hydrogels in controlled drug release systems. The influence of IA content in the gel on the swelling characteristics and the releasing behavior of hydrogels, and the effect of different drugs, theophylline (TPH) and fenethylline hydrochloride (FE), on the releasing behavior of P(HEMA/IA) matrix were investigated in vitro. The diffusion exponents for swelling and drug release indicate that the mechanisms of buffer uptake and drug release are governed by Fickian diffusion. The swelling kinetics and, therefore, the release rate depends on the matrix swelling degree. The drug release was faster for copolymeric hydrogels with a higher content of itaconic acid. Furthermore, the drug release for TPH as model drug was faster due to a smaller molecular size and a weaker interaction of the TPH molecules with(in) the P(HEMA/IA) copolymeric networks.",
publisher = "Pergamon-Elsevier Science Ltd, Oxford",
journal = "Radiation Physics and Chemistry",
title = "Swelling and drug release behavior of poly(2-hydroxyethyl methacrylate/itaconic acid) copolymeric hydrogels obtained by gamma irradiation",
pages = "810-801",
number = "5",
volume = "76",
doi = "10.1016/j.radphyschem.2006.05.013"
}

Tomić, S., Mićić, M. M., Filipović, J. M.,& Suljovrujić, E. H.. (2007). Swelling and drug release behavior of poly(2-hydroxyethyl methacrylate/itaconic acid) copolymeric hydrogels obtained by gamma irradiation. in Radiation Physics and Chemistry
Pergamon-Elsevier Science Ltd, Oxford., 76(5), 801-810.
https://doi.org/10.1016/j.radphyschem.2006.05.013

Tomić S, Mićić MM, Filipović JM, Suljovrujić EH. Swelling and drug release behavior of poly(2-hydroxyethyl methacrylate/itaconic acid) copolymeric hydrogels obtained by gamma irradiation. in Radiation Physics and Chemistry. 2007;76(5):801-810.
doi:10.1016/j.radphyschem.2006.05.013 .

Tomić, Simonida, Mićić, Maja M., Filipović, Jovanka M., Suljovrujić, Edin H., "Swelling and drug release behavior of poly(2-hydroxyethyl methacrylate/itaconic acid) copolymeric hydrogels obtained by gamma irradiation" in Radiation Physics and Chemistry, 76, no. 5 (2007):801-810,
https://doi.org/10.1016/j.radphyschem.2006.05.013 . .

TY  - JOUR
AU  - Tomić, Simonida
AU  - Mićić, Maja M.
AU  - Vukašinović-Milić, Tatjana
AU  - Marinković, Aleksandar
AU  - Suljovrujić, Edin H.
AU  - Filipović, Jovanka
PY  - 2006
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/926
AB  - The new copolymeric hydrogels based on 2-hydroxyethyl methacrylate (HEMA) and itaconic acid (IA) were prepared by gamma irradiation, in order to examine the potential use of these hydrogels in controlled drug release systems. The influence of IA content in the gel on the swelling characteristics and the releasing behavior of hydrogels, and the effect of different drugs theophylline (TPH) and fenethylline hydrochloride (FE), on the releasing behavior of P(HEMA/IA) matrix were investigated in vitro. The diffusion exponents for swelling and drug release indicate that the mechanisms of buffer uptake and drug release are governed by Fickian diffusion. The swelling kinetics and, therefore, the release rate depends on the matrix swelling degree. The drug release was faster for copolymeric hydrogels with a higher content of itaconic acid. Furthermore, the drug release for theophylline as model drug was faster due to a smaller molecular size and a weaker interaction of the TPH molecules with(in) the P(HEMA/IA) copolymeric networks.
AB  - Novi kopolimerni hidrogelovi na bazi 2-hidroksietil metakrilata (HEMA) i itakonske kiseline (IK) su dobijeni gama ozračivanjem, u cilju ispitivanja njihove potencijalne primene u sistemima za kontrolisano otpuštanje aktivnih materija. Ispitan je uticaj sadržaja IK u P(HEMA/IK) hidrogelovima na bubrenje i sposobnost otpuštanja aktivnih materija, kao i uticaj različitih lekova - teofilina (TF) i fenetilin hidrohlorida (FE) na profil otpuštanja iz P(HEMA/IK) gelova, u in vitro uslovima. Difuzioni eksponenti bubrenja i otpuštanja lekovitih supstanci pokazuju da se mehanizmi upijanja pufera, kao i otpuštanja lekovitih supstanci mogu opisati Fikovim zakonom difuzije. Prema tome, kinetika bubrenja i brzina otpuštanja zavise od stepena bubrenja gelova. Kopolimerni hidrogelovi sa većim sadržajem itakonske kiseline brže otpuštaju lekove. Teofilin se brže otpušta iz gelova u odnosu na fenetilin hidrohlorid, jer je u pitanju molekul manje molske mase, kao i postojanje slabijih interakcija molekula TF sa P(HEMA/IK) kopolimerima.
PB  - Savez inženjera i tehničara Srbije, Beograd
T2  - Tehnika - Novi materijali
T1  - Swelling and drug release behavior of poly(2-hydroxyethyl methacrylate/itaconic acid) copolymeric hydrogels obtained by gamma irradiation
T1  - Bubrenje i kontrolisano otpuštanje aktivnih materija iz poli(2-hidroksietil metakrilat/itakonska kiselina) kopolimernih hidrogelova dobijenih gama ozračivanjem
EP  - 22
IS  - 4
SP  - 15
VL  - 15
UR  - https://hdl.handle.net/21.15107/rcub_technorep_926
ER  - 

