TY  - CONF
AU  - Nešović, Katarina
AU  - Janković, Ana
AU  - Surudžić, Rade
AU  - Vukašinović-Sekulić, Maja
AU  - Kojić, Vesna
AU  - Radetić, Tamara
AU  - Mišković-Stanković, Vesna
PY  - 2022
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/6761
AB  - Recent advances in biomaterials science are increasingly focused
on (re)search for next-generation soft tissue regeneration solutions.
Hydrogel-based materials are becoming a focal point to address
many tissue engineering requirements, possessing exceptional biocompatibility,
with tailorable shape, structure and mechanical
properties, as well as infinite possibilities drug delivery. The widespread
antibiotics use has led to aggravated resistance issues in many
bacterial strains, so the focus is increasingly shifted towards alternative
antibacterial solutions such as silver nanoparticles (AgNPs).
In this work, we have developed novel composite materials based on
poly(vinyl alcohol)/chitosan (PVA/CHI) and poly(vinyl alcohol)/
chitosan/graphene (PVA/CHI/Gr) hydrogels with silver nanoparticles
obtained through green in situ constant-voltage electrochemical
synthesis. The obtained AgNPs’ properties, sizes and size
distributions were examined using UV-visible spectroscopy, dynamic
light scattering and transmission electron microscopy. In vitro
swelling and silver release kinetics were monitored in the simulated
physiological conditions (pH7.4, 37  C). The obtained release and
swelling isotherms were fitted with several theoretical models that
helped discern the mechanisms of these processes. Tensile testing
was carried out to examine the composites’ mechanical behavior and
elasticity – important properties for soft tissue engineering materials.
Finally, the excellent antibacterial activity of the obtained silver/
poly(vinyl alcohol)/chitosan (Ag/PVA/CHI) and silver/poly(vinyl
alcohol)/chitosan/graphene (Ag/PVA/CHI/Gr) hydrogels against
Staphylococcus aureus and Escherichia coli was confirmed quantitatively
by colony counting method, and their non-toxicity was
verified towards two model fibroblast cell lines (MRC-5 and L929)
utilizing the MTT assay. Through thorough characterization, the
obtained nanocomposite hydrogel materials were identified as strong
candidates for active antibacterial soft tissue engineering materials.
PB  - Mary Ann Liebert, Inc.
C3  - Tissue Engineering Part A
T1  - Silver Nanoparticles-Loaded Poly(Vinyl Alcohol)/Chitosan/Graphene Hydrogels Obtained by Electrochemical Synthesis
IS  - S1
SP  - S-132
VL  - 28
DO  - 10.1089/ten.tea.2022.29025.abstracts
ER  - 

@conference{
author = "Nešović, Katarina and Janković, Ana and Surudžić, Rade and Vukašinović-Sekulić, Maja and Kojić, Vesna and Radetić, Tamara and Mišković-Stanković, Vesna",
year = "2022",
abstract = "Recent advances in biomaterials science are increasingly focused
on (re)search for next-generation soft tissue regeneration solutions.
Hydrogel-based materials are becoming a focal point to address
many tissue engineering requirements, possessing exceptional biocompatibility,
with tailorable shape, structure and mechanical
properties, as well as infinite possibilities drug delivery. The widespread
antibiotics use has led to aggravated resistance issues in many
bacterial strains, so the focus is increasingly shifted towards alternative
antibacterial solutions such as silver nanoparticles (AgNPs).
In this work, we have developed novel composite materials based on
poly(vinyl alcohol)/chitosan (PVA/CHI) and poly(vinyl alcohol)/
chitosan/graphene (PVA/CHI/Gr) hydrogels with silver nanoparticles
obtained through green in situ constant-voltage electrochemical
synthesis. The obtained AgNPs’ properties, sizes and size
distributions were examined using UV-visible spectroscopy, dynamic
light scattering and transmission electron microscopy. In vitro
swelling and silver release kinetics were monitored in the simulated
physiological conditions (pH7.4, 37  C). The obtained release and
swelling isotherms were fitted with several theoretical models that
helped discern the mechanisms of these processes. Tensile testing
was carried out to examine the composites’ mechanical behavior and
elasticity – important properties for soft tissue engineering materials.
Finally, the excellent antibacterial activity of the obtained silver/
poly(vinyl alcohol)/chitosan (Ag/PVA/CHI) and silver/poly(vinyl
alcohol)/chitosan/graphene (Ag/PVA/CHI/Gr) hydrogels against
Staphylococcus aureus and Escherichia coli was confirmed quantitatively
by colony counting method, and their non-toxicity was
verified towards two model fibroblast cell lines (MRC-5 and L929)
utilizing the MTT assay. Through thorough characterization, the
obtained nanocomposite hydrogel materials were identified as strong
candidates for active antibacterial soft tissue engineering materials.",
publisher = "Mary Ann Liebert, Inc.",
journal = "Tissue Engineering Part A",
title = "Silver Nanoparticles-Loaded Poly(Vinyl Alcohol)/Chitosan/Graphene Hydrogels Obtained by Electrochemical Synthesis",
number = "S1",
pages = "S-132",
volume = "28",
doi = "10.1089/ten.tea.2022.29025.abstracts"
}

Nešović, K., Janković, A., Surudžić, R., Vukašinović-Sekulić, M., Kojić, V., Radetić, T.,& Mišković-Stanković, V.. (2022). Silver Nanoparticles-Loaded Poly(Vinyl Alcohol)/Chitosan/Graphene Hydrogels Obtained by Electrochemical Synthesis. in Tissue Engineering Part A
Mary Ann Liebert, Inc.., 28(S1), S-132.
https://doi.org/10.1089/ten.tea.2022.29025.abstracts

Nešović K, Janković A, Surudžić R, Vukašinović-Sekulić M, Kojić V, Radetić T, Mišković-Stanković V. Silver Nanoparticles-Loaded Poly(Vinyl Alcohol)/Chitosan/Graphene Hydrogels Obtained by Electrochemical Synthesis. in Tissue Engineering Part A. 2022;28(S1):S-132.
doi:10.1089/ten.tea.2022.29025.abstracts .

Nešović, Katarina, Janković, Ana, Surudžić, Rade, Vukašinović-Sekulić, Maja, Kojić, Vesna, Radetić, Tamara, Mišković-Stanković, Vesna, "Silver Nanoparticles-Loaded Poly(Vinyl Alcohol)/Chitosan/Graphene Hydrogels Obtained by Electrochemical Synthesis" in Tissue Engineering Part A, 28, no. S1 (2022):S-132,
https://doi.org/10.1089/ten.tea.2022.29025.abstracts . .

TY  - JOUR
AU  - Nešović, Katarina
AU  - Mišković-Stanković, Vesna
PY  - 2022
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4985
AB  - Long-term wound healing and chronic wound care represent significant challenges for biomaterials science and engineering with many diverse requirements for the wound dressing properties, as well as antibacterial efficacy and antibacterial agent release to prevent and treat persistent infections. Silver nanoparticles, as a wide-spectrum antibacterial agent that does not induce bacterial resistance, are very convenient for use as an active component in antibacterial hydrogel wound dressing materials with the controlled release ability. In this work, we aim to perform a comprehensive analysis of silver release from poly(vinyl alcohol)-based hydrogels with electrochemically synthesized antibacterial silver nanoparticles (AgNPs), aimed for wound dressing applications. Different AgNPs concentrations were loaded in hydrogel matrices using the green electrochemical reduction method, and thus synthesized nanocomposite hydrogels were characterized by different techniques (scanning electron microscopy, Fourier-transform infrared and Raman spectroscopy, and differential scanning calorimetry), in order to assess their physico-chemical and thermal properties. Silver release was monitored for 28 days in physiologically-relevant conditions (phosphate buffered medium, pH 7.4, 37 degrees C). The obtained experimental data were evaluated against several theoretical release models (Korsmeyer-Peppas, Higuchi, Makoid-Banakar, Kopcha, and early-time approximation), which confirmed the predominantly diffusion-controlled mechanism of release. Finally, AgNP-loaded hydrogels were assessed for antibacterial activity against Staphylococcus aureus TL and Escherichia coli ATCC25922 bacterial strains, to prove their strong potential for wound dressing applications.
T2  - Journal of Vinyl & Additive Technology
T1  - Silver/poly(vinyl alcohol)/graphene hydrogels for wound dressing applications: Understanding the mechanism of silver, antibacterial agent release
EP  - 210
IS  - 1
SP  - 196
VL  - 28
DO  - 10.1002/vnl.21882
ER  - 

@article{
author = "Nešović, Katarina and Mišković-Stanković, Vesna",
year = "2022",
abstract = "Long-term wound healing and chronic wound care represent significant challenges for biomaterials science and engineering with many diverse requirements for the wound dressing properties, as well as antibacterial efficacy and antibacterial agent release to prevent and treat persistent infections. Silver nanoparticles, as a wide-spectrum antibacterial agent that does not induce bacterial resistance, are very convenient for use as an active component in antibacterial hydrogel wound dressing materials with the controlled release ability. In this work, we aim to perform a comprehensive analysis of silver release from poly(vinyl alcohol)-based hydrogels with electrochemically synthesized antibacterial silver nanoparticles (AgNPs), aimed for wound dressing applications. Different AgNPs concentrations were loaded in hydrogel matrices using the green electrochemical reduction method, and thus synthesized nanocomposite hydrogels were characterized by different techniques (scanning electron microscopy, Fourier-transform infrared and Raman spectroscopy, and differential scanning calorimetry), in order to assess their physico-chemical and thermal properties. Silver release was monitored for 28 days in physiologically-relevant conditions (phosphate buffered medium, pH 7.4, 37 degrees C). The obtained experimental data were evaluated against several theoretical release models (Korsmeyer-Peppas, Higuchi, Makoid-Banakar, Kopcha, and early-time approximation), which confirmed the predominantly diffusion-controlled mechanism of release. Finally, AgNP-loaded hydrogels were assessed for antibacterial activity against Staphylococcus aureus TL and Escherichia coli ATCC25922 bacterial strains, to prove their strong potential for wound dressing applications.",
journal = "Journal of Vinyl & Additive Technology",
title = "Silver/poly(vinyl alcohol)/graphene hydrogels for wound dressing applications: Understanding the mechanism of silver, antibacterial agent release",
pages = "210-196",
number = "1",
volume = "28",
doi = "10.1002/vnl.21882"
}

Nešović, K.,& Mišković-Stanković, V.. (2022). Silver/poly(vinyl alcohol)/graphene hydrogels for wound dressing applications: Understanding the mechanism of silver, antibacterial agent release. in Journal of Vinyl & Additive Technology, 28(1), 196-210.
https://doi.org/10.1002/vnl.21882

Nešović K, Mišković-Stanković V. Silver/poly(vinyl alcohol)/graphene hydrogels for wound dressing applications: Understanding the mechanism of silver, antibacterial agent release. in Journal of Vinyl & Additive Technology. 2022;28(1):196-210.
doi:10.1002/vnl.21882 .

