TY  - JOUR
AU  - Prlainović, Nevena Ž.
AU  - Milovanović, Jelena S.
AU  - Milašinović, Nikola Z.
AU  - Bezbradica, Dejan I.
AU  - Mijin, Dušan Ž.
PY  - 2024
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/7363
AB  - Lipase-catalyzed organic reactions have been widely practiced in the past three decades. Especially interesting are insoluble/immobilized forms due to providing a possibility of facile use and recyclability, thus reducing process costs, and making the procedure more environmentally friendly. Carbon-based supports have been extensively exploited for this purpose, because of neutral and biodegradable nature and thermal and chemical stability. Their high specific surface area, characteristic surface morphology and lower mass transfer resistances play a vital role in the performance of the attached enzyme. This review paper presents an overview of the main aspects of lipase immobilized on multi-walled carbon nanotubes (MWCNTs). Moreover, different immobilization strategies to achieve a biocatalyst with improved performances are discussed. Furthermore, as lipases are considered to have high commercial worth for synthesis of valuable organic molecules, the second part of the paper is dedicated to the overview of the most important industrial sectors in which these nanobiocatalysts have been used. In specific, applications in biodiesel production, flavour ester synthesis and racemization are summarized.
AB  - Lipaze su poslednjih decenija široko rasprostanjeni katalizatoriu raznovrsnim organskim reakcijama. Posebno su interesantne u imobilisanom/nerastvornom obliku jer je na ovaj način olakšana njihova upotreba uz mogućnost recikliranja i ponovne upotrebe čime se smanjuju troškovi samog procesa i postupak je ekološki prihvatljiviji. Kao nosači za vezivanje nanomaterijali na bazi ugljenika, posebno ugljenične nanocevi, su našli primenu zbog svojih izuzetnih fizičkih, mehaničkih i hemijskih svojstava. Njihova velika specifična površina, karakteristična površinska morfologija i smanjen otpor prenosu mase igraju vitalnu ulogu u performansama vezanog enzima. Ovaj pregledni rad predstavlja prikaz glavnih aspekata lipaze imobilisane na višeslojne ugljenične nanocevi i različitih strategija imobilizacije za dobijanje biokatalizatora sa poboljšanim svojstvima. Takođe, kako su lipaze enzimi od velikog komercijalnog značaja za organsku sintezu i primenu u biotehnologiji, drugi deo rada posvećen je pregledu najvažnijih industrijskih sektora u kojima su ovi nanobiokatalizatori našli primenu. Shodno tome, dat je pregled proizvodnje biodizela, mirisnih estara i racemizacije
PB  - Savez hemijskih inženjera Srbije
T2  - Hemijska industrija
T1  - Multi-walled carbon nanotubes as lipase carriers for organic synthesis: current trends and recent update
T1  - Višeslojne ugljenične nanocevi kao nosač lipaze za organsku sintezu: pregled najnovijih trendova
EP  - 16
IS  - 1
SP  - 1
VL  - 78
DO  - 10.2298/HEMIND230614003P
ER  - 

@article{
author = "Prlainović, Nevena Ž. and Milovanović, Jelena S. and Milašinović, Nikola Z. and Bezbradica, Dejan I. and Mijin, Dušan Ž.",
year = "2024",
abstract = "Lipase-catalyzed organic reactions have been widely practiced in the past three decades. Especially interesting are insoluble/immobilized forms due to providing a possibility of facile use and recyclability, thus reducing process costs, and making the procedure more environmentally friendly. Carbon-based supports have been extensively exploited for this purpose, because of neutral and biodegradable nature and thermal and chemical stability. Their high specific surface area, characteristic surface morphology and lower mass transfer resistances play a vital role in the performance of the attached enzyme. This review paper presents an overview of the main aspects of lipase immobilized on multi-walled carbon nanotubes (MWCNTs). Moreover, different immobilization strategies to achieve a biocatalyst with improved performances are discussed. Furthermore, as lipases are considered to have high commercial worth for synthesis of valuable organic molecules, the second part of the paper is dedicated to the overview of the most important industrial sectors in which these nanobiocatalysts have been used. In specific, applications in biodiesel production, flavour ester synthesis and racemization are summarized., Lipaze su poslednjih decenija široko rasprostanjeni katalizatoriu raznovrsnim organskim reakcijama. Posebno su interesantne u imobilisanom/nerastvornom obliku jer je na ovaj način olakšana njihova upotreba uz mogućnost recikliranja i ponovne upotrebe čime se smanjuju troškovi samog procesa i postupak je ekološki prihvatljiviji. Kao nosači za vezivanje nanomaterijali na bazi ugljenika, posebno ugljenične nanocevi, su našli primenu zbog svojih izuzetnih fizičkih, mehaničkih i hemijskih svojstava. Njihova velika specifična površina, karakteristična površinska morfologija i smanjen otpor prenosu mase igraju vitalnu ulogu u performansama vezanog enzima. Ovaj pregledni rad predstavlja prikaz glavnih aspekata lipaze imobilisane na višeslojne ugljenične nanocevi i različitih strategija imobilizacije za dobijanje biokatalizatora sa poboljšanim svojstvima. Takođe, kako su lipaze enzimi od velikog komercijalnog značaja za organsku sintezu i primenu u biotehnologiji, drugi deo rada posvećen je pregledu najvažnijih industrijskih sektora u kojima su ovi nanobiokatalizatori našli primenu. Shodno tome, dat je pregled proizvodnje biodizela, mirisnih estara i racemizacije",
publisher = "Savez hemijskih inženjera Srbije",
journal = "Hemijska industrija",
title = "Multi-walled carbon nanotubes as lipase carriers for organic synthesis: current trends and recent update, Višeslojne ugljenične nanocevi kao nosač lipaze za organsku sintezu: pregled najnovijih trendova",
pages = "16-1",
number = "1",
volume = "78",
doi = "10.2298/HEMIND230614003P"
}