@article{
author = "Tomić, Simonida and Mićić, Maja M. and Vukašinović-Milić, Tatjana and Marinković, Aleksandar and Suljovrujić, Edin H. and Filipović, Jovanka",
year = "2006",
abstract = "The new copolymeric hydrogels based on 2-hydroxyethyl methacrylate (HEMA) and itaconic acid (IA) were prepared by gamma irradiation, in order to examine the potential use of these hydrogels in controlled drug release systems. The influence of IA content in the gel on the swelling characteristics and the releasing behavior of hydrogels, and the effect of different drugs theophylline (TPH) and fenethylline hydrochloride (FE), on the releasing behavior of P(HEMA/IA) matrix were investigated in vitro. The diffusion exponents for swelling and drug release indicate that the mechanisms of buffer uptake and drug release are governed by Fickian diffusion. The swelling kinetics and, therefore, the release rate depends on the matrix swelling degree. The drug release was faster for copolymeric hydrogels with a higher content of itaconic acid. Furthermore, the drug release for theophylline as model drug was faster due to a smaller molecular size and a weaker interaction of the TPH molecules with(in) the P(HEMA/IA) copolymeric networks., Novi kopolimerni hidrogelovi na bazi 2-hidroksietil metakrilata (HEMA) i itakonske kiseline (IK) su dobijeni gama ozračivanjem, u cilju ispitivanja njihove potencijalne primene u sistemima za kontrolisano otpuštanje aktivnih materija. Ispitan je uticaj sadržaja IK u P(HEMA/IK) hidrogelovima na bubrenje i sposobnost otpuštanja aktivnih materija, kao i uticaj različitih lekova - teofilina (TF) i fenetilin hidrohlorida (FE) na profil otpuštanja iz P(HEMA/IK) gelova, u in vitro uslovima. Difuzioni eksponenti bubrenja i otpuštanja lekovitih supstanci pokazuju da se mehanizmi upijanja pufera, kao i otpuštanja lekovitih supstanci mogu opisati Fikovim zakonom difuzije. Prema tome, kinetika bubrenja i brzina otpuštanja zavise od stepena bubrenja gelova. Kopolimerni hidrogelovi sa većim sadržajem itakonske kiseline brže otpuštaju lekove. Teofilin se brže otpušta iz gelova u odnosu na fenetilin hidrohlorid, jer je u pitanju molekul manje molske mase, kao i postojanje slabijih interakcija molekula TF sa P(HEMA/IK) kopolimerima.",
publisher = "Savez inženjera i tehničara Srbije, Beograd",
journal = "Tehnika - Novi materijali",
title = "Swelling and drug release behavior of poly(2-hydroxyethyl methacrylate/itaconic acid) copolymeric hydrogels obtained by gamma irradiation, Bubrenje i kontrolisano otpuštanje aktivnih materija iz poli(2-hidroksietil metakrilat/itakonska kiselina) kopolimernih hidrogelova dobijenih gama ozračivanjem",
pages = "22-15",
number = "4",
volume = "15",
url = "https://hdl.handle.net/21.15107/rcub_technorep_926"
}