Nešović, Katarina, Mišković-Stanković, Vesna, "Silver/poly(vinyl alcohol)/graphene hydrogels for wound dressing applications: Understanding the mechanism of silver, antibacterial agent release" in Journal of Vinyl & Additive Technology, 28, no. 1 (2022):196-210,
https://doi.org/10.1002/vnl.21882 . .

TY  - JOUR
AU  - Lužajić-Božinovski, Tijana
AU  - Todorovic, Vera
AU  - Milosevic, Ivan
AU  - Prokić, Bogomir Bolka
AU  - Gajdov, Vladimir
AU  - Nešović, Katarina
AU  - Mišković-Stanković, Vesna
AU  - Markovic, Danica
PY  - 2022
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/5021
AB  - Biocompatibility of materials is one of the most important conditions for their successful application in tissue regeneration and repair. Cell-surface interactions stimulate adhesion and activation of macrophages whose acquaintance can assist in designing novel biomaterials that promote favorable macrophage-biomaterial surface interactions for clinical application. This study is designed to determine the distribution and number of macrophages as a means of biocompatibility evaluation of two newly synthesized materials [silver/poly(vinyl alcohol) (Ag/PVA) and silver/poly(vinyl alcohol)/graphene (Ag/PVA/Gr) nanocomposite hydrogels] in vivo, with approval of the Ethics Committee of the Faculty of Veterinary Medicine, University of Belgrade. Macrophages and giant cells were analyzed in tissue sections stained by routine H&E and immunohistochemical methods (CD68(+)). Statistical relevance was determined in the statistical software package SPSS 20 (IBM corp). The results of the study in terms of the number of giant cells localized around the implant showed that their number was highest on the seventh postoperative day (p.o.d.) in the group implanted with Ag/PVA hydrogels, and on the 30th p.o.d. in the group implanted with Ag/PVA/Gr. Interestingly, the number of macrophages measured in the capsular and pericapsular space was highest in the group implanted with the commercial Suprasorb
T2  - Journal of Biomaterials Applications
T1  - Macrophages, the main marker in biocompatibility evaluation of new hydrogels after subcutaneous implantation in rats
EP  - 1125
IS  - 6
SP  - 1111
VL  - 36
DO  - 10.1177/08853282211046119
ER  - 

@article{
author = "Lužajić-Božinovski, Tijana and Todorovic, Vera and Milosevic, Ivan and Prokić, Bogomir Bolka and Gajdov, Vladimir and Nešović, Katarina and Mišković-Stanković, Vesna and Markovic, Danica",
year = "2022",
abstract = "Biocompatibility of materials is one of the most important conditions for their successful application in tissue regeneration and repair. Cell-surface interactions stimulate adhesion and activation of macrophages whose acquaintance can assist in designing novel biomaterials that promote favorable macrophage-biomaterial surface interactions for clinical application. This study is designed to determine the distribution and number of macrophages as a means of biocompatibility evaluation of two newly synthesized materials [silver/poly(vinyl alcohol) (Ag/PVA) and silver/poly(vinyl alcohol)/graphene (Ag/PVA/Gr) nanocomposite hydrogels] in vivo, with approval of the Ethics Committee of the Faculty of Veterinary Medicine, University of Belgrade. Macrophages and giant cells were analyzed in tissue sections stained by routine H&E and immunohistochemical methods (CD68(+)). Statistical relevance was determined in the statistical software package SPSS 20 (IBM corp). The results of the study in terms of the number of giant cells localized around the implant showed that their number was highest on the seventh postoperative day (p.o.d.) in the group implanted with Ag/PVA hydrogels, and on the 30th p.o.d. in the group implanted with Ag/PVA/Gr. Interestingly, the number of macrophages measured in the capsular and pericapsular space was highest in the group implanted with the commercial Suprasorb",
journal = "Journal of Biomaterials Applications",
title = "Macrophages, the main marker in biocompatibility evaluation of new hydrogels after subcutaneous implantation in rats",
pages = "1125-1111",
number = "6",
volume = "36",
doi = "10.1177/08853282211046119"
}

Lužajić-Božinovski, T., Todorovic, V., Milosevic, I., Prokić, B. B., Gajdov, V., Nešović, K., Mišković-Stanković, V.,& Markovic, D.. (2022). Macrophages, the main marker in biocompatibility evaluation of new hydrogels after subcutaneous implantation in rats. in Journal of Biomaterials Applications, 36(6), 1111-1125.
https://doi.org/10.1177/08853282211046119

Lužajić-Božinovski T, Todorovic V, Milosevic I, Prokić BB, Gajdov V, Nešović K, Mišković-Stanković V, Markovic D. Macrophages, the main marker in biocompatibility evaluation of new hydrogels after subcutaneous implantation in rats. in Journal of Biomaterials Applications. 2022;36(6):1111-1125.
doi:10.1177/08853282211046119 .

Lužajić-Božinovski, Tijana, Todorovic, Vera, Milosevic, Ivan, Prokić, Bogomir Bolka, Gajdov, Vladimir, Nešović, Katarina, Mišković-Stanković, Vesna, Markovic, Danica, "Macrophages, the main marker in biocompatibility evaluation of new hydrogels after subcutaneous implantation in rats" in Journal of Biomaterials Applications, 36, no. 6 (2022):1111-1125,
https://doi.org/10.1177/08853282211046119 . .

TY  - JOUR
AU  - Lužajić-Božinovski, Tijana
AU  - Todorovic, Vera
AU  - Milosevic, Ivan
AU  - Gajdov, Vladimir
AU  - Prokić, Bogomir Bolka
AU  - Nešović, Katarina
AU  - Mišković-Stanković, Vesna
AU  - Markovic, Danica
PY  - 2021
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4812
AB  - A newly produced biomaterial is necessarily subject of standards, which are performed in vivo on animal models. For the evaluation of soft tissue regenerative possibilities after subcutaneous implantation of biomaterials - silver/poly(vinyl alcohol) (Ag/PVA) and novel silver/poly(vinyl alcohol)/graphene (Ag/PVA/Gr) provided for clinical use, sixteen rats were used, according to the instructions of international standards, ISO 10993-6, 2007. Histological sections were observed 7, 15, 30 and 60 days after grafting. These hydrogels were produced by in situ electrochemical synthesis of silver nanoparticles in the polymer matrices, which enabled obtaining completely safe and biocompatible materials, free from any additional toxic chemical reducing agents. Surgical implantation of hydrogels was done according to the permission of the Ethical Committee of the Faculty of Veterinary Medicine, University of Belgrade. Immunohistochemical (IHC) studies included the assessment of smooth muscle expression actin in blood vessels (alpha-SMA), the expression of laminin and type I and type III collagen in the skin structures, and, the determination of cell proliferation marker expression (Ki-67) keratinocytes. The results were assessed in a semiquantitative manner. The data were analyzed in the statistical software package IBM SPSS 20. The conclusions indicated that Ag/PVA/Gr might be used as wound dressings to enhance the tissue healing potential and established faster integration and shorter retention in the tissue.
T2  - Acta Veterinaria-Beograd
T1  - Evaluation of soft tissue regenerative processes after subcutaneous implantation of silver/ poly(vinyl alcohol) and novel silver/poly(vinyl alcohol)/graphene hydrogels in an animal model
EP  - 302
IS  - 3
SP  - 285
VL  - 71
DO  - 10.2478/acve-2021-0025
ER  - 

@article{
author = "Lužajić-Božinovski, Tijana and Todorovic, Vera and Milosevic, Ivan and Gajdov, Vladimir and Prokić, Bogomir Bolka and Nešović, Katarina and Mišković-Stanković, Vesna and Markovic, Danica",
year = "2021",
abstract = "A newly produced biomaterial is necessarily subject of standards, which are performed in vivo on animal models. For the evaluation of soft tissue regenerative possibilities after subcutaneous implantation of biomaterials - silver/poly(vinyl alcohol) (Ag/PVA) and novel silver/poly(vinyl alcohol)/graphene (Ag/PVA/Gr) provided for clinical use, sixteen rats were used, according to the instructions of international standards, ISO 10993-6, 2007. Histological sections were observed 7, 15, 30 and 60 days after grafting. These hydrogels were produced by in situ electrochemical synthesis of silver nanoparticles in the polymer matrices, which enabled obtaining completely safe and biocompatible materials, free from any additional toxic chemical reducing agents. Surgical implantation of hydrogels was done according to the permission of the Ethical Committee of the Faculty of Veterinary Medicine, University of Belgrade. Immunohistochemical (IHC) studies included the assessment of smooth muscle expression actin in blood vessels (alpha-SMA), the expression of laminin and type I and type III collagen in the skin structures, and, the determination of cell proliferation marker expression (Ki-67) keratinocytes. The results were assessed in a semiquantitative manner. The data were analyzed in the statistical software package IBM SPSS 20. The conclusions indicated that Ag/PVA/Gr might be used as wound dressings to enhance the tissue healing potential and established faster integration and shorter retention in the tissue.",
journal = "Acta Veterinaria-Beograd",
title = "Evaluation of soft tissue regenerative processes after subcutaneous implantation of silver/ poly(vinyl alcohol) and novel silver/poly(vinyl alcohol)/graphene hydrogels in an animal model",
pages = "302-285",
number = "3",
volume = "71",
doi = "10.2478/acve-2021-0025"
}

Lužajić-Božinovski, T., Todorovic, V., Milosevic, I., Gajdov, V., Prokić, B. B., Nešović, K., Mišković-Stanković, V.,& Markovic, D.. (2021). Evaluation of soft tissue regenerative processes after subcutaneous implantation of silver/ poly(vinyl alcohol) and novel silver/poly(vinyl alcohol)/graphene hydrogels in an animal model. in Acta Veterinaria-Beograd, 71(3), 285-302.
https://doi.org/10.2478/acve-2021-0025

Lužajić-Božinovski T, Todorovic V, Milosevic I, Gajdov V, Prokić BB, Nešović K, Mišković-Stanković V, Markovic D. Evaluation of soft tissue regenerative processes after subcutaneous implantation of silver/ poly(vinyl alcohol) and novel silver/poly(vinyl alcohol)/graphene hydrogels in an animal model. in Acta Veterinaria-Beograd. 2021;71(3):285-302.
doi:10.2478/acve-2021-0025 .