Prlainović, N. Ž., Milovanović, J. S., Milašinović, N. Z., Bezbradica, D. I.,& Mijin, D. Ž.. (2024). Multi-walled carbon nanotubes as lipase carriers for organic synthesis: current trends and recent update. in Hemijska industrija
Savez hemijskih inženjera Srbije., 78(1), 1-16.
https://doi.org/10.2298/HEMIND230614003P

Prlainović NŽ, Milovanović JS, Milašinović NZ, Bezbradica DI, Mijin DŽ. Multi-walled carbon nanotubes as lipase carriers for organic synthesis: current trends and recent update. in Hemijska industrija. 2024;78(1):1-16.
doi:10.2298/HEMIND230614003P .

Prlainović, Nevena Ž., Milovanović, Jelena S., Milašinović, Nikola Z., Bezbradica, Dejan I., Mijin, Dušan Ž., "Multi-walled carbon nanotubes as lipase carriers for organic synthesis: current trends and recent update" in Hemijska industrija, 78, no. 1 (2024):1-16,
https://doi.org/10.2298/HEMIND230614003P . .

TY  - JOUR
AU  - Milovanović, Jelena
AU  - Luque, Rafael
AU  - Tschentscher, Roman
AU  - Romero, Antonio A.
AU  - Li, Hangkong
AU  - Shih, Kaimin
AU  - Rajić, Nevenka
PY  - 2017
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/5848
AB  - Several NiO contained-zeolites (NiO/H-ZSM-5, NiO/H-BETA and NiO/H-Y) prepared by a mechanochemical dry milling (MCDM) were tested in the pyrolysis of two hardwood lignins: Eucalyptus (EUC) and a mixture of birch and aspen woods (BA). All prepared catalysts increased the yield of aromatics and decreased the yield of oxygenates as compared to non-catalytic experiment. The catalytic activity depends on the lignin type and zeolite structural features. The highest liquid and gas yields and lowest coke yield was obtained with NiO/H-Y which also increased the amounts of desirable and decreased undesirable pyrolysis products, giving a high concentration of hydrogen in the gaseous phase. The highest yield of aromatics and the lowest yield of oxygenates was obtained with NiO/H-ZSM-5. The obtained results showed that BA is a more suitable feedstock, producing higher yields of liquids and aromatics and lower yields of coke and oxygenates.
PB  - Elsevier Ltd
T2  - Biomass and Bioenergy
T1  - Study on the pyrolysis products of two different hardwood lignins in the presence of NiO contained-zeolites
EP  - 34
SP  - 29
VL  - 103
DO  - 10.1016/j.biombioe.2017.05.007
ER  - 

@article{
author = "Milovanović, Jelena and Luque, Rafael and Tschentscher, Roman and Romero, Antonio A. and Li, Hangkong and Shih, Kaimin and Rajić, Nevenka",
year = "2017",
abstract = "Several NiO contained-zeolites (NiO/H-ZSM-5, NiO/H-BETA and NiO/H-Y) prepared by a mechanochemical dry milling (MCDM) were tested in the pyrolysis of two hardwood lignins: Eucalyptus (EUC) and a mixture of birch and aspen woods (BA). All prepared catalysts increased the yield of aromatics and decreased the yield of oxygenates as compared to non-catalytic experiment. The catalytic activity depends on the lignin type and zeolite structural features. The highest liquid and gas yields and lowest coke yield was obtained with NiO/H-Y which also increased the amounts of desirable and decreased undesirable pyrolysis products, giving a high concentration of hydrogen in the gaseous phase. The highest yield of aromatics and the lowest yield of oxygenates was obtained with NiO/H-ZSM-5. The obtained results showed that BA is a more suitable feedstock, producing higher yields of liquids and aromatics and lower yields of coke and oxygenates.",
publisher = "Elsevier Ltd",
journal = "Biomass and Bioenergy",
title = "Study on the pyrolysis products of two different hardwood lignins in the presence of NiO contained-zeolites",
pages = "34-29",
volume = "103",
doi = "10.1016/j.biombioe.2017.05.007"
}

