TY  - JOUR
AU  - Lukić, Jelena
AU  - Ražić, Slavica
AU  - Bakić, Tamara
AU  - Topić, Aleksandra
AU  - Onjia, Antonije
PY  - 2023
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/6060
AB  - A fast and straightforward reversed-phase dispersive liquid–liquid microextraction (RP-DLLME) using a deep eutectic solvent (DES) procedure to determine free tryptophan in vegetable oils was developed. The influence of eight variables affecting the RP-DLLME efficiency has been studied by a multivariate approach. A Plackett–Burman design for screening the most influential variables followed by a central composite response surface methodology led to an optimum RP-DLLME setup for a 1 g oil sample: 9 mL hexane as the diluting solvent, vortex extraction with 0.45 mL of DES (choline chloride–urea) at 40 ◦C, without addition of salt, and centrifugation at 6000 rpm for 4.0 min. The reconstituted extract was directly injected into a high-performance liquid chromatography (HPLC) system working in the diode array mode. At the studied concentration levels, the obtained method detection limits (MDL) was 11 mg/kg, linearity in matrix-matched standards was R2 ≥ 0.997, relative standard deviations (RSD) was 7.8%, and average recovery was 93%. The combined use of the recently developed DES -based RP-DLLME and HPLC provides an innovative, efficient, cost-effective, and more sustainable method for the extraction and quantification of free tryptophan in oily food matrices. The method was employed to analyze cold-pressed oils from nine vegetables (Brazil nut, almond, cashew, hazelnut, peanut, pumpkin, sesame, sunflower, and walnut) for the first time. The results showed that free tryptophan was present in the range of 11–38 mg/100 g. This article is important for its contributions to the field of food analysis, and for its development of a new and efficient method for the determination of free tryptophan in complex matrices, which has the potential to be applied to other analytes and sample types.
PB  - MDPI
T2  - Molecules
T1  - Deep Eutectic Solvent Based Reversed-Phase Dispersive Liquid–Liquid Microextraction and High-Performance Liquid Chromatography for the Determination of Free Tryptophan in Cold-Pressed Oils
IS  - 5
SP  - 2395
VL  - 28
DO  - 10.3390/molecules28052395
ER  - 

@article{
author = "Lukić, Jelena and Ražić, Slavica and Bakić, Tamara and Topić, Aleksandra and Onjia, Antonije",
year = "2023",
abstract = "A fast and straightforward reversed-phase dispersive liquid–liquid microextraction (RP-DLLME) using a deep eutectic solvent (DES) procedure to determine free tryptophan in vegetable oils was developed. The influence of eight variables affecting the RP-DLLME efficiency has been studied by a multivariate approach. A Plackett–Burman design for screening the most influential variables followed by a central composite response surface methodology led to an optimum RP-DLLME setup for a 1 g oil sample: 9 mL hexane as the diluting solvent, vortex extraction with 0.45 mL of DES (choline chloride–urea) at 40 ◦C, without addition of salt, and centrifugation at 6000 rpm for 4.0 min. The reconstituted extract was directly injected into a high-performance liquid chromatography (HPLC) system working in the diode array mode. At the studied concentration levels, the obtained method detection limits (MDL) was 11 mg/kg, linearity in matrix-matched standards was R2 ≥ 0.997, relative standard deviations (RSD) was 7.8%, and average recovery was 93%. The combined use of the recently developed DES -based RP-DLLME and HPLC provides an innovative, efficient, cost-effective, and more sustainable method for the extraction and quantification of free tryptophan in oily food matrices. The method was employed to analyze cold-pressed oils from nine vegetables (Brazil nut, almond, cashew, hazelnut, peanut, pumpkin, sesame, sunflower, and walnut) for the first time. The results showed that free tryptophan was present in the range of 11–38 mg/100 g. This article is important for its contributions to the field of food analysis, and for its development of a new and efficient method for the determination of free tryptophan in complex matrices, which has the potential to be applied to other analytes and sample types.",
publisher = "MDPI",
journal = "Molecules",
title = "Deep Eutectic Solvent Based Reversed-Phase Dispersive Liquid–Liquid Microextraction and High-Performance Liquid Chromatography for the Determination of Free Tryptophan in Cold-Pressed Oils",
number = "5",
pages = "2395",
volume = "28",
doi = "10.3390/molecules28052395"
}