Lužajić-Božinovski, Tijana, Todorovic, Vera, Milosevic, Ivan, Gajdov, Vladimir, Prokić, Bogomir Bolka, Nešović, Katarina, Mišković-Stanković, Vesna, Markovic, Danica, "Evaluation of soft tissue regenerative processes after subcutaneous implantation of silver/ poly(vinyl alcohol) and novel silver/poly(vinyl alcohol)/graphene hydrogels in an animal model" in Acta Veterinaria-Beograd, 71, no. 3 (2021):285-302,
https://doi.org/10.2478/acve-2021-0025 . .

TY  - JOUR
AU  - Nešović, Katarina
AU  - Janković, Ana
AU  - Radetić, Tamara
AU  - Perić-Grujić, Aleksandra
AU  - Vukašinović-Sekulić, Maja
AU  - Kojić, Vesna
AU  - Rhee, Kyong Yop
AU  - Mišković-Stanković, Vesna
PY  - 2020
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4495
AB  - Polymer-based hydrogel materials are excellent candidates for new-generation wound dressings with improved properties, such as high sorption ability, good mechanical properties and low adhesiveness. Cross-linked hydrogel matrices also serve as excellent carriers for controlled release of antibacterial agents, such as silver nanoparticles (AgNPs), which are preferred over conventional antibiotics due to low propensity to induce bacterial resistance. In this work, we aim to produce novel silver/poly(vinyl alcohol)/chitosan (Ag/PVA/CHI) hydrogels for wound dressing applications. The electrochemical AgNPs synthesis provided facile and green method for the reduction of Ag+ ions inside the hydrogel matrices, without the need to use toxic chemical reducing agents. The formation of AgNPs was confirmed using UV-visible spectroscopy, scanning and transmission electron microscopy. Release kinetics was investigated in modified phosphate buffer solution at 37 degrees C to mimic physiological conditions. Release profiles indicated "burst release" behavior, which is beneficial for wound dressing applications. The antibacterial activity was evaluated against Staphylococcus aureus and Escherichia coli strains using disc-diffusion test, and non-toxicity of hydrogels was proved by dye-exclusion test. The obtained results confirmed strong potential of Ag/PVA/CHI hydrogels for biomedical applications.
PB  - Int Assoc Physical Chemists-Iapc, Zagreb
T2  - Journal of Electrochemical Science and Engineering
T1  - Poly(vinyl alcohol)/chitosan hydrogels with electrochemically synthesized silver nanoparticles for wound dressing applications
EP  - 198
IS  - 2
SP  - 185
VL  - 10
DO  - 10.5599/jese.732
ER  - 

@article{
author = "Nešović, Katarina and Janković, Ana and Radetić, Tamara and Perić-Grujić, Aleksandra and Vukašinović-Sekulić, Maja and Kojić, Vesna and Rhee, Kyong Yop and Mišković-Stanković, Vesna",
year = "2020",
abstract = "Polymer-based hydrogel materials are excellent candidates for new-generation wound dressings with improved properties, such as high sorption ability, good mechanical properties and low adhesiveness. Cross-linked hydrogel matrices also serve as excellent carriers for controlled release of antibacterial agents, such as silver nanoparticles (AgNPs), which are preferred over conventional antibiotics due to low propensity to induce bacterial resistance. In this work, we aim to produce novel silver/poly(vinyl alcohol)/chitosan (Ag/PVA/CHI) hydrogels for wound dressing applications. The electrochemical AgNPs synthesis provided facile and green method for the reduction of Ag+ ions inside the hydrogel matrices, without the need to use toxic chemical reducing agents. The formation of AgNPs was confirmed using UV-visible spectroscopy, scanning and transmission electron microscopy. Release kinetics was investigated in modified phosphate buffer solution at 37 degrees C to mimic physiological conditions. Release profiles indicated "burst release" behavior, which is beneficial for wound dressing applications. The antibacterial activity was evaluated against Staphylococcus aureus and Escherichia coli strains using disc-diffusion test, and non-toxicity of hydrogels was proved by dye-exclusion test. The obtained results confirmed strong potential of Ag/PVA/CHI hydrogels for biomedical applications.",
publisher = "Int Assoc Physical Chemists-Iapc, Zagreb",
journal = "Journal of Electrochemical Science and Engineering",
title = "Poly(vinyl alcohol)/chitosan hydrogels with electrochemically synthesized silver nanoparticles for wound dressing applications",
pages = "198-185",
number = "2",
volume = "10",
doi = "10.5599/jese.732"
}

Nešović, K., Janković, A., Radetić, T., Perić-Grujić, A., Vukašinović-Sekulić, M., Kojić, V., Rhee, K. Y.,& Mišković-Stanković, V.. (2020). Poly(vinyl alcohol)/chitosan hydrogels with electrochemically synthesized silver nanoparticles for wound dressing applications. in Journal of Electrochemical Science and Engineering
Int Assoc Physical Chemists-Iapc, Zagreb., 10(2), 185-198.
https://doi.org/10.5599/jese.732

Nešović K, Janković A, Radetić T, Perić-Grujić A, Vukašinović-Sekulić M, Kojić V, Rhee KY, Mišković-Stanković V. Poly(vinyl alcohol)/chitosan hydrogels with electrochemically synthesized silver nanoparticles for wound dressing applications. in Journal of Electrochemical Science and Engineering. 2020;10(2):185-198.
doi:10.5599/jese.732 .

Nešović, Katarina, Janković, Ana, Radetić, Tamara, Perić-Grujić, Aleksandra, Vukašinović-Sekulić, Maja, Kojić, Vesna, Rhee, Kyong Yop, Mišković-Stanković, Vesna, "Poly(vinyl alcohol)/chitosan hydrogels with electrochemically synthesized silver nanoparticles for wound dressing applications" in Journal of Electrochemical Science and Engineering, 10, no. 2 (2020):185-198,
https://doi.org/10.5599/jese.732 . .

TY  - JOUR
AU  - Stevanović, Milena
AU  - Đošić, Marija
AU  - Janković, Ana
AU  - Nešović, Katarina
AU  - Kojić, Vesna
AU  - Stojanović, Jovica
AU  - Grujić, Svetlana
AU  - Matić-Bujagić, Ivana
AU  - Rhee, Kyong Yop
AU  - Mišković-Stanković, Vesna
PY  - 2020
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4498
AB  - The electrophoretic deposition process (EPD) was utilized to produce bioactive hydroxyapatite/chitosan (HAP/CS) and hydroxyapatite/chitosan/gentamicin (HAP/CS/Gent) coatings on titanium. The bioactivity of newly synthesized composite coatings was investigated in the simulated body fluid (SBF) and examined by X-ray diffraction, Fourier transform infrared spectroscopy, and field emission scanning electron microscopy. The obtained results revealed carbonate-substituted hydroxyapatite after immersion in SBF, emphasizing the similarity of the biomimetically grown HAP with the naturally occurring apatite in the bone. The formation of biomimetic HAP was confirmed by electrochemical impedance spectroscopy and polarization measurements, through the decrease in corrosion current density and coating capacitance values after 28-day immersion in SBF. The osseointegration ability was further validated by measuring the alkaline phosphatase activity (ALP) indicating the favorable osseopromotive properties of deposited coatings (significant increase in ALP levels for both HAP/CS (3.206 U mL(-1)) and HAP/CS/Gent (4.039 U mL(-1)) coatings, compared to the control (0.900 U mL(-1))). Drug-release kinetics was investigated in deionized water at 37 degrees C by high-performance liquid chromatography coupled with mass spectrometry. Release profiles revealed the beneficial "burst-release effect" (similar to 21% of gentamicin released in the first 48 h) as a potentially promising solution against the biofilm formation in the initial period. When tested against human and mice fibroblast cells (MRC-5 and L929), both composite coatings showed a noncytotoxic effect (viability  gt 85%), providing a promising basis for further medical application trials.
PB  - Amer Chemical Soc, Washington
T2  - ACS Omega
T1  - Assessing the Bioactivity of Gentamicin-Preloaded Hydroxyapatite/Chitosan Composite Coating on Titanium Substrate
EP  - 15445
IS  - 25
SP  - 15433
VL  - 5
DO  - 10.1021/acsomega.0c01583
ER  - 

@article{
author = "Stevanović, Milena and Đošić, Marija and Janković, Ana and Nešović, Katarina and Kojić, Vesna and Stojanović, Jovica and Grujić, Svetlana and Matić-Bujagić, Ivana and Rhee, Kyong Yop and Mišković-Stanković, Vesna",
year = "2020",
abstract = "The electrophoretic deposition process (EPD) was utilized to produce bioactive hydroxyapatite/chitosan (HAP/CS) and hydroxyapatite/chitosan/gentamicin (HAP/CS/Gent) coatings on titanium. The bioactivity of newly synthesized composite coatings was investigated in the simulated body fluid (SBF) and examined by X-ray diffraction, Fourier transform infrared spectroscopy, and field emission scanning electron microscopy. The obtained results revealed carbonate-substituted hydroxyapatite after immersion in SBF, emphasizing the similarity of the biomimetically grown HAP with the naturally occurring apatite in the bone. The formation of biomimetic HAP was confirmed by electrochemical impedance spectroscopy and polarization measurements, through the decrease in corrosion current density and coating capacitance values after 28-day immersion in SBF. The osseointegration ability was further validated by measuring the alkaline phosphatase activity (ALP) indicating the favorable osseopromotive properties of deposited coatings (significant increase in ALP levels for both HAP/CS (3.206 U mL(-1)) and HAP/CS/Gent (4.039 U mL(-1)) coatings, compared to the control (0.900 U mL(-1))). Drug-release kinetics was investigated in deionized water at 37 degrees C by high-performance liquid chromatography coupled with mass spectrometry. Release profiles revealed the beneficial "burst-release effect" (similar to 21% of gentamicin released in the first 48 h) as a potentially promising solution against the biofilm formation in the initial period. When tested against human and mice fibroblast cells (MRC-5 and L929), both composite coatings showed a noncytotoxic effect (viability  gt 85%), providing a promising basis for further medical application trials.",
publisher = "Amer Chemical Soc, Washington",
journal = "ACS Omega",
title = "Assessing the Bioactivity of Gentamicin-Preloaded Hydroxyapatite/Chitosan Composite Coating on Titanium Substrate",
pages = "15445-15433",
number = "25",
volume = "5",
doi = "10.1021/acsomega.0c01583"
}

Stevanović, M., Đošić, M., Janković, A., Nešović, K., Kojić, V., Stojanović, J., Grujić, S., Matić-Bujagić, I., Rhee, K. Y.,& Mišković-Stanković, V.. (2020). Assessing the Bioactivity of Gentamicin-Preloaded Hydroxyapatite/Chitosan Composite Coating on Titanium Substrate. in ACS Omega
Amer Chemical Soc, Washington., 5(25), 15433-15445.
https://doi.org/10.1021/acsomega.0c01583

Stevanović M, Đošić M, Janković A, Nešović K, Kojić V, Stojanović J, Grujić S, Matić-Bujagić I, Rhee KY, Mišković-Stanković V. Assessing the Bioactivity of Gentamicin-Preloaded Hydroxyapatite/Chitosan Composite Coating on Titanium Substrate. in ACS Omega. 2020;5(25):15433-15445.
doi:10.1021/acsomega.0c01583 .

