TY  - JOUR
AU  - Rajilić-Stojanović, Mirjana
AU  - Jonkers, Daisy M.
AU  - Salonen, Anne
AU  - Hanevik, Kurt
AU  - Raes, Jeroen
AU  - Jalanka, Jonna
AU  - de Vos, Willem M.
AU  - Manichanh, Chaysavanh
AU  - Golić, Nataša
AU  - Enck, Paul
AU  - Philippou, Elena
AU  - Iraqi, Fuad A.
AU  - Clarke, Gerard
AU  - Spiller, Robin C.
AU  - Penders, John
PY  - 2015
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/2973
AB  - Irritable bowel syndrome (IBS) is a heterogeneous functional disorder with a multifactorial etiology that involves the interplay of both host and environmental factors. Among environmental factors relevant for IBS etiology, the diet stands out given that the majority of IBS patients report their symptoms to be triggered by meals or specifi c foods. The diet provides substrates for microbial fermentation, and, as the composition of the intestinal microbiota is disturbed in IBS patients, the link between diet, microbiota composition, and microbial fermentation products might have an essential role in IBS etiology. In this review, we summarize current evidence regarding the impact of diet and the intestinal microbiota on IBS symptoms, as well as the reported interactions between diet and the microbiota composition. On the basis of the existing data, we suggest pathways (mechanisms) by which diet components, via the microbial fermentation, could trigger IBS symptoms. Finally, this review provides recommendations for future studies that would enable elucidation of the role of diet and microbiota and how these factors may be (inter) related in the pathophysiology of IBS.
PB  - Lippincott Williams & Wilkins, Philadelphia
T2  - American Journal of Gastroenterology
T1  - Intestinal Microbiota And Diet in IBS: Causes, Consequences, or Epiphenomena?
EP  - 287
IS  - 2
SP  - 278
VL  - 110
DO  - 10.1038/ajg.2014.427
ER  - 

@article{
author = "Rajilić-Stojanović, Mirjana and Jonkers, Daisy M. and Salonen, Anne and Hanevik, Kurt and Raes, Jeroen and Jalanka, Jonna and de Vos, Willem M. and Manichanh, Chaysavanh and Golić, Nataša and Enck, Paul and Philippou, Elena and Iraqi, Fuad A. and Clarke, Gerard and Spiller, Robin C. and Penders, John",
year = "2015",
abstract = "Irritable bowel syndrome (IBS) is a heterogeneous functional disorder with a multifactorial etiology that involves the interplay of both host and environmental factors. Among environmental factors relevant for IBS etiology, the diet stands out given that the majority of IBS patients report their symptoms to be triggered by meals or specifi c foods. The diet provides substrates for microbial fermentation, and, as the composition of the intestinal microbiota is disturbed in IBS patients, the link between diet, microbiota composition, and microbial fermentation products might have an essential role in IBS etiology. In this review, we summarize current evidence regarding the impact of diet and the intestinal microbiota on IBS symptoms, as well as the reported interactions between diet and the microbiota composition. On the basis of the existing data, we suggest pathways (mechanisms) by which diet components, via the microbial fermentation, could trigger IBS symptoms. Finally, this review provides recommendations for future studies that would enable elucidation of the role of diet and microbiota and how these factors may be (inter) related in the pathophysiology of IBS.",
publisher = "Lippincott Williams & Wilkins, Philadelphia",
journal = "American Journal of Gastroenterology",
title = "Intestinal Microbiota And Diet in IBS: Causes, Consequences, or Epiphenomena?",
pages = "287-278",
number = "2",
volume = "110",
doi = "10.1038/ajg.2014.427"
}

Rajilić-Stojanović, M., Jonkers, D. M., Salonen, A., Hanevik, K., Raes, J., Jalanka, J., de Vos, W. M., Manichanh, C., Golić, N., Enck, P., Philippou, E., Iraqi, F. A., Clarke, G., Spiller, R. C.,& Penders, J.. (2015). Intestinal Microbiota And Diet in IBS: Causes, Consequences, or Epiphenomena?. in American Journal of Gastroenterology
Lippincott Williams & Wilkins, Philadelphia., 110(2), 278-287.
https://doi.org/10.1038/ajg.2014.427

Rajilić-Stojanović M, Jonkers DM, Salonen A, Hanevik K, Raes J, Jalanka J, de Vos WM, Manichanh C, Golić N, Enck P, Philippou E, Iraqi FA, Clarke G, Spiller RC, Penders J. Intestinal Microbiota And Diet in IBS: Causes, Consequences, or Epiphenomena?. in American Journal of Gastroenterology. 2015;110(2):278-287.
doi:10.1038/ajg.2014.427 .

Rajilić-Stojanović, Mirjana, Jonkers, Daisy M., Salonen, Anne, Hanevik, Kurt, Raes, Jeroen, Jalanka, Jonna, de Vos, Willem M., Manichanh, Chaysavanh, Golić, Nataša, Enck, Paul, Philippou, Elena, Iraqi, Fuad A., Clarke, Gerard, Spiller, Robin C., Penders, John, "Intestinal Microbiota And Diet in IBS: Causes, Consequences, or Epiphenomena?" in American Journal of Gastroenterology, 110, no. 2 (2015):278-287,
https://doi.org/10.1038/ajg.2014.427 . .