Lukić, J., Ražić, S., Bakić, T., Topić, A.,& Onjia, A.. (2023). Deep Eutectic Solvent Based Reversed-Phase Dispersive Liquid–Liquid Microextraction and High-Performance Liquid Chromatography for the Determination of Free Tryptophan in Cold-Pressed Oils. in Molecules
MDPI., 28(5), 2395.
https://doi.org/10.3390/molecules28052395

Lukić J, Ražić S, Bakić T, Topić A, Onjia A. Deep Eutectic Solvent Based Reversed-Phase Dispersive Liquid–Liquid Microextraction and High-Performance Liquid Chromatography for the Determination of Free Tryptophan in Cold-Pressed Oils. in Molecules. 2023;28(5):2395.
doi:10.3390/molecules28052395 .

Lukić, Jelena, Ražić, Slavica, Bakić, Tamara, Topić, Aleksandra, Onjia, Antonije, "Deep Eutectic Solvent Based Reversed-Phase Dispersive Liquid–Liquid Microextraction and High-Performance Liquid Chromatography for the Determination of Free Tryptophan in Cold-Pressed Oils" in Molecules, 28, no. 5 (2023):2395,
https://doi.org/10.3390/molecules28052395 . .

TY  - JOUR
AU  - Đurđić, Slađana
AU  - Mišković-Stanković, Vesna
AU  - Ražić, Slavica
AU  - Mutić, Jelena
PY  - 2020
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4416
AB  - The analysis of isotope ratios of lead in the mushrooms and soil, where they were grown, assisted with a principal component analysis, offered a new perspective for understanding possible chemical environment in a real setup of those compartments. The content of lead and its isotope compositions were determined in soil samples and mushroom Macrolepiota procera from unpolluted area of Mountain Goč, Serbia. Sequential extraction procedure based on the Commission of the European Community Bureau of Reference (BCR) was applied on soil samples in order to determine the distribution of lead in the labile and un-labile fractions of the soil. Caps and stipes of mushrooms were subjected to microwave acid-assisted digestion prior to measurements by inductively coupled plasma quadrupole mass spectrometer for determination of lead content and lead isotope ratios. Information about the chemical fractionation of Pb in soil, Pb isotopic data from soil fractions and fruiting bodies allowed a more detailed insight on the uptake mechanisms. Lead was predominantly associated with reducible fraction (~ 60%). Only its small portion (∼ 1%) was present in the exchangeable and acid-extractable fractions suggesting the low mobility of Pb. Lead isotope analysis revealed the presence of anthropogenic lead in the surface soil. Significant lower 206Pb/207Pb compared with other fractions was found in exchangeable and acid-soluble fraction (1.331 ± 0.010), which corresponds to the isotope ratio of European gasoline. The highest 206Pb/207Pb ratio was observed in reducible fraction (1.162 ± 0.007), while in oxidizable and residual fraction, those values were similar (1.159 ± 0.006 and 1.159 ± 0.004, respectively). Distinction of exchangeable and acid-extractable fractions from others was also confirmed, for the first time, by principal component analysis. The analysis of four isotope ratios (206Pb/207Pb, 208Pb/206Pb, 206Pb/204Pb, and 207Pb/204Pb) indicated that the analyzed M. procera accumulates lead from the first two fractions of topsoil layers.
PB  - Springer Nature
T2  - Environmental Science and Pollution Research
T1  - Lead isotope ratios as tool for elucidation of chemical environment in a system of Macrolepiota procera (Scop.) Singer - soil
DO  - 10.1007/s11356-020-07947-6
ER  - 