Stevanović, Milena, Đošić, Marija, Janković, Ana, Nešović, Katarina, Kojić, Vesna, Stojanović, Jovica, Grujić, Svetlana, Matić-Bujagić, Ivana, Rhee, Kyong Yop, Mišković-Stanković, Vesna, "Assessing the Bioactivity of Gentamicin-Preloaded Hydroxyapatite/Chitosan Composite Coating on Titanium Substrate" in ACS Omega, 5, no. 25 (2020):15433-15445,
https://doi.org/10.1021/acsomega.0c01583 . .

TY  - JOUR
AU  - Naghdi, Samira
AU  - Nešović, Katarina
AU  - Sanchez-Arriaga, Gonzalo
AU  - Song, Hyun Yong
AU  - Kim, Sung Wng
AU  - Rhee, Kyong Yop
AU  - Mišković-Stanković, Vesna
PY  - 2020
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4376
AB  - This study reports in-situ cesium-doped graphene (G/Cs) coating obtained by introducing Cs2CO3 into the atmospheric pressure chemical vapor deposition (APCVD) furnace during graphene deposition on copper. The successful Cs-doping of the graphene coating was confirmed via X-ray photoelectron spectroscopy (XPS). As compared to the spectra of pure graphene coating, the XPS spectra of the G/Cs coating revealed a shift of the C1s and Cs3d(5/2) peaks to higher and lower binding energies, respectively; thus, implying the n-type character of the doping and indicating a charge transfer between Cs and graphene. Raman results show that a pure graphene coating is composed of fewer layers, fewer defects, and larger domain size than the G/Cs coating. Ultraviolet photoelectron spectroscopy was utilized to study the work function of graphene and the G/Cs and revealed that doping graphene with Cs dopants reduced the work function of graphene by 1.2 eV. Electrochemical testing during 15-day immersion in 0.1 M NaCl indicated the destructive effect of the G/Cs coating on the Cu substrate. The results showed that the G/Cs coating exhibits a higher corrosion rate and lower corrosion resistance than even the bare metal itself.
PB  - Elsevier, Amsterdam
T2  - Journal of Materials Research and Technology-JMR&T
T1  - The effect of cesium dopant on APCVD graphene coating on copper
EP  - 9812
IS  - 5
SP  - 9798
VL  - 9
DO  - 10.1016/j.jmrt.2020.06.091
ER  - 

@article{
author = "Naghdi, Samira and Nešović, Katarina and Sanchez-Arriaga, Gonzalo and Song, Hyun Yong and Kim, Sung Wng and Rhee, Kyong Yop and Mišković-Stanković, Vesna",
year = "2020",
abstract = "This study reports in-situ cesium-doped graphene (G/Cs) coating obtained by introducing Cs2CO3 into the atmospheric pressure chemical vapor deposition (APCVD) furnace during graphene deposition on copper. The successful Cs-doping of the graphene coating was confirmed via X-ray photoelectron spectroscopy (XPS). As compared to the spectra of pure graphene coating, the XPS spectra of the G/Cs coating revealed a shift of the C1s and Cs3d(5/2) peaks to higher and lower binding energies, respectively; thus, implying the n-type character of the doping and indicating a charge transfer between Cs and graphene. Raman results show that a pure graphene coating is composed of fewer layers, fewer defects, and larger domain size than the G/Cs coating. Ultraviolet photoelectron spectroscopy was utilized to study the work function of graphene and the G/Cs and revealed that doping graphene with Cs dopants reduced the work function of graphene by 1.2 eV. Electrochemical testing during 15-day immersion in 0.1 M NaCl indicated the destructive effect of the G/Cs coating on the Cu substrate. The results showed that the G/Cs coating exhibits a higher corrosion rate and lower corrosion resistance than even the bare metal itself.",
publisher = "Elsevier, Amsterdam",
journal = "Journal of Materials Research and Technology-JMR&T",
title = "The effect of cesium dopant on APCVD graphene coating on copper",
pages = "9812-9798",
number = "5",
volume = "9",
doi = "10.1016/j.jmrt.2020.06.091"
}

Naghdi, S., Nešović, K., Sanchez-Arriaga, G., Song, H. Y., Kim, S. W., Rhee, K. Y.,& Mišković-Stanković, V.. (2020). The effect of cesium dopant on APCVD graphene coating on copper. in Journal of Materials Research and Technology-JMR&T
Elsevier, Amsterdam., 9(5), 9798-9812.
https://doi.org/10.1016/j.jmrt.2020.06.091

Naghdi S, Nešović K, Sanchez-Arriaga G, Song HY, Kim SW, Rhee KY, Mišković-Stanković V. The effect of cesium dopant on APCVD graphene coating on copper. in Journal of Materials Research and Technology-JMR&T. 2020;9(5):9798-9812.
doi:10.1016/j.jmrt.2020.06.091 .

Naghdi, Samira, Nešović, Katarina, Sanchez-Arriaga, Gonzalo, Song, Hyun Yong, Kim, Sung Wng, Rhee, Kyong Yop, Mišković-Stanković, Vesna, "The effect of cesium dopant on APCVD graphene coating on copper" in Journal of Materials Research and Technology-JMR&T, 9, no. 5 (2020):9798-9812,
https://doi.org/10.1016/j.jmrt.2020.06.091 . .

TY  - JOUR
AU  - Nešović, Katarina
AU  - Mišković-Stanković, Vesna
PY  - 2020
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4505
AB  - Modernization and improvement of wound dressing materials is an important topic in biomaterials and biomedicine fields, as the traditional materials are inadequate and susceptible to bacterial infections. In recent times, polymer-based hydrogel materials have presented themselves as excellent candidates for new-generation wound dressings with improved properties, such as high sorption ability, good mechanical properties, and low adhesiveness. Additionally, cross linked hydrogel matrices serve as excellent carriers for controlled release of antibacterial agents, such as silver nanoparticles (AgNPs), which are preferred over conventional antibiotics due to multi-phase mechanism of action and low susceptibility to induce bacterial resistance. Their incorporation inside polymer matrices allows improvement of wound dressing properties and sustained protection against bacterial infection. Electrochemical methods for AgNPs synthesis are facile and green alternatives to chemical routes, allowing the formation of highly stable AgNPs with strong antibacterial effect. In this article, we aim to provide a comprehensive review of the existing research on the topic of electrochemically synthesized silver nanoparticles incorporated in polymer matrices with a special focus on the chitosan-based hydrogels as prospective materials for wound dressing applications.
PB  - Wiley, Hoboken
T2  - Polymer Engineering and Science
T1  - A comprehensive review of the polymer-based hydrogels with electrochemically synthesized silver nanoparticles for wound dressing applications
EP  - 1419
IS  - 7
SP  - 1393
VL  - 60
DO  - 10.1002/pen.25410
ER  - 

@article{
author = "Nešović, Katarina and Mišković-Stanković, Vesna",
year = "2020",
abstract = "Modernization and improvement of wound dressing materials is an important topic in biomaterials and biomedicine fields, as the traditional materials are inadequate and susceptible to bacterial infections. In recent times, polymer-based hydrogel materials have presented themselves as excellent candidates for new-generation wound dressings with improved properties, such as high sorption ability, good mechanical properties, and low adhesiveness. Additionally, cross linked hydrogel matrices serve as excellent carriers for controlled release of antibacterial agents, such as silver nanoparticles (AgNPs), which are preferred over conventional antibiotics due to multi-phase mechanism of action and low susceptibility to induce bacterial resistance. Their incorporation inside polymer matrices allows improvement of wound dressing properties and sustained protection against bacterial infection. Electrochemical methods for AgNPs synthesis are facile and green alternatives to chemical routes, allowing the formation of highly stable AgNPs with strong antibacterial effect. In this article, we aim to provide a comprehensive review of the existing research on the topic of electrochemically synthesized silver nanoparticles incorporated in polymer matrices with a special focus on the chitosan-based hydrogels as prospective materials for wound dressing applications.",
publisher = "Wiley, Hoboken",
journal = "Polymer Engineering and Science",
title = "A comprehensive review of the polymer-based hydrogels with electrochemically synthesized silver nanoparticles for wound dressing applications",
pages = "1419-1393",
number = "7",
volume = "60",
doi = "10.1002/pen.25410"
}

Nešović, K.,& Mišković-Stanković, V.. (2020). A comprehensive review of the polymer-based hydrogels with electrochemically synthesized silver nanoparticles for wound dressing applications. in Polymer Engineering and Science
Wiley, Hoboken., 60(7), 1393-1419.
https://doi.org/10.1002/pen.25410

Nešović K, Mišković-Stanković V. A comprehensive review of the polymer-based hydrogels with electrochemically synthesized silver nanoparticles for wound dressing applications. in Polymer Engineering and Science. 2020;60(7):1393-1419.
doi:10.1002/pen.25410 .

Nešović, Katarina, Mišković-Stanković, Vesna, "A comprehensive review of the polymer-based hydrogels with electrochemically synthesized silver nanoparticles for wound dressing applications" in Polymer Engineering and Science, 60, no. 7 (2020):1393-1419,
https://doi.org/10.1002/pen.25410 . .