Milovanović, J., Luque, R., Tschentscher, R., Romero, A. A., Li, H., Shih, K.,& Rajić, N.. (2017). Study on the pyrolysis products of two different hardwood lignins in the presence of NiO contained-zeolites. in Biomass and Bioenergy
Elsevier Ltd., 103, 29-34.
https://doi.org/10.1016/j.biombioe.2017.05.007

Milovanović J, Luque R, Tschentscher R, Romero AA, Li H, Shih K, Rajić N. Study on the pyrolysis products of two different hardwood lignins in the presence of NiO contained-zeolites. in Biomass and Bioenergy. 2017;103:29-34.
doi:10.1016/j.biombioe.2017.05.007 .

Milovanović, Jelena, Luque, Rafael, Tschentscher, Roman, Romero, Antonio A., Li, Hangkong, Shih, Kaimin, Rajić, Nevenka, "Study on the pyrolysis products of two different hardwood lignins in the presence of NiO contained-zeolites" in Biomass and Bioenergy, 103 (2017):29-34,
https://doi.org/10.1016/j.biombioe.2017.05.007 . .

TY  - JOUR
AU  - Milovanović, Jelena
AU  - Rajić, Nevenka
AU  - Romero, Antonio A.
AU  - Li, Hangkong
AU  - Shih, Kaimin
AU  - Tschentscher, Roman
AU  - Luque, Rafael
PY  - 2016
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3233
AB  - The depolymerization of biolignin (BL), eucalyptus (EL), and hardwood lignins (HL) to simple aromatics was studied by a microwave assisted approach using NiO/H-ZSM-S zeolites as catalysts. The catalysts prepared by the mechanochemical dry milling (MCDM) method contained bunsenite nano NiO particles with an average size of 67 mu m at a concentration of 1-4.8 wt % NiO. Yields and composition of the obtained bio-oils are highly dependent on lignin type as well as on the content of NiO. The highest bio-oil yield (about 20 wt %) was obtained using 3.5 wt % NiO and HL as the feedstock. A number of relevant findings based depolymerization experiments are provided which pointed to different monomeric products (mostly S-derived) that could be produced in different proportions depending on the source of investigated lignin and content of the NiO at H-ZSM-5.
PB  - Amer Chemical Soc, Washington
T2  - ACS Sustainable Chemistry & Engineering
T1  - Insights into the Microwave-Assisted Mild Deconstruction of Lignin Feedstocks Using NiO-Containing ZSM-5 Zeolites
EP  - 4313
IS  - 8
SP  - 4305
VL  - 4
DO  - 10.1021/acssuschemeng.6b00825
ER  - 

@article{
author = "Milovanović, Jelena and Rajić, Nevenka and Romero, Antonio A. and Li, Hangkong and Shih, Kaimin and Tschentscher, Roman and Luque, Rafael",
year = "2016",
abstract = "The depolymerization of biolignin (BL), eucalyptus (EL), and hardwood lignins (HL) to simple aromatics was studied by a microwave assisted approach using NiO/H-ZSM-S zeolites as catalysts. The catalysts prepared by the mechanochemical dry milling (MCDM) method contained bunsenite nano NiO particles with an average size of 67 mu m at a concentration of 1-4.8 wt % NiO. Yields and composition of the obtained bio-oils are highly dependent on lignin type as well as on the content of NiO. The highest bio-oil yield (about 20 wt %) was obtained using 3.5 wt % NiO and HL as the feedstock. A number of relevant findings based depolymerization experiments are provided which pointed to different monomeric products (mostly S-derived) that could be produced in different proportions depending on the source of investigated lignin and content of the NiO at H-ZSM-5.",
publisher = "Amer Chemical Soc, Washington",
journal = "ACS Sustainable Chemistry & Engineering",
title = "Insights into the Microwave-Assisted Mild Deconstruction of Lignin Feedstocks Using NiO-Containing ZSM-5 Zeolites",
pages = "4313-4305",
number = "8",
volume = "4",
doi = "10.1021/acssuschemeng.6b00825"
}