Tomić, S., Mićić, M. M., Vukašinović-Milić, T., Marinković, A., Suljovrujić, E. H.,& Filipović, J.. (2006). Swelling and drug release behavior of poly(2-hydroxyethyl methacrylate/itaconic acid) copolymeric hydrogels obtained by gamma irradiation. in Tehnika - Novi materijali
Savez inženjera i tehničara Srbije, Beograd., 15(4), 15-22.
https://hdl.handle.net/21.15107/rcub_technorep_926

Tomić S, Mićić MM, Vukašinović-Milić T, Marinković A, Suljovrujić EH, Filipović J. Swelling and drug release behavior of poly(2-hydroxyethyl methacrylate/itaconic acid) copolymeric hydrogels obtained by gamma irradiation. in Tehnika - Novi materijali. 2006;15(4):15-22.
https://hdl.handle.net/21.15107/rcub_technorep_926 .

Tomić, Simonida, Mićić, Maja M., Vukašinović-Milić, Tatjana, Marinković, Aleksandar, Suljovrujić, Edin H., Filipović, Jovanka, "Swelling and drug release behavior of poly(2-hydroxyethyl methacrylate/itaconic acid) copolymeric hydrogels obtained by gamma irradiation" in Tehnika - Novi materijali, 15, no. 4 (2006):15-22,
https://hdl.handle.net/21.15107/rcub_technorep_926 .

TY  - JOUR
AU  - Tomić, Simonida
AU  - Suljovrujić, Edin H.
AU  - Filipović, Jovanka M.
PY  - 2006
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/961
AB  - Novel poly(Bisomer/HEMA/IA) hydrogels were prepared by radical copolymerization of poly(alkylene glycol) (meth)acrylates, i.e. short chains Bisomers, 2-hydroxyethyl methacrylate (HEMA) and itaconic acid (IA) in a mixture of water/ethanol as solvent. These hydrogels were characterized in terms of swelling in conditions similar to the biological fluids (pH range 2.20-7.40 buffer solutions), compression-strain measurements, thermal properties and morphology. The influence of the type of Bisomer and of the itaconic acid on swelling and mechanical properties, as well as on morphology and thermal behavior of the resulting hydrogels, were investigated. The in vitro study of biocompatibility, carried out with the hydrogels containing different types of Bisomers, showed no evidence of cell toxicity nor any considerable hemolytic activity. All hydrogels showed satisfactory bioadhesive properties, so these materials have potential as drug carriers or biological glue and sealants.
PB  - Springer, New York
T2  - Polymer Bulletin
T1  - Biocompatible and bioadhesive hydrogels based on 2-hydroxyethyl methacrylate, monofunctional poly(alkylene glycol)s and itaconic acid
EP  - 702
IS  - 5
SP  - 691
VL  - 57
DO  - 10.1007/s00289-006-0606-3
ER  - 

@article{
author = "Tomić, Simonida and Suljovrujić, Edin H. and Filipović, Jovanka M.",
year = "2006",
abstract = "Novel poly(Bisomer/HEMA/IA) hydrogels were prepared by radical copolymerization of poly(alkylene glycol) (meth)acrylates, i.e. short chains Bisomers, 2-hydroxyethyl methacrylate (HEMA) and itaconic acid (IA) in a mixture of water/ethanol as solvent. These hydrogels were characterized in terms of swelling in conditions similar to the biological fluids (pH range 2.20-7.40 buffer solutions), compression-strain measurements, thermal properties and morphology. The influence of the type of Bisomer and of the itaconic acid on swelling and mechanical properties, as well as on morphology and thermal behavior of the resulting hydrogels, were investigated. The in vitro study of biocompatibility, carried out with the hydrogels containing different types of Bisomers, showed no evidence of cell toxicity nor any considerable hemolytic activity. All hydrogels showed satisfactory bioadhesive properties, so these materials have potential as drug carriers or biological glue and sealants.",
publisher = "Springer, New York",
journal = "Polymer Bulletin",
title = "Biocompatible and bioadhesive hydrogels based on 2-hydroxyethyl methacrylate, monofunctional poly(alkylene glycol)s and itaconic acid",
pages = "702-691",
number = "5",
volume = "57",
doi = "10.1007/s00289-006-0606-3"
}