TY  - JOUR
AU  - Nešović, Katarina
AU  - Mišković-Stanković, Vesna
PY  - 2020
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4568
AB  - Silver nanoparticles (AgNPs) have become an interesting alternative to antibiotics for potential applications in biomedicine, since nanocrystalline silver is proved to be highly efficient antimicrobial agent with a wide inhibiting spectrum against many types of microorganisms. AgNPs embedded in hydrogel matrices are attractive for biomedical applications due to the possibility for their controlled release resulting in enhanced antimicrobial activity. Thus, combination of AgNPs with biocompatible hydrogels, poly(vinyl alcohol) (PVA) and chitosan (CHI), provides potential for design of improved medical treatments and devices (antimicrobial wound dressings, soft tissue implants). Graphene (Gr) has exceptional mechanical properties and has therefore been applied as adequate reinforcing component for polymer-based composite materials. The synthesis of AgNPs is always subject to innovation and improvements, as it is desirable to minimize the use of chemical agents with the aim of improving the biocompatibility of the obtained material. With this in mind, a green alternative to traditional chemical synthesis methods would be the electrochemical reduction of silver ions, especially as this method provides the option of direct in situ synthesis of AgNPs inside the polymer matrix. In this paper, we provide an overview of the state of the art regarding graphene-reinforced polymer matrices with electrochemically synthesized silver nanoparticles for medical application. We show that the electrochemical method of AgNPs synthesis in PVA/CHI hydrogel matrices has emerged as an excellent method to obtain nanoparticles, and that the incorporation of graphene improved the hydrogels` mechanical properties and elasticity.
T2  - Bulgarian Chemical Communications
T1  - Graphene-based poly(vinyl alcohol)/chitosan hydrogels with electrochemically synthesized silver nanoparticles for medical applications – A review
EP  - 14
SP  - 5
VL  - 52
UR  - https://hdl.handle.net/21.15107/rcub_technorep_4568
ER  - 

@article{
author = "Nešović, Katarina and Mišković-Stanković, Vesna",
year = "2020",
abstract = "Silver nanoparticles (AgNPs) have become an interesting alternative to antibiotics for potential applications in biomedicine, since nanocrystalline silver is proved to be highly efficient antimicrobial agent with a wide inhibiting spectrum against many types of microorganisms. AgNPs embedded in hydrogel matrices are attractive for biomedical applications due to the possibility for their controlled release resulting in enhanced antimicrobial activity. Thus, combination of AgNPs with biocompatible hydrogels, poly(vinyl alcohol) (PVA) and chitosan (CHI), provides potential for design of improved medical treatments and devices (antimicrobial wound dressings, soft tissue implants). Graphene (Gr) has exceptional mechanical properties and has therefore been applied as adequate reinforcing component for polymer-based composite materials. The synthesis of AgNPs is always subject to innovation and improvements, as it is desirable to minimize the use of chemical agents with the aim of improving the biocompatibility of the obtained material. With this in mind, a green alternative to traditional chemical synthesis methods would be the electrochemical reduction of silver ions, especially as this method provides the option of direct in situ synthesis of AgNPs inside the polymer matrix. In this paper, we provide an overview of the state of the art regarding graphene-reinforced polymer matrices with electrochemically synthesized silver nanoparticles for medical application. We show that the electrochemical method of AgNPs synthesis in PVA/CHI hydrogel matrices has emerged as an excellent method to obtain nanoparticles, and that the incorporation of graphene improved the hydrogels` mechanical properties and elasticity.",
journal = "Bulgarian Chemical Communications",
title = "Graphene-based poly(vinyl alcohol)/chitosan hydrogels with electrochemically synthesized silver nanoparticles for medical applications – A review",
pages = "14-5",
volume = "52",
url = "https://hdl.handle.net/21.15107/rcub_technorep_4568"
}

Nešović, K.,& Mišković-Stanković, V.. (2020). Graphene-based poly(vinyl alcohol)/chitosan hydrogels with electrochemically synthesized silver nanoparticles for medical applications – A review. in Bulgarian Chemical Communications, 52, 5-14.
https://hdl.handle.net/21.15107/rcub_technorep_4568

Nešović K, Mišković-Stanković V. Graphene-based poly(vinyl alcohol)/chitosan hydrogels with electrochemically synthesized silver nanoparticles for medical applications – A review. in Bulgarian Chemical Communications. 2020;52:5-14.
https://hdl.handle.net/21.15107/rcub_technorep_4568 .

Nešović, Katarina, Mišković-Stanković, Vesna, "Graphene-based poly(vinyl alcohol)/chitosan hydrogels with electrochemically synthesized silver nanoparticles for medical applications – A review" in Bulgarian Chemical Communications, 52 (2020):5-14,
https://hdl.handle.net/21.15107/rcub_technorep_4568 .

TY  - JOUR
AU  - Nešović, Katarina
AU  - Janković, Ana
AU  - Perić-Grujić, Aleksandra
AU  - Vukašinović-Sekulić, Maja
AU  - Radetić, Tamara
AU  - Živković, Ljiljana
AU  - Park, Soo Jin
AU  - Rhee, Kyong Yop
AU  - Mišković-Stanković, Vesna
PY  - 2019
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4239
AB  - Silver nanoparticles (AgNPs) were synthesized by in situ electrochemical reduction of Ag+ ions in poly (vinyl alcohol)/chitosan/graphene (PVA/CHI/Gr) hydrogel matrices with different concentrations of chitosan. The physicochemical properties of nanocomposite hydrogels were investigated by UV-vis spectroscopy (UV-vis), dynamic light scattering (DLS), transmission electron microscopy (TEM), X-ray photoelectron spectroscopy (XPS), field-emission scanning electron microscopy (FE-SEM) and Fourier transform infrared spectroscopy (FT-IR), thermal characteristics were determined by differential scanning calorimetry (DSC) and mechanical properties were measured by tensile test. The swelling studies were carried out in phosphate buffer to simulate natural physiological environment and data were fitted by several kinetic models to determine the diffusion mechanism and diffusion coefficients of the swelling medium through the hydrogel matrices. It was shown that the presence of silver nanoparticles increased the uptake capability and equilibrium swelling degree of the composite hydrogels. The antibacterial activity was confirmed against Escherichia coli and Staphylococcus aureus, while the hydrogels without AgNPs exhibited antibacterial properties due to the presence of chitosan. With the addition of AgNPs, the samples showed stronger activity and fast reduction in the number of colonies, confirming the synergistic effect of chitosan and AgNPs on the antibacterial activity.
PB  - Elsevier Science Inc, New York
T2  - Journal of Industrial and Engineering Chemistry
T1  - Kinetic models of swelling and thermal stability of silver/poly(vinyl Check far alcohol)/chitosan/graphene hydrogels
EP  - 96
SP  - 83
VL  - 77
DO  - 10.1016/j.jiec.2019.04.022
ER  - 

@article{
author = "Nešović, Katarina and Janković, Ana and Perić-Grujić, Aleksandra and Vukašinović-Sekulić, Maja and Radetić, Tamara and Živković, Ljiljana and Park, Soo Jin and Rhee, Kyong Yop and Mišković-Stanković, Vesna",
year = "2019",
abstract = "Silver nanoparticles (AgNPs) were synthesized by in situ electrochemical reduction of Ag+ ions in poly (vinyl alcohol)/chitosan/graphene (PVA/CHI/Gr) hydrogel matrices with different concentrations of chitosan. The physicochemical properties of nanocomposite hydrogels were investigated by UV-vis spectroscopy (UV-vis), dynamic light scattering (DLS), transmission electron microscopy (TEM), X-ray photoelectron spectroscopy (XPS), field-emission scanning electron microscopy (FE-SEM) and Fourier transform infrared spectroscopy (FT-IR), thermal characteristics were determined by differential scanning calorimetry (DSC) and mechanical properties were measured by tensile test. The swelling studies were carried out in phosphate buffer to simulate natural physiological environment and data were fitted by several kinetic models to determine the diffusion mechanism and diffusion coefficients of the swelling medium through the hydrogel matrices. It was shown that the presence of silver nanoparticles increased the uptake capability and equilibrium swelling degree of the composite hydrogels. The antibacterial activity was confirmed against Escherichia coli and Staphylococcus aureus, while the hydrogels without AgNPs exhibited antibacterial properties due to the presence of chitosan. With the addition of AgNPs, the samples showed stronger activity and fast reduction in the number of colonies, confirming the synergistic effect of chitosan and AgNPs on the antibacterial activity.",
publisher = "Elsevier Science Inc, New York",
journal = "Journal of Industrial and Engineering Chemistry",
title = "Kinetic models of swelling and thermal stability of silver/poly(vinyl Check far alcohol)/chitosan/graphene hydrogels",
pages = "96-83",
volume = "77",
doi = "10.1016/j.jiec.2019.04.022"
}

Nešović, K., Janković, A., Perić-Grujić, A., Vukašinović-Sekulić, M., Radetić, T., Živković, L., Park, S. J., Rhee, K. Y.,& Mišković-Stanković, V.. (2019). Kinetic models of swelling and thermal stability of silver/poly(vinyl Check far alcohol)/chitosan/graphene hydrogels. in Journal of Industrial and Engineering Chemistry
Elsevier Science Inc, New York., 77, 83-96.
https://doi.org/10.1016/j.jiec.2019.04.022

Nešović K, Janković A, Perić-Grujić A, Vukašinović-Sekulić M, Radetić T, Živković L, Park SJ, Rhee KY, Mišković-Stanković V. Kinetic models of swelling and thermal stability of silver/poly(vinyl Check far alcohol)/chitosan/graphene hydrogels. in Journal of Industrial and Engineering Chemistry. 2019;77:83-96.
doi:10.1016/j.jiec.2019.04.022 .

Nešović, Katarina, Janković, Ana, Perić-Grujić, Aleksandra, Vukašinović-Sekulić, Maja, Radetić, Tamara, Živković, Ljiljana, Park, Soo Jin, Rhee, Kyong Yop, Mišković-Stanković, Vesna, "Kinetic models of swelling and thermal stability of silver/poly(vinyl Check far alcohol)/chitosan/graphene hydrogels" in Journal of Industrial and Engineering Chemistry, 77 (2019):83-96,
https://doi.org/10.1016/j.jiec.2019.04.022 . .