@article{
author = "Đurđić, Slađana and Mišković-Stanković, Vesna and Ražić, Slavica and Mutić, Jelena",
year = "2020",
abstract = "The analysis of isotope ratios of lead in the mushrooms and soil, where they were grown, assisted with a principal component analysis, offered a new perspective for understanding possible chemical environment in a real setup of those compartments. The content of lead and its isotope compositions were determined in soil samples and mushroom Macrolepiota procera from unpolluted area of Mountain Goč, Serbia. Sequential extraction procedure based on the Commission of the European Community Bureau of Reference (BCR) was applied on soil samples in order to determine the distribution of lead in the labile and un-labile fractions of the soil. Caps and stipes of mushrooms were subjected to microwave acid-assisted digestion prior to measurements by inductively coupled plasma quadrupole mass spectrometer for determination of lead content and lead isotope ratios. Information about the chemical fractionation of Pb in soil, Pb isotopic data from soil fractions and fruiting bodies allowed a more detailed insight on the uptake mechanisms. Lead was predominantly associated with reducible fraction (~ 60%). Only its small portion (∼ 1%) was present in the exchangeable and acid-extractable fractions suggesting the low mobility of Pb. Lead isotope analysis revealed the presence of anthropogenic lead in the surface soil. Significant lower 206Pb/207Pb compared with other fractions was found in exchangeable and acid-soluble fraction (1.331 ± 0.010), which corresponds to the isotope ratio of European gasoline. The highest 206Pb/207Pb ratio was observed in reducible fraction (1.162 ± 0.007), while in oxidizable and residual fraction, those values were similar (1.159 ± 0.006 and 1.159 ± 0.004, respectively). Distinction of exchangeable and acid-extractable fractions from others was also confirmed, for the first time, by principal component analysis. The analysis of four isotope ratios (206Pb/207Pb, 208Pb/206Pb, 206Pb/204Pb, and 207Pb/204Pb) indicated that the analyzed M. procera accumulates lead from the first two fractions of topsoil layers.",
publisher = "Springer Nature",
journal = "Environmental Science and Pollution Research",
title = "Lead isotope ratios as tool for elucidation of chemical environment in a system of Macrolepiota procera (Scop.) Singer - soil",
doi = "10.1007/s11356-020-07947-6"
}

Đurđić, S., Mišković-Stanković, V., Ražić, S.,& Mutić, J.. (2020). Lead isotope ratios as tool for elucidation of chemical environment in a system of Macrolepiota procera (Scop.) Singer - soil. in Environmental Science and Pollution Research
Springer Nature..
https://doi.org/10.1007/s11356-020-07947-6

Đurđić S, Mišković-Stanković V, Ražić S, Mutić J. Lead isotope ratios as tool for elucidation of chemical environment in a system of Macrolepiota procera (Scop.) Singer - soil. in Environmental Science and Pollution Research. 2020;.
doi:10.1007/s11356-020-07947-6 .

Đurđić, Slađana, Mišković-Stanković, Vesna, Ražić, Slavica, Mutić, Jelena, "Lead isotope ratios as tool for elucidation of chemical environment in a system of Macrolepiota procera (Scop.) Singer - soil" in Environmental Science and Pollution Research (2020),
https://doi.org/10.1007/s11356-020-07947-6 . .

TY  - JOUR
AU  - Ražić, Slavica
AU  - Onjia, Antonije
PY  - 2010
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/1715
AB  - Chemical analysis in conjunction with multivariate data evaluation methods was used to study elemental profiles and geographical origin of wines from central Balkan countries (Serbia Montenegro and Macedonia) Nine elements (Na K Mg Ca Fe Mn Zn Cu and Pb) chosen as chemical descriptors were analyzed in 41 commercial wine samples Unsupervised pattern recognition methods principal component analysis (PCA) and factor analysis identified the main factors controlling the data variability while the application of hierarchical cluster analysis (HCA) highlighted a differentiation between sample groups belonging to different variable inputs Three PCs were shown to be the most significant together accounting for 70 8% of the total variance Supervised pattern recognition methods linear discriminant analysis (LDA) k nearest neighbor (kNN) soft independent modeling of class analogy (SIMCA) and artificial neural network (ANN) applied to the classification of wine samples demonstrated different recognition and prediction abilities The recognition rate for LDA was 97 6% and the percentage of classification obtained by kNN SIMCA and ANN was 100% However the LDA method produced the best prediction rate of 83 3% whereas kNN SIMCA and ANN gave much lower percentages of correctly classified samples at 72 2 61 1 and 55 6% respectively Trace elements seem to be suitable descriptors for wine samples studied by classification methods since their concentrations comprising both natural and other sources of influence are attributed to grapegrowing and winemaking sites Comparison of pattern recognition methods reveals the difference in their classification power
PB  - Amer Soc Enology Viticulture, Davis
T2  - American Journal of Enology and Viticulture
T1  - Trace Element Analysis and Pattern Recognition Techniques in Classification of Wine from Central Balkan Countries
EP  - 511
IS  - 4
SP  - 506
VL  - 61
DO  - 10.5344/ajev.2010.10002
ER  - 