Tomić, S., Suljovrujić, E. H.,& Filipović, J. M.. (2006). Biocompatible and bioadhesive hydrogels based on 2-hydroxyethyl methacrylate, monofunctional poly(alkylene glycol)s and itaconic acid. in Polymer Bulletin
Springer, New York., 57(5), 691-702.
https://doi.org/10.1007/s00289-006-0606-3

Tomić S, Suljovrujić EH, Filipović JM. Biocompatible and bioadhesive hydrogels based on 2-hydroxyethyl methacrylate, monofunctional poly(alkylene glycol)s and itaconic acid. in Polymer Bulletin. 2006;57(5):691-702.
doi:10.1007/s00289-006-0606-3 .

Tomić, Simonida, Suljovrujić, Edin H., Filipović, Jovanka M., "Biocompatible and bioadhesive hydrogels based on 2-hydroxyethyl methacrylate, monofunctional poly(alkylene glycol)s and itaconic acid" in Polymer Bulletin, 57, no. 5 (2006):691-702,
https://doi.org/10.1007/s00289-006-0606-3 . .

TY  - JOUR
AU  - Vukašinović-Milić, Tatjana
AU  - Miličević, Dejan S.
AU  - Mićić, Maja M.
AU  - Trifunović, Saša
AU  - Suljovrujić, Edin H.
AU  - Tomić, Simonida
AU  - Ignjatović, Nenad
AU  - Uskoković, Dragan
PY  - 2006
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/925
AB  - The effects of gamma irradiation on the structure and properties of hydroxyapatite/poly- Llactide (HAp/PLLA) biomaterial have been investigated. Effects of radiation on microstructure, degradation of polymer part and thermal stability of composite were determined by scanning electronic microscopy (SEM), gel permeation chromatography (GPC) and thermogravimetric analysis (TGA), respectively. Mechanical properties were obtained through mechanical strength and elasticity modulus. Presented results show that properties of HAp/PLLA decay with irradiation dose, but for doses required for sterilization, changes and damaging effects are acceptable.
AB  - Ispitivan je uticaj γ-zračenja na strukturu i osobine hidroksiapatit/poli-L-laktida (Hap/PLLA). Uticaj zračenja na mikrostrukturu degradaciju polimera i termičku stabilanost kompozita određivani su skenirajućom elektronskom mikroskopijom (SEM), gel-propusnom hromatografijom (GPH) i termogravimetrijskom analizom (TGA), respektivno. Mehaničke osobine su određene na osnovu mehaničke čvrstoće i modula elastičnosti. Dobijeni rezultati pokazuju slabljenje osobina HAp/PLLA sa povećanjem doze zračenja. Za doze zračenja pri kojima se odvija sterilizacija, promene i efekti oštećenja su prihvatljivi.
PB  - Savez inženjera i tehničara Srbije, Beograd
T2  - Tehnika - Novi materijali
T1  - Sterilization of hydroxyapatite/poly-L-lactide composite biomaterial by gamma irradiation
T1  - Sterilizacija hidroksiapatit/poli-L-laktid kompozitnog biomaterijala dejstvom γ-zračenja
EP  - 14
IS  - 4
SP  - 9
VL  - 15
UR  - https://hdl.handle.net/21.15107/rcub_technorep_925
ER  - 