TY  - JOUR
AU  - Nešović, Katarina
AU  - Janković, Ana
AU  - Perić-Grujić, Aleksandra
AU  - Vukašinović-Sekulić, Maja
AU  - Radetić, Tamara
AU  - Živković, Ljiljana
AU  - Park, Soo Jin
AU  - Rhee, Kyong Yop
AU  - Mišković-Stanković, Vesna
PY  - 2019
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/5044
AB  - Silver nanoparticles (AgNPs) were synthesized by in situ electrochemical reduction of Ag+ ions in poly(vinyl alcohol)/chitosan/graphene (PVA/CHI/Gr) hydrogel matrices with different concentrations of chitosan. The physicochemical properties of nanocomposite hydrogels were investigated by UV–vis spectroscopy (UV–vis), dynamic light scattering (DLS), transmission electron microscopy (TEM), X-ray photoelectron spectroscopy (XPS), field-emission scanning electron microscopy (FE-SEM) and Fourier-transform infrared spectroscopy (FT-IR), thermal characteristics were determined by differential scanning calorimetry (DSC) and mechanical properties were measured by tensile test. The swelling studies were carried out in phosphate buffer to simulate natural physiological environment and data were fitted by several kinetic models to determine the diffusion mechanism and diffusion coefficients of the swelling medium through the hydrogel matrices. It was shown that the presence of silver nanoparticles increased the uptake capability and equilibrium swelling degree of the composite hydrogels. The antibacterial activity was confirmed against Escherichia coli and Staphylococcus aureus, while the hydrogels without AgNPs exhibited antibacterial properties due to the presence of chitosan. With the addition of AgNPs, the samples showed stronger activity and fast reduction in the number of colonies, confirming the synergistic effect of chitosan and AgNPs on the antibacterial activity.
PB  - Korean Society of Industrial Engineering Chemistry
T2  - Journal of Industrial and Engineering Chemistry
T1  - Kinetic models of swelling and thermal stability of silver/poly(vinyl alcohol)/chitosan/graphene hydrogels
EP  - 96
SP  - 83
VL  - 77
DO  - 10.1016/j.jiec.2019.04.022
ER  - 

@article{
author = "Nešović, Katarina and Janković, Ana and Perić-Grujić, Aleksandra and Vukašinović-Sekulić, Maja and Radetić, Tamara and Živković, Ljiljana and Park, Soo Jin and Rhee, Kyong Yop and Mišković-Stanković, Vesna",
year = "2019",
abstract = "Silver nanoparticles (AgNPs) were synthesized by in situ electrochemical reduction of Ag+ ions in poly(vinyl alcohol)/chitosan/graphene (PVA/CHI/Gr) hydrogel matrices with different concentrations of chitosan. The physicochemical properties of nanocomposite hydrogels were investigated by UV–vis spectroscopy (UV–vis), dynamic light scattering (DLS), transmission electron microscopy (TEM), X-ray photoelectron spectroscopy (XPS), field-emission scanning electron microscopy (FE-SEM) and Fourier-transform infrared spectroscopy (FT-IR), thermal characteristics were determined by differential scanning calorimetry (DSC) and mechanical properties were measured by tensile test. The swelling studies were carried out in phosphate buffer to simulate natural physiological environment and data were fitted by several kinetic models to determine the diffusion mechanism and diffusion coefficients of the swelling medium through the hydrogel matrices. It was shown that the presence of silver nanoparticles increased the uptake capability and equilibrium swelling degree of the composite hydrogels. The antibacterial activity was confirmed against Escherichia coli and Staphylococcus aureus, while the hydrogels without AgNPs exhibited antibacterial properties due to the presence of chitosan. With the addition of AgNPs, the samples showed stronger activity and fast reduction in the number of colonies, confirming the synergistic effect of chitosan and AgNPs on the antibacterial activity.",
publisher = "Korean Society of Industrial Engineering Chemistry",
journal = "Journal of Industrial and Engineering Chemistry",
title = "Kinetic models of swelling and thermal stability of silver/poly(vinyl alcohol)/chitosan/graphene hydrogels",
pages = "96-83",
volume = "77",
doi = "10.1016/j.jiec.2019.04.022"
}

Nešović, K., Janković, A., Perić-Grujić, A., Vukašinović-Sekulić, M., Radetić, T., Živković, L., Park, S. J., Rhee, K. Y.,& Mišković-Stanković, V.. (2019). Kinetic models of swelling and thermal stability of silver/poly(vinyl alcohol)/chitosan/graphene hydrogels. in Journal of Industrial and Engineering Chemistry
Korean Society of Industrial Engineering Chemistry., 77, 83-96.
https://doi.org/10.1016/j.jiec.2019.04.022

Nešović K, Janković A, Perić-Grujić A, Vukašinović-Sekulić M, Radetić T, Živković L, Park SJ, Rhee KY, Mišković-Stanković V. Kinetic models of swelling and thermal stability of silver/poly(vinyl alcohol)/chitosan/graphene hydrogels. in Journal of Industrial and Engineering Chemistry. 2019;77:83-96.
doi:10.1016/j.jiec.2019.04.022 .

Nešović, Katarina, Janković, Ana, Perić-Grujić, Aleksandra, Vukašinović-Sekulić, Maja, Radetić, Tamara, Živković, Ljiljana, Park, Soo Jin, Rhee, Kyong Yop, Mišković-Stanković, Vesna, "Kinetic models of swelling and thermal stability of silver/poly(vinyl alcohol)/chitosan/graphene hydrogels" in Journal of Industrial and Engineering Chemistry, 77 (2019):83-96,
https://doi.org/10.1016/j.jiec.2019.04.022 . .

TY  - CONF
AU  - Mišković-Stanković, Vesna
AU  - Nešović, Katarina
AU  - Janković, Ana
AU  - Radetić, Tamara
AU  - Perić-Grujić, Aleksandra
AU  - Vukašinović-Sekulić, Maja
AU  - Kojić, Vesna
AU  - Yop Rhee, Kyong
PY  - 2019
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/7245
AB  - In recent times, polymer-based hydrogel materials have presented themselves as excellent candidates for
new-generation wound dressings with improved properties, such as high sorption ability, good mechanical
properties and low adhesiveness [1]. Additionally, cross linked hydrogel matrices serve as excellent carriers
for controlled release of antibacterial agents, such as silver nanoparticles (Ag/NPs), which are preferred over
conventional antibiotics due to multi-phase mechanism of action and low susceptibility to induce bacterial
resistance [2]. In this work, we aim to produce novel silver/poly(vinyl alcohol)/chitosan (Ag/PVA/CHI)
hydrogels for wound dressing applications. The electrochemical route for AgNPs synthesis provided facile
and green method for the reduction of Ag+
ions inside the hydrogel matrices, without the need to use toxic
chemical reducing agents [3]. The effect of chitosan content on the synthesis yield, antibacterial properties,
swelling and release kinetics was investigated. The formation of AgNPs was confirmed using UV-visible
spectroscopy through the appearance of plasmon resonant peaks at around 400 nm (Figure 1a), whereas
transmission electron microscopy (TEM) proved the incorporation of both single and polycrystalline spherical
AgNPs with diameters of 5-10 nm (Figure 1b). The swelling and silver release kinetics were investigated in
modified phosphate buffer solutions (pH 7.4) at 37 °C to mimic physiological conditions. The obtained
swelling isotherms and release profiles were fitted with different models to obtain kinetic and diffusion
parameters (Figure 1c). The antibacterial activity was evaluated against Staphylococcus aureus TL and
Escherichia coli ATCC 25922 bacterial strains using an in-suspension test, and non-toxicity of both silvercontaining and silver-free hydrogels was proved by MTT cytotoxicity test. The obtained results confirmed
strong potential of Ag/PVA/CHI hydrogels for biomedical applications.
PB  - International Association of Physical Chemists
C3  - Book of abstracts / 7th Regional Symposium on Electrochemistry – South East Europe & 8th Kurt Schwabe Symposium, Split, Croatia, May 27-30, 2019
T1  - Poly(vinyl alcohol)/chitosan hydrogels with electrochemically synthesized silver nanoparticles for wound dressing applications
SP  - 121
UR  - https://hdl.handle.net/21.15107/rcub_technorep_7245
ER  - 

@conference{
author = "Mišković-Stanković, Vesna and Nešović, Katarina and Janković, Ana and Radetić, Tamara and Perić-Grujić, Aleksandra and Vukašinović-Sekulić, Maja and Kojić, Vesna and Yop Rhee, Kyong",
year = "2019",
abstract = "In recent times, polymer-based hydrogel materials have presented themselves as excellent candidates for
new-generation wound dressings with improved properties, such as high sorption ability, good mechanical
properties and low adhesiveness [1]. Additionally, cross linked hydrogel matrices serve as excellent carriers
for controlled release of antibacterial agents, such as silver nanoparticles (Ag/NPs), which are preferred over
conventional antibiotics due to multi-phase mechanism of action and low susceptibility to induce bacterial
resistance [2]. In this work, we aim to produce novel silver/poly(vinyl alcohol)/chitosan (Ag/PVA/CHI)
hydrogels for wound dressing applications. The electrochemical route for AgNPs synthesis provided facile
and green method for the reduction of Ag+
ions inside the hydrogel matrices, without the need to use toxic
chemical reducing agents [3]. The effect of chitosan content on the synthesis yield, antibacterial properties,
swelling and release kinetics was investigated. The formation of AgNPs was confirmed using UV-visible
spectroscopy through the appearance of plasmon resonant peaks at around 400 nm (Figure 1a), whereas
transmission electron microscopy (TEM) proved the incorporation of both single and polycrystalline spherical
AgNPs with diameters of 5-10 nm (Figure 1b). The swelling and silver release kinetics were investigated in
modified phosphate buffer solutions (pH 7.4) at 37 °C to mimic physiological conditions. The obtained
swelling isotherms and release profiles were fitted with different models to obtain kinetic and diffusion
parameters (Figure 1c). The antibacterial activity was evaluated against Staphylococcus aureus TL and
Escherichia coli ATCC 25922 bacterial strains using an in-suspension test, and non-toxicity of both silvercontaining and silver-free hydrogels was proved by MTT cytotoxicity test. The obtained results confirmed
strong potential of Ag/PVA/CHI hydrogels for biomedical applications.",
publisher = "International Association of Physical Chemists",
journal = "Book of abstracts / 7th Regional Symposium on Electrochemistry – South East Europe & 8th Kurt Schwabe Symposium, Split, Croatia, May 27-30, 2019",
title = "Poly(vinyl alcohol)/chitosan hydrogels with electrochemically synthesized silver nanoparticles for wound dressing applications",
pages = "121",
url = "https://hdl.handle.net/21.15107/rcub_technorep_7245"
}

Mišković-Stanković, V., Nešović, K., Janković, A., Radetić, T., Perić-Grujić, A., Vukašinović-Sekulić, M., Kojić, V.,& Yop Rhee, K.. (2019). Poly(vinyl alcohol)/chitosan hydrogels with electrochemically synthesized silver nanoparticles for wound dressing applications. in Book of abstracts / 7th Regional Symposium on Electrochemistry – South East Europe & 8th Kurt Schwabe Symposium, Split, Croatia, May 27-30, 2019
International Association of Physical Chemists., 121.
https://hdl.handle.net/21.15107/rcub_technorep_7245

Mišković-Stanković V, Nešović K, Janković A, Radetić T, Perić-Grujić A, Vukašinović-Sekulić M, Kojić V, Yop Rhee K. Poly(vinyl alcohol)/chitosan hydrogels with electrochemically synthesized silver nanoparticles for wound dressing applications. in Book of abstracts / 7th Regional Symposium on Electrochemistry – South East Europe & 8th Kurt Schwabe Symposium, Split, Croatia, May 27-30, 2019. 2019;:121.
https://hdl.handle.net/21.15107/rcub_technorep_7245 .