@article{
author = "Ražić, Slavica and Onjia, Antonije",
year = "2010",
abstract = "Chemical analysis in conjunction with multivariate data evaluation methods was used to study elemental profiles and geographical origin of wines from central Balkan countries (Serbia Montenegro and Macedonia) Nine elements (Na K Mg Ca Fe Mn Zn Cu and Pb) chosen as chemical descriptors were analyzed in 41 commercial wine samples Unsupervised pattern recognition methods principal component analysis (PCA) and factor analysis identified the main factors controlling the data variability while the application of hierarchical cluster analysis (HCA) highlighted a differentiation between sample groups belonging to different variable inputs Three PCs were shown to be the most significant together accounting for 70 8% of the total variance Supervised pattern recognition methods linear discriminant analysis (LDA) k nearest neighbor (kNN) soft independent modeling of class analogy (SIMCA) and artificial neural network (ANN) applied to the classification of wine samples demonstrated different recognition and prediction abilities The recognition rate for LDA was 97 6% and the percentage of classification obtained by kNN SIMCA and ANN was 100% However the LDA method produced the best prediction rate of 83 3% whereas kNN SIMCA and ANN gave much lower percentages of correctly classified samples at 72 2 61 1 and 55 6% respectively Trace elements seem to be suitable descriptors for wine samples studied by classification methods since their concentrations comprising both natural and other sources of influence are attributed to grapegrowing and winemaking sites Comparison of pattern recognition methods reveals the difference in their classification power",
publisher = "Amer Soc Enology Viticulture, Davis",
journal = "American Journal of Enology and Viticulture",
title = "Trace Element Analysis and Pattern Recognition Techniques in Classification of Wine from Central Balkan Countries",
pages = "511-506",
number = "4",
volume = "61",
doi = "10.5344/ajev.2010.10002"
}

Ražić, S.,& Onjia, A.. (2010). Trace Element Analysis and Pattern Recognition Techniques in Classification of Wine from Central Balkan Countries. in American Journal of Enology and Viticulture
Amer Soc Enology Viticulture, Davis., 61(4), 506-511.
https://doi.org/10.5344/ajev.2010.10002

Ražić S, Onjia A. Trace Element Analysis and Pattern Recognition Techniques in Classification of Wine from Central Balkan Countries. in American Journal of Enology and Viticulture. 2010;61(4):506-511.
doi:10.5344/ajev.2010.10002 .

Ražić, Slavica, Onjia, Antonije, "Trace Element Analysis and Pattern Recognition Techniques in Classification of Wine from Central Balkan Countries" in American Journal of Enology and Viticulture, 61, no. 4 (2010):506-511,
https://doi.org/10.5344/ajev.2010.10002 . .