@article{
author = "Vukašinović-Milić, Tatjana and Miličević, Dejan S. and Mićić, Maja M. and Trifunović, Saša and Suljovrujić, Edin H. and Tomić, Simonida and Ignjatović, Nenad and Uskoković, Dragan",
year = "2006",
abstract = "The effects of gamma irradiation on the structure and properties of hydroxyapatite/poly- Llactide (HAp/PLLA) biomaterial have been investigated. Effects of radiation on microstructure, degradation of polymer part and thermal stability of composite were determined by scanning electronic microscopy (SEM), gel permeation chromatography (GPC) and thermogravimetric analysis (TGA), respectively. Mechanical properties were obtained through mechanical strength and elasticity modulus. Presented results show that properties of HAp/PLLA decay with irradiation dose, but for doses required for sterilization, changes and damaging effects are acceptable., Ispitivan je uticaj γ-zračenja na strukturu i osobine hidroksiapatit/poli-L-laktida (Hap/PLLA). Uticaj zračenja na mikrostrukturu degradaciju polimera i termičku stabilanost kompozita određivani su skenirajućom elektronskom mikroskopijom (SEM), gel-propusnom hromatografijom (GPH) i termogravimetrijskom analizom (TGA), respektivno. Mehaničke osobine su određene na osnovu mehaničke čvrstoće i modula elastičnosti. Dobijeni rezultati pokazuju slabljenje osobina HAp/PLLA sa povećanjem doze zračenja. Za doze zračenja pri kojima se odvija sterilizacija, promene i efekti oštećenja su prihvatljivi.",
publisher = "Savez inženjera i tehničara Srbije, Beograd",
journal = "Tehnika - Novi materijali",
title = "Sterilization of hydroxyapatite/poly-L-lactide composite biomaterial by gamma irradiation, Sterilizacija hidroksiapatit/poli-L-laktid kompozitnog biomaterijala dejstvom γ-zračenja",
pages = "14-9",
number = "4",
volume = "15",
url = "https://hdl.handle.net/21.15107/rcub_technorep_925"
}

Vukašinović-Milić, T., Miličević, D. S., Mićić, M. M., Trifunović, S., Suljovrujić, E. H., Tomić, S., Ignjatović, N.,& Uskoković, D.. (2006). Sterilization of hydroxyapatite/poly-L-lactide composite biomaterial by gamma irradiation. in Tehnika - Novi materijali
Savez inženjera i tehničara Srbije, Beograd., 15(4), 9-14.
https://hdl.handle.net/21.15107/rcub_technorep_925

Vukašinović-Milić T, Miličević DS, Mićić MM, Trifunović S, Suljovrujić EH, Tomić S, Ignjatović N, Uskoković D. Sterilization of hydroxyapatite/poly-L-lactide composite biomaterial by gamma irradiation. in Tehnika - Novi materijali. 2006;15(4):9-14.
https://hdl.handle.net/21.15107/rcub_technorep_925 .

Vukašinović-Milić, Tatjana, Miličević, Dejan S., Mićić, Maja M., Trifunović, Saša, Suljovrujić, Edin H., Tomić, Simonida, Ignjatović, Nenad, Uskoković, Dragan, "Sterilization of hydroxyapatite/poly-L-lactide composite biomaterial by gamma irradiation" in Tehnika - Novi materijali, 15, no. 4 (2006):9-14,
https://hdl.handle.net/21.15107/rcub_technorep_925 .

TY  - JOUR
AU  - Tomić, Simonida
AU  - Mićić, Maja M.
AU  - Filipović, Jovanka M.
AU  - Suljovrujić, Edin H.
PY  - 2005
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/720
AB  - Hydrogels based on 2-hydroxyethyl methacrylate and different types of poly(alkylene glycol) acrylates and methacrylates, with a small percent of itaconic acid, have been prepared by solution copolymerization using gamma irradiation. In this study, the swelling behavior and network parameters of these hydrogels as a function of poly(alkylene glycol) acrylate type are reported for the first time. Morphology of the obtained hydrogels was characterized using scanning electron microscopy (SEM) technique.
PB  - 6th Conference of the Yugoslav Materials Research Society, YUCOMAT VI: Current Research in Advanced Materials and Processes
T2  - Materials Science Forum
T1  - Hydrogels based on 2-hydroxyethyl methacrylate obtained by gamma irradiation
EP  - 204
SP  - 199
VL  - 494
DO  - 10.4028/0-87849-971-7.199
ER  - 