Mišković-Stanković, Vesna, Nešović, Katarina, Janković, Ana, Radetić, Tamara, Perić-Grujić, Aleksandra, Vukašinović-Sekulić, Maja, Kojić, Vesna, Yop Rhee, Kyong, "Poly(vinyl alcohol)/chitosan hydrogels with electrochemically synthesized silver nanoparticles for wound dressing applications" in Book of abstracts / 7th Regional Symposium on Electrochemistry – South East Europe & 8th Kurt Schwabe Symposium, Split, Croatia, May 27-30, 2019 (2019):121,
https://hdl.handle.net/21.15107/rcub_technorep_7245 .

TY  - JOUR
AU  - Nešović, Katarina
AU  - Janković, Ana
AU  - Radetić, Tamara
AU  - Vukašinović-Sekulić, Maja
AU  - Kojić, Vesna
AU  - Živković, Ljiljana
AU  - Perić-Grujić, Aleksandra
AU  - Rhee, Kyong Yop
AU  - Mišković-Stanković, Vesna
PY  - 2019
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4113
AB  - In this work, we provide a facile path for the preparation of wound dressing materials with improved characteristics based on biocompatible chitosan and poly(vinyl alcohol) hydrogels with embedded silver nanoparticles (AgNPs) as a potent antimicrobial agent. The hydrogels were prepared via freezing-thawing method, whereas AgNPs were synthesized via an in situ electrochemical route. The excellent physicochemical properties of the obtained nanocomposite hydrogels were validated using different spectroscopic and microscopic techniques. The formation of sub-10 nm AgNPs was confirmed by UV-visible spectroscopy, dynamic light scattering and transmission electron microscopy. Swelling and silver release profiles were validated using several diffusion models. The hydrogels were proven to be non-cytotoxic using MTT test and possessed powerful antibacterial activity against Staphylococcus aureus and Escherichia coli, as determined by test in suspension, which affirmed their feasibility for wound dressing applications.
PB  - Pergamon-Elsevier Science Ltd, Oxford
T2  - European Polymer Journal
T1  - Chitosan-based hydrogel wound dressings with electrochemically incorporated silver nanoparticles - In vitro study
VL  - 121
DO  - 10.1016/j.eurpolymj.2019.109257
ER  - 

@article{
author = "Nešović, Katarina and Janković, Ana and Radetić, Tamara and Vukašinović-Sekulić, Maja and Kojić, Vesna and Živković, Ljiljana and Perić-Grujić, Aleksandra and Rhee, Kyong Yop and Mišković-Stanković, Vesna",
year = "2019",
abstract = "In this work, we provide a facile path for the preparation of wound dressing materials with improved characteristics based on biocompatible chitosan and poly(vinyl alcohol) hydrogels with embedded silver nanoparticles (AgNPs) as a potent antimicrobial agent. The hydrogels were prepared via freezing-thawing method, whereas AgNPs were synthesized via an in situ electrochemical route. The excellent physicochemical properties of the obtained nanocomposite hydrogels were validated using different spectroscopic and microscopic techniques. The formation of sub-10 nm AgNPs was confirmed by UV-visible spectroscopy, dynamic light scattering and transmission electron microscopy. Swelling and silver release profiles were validated using several diffusion models. The hydrogels were proven to be non-cytotoxic using MTT test and possessed powerful antibacterial activity against Staphylococcus aureus and Escherichia coli, as determined by test in suspension, which affirmed their feasibility for wound dressing applications.",
publisher = "Pergamon-Elsevier Science Ltd, Oxford",
journal = "European Polymer Journal",
title = "Chitosan-based hydrogel wound dressings with electrochemically incorporated silver nanoparticles - In vitro study",
volume = "121",
doi = "10.1016/j.eurpolymj.2019.109257"
}

Nešović, K., Janković, A., Radetić, T., Vukašinović-Sekulić, M., Kojić, V., Živković, L., Perić-Grujić, A., Rhee, K. Y.,& Mišković-Stanković, V.. (2019). Chitosan-based hydrogel wound dressings with electrochemically incorporated silver nanoparticles - In vitro study. in European Polymer Journal
Pergamon-Elsevier Science Ltd, Oxford., 121.
https://doi.org/10.1016/j.eurpolymj.2019.109257

Nešović K, Janković A, Radetić T, Vukašinović-Sekulić M, Kojić V, Živković L, Perić-Grujić A, Rhee KY, Mišković-Stanković V. Chitosan-based hydrogel wound dressings with electrochemically incorporated silver nanoparticles - In vitro study. in European Polymer Journal. 2019;121.
doi:10.1016/j.eurpolymj.2019.109257 .

Nešović, Katarina, Janković, Ana, Radetić, Tamara, Vukašinović-Sekulić, Maja, Kojić, Vesna, Živković, Ljiljana, Perić-Grujić, Aleksandra, Rhee, Kyong Yop, Mišković-Stanković, Vesna, "Chitosan-based hydrogel wound dressings with electrochemically incorporated silver nanoparticles - In vitro study" in European Polymer Journal, 121 (2019),
https://doi.org/10.1016/j.eurpolymj.2019.109257 . .

TY  - CONF
AU  - Nešović, Katarina
AU  - Janković, Ana
AU  - Radetić, Tamara
AU  - Kojić, Vesna
AU  - Mišković-Stanković, Vesna
PY  - 2019
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/7246
AB  - Nauka i inženjerstvo biomaterijala u poslednje vreme pokazuju sve veću težnju ka
pronalaženju novih materijala za obloge za rane, gde su naročito važna poboljšana svojstva
kao što su apsorpciona moć, mehanička svojstva i niska adhezivnost. Umrežene matrice
hidrogelova su odlični potencijalni nosači za kontrolisano otpuštanje antibakterijskih
agenasa, kao što su nanočestice srebra. Hitozan je posebno interesantna komponenta
obloga za rane, zbog svoje prirodne antibakterijske aktivnosti i sposobnosti stabilizacije
nanočestica. Cilj ovog rada je priprema novih obloga za rane na bazi polivinil-alkohola i
hitozana sa elektrohemijski sintetisanim nanočesticama srebra, u obliku hidrogela. Dobijene
su sferne nanočestice srebra, prečnika oko 5-10 nm, što je potvrđeno UV-vidljivom
spektroskopijom i transmisionom elektronskom mikroskopijom. Bubrenje i otpuštanje
srebra je praćeno u fosfatnom puferu koji imitira fiziološke uslove, dok je antibakterijska
aktivnost potvrđena na bakterijskim sojevima Staphylococcus aureus i Escherichia coli.
Dobijeni netoksični hidrogelovi (što je utvrđeno MTT testom) imaju izuzetan potencijal za
primene kao obloge za rane nove generacije.
AB  - Recently, the biomaterials science and engineering fields have seen a shift towards novel
hydrogel materials, especially for wound dressing applications where improved properties,
such as high sorption ability, good mechanical properties and low adhesiveness are of
utmost importance. The cross linked hydrogel matrices are excellent potential carriers for
controlled release of antibacterial agents, such as silver nanoparticles (AgNPs). Chitosan is
an especially attractive option for wound dressing applications, because of its intrinsic
antibacterial activity and the ability to stabilize AgNPs. The aim of this work is the production
of poly(vinyl alcohol) and chitosan based hydrogel matrices with electrochemically
synthesized AgNPs for wound dressing materials applications. The obtained AgNPs were
spherical with 5-10 nm diameters, as confirmed by UV-visible spectroscopy and
transmission electron microscopy. The swelling and release behaviors of AgNP-embedded
hydrogels were evaluated in phosphate buffer, mimicking physiological environment, and
the antibacterial activity was confirmed against both Staphylococcus aureus and Escherichia
coli. The obtained non-toxic hydrogel materials (as affirmed by MTT test) have excellent
potential to be used as novel antibacterial wound dressings.
PB  - Beograd : Srpsko hemijsko društvo
C3  - Kratki izvodi radova / 56. savetovanje Srpskog hemijskog društva , Niš 7. i 8. juni 2019
T1  - Novi materijali za obloge za rane sa elektrohemijski sintetisanim nanočesticama srebra
T1  - Novel wound dressing materials containing electrochemically synthesized silver nanoparticles
SP  - 27
UR  - https://hdl.handle.net/21.15107/rcub_technorep_7246
ER  - 

@conference{
author = "Nešović, Katarina and Janković, Ana and Radetić, Tamara and Kojić, Vesna and Mišković-Stanković, Vesna",
year = "2019",
abstract = "Nauka i inženjerstvo biomaterijala u poslednje vreme pokazuju sve veću težnju ka
pronalaženju novih materijala za obloge za rane, gde su naročito važna poboljšana svojstva
kao što su apsorpciona moć, mehanička svojstva i niska adhezivnost. Umrežene matrice
hidrogelova su odlični potencijalni nosači za kontrolisano otpuštanje antibakterijskih
agenasa, kao što su nanočestice srebra. Hitozan je posebno interesantna komponenta
obloga za rane, zbog svoje prirodne antibakterijske aktivnosti i sposobnosti stabilizacije
nanočestica. Cilj ovog rada je priprema novih obloga za rane na bazi polivinil-alkohola i
hitozana sa elektrohemijski sintetisanim nanočesticama srebra, u obliku hidrogela. Dobijene
su sferne nanočestice srebra, prečnika oko 5-10 nm, što je potvrđeno UV-vidljivom
spektroskopijom i transmisionom elektronskom mikroskopijom. Bubrenje i otpuštanje
srebra je praćeno u fosfatnom puferu koji imitira fiziološke uslove, dok je antibakterijska
aktivnost potvrđena na bakterijskim sojevima Staphylococcus aureus i Escherichia coli.
Dobijeni netoksični hidrogelovi (što je utvrđeno MTT testom) imaju izuzetan potencijal za
primene kao obloge za rane nove generacije., Recently, the biomaterials science and engineering fields have seen a shift towards novel
hydrogel materials, especially for wound dressing applications where improved properties,
such as high sorption ability, good mechanical properties and low adhesiveness are of
utmost importance. The cross linked hydrogel matrices are excellent potential carriers for
controlled release of antibacterial agents, such as silver nanoparticles (AgNPs). Chitosan is
an especially attractive option for wound dressing applications, because of its intrinsic
antibacterial activity and the ability to stabilize AgNPs. The aim of this work is the production
of poly(vinyl alcohol) and chitosan based hydrogel matrices with electrochemically
synthesized AgNPs for wound dressing materials applications. The obtained AgNPs were
spherical with 5-10 nm diameters, as confirmed by UV-visible spectroscopy and
transmission electron microscopy. The swelling and release behaviors of AgNP-embedded
hydrogels were evaluated in phosphate buffer, mimicking physiological environment, and
the antibacterial activity was confirmed against both Staphylococcus aureus and Escherichia
coli. The obtained non-toxic hydrogel materials (as affirmed by MTT test) have excellent
potential to be used as novel antibacterial wound dressings.",
publisher = "Beograd : Srpsko hemijsko društvo",
journal = "Kratki izvodi radova / 56. savetovanje Srpskog hemijskog društva , Niš 7. i 8. juni 2019",
title = "Novi materijali za obloge za rane sa elektrohemijski sintetisanim nanočesticama srebra, Novel wound dressing materials containing electrochemically synthesized silver nanoparticles",
pages = "27",
url = "https://hdl.handle.net/21.15107/rcub_technorep_7246"
}

Nešović, K., Janković, A., Radetić, T., Kojić, V.,& Mišković-Stanković, V.. (2019). Novi materijali za obloge za rane sa elektrohemijski sintetisanim nanočesticama srebra. in Kratki izvodi radova / 56. savetovanje Srpskog hemijskog društva , Niš 7. i 8. juni 2019
Beograd : Srpsko hemijsko društvo., 27.
https://hdl.handle.net/21.15107/rcub_technorep_7246

Nešović K, Janković A, Radetić T, Kojić V, Mišković-Stanković V. Novi materijali za obloge za rane sa elektrohemijski sintetisanim nanočesticama srebra. in Kratki izvodi radova / 56. savetovanje Srpskog hemijskog društva , Niš 7. i 8. juni 2019. 2019;:27.
https://hdl.handle.net/21.15107/rcub_technorep_7246 .