TY  - JOUR
AU  - Milosavljević, Milutin
AU  - Marinković, Aleksandar
AU  - Ceković, Boban
AU  - Ražić, Slavica
PY  - 2007
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/1192
AB  - The reaction kinetics of the synthesis of sodium ethyl xanthogeneacetate from potassium ethylxanthogenate and sodium chloroacetate in distilled water as the reaction medium at 25, 30, 35 and 40°C, were investigated. The obtained reaction mixture was a complex system which demanded the use of two methods for the kinetic measurements. The reaction was followed using the conductrometric and UV/Vis spectrophotometric method with equimolar initial concentrations of the reactants and under pseudo-first order conditions with respect to one of the reactants. The rate constants of the pseudo-first order and second order reactions were calculated from the data. On the basis of the reaction constants, the activation parameters were calculated and are discussed.
AB  - Ispitivana je kinetika reakcije sinteze natrijum-etil-ksantogen-acetata iz kalijum-etil-ksantogenata i natrijum-hloracetata u destilovanoj vodi kao reakcionom medijumu i temperaturama 25, 30, 35 i 40°C. Reakciona smeša je kompleksan sistem koji je zahtevao korišćenje dve metode za kinetička merenja. Reakcije su praćene korišćenjem spektrofotometrijske i konduktometrijske metode pri ekvimolarnim početnim koncentracijama reaktanata kao i pri uslovima reakcija pseudo-prvog reda u odnosu na jedan od reaktanata. Reakcione konstante pseudo-prvog reda i drugog reda izračunate su na osnovu kinetičkih podataka. Na osnovu reakcionih konstanti izračunati su i diskutovani takođe i aktivacioni parametri.
PB  - Serbian Chemical Society, Belgrade
T2  - Journal of the Serbian Chemical Society
T1  - Kinetic study of the reaction between sodium chloroacetate and potassium ethylxanthogenate
T1  - Kinetička ispitivanja reakcije između natrijum-hloracetata i kalijum-etil-ksantata
EP  - 100
IS  - 2
SP  - 89
VL  - 72
UR  - https://hdl.handle.net/21.15107/rcub_technorep_1192
ER  - 

@article{
author = "Milosavljević, Milutin and Marinković, Aleksandar and Ceković, Boban and Ražić, Slavica",
year = "2007",
abstract = "The reaction kinetics of the synthesis of sodium ethyl xanthogeneacetate from potassium ethylxanthogenate and sodium chloroacetate in distilled water as the reaction medium at 25, 30, 35 and 40°C, were investigated. The obtained reaction mixture was a complex system which demanded the use of two methods for the kinetic measurements. The reaction was followed using the conductrometric and UV/Vis spectrophotometric method with equimolar initial concentrations of the reactants and under pseudo-first order conditions with respect to one of the reactants. The rate constants of the pseudo-first order and second order reactions were calculated from the data. On the basis of the reaction constants, the activation parameters were calculated and are discussed., Ispitivana je kinetika reakcije sinteze natrijum-etil-ksantogen-acetata iz kalijum-etil-ksantogenata i natrijum-hloracetata u destilovanoj vodi kao reakcionom medijumu i temperaturama 25, 30, 35 i 40°C. Reakciona smeša je kompleksan sistem koji je zahtevao korišćenje dve metode za kinetička merenja. Reakcije su praćene korišćenjem spektrofotometrijske i konduktometrijske metode pri ekvimolarnim početnim koncentracijama reaktanata kao i pri uslovima reakcija pseudo-prvog reda u odnosu na jedan od reaktanata. Reakcione konstante pseudo-prvog reda i drugog reda izračunate su na osnovu kinetičkih podataka. Na osnovu reakcionih konstanti izračunati su i diskutovani takođe i aktivacioni parametri.",
publisher = "Serbian Chemical Society, Belgrade",
journal = "Journal of the Serbian Chemical Society",
title = "Kinetic study of the reaction between sodium chloroacetate and potassium ethylxanthogenate, Kinetička ispitivanja reakcije između natrijum-hloracetata i kalijum-etil-ksantata",
pages = "100-89",
number = "2",
volume = "72",
url = "https://hdl.handle.net/21.15107/rcub_technorep_1192"
}

Milosavljević, M., Marinković, A., Ceković, B.,& Ražić, S.. (2007). Kinetic study of the reaction between sodium chloroacetate and potassium ethylxanthogenate. in Journal of the Serbian Chemical Society
Serbian Chemical Society, Belgrade., 72(2), 89-100.
https://hdl.handle.net/21.15107/rcub_technorep_1192

Milosavljević M, Marinković A, Ceković B, Ražić S. Kinetic study of the reaction between sodium chloroacetate and potassium ethylxanthogenate. in Journal of the Serbian Chemical Society. 2007;72(2):89-100.
https://hdl.handle.net/21.15107/rcub_technorep_1192 .