Milovanović, J., Rajić, N., Romero, A. A., Li, H., Shih, K., Tschentscher, R.,& Luque, R.. (2016). Insights into the Microwave-Assisted Mild Deconstruction of Lignin Feedstocks Using NiO-Containing ZSM-5 Zeolites. in ACS Sustainable Chemistry & Engineering
Amer Chemical Soc, Washington., 4(8), 4305-4313.
https://doi.org/10.1021/acssuschemeng.6b00825

Milovanović J, Rajić N, Romero AA, Li H, Shih K, Tschentscher R, Luque R. Insights into the Microwave-Assisted Mild Deconstruction of Lignin Feedstocks Using NiO-Containing ZSM-5 Zeolites. in ACS Sustainable Chemistry & Engineering. 2016;4(8):4305-4313.
doi:10.1021/acssuschemeng.6b00825 .

Milovanović, Jelena, Rajić, Nevenka, Romero, Antonio A., Li, Hangkong, Shih, Kaimin, Tschentscher, Roman, Luque, Rafael, "Insights into the Microwave-Assisted Mild Deconstruction of Lignin Feedstocks Using NiO-Containing ZSM-5 Zeolites" in ACS Sustainable Chemistry & Engineering, 4, no. 8 (2016):4305-4313,
https://doi.org/10.1021/acssuschemeng.6b00825 . .

TY  - CONF
AU  - Milovanović, Jelena
AU  - Rajić, Nevenka
AU  - Stensrød, R.E.
AU  - Tschentscher, R.
AU  - Stöcker, M
PY  - 2014
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/6404
AB  - A main objective of this work was to investigate and compare catalytic activity of the natural clinoptilolite (NZ) and ZSM-5 which are modified with several oxide species: NiO, Cu2O, MgO and CaO in the pyrolysis of softwood and hardwood lignin. The lignocellulose as cheapest and most abundant source of biomass has attracted considerable attention as very promising substitute for fossil fuels.
PB  - Universität Leipzig
C3  - 6th FEZA Conference 2014 Leipzig: “Porous Systems: From Novel Materials to Sustainable Solutions”
T1  - Lignin pyrolysis in the presence of oxide particles embedded onto natural clinoptilolite and ZSM-5
IS  - P2-109
UR  - https://hdl.handle.net/21.15107/rcub_technorep_6404
ER  - 

@conference{
author = "Milovanović, Jelena and Rajić, Nevenka and Stensrød, R.E. and Tschentscher, R. and Stöcker, M",
year = "2014",
abstract = "A main objective of this work was to investigate and compare catalytic activity of the natural clinoptilolite (NZ) and ZSM-5 which are modified with several oxide species: NiO, Cu2O, MgO and CaO in the pyrolysis of softwood and hardwood lignin. The lignocellulose as cheapest and most abundant source of biomass has attracted considerable attention as very promising substitute for fossil fuels.",
publisher = "Universität Leipzig",
journal = "6th FEZA Conference 2014 Leipzig: “Porous Systems: From Novel Materials to Sustainable Solutions”",
title = "Lignin pyrolysis in the presence of oxide particles embedded onto natural clinoptilolite and ZSM-5",
number = "P2-109",
url = "https://hdl.handle.net/21.15107/rcub_technorep_6404"
}

Milovanović, J., Rajić, N., Stensrød, R.E., Tschentscher, R.,& Stöcker, M.. (2014). Lignin pyrolysis in the presence of oxide particles embedded onto natural clinoptilolite and ZSM-5. in 6th FEZA Conference 2014 Leipzig: “Porous Systems: From Novel Materials to Sustainable Solutions”
Universität Leipzig.(P2-109).
https://hdl.handle.net/21.15107/rcub_technorep_6404

Milovanović J, Rajić N, Stensrød R, Tschentscher R, Stöcker M. Lignin pyrolysis in the presence of oxide particles embedded onto natural clinoptilolite and ZSM-5. in 6th FEZA Conference 2014 Leipzig: “Porous Systems: From Novel Materials to Sustainable Solutions”. 2014;(P2-109).
https://hdl.handle.net/21.15107/rcub_technorep_6404 .

Milovanović, Jelena, Rajić, Nevenka, Stensrød, R.E., Tschentscher, R., Stöcker, M, "Lignin pyrolysis in the presence of oxide particles embedded onto natural clinoptilolite and ZSM-5" in 6th FEZA Conference 2014 Leipzig: “Porous Systems: From Novel Materials to Sustainable Solutions”, no. P2-109 (2014),
https://hdl.handle.net/21.15107/rcub_technorep_6404 .