Nešović, Katarina, Janković, Ana, Radetić, Tamara, Kojić, Vesna, Mišković-Stanković, Vesna, "Novi materijali za obloge za rane sa elektrohemijski sintetisanim nanočesticama srebra" in Kratki izvodi radova / 56. savetovanje Srpskog hemijskog društva , Niš 7. i 8. juni 2019 (2019):27,
https://hdl.handle.net/21.15107/rcub_technorep_7246 .

TY  - JOUR
AU  - Mittal, Garima
AU  - Nešović, Katarina
AU  - Rhee, Kyong Yop
AU  - Mišković-Stanković, Vesna
PY  - 2019
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4134
AB  - In this study, the corrosion behaviour of carbon nanotubes (CNTs) coated basalt fibre (BF) (BFCNTs) obtained by chemical vapour deposition (CVD), was studied. During CVD, the CNTs were grown on BF, (a) at different growth temperatures and (b) for different growth times. The physicochemical measurements were performed using X-ray diffraction, Raman spectroscopy, and field-emission scanning electron microscopy. The corrosion performances were investigated using electrochemical impedance spectroscopy (EIS), potentiodynamic sweep (PDS), linear polarization resistance (LPR) and weight loss measurements. The BFCNT prepared at 650 degrees C for 120 min exhibited the best corrosion stability during the prolonged exposure to 0.1 M NaCl electrolyte. The outcomes of this study would be useful in designing the carbon nanotubes coated basalt fibre with the best corrosion resistance.
PB  - Elsevier Sci Ltd, Oxford
T2  - Composites Part B-Engineering
T1  - Investigation of corrosion behaviour of carbon nanotubes coated basalt fabric as a reinforcement material
VL  - 178
DO  - 10.1016/j.compositesb.2019.107493
ER  - 

@article{
author = "Mittal, Garima and Nešović, Katarina and Rhee, Kyong Yop and Mišković-Stanković, Vesna",
year = "2019",
abstract = "In this study, the corrosion behaviour of carbon nanotubes (CNTs) coated basalt fibre (BF) (BFCNTs) obtained by chemical vapour deposition (CVD), was studied. During CVD, the CNTs were grown on BF, (a) at different growth temperatures and (b) for different growth times. The physicochemical measurements were performed using X-ray diffraction, Raman spectroscopy, and field-emission scanning electron microscopy. The corrosion performances were investigated using electrochemical impedance spectroscopy (EIS), potentiodynamic sweep (PDS), linear polarization resistance (LPR) and weight loss measurements. The BFCNT prepared at 650 degrees C for 120 min exhibited the best corrosion stability during the prolonged exposure to 0.1 M NaCl electrolyte. The outcomes of this study would be useful in designing the carbon nanotubes coated basalt fibre with the best corrosion resistance.",
publisher = "Elsevier Sci Ltd, Oxford",
journal = "Composites Part B-Engineering",
title = "Investigation of corrosion behaviour of carbon nanotubes coated basalt fabric as a reinforcement material",
volume = "178",
doi = "10.1016/j.compositesb.2019.107493"
}

Mittal, G., Nešović, K., Rhee, K. Y.,& Mišković-Stanković, V.. (2019). Investigation of corrosion behaviour of carbon nanotubes coated basalt fabric as a reinforcement material. in Composites Part B-Engineering
Elsevier Sci Ltd, Oxford., 178.
https://doi.org/10.1016/j.compositesb.2019.107493

Mittal G, Nešović K, Rhee KY, Mišković-Stanković V. Investigation of corrosion behaviour of carbon nanotubes coated basalt fabric as a reinforcement material. in Composites Part B-Engineering. 2019;178.
doi:10.1016/j.compositesb.2019.107493 .

Mittal, Garima, Nešović, Katarina, Rhee, Kyong Yop, Mišković-Stanković, Vesna, "Investigation of corrosion behaviour of carbon nanotubes coated basalt fabric as a reinforcement material" in Composites Part B-Engineering, 178 (2019),
https://doi.org/10.1016/j.compositesb.2019.107493 . .

TY  - CONF
AU  - Nešović, Katarina
AU  - Janković, Ana
AU  - Vukašinović-Sekulić, Maja
AU  - Perić-Grujić, Aleksandra
AU  - Mišković-Stanković, Vesna
PY  - 2018
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/7386
AB  - In this work, we prepared hydrogels based on PVA, CHI and Gr, and used them
as a porous matrix to synthesize silver nanoparticles by an in situ electrochemical
method [3,4]. The hydrogels were prepared from PVA/CHI/Gr colloid dispersions
using a simple and effective freezing-thawing method for gelation, without the use
of chemical cross linkers. The hydrogels were then swollen in AgNO3 solution to
saturate with Ag+ ions and subsequently subjected to constant-voltage electrical
current, to reduce silver ions and to obtain AgNPs. This electrochemical method
is fast and green, as there is no need for the use of any (potentially toxic) chemical
cross linkers and reducing agents, rendering the final product non-toxic and safe for
medical applications.
PB  - Belgrade : Serbian Academy of Sciences and Arts
C3  - Program ; Book of Abstracts / First International Conference on Electron Microscopy of Nanostructures ELMINA 2018, August 27-29, 2018, Belgrade, Serbia = Прва међународна конференција о електронској микроскопији наноструктура ELMINA 2018, 27-29 август 2018. Београд, Србија
T1  - Nanocomposite Hydrogels Based on Poly(vinyl alcohol) and Chitosan with Silver Nanoparticles and Graphene Aimed for Wound Dressing Applications
EP  - 242
SP  - 240
UR  - https://hdl.handle.net/21.15107/rcub_technorep_7386
ER  - 

@conference{
author = "Nešović, Katarina and Janković, Ana and Vukašinović-Sekulić, Maja and Perić-Grujić, Aleksandra and Mišković-Stanković, Vesna",
year = "2018",
abstract = "In this work, we prepared hydrogels based on PVA, CHI and Gr, and used them
as a porous matrix to synthesize silver nanoparticles by an in situ electrochemical
method [3,4]. The hydrogels were prepared from PVA/CHI/Gr colloid dispersions
using a simple and effective freezing-thawing method for gelation, without the use
of chemical cross linkers. The hydrogels were then swollen in AgNO3 solution to
saturate with Ag+ ions and subsequently subjected to constant-voltage electrical
current, to reduce silver ions and to obtain AgNPs. This electrochemical method
is fast and green, as there is no need for the use of any (potentially toxic) chemical
cross linkers and reducing agents, rendering the final product non-toxic and safe for
medical applications.",
publisher = "Belgrade : Serbian Academy of Sciences and Arts",
journal = "Program ; Book of Abstracts / First International Conference on Electron Microscopy of Nanostructures ELMINA 2018, August 27-29, 2018, Belgrade, Serbia = Прва међународна конференција о електронској микроскопији наноструктура ELMINA 2018, 27-29 август 2018. Београд, Србија",
title = "Nanocomposite Hydrogels Based on Poly(vinyl alcohol) and Chitosan with Silver Nanoparticles and Graphene Aimed for Wound Dressing Applications",
pages = "242-240",
url = "https://hdl.handle.net/21.15107/rcub_technorep_7386"
}

Nešović, K., Janković, A., Vukašinović-Sekulić, M., Perić-Grujić, A.,& Mišković-Stanković, V.. (2018). Nanocomposite Hydrogels Based on Poly(vinyl alcohol) and Chitosan with Silver Nanoparticles and Graphene Aimed for Wound Dressing Applications. in Program ; Book of Abstracts / First International Conference on Electron Microscopy of Nanostructures ELMINA 2018, August 27-29, 2018, Belgrade, Serbia = Прва међународна конференција о електронској микроскопији наноструктура ELMINA 2018, 27-29 август 2018. Београд, Србија
Belgrade : Serbian Academy of Sciences and Arts., 240-242.
https://hdl.handle.net/21.15107/rcub_technorep_7386

Nešović K, Janković A, Vukašinović-Sekulić M, Perić-Grujić A, Mišković-Stanković V. Nanocomposite Hydrogels Based on Poly(vinyl alcohol) and Chitosan with Silver Nanoparticles and Graphene Aimed for Wound Dressing Applications. in Program ; Book of Abstracts / First International Conference on Electron Microscopy of Nanostructures ELMINA 2018, August 27-29, 2018, Belgrade, Serbia = Прва међународна конференција о електронској микроскопији наноструктура ELMINA 2018, 27-29 август 2018. Београд, Србија. 2018;:240-242.
https://hdl.handle.net/21.15107/rcub_technorep_7386 .

Nešović, Katarina, Janković, Ana, Vukašinović-Sekulić, Maja, Perić-Grujić, Aleksandra, Mišković-Stanković, Vesna, "Nanocomposite Hydrogels Based on Poly(vinyl alcohol) and Chitosan with Silver Nanoparticles and Graphene Aimed for Wound Dressing Applications" in Program ; Book of Abstracts / First International Conference on Electron Microscopy of Nanostructures ELMINA 2018, August 27-29, 2018, Belgrade, Serbia = Прва међународна конференција о електронској микроскопији наноструктура ELMINA 2018, 27-29 август 2018. Београд, Србија (2018):240-242,
https://hdl.handle.net/21.15107/rcub_technorep_7386 .

TY  - JOUR
AU  - Lužajić-Božinovski