Milosavljević, Milutin, Marinković, Aleksandar, Ceković, Boban, Ražić, Slavica, "Kinetic study of the reaction between sodium chloroacetate and potassium ethylxanthogenate" in Journal of the Serbian Chemical Society, 72, no. 2 (2007):89-100,
https://hdl.handle.net/21.15107/rcub_technorep_1192 .

TY  - JOUR
AU  - Ražić, Slavica
AU  - Onjia, Antonije
AU  - Dogo, S
AU  - Slavković, Latinka J.
AU  - Popović, Aleksandar R.
PY  - 2005
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/813
AB  - The concentrations of Cu, Zn, Mn, Fe, K, Ca, Mg, Al, Ba and B in 26 herbal drugs of special importance in phytopharmacywere studied. Flame atomic absorption and emission spectrometry (FAAS, FAES), as well as inductively coupled plasma atomic emission spectrometry (ICP-AES), were applied in this work. The whole procedure, from sample preparation, via dissolution, to measurements, was validated by using CRM (NIST 1573a-tomato leaves), and the obtained recovery values are in the range from 91 to 102%. Drug samples originated from medicinal plants cultivated in Serbia contained Cu (4.47-14.08 mg kg(-1)), Zn (8.4-54.5 mg kg(-1)), Mn (9-155 mg kg(-1)), Fe (47-546 mg kg(-1)), K (0.20-6.24%), Ca (0.18-1.84%), Mg (0.13-1.09%), Al (16-416 mg kg(-1)), Ba (11.70-84.83 mg kg(-1)) and B (5.1-118.7 mg kg(-1)). In order to get a better insight into the elemental patterns, a common chemometric approach to data evaluation was used. Four significant factors identified by principal component analysis (PCA) were attributed partly to the significant influential sources and high mobility of some elements thus referring to potential anthropogenic contamination as well.
PB  - Elsevier, Amsterdam
T2  - Talanta
T1  - Determination of metal content in some herbal drugs - Empirical and chemometric approach
EP  - 239
IS  - 1
SP  - 233
VL  - 67
DO  - 10.1016/j.talanta.2005.03.023
ER  - 

@article{
author = "Ražić, Slavica and Onjia, Antonije and Dogo, S and Slavković, Latinka J. and Popović, Aleksandar R.",
year = "2005",
abstract = "The concentrations of Cu, Zn, Mn, Fe, K, Ca, Mg, Al, Ba and B in 26 herbal drugs of special importance in phytopharmacywere studied. Flame atomic absorption and emission spectrometry (FAAS, FAES), as well as inductively coupled plasma atomic emission spectrometry (ICP-AES), were applied in this work. The whole procedure, from sample preparation, via dissolution, to measurements, was validated by using CRM (NIST 1573a-tomato leaves), and the obtained recovery values are in the range from 91 to 102%. Drug samples originated from medicinal plants cultivated in Serbia contained Cu (4.47-14.08 mg kg(-1)), Zn (8.4-54.5 mg kg(-1)), Mn (9-155 mg kg(-1)), Fe (47-546 mg kg(-1)), K (0.20-6.24%), Ca (0.18-1.84%), Mg (0.13-1.09%), Al (16-416 mg kg(-1)), Ba (11.70-84.83 mg kg(-1)) and B (5.1-118.7 mg kg(-1)). In order to get a better insight into the elemental patterns, a common chemometric approach to data evaluation was used. Four significant factors identified by principal component analysis (PCA) were attributed partly to the significant influential sources and high mobility of some elements thus referring to potential anthropogenic contamination as well.",
publisher = "Elsevier, Amsterdam",
journal = "Talanta",
title = "Determination of metal content in some herbal drugs - Empirical and chemometric approach",
pages = "239-233",
number = "1",
volume = "67",
doi = "10.1016/j.talanta.2005.03.023"
}

Ražić, S., Onjia, A., Dogo, S., Slavković, L. J.,& Popović, A. R.. (2005). Determination of metal content in some herbal drugs - Empirical and chemometric approach. in Talanta
Elsevier, Amsterdam., 67(1), 233-239.
https://doi.org/10.1016/j.talanta.2005.03.023

Ražić S, Onjia A, Dogo S, Slavković LJ, Popović AR. Determination of metal content in some herbal drugs - Empirical and chemometric approach. in Talanta. 2005;67(1):233-239.
doi:10.1016/j.talanta.2005.03.023 .