@article{
author = "Tomić, Simonida and Mićić, Maja M. and Filipović, Jovanka M. and Suljovrujić, Edin H.",
year = "2005",
abstract = "Hydrogels based on 2-hydroxyethyl methacrylate and different types of poly(alkylene glycol) acrylates and methacrylates, with a small percent of itaconic acid, have been prepared by solution copolymerization using gamma irradiation. In this study, the swelling behavior and network parameters of these hydrogels as a function of poly(alkylene glycol) acrylate type are reported for the first time. Morphology of the obtained hydrogels was characterized using scanning electron microscopy (SEM) technique.",
publisher = "6th Conference of the Yugoslav Materials Research Society, YUCOMAT VI: Current Research in Advanced Materials and Processes",
journal = "Materials Science Forum",
title = "Hydrogels based on 2-hydroxyethyl methacrylate obtained by gamma irradiation",
pages = "204-199",
volume = "494",
doi = "10.4028/0-87849-971-7.199"
}

Tomić, S., Mićić, M. M., Filipović, J. M.,& Suljovrujić, E. H.. (2005). Hydrogels based on 2-hydroxyethyl methacrylate obtained by gamma irradiation. in Materials Science Forum
6th Conference of the Yugoslav Materials Research Society, YUCOMAT VI: Current Research in Advanced Materials and Processes., 494, 199-204.
https://doi.org/10.4028/0-87849-971-7.199

Tomić S, Mićić MM, Filipović JM, Suljovrujić EH. Hydrogels based on 2-hydroxyethyl methacrylate obtained by gamma irradiation. in Materials Science Forum. 2005;494:199-204.
doi:10.4028/0-87849-971-7.199 .

Tomić, Simonida, Mićić, Maja M., Filipović, Jovanka M., Suljovrujić, Edin H., "Hydrogels based on 2-hydroxyethyl methacrylate obtained by gamma irradiation" in Materials Science Forum, 494 (2005):199-204,
https://doi.org/10.4028/0-87849-971-7.199 . .

TY  - JOUR
AU  - Tomić, Simonida
AU  - Mićić, Maja M.
AU  - Suljovrujić, Edin H.
AU  - Filipović, Jovanka M.
PY  - 2004
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/670
PB  - Association of Chemical Engineers of Serbia
T2  - Hemijska industrija
T1  - Copolymeric hydrogels based on poly(ethylene glycol) acrylate and 2-hydroxyethyl methacrylate obtained by gamma irradiation
EP  - 51
IS  - 6a
SP  - 49
VL  - 58
UR  - https://hdl.handle.net/21.15107/rcub_technorep_670
ER  - 

@article{
author = "Tomić, Simonida and Mićić, Maja M. and Suljovrujić, Edin H. and Filipović, Jovanka M.",
year = "2004",
publisher = "Association of Chemical Engineers of Serbia",
journal = "Hemijska industrija",
title = "Copolymeric hydrogels based on poly(ethylene glycol) acrylate and 2-hydroxyethyl methacrylate obtained by gamma irradiation",
pages = "51-49",
number = "6a",
volume = "58",
url = "https://hdl.handle.net/21.15107/rcub_technorep_670"
}

Tomić, S., Mićić, M. M., Suljovrujić, E. H.,& Filipović, J. M.. (2004). Copolymeric hydrogels based on poly(ethylene glycol) acrylate and 2-hydroxyethyl methacrylate obtained by gamma irradiation. in Hemijska industrija
Association of Chemical Engineers of Serbia., 58(6a), 49-51.
https://hdl.handle.net/21.15107/rcub_technorep_670

Tomić S, Mićić MM, Suljovrujić EH, Filipović JM. Copolymeric hydrogels based on poly(ethylene glycol) acrylate and 2-hydroxyethyl methacrylate obtained by gamma irradiation. in Hemijska industrija. 2004;58(6a):49-51.
https://hdl.handle.net/21.15107/rcub_technorep_670 .

Tomić, Simonida, Mićić, Maja M., Suljovrujić, Edin H., Filipović, Jovanka M., "Copolymeric hydrogels based on poly(ethylene glycol) acrylate and 2-hydroxyethyl methacrylate obtained by gamma irradiation" in Hemijska industrija, 58, no. 6a (2004):49-51,
https://hdl.handle.net/21.15107/rcub_technorep_670 .