Ražić, Slavica, Onjia, Antonije, Dogo, S, Slavković, Latinka J., Popović, Aleksandar R., "Determination of metal content in some herbal drugs - Empirical and chemometric approach" in Talanta, 67, no. 1 (2005):233-239,
https://doi.org/10.1016/j.talanta.2005.03.023 . .

TY  - JOUR
AU  - Ražić, Slavica
AU  - Onjia, Antonije
AU  - Potkonjak, Branislav
PY  - 2003
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/509
AB  - Elemental composition of Echinacea purpurea (Asteracae), grown in Serbia under strongly controlled conditions, has been studied. To distinguish elemental patterns of different parts of the plant, the content of Zn, Fe, Cu, Mn, Ca, Mg, Sr, Ni, and Li in root versus upper plant parts were determined, by flame atomic absorption and flame atomic emission spectrometry. Analyses of the mentioned elements in soil and in an ethanolic extract of E. purpurea were made, too. The trace element data were evaluated by multivariate methods, i.e. principal component analysis and hierarchical cluster analysis. This revealed two groups of elements (I: Fe, Cu, Mn, Li; II: Ca, Mg, Zn, Ni), while trace element profiles of root. stem, leaves, and flowers of this plant differed significantly. However, no significant difference in the trace element patterns between the summer and the autumn harvest samples was found.
PB  - Elsevier, Amsterdam
T2  - Journal of Pharmaceutical and Biomedical Analysis
T1  - Trace elements analysis of Echinacea purpurea - herbal medicinal
EP  - 850
IS  - 4
SP  - 845
VL  - 33
DO  - 10.1016/S0731-7085(03)00338-8
ER  - 

@article{
author = "Ražić, Slavica and Onjia, Antonije and Potkonjak, Branislav",
year = "2003",
abstract = "Elemental composition of Echinacea purpurea (Asteracae), grown in Serbia under strongly controlled conditions, has been studied. To distinguish elemental patterns of different parts of the plant, the content of Zn, Fe, Cu, Mn, Ca, Mg, Sr, Ni, and Li in root versus upper plant parts were determined, by flame atomic absorption and flame atomic emission spectrometry. Analyses of the mentioned elements in soil and in an ethanolic extract of E. purpurea were made, too. The trace element data were evaluated by multivariate methods, i.e. principal component analysis and hierarchical cluster analysis. This revealed two groups of elements (I: Fe, Cu, Mn, Li; II: Ca, Mg, Zn, Ni), while trace element profiles of root. stem, leaves, and flowers of this plant differed significantly. However, no significant difference in the trace element patterns between the summer and the autumn harvest samples was found.",
publisher = "Elsevier, Amsterdam",
journal = "Journal of Pharmaceutical and Biomedical Analysis",
title = "Trace elements analysis of Echinacea purpurea - herbal medicinal",
pages = "850-845",
number = "4",
volume = "33",
doi = "10.1016/S0731-7085(03)00338-8"
}

Ražić, S., Onjia, A.,& Potkonjak, B.. (2003). Trace elements analysis of Echinacea purpurea - herbal medicinal. in Journal of Pharmaceutical and Biomedical Analysis
Elsevier, Amsterdam., 33(4), 845-850.
https://doi.org/10.1016/S0731-7085(03)00338-8

Ražić S, Onjia A, Potkonjak B. Trace elements analysis of Echinacea purpurea - herbal medicinal. in Journal of Pharmaceutical and Biomedical Analysis. 2003;33(4):845-850.
doi:10.1016/S0731-7085(03)00338-8 .

Ražić, Slavica, Onjia, Antonije, Potkonjak, Branislav, "Trace elements analysis of Echinacea purpurea - herbal medicinal" in Journal of Pharmaceutical and Biomedical Analysis, 33, no. 4 (2003):845-850,
https://doi.org/10.1016/S0731-7085(03)00338-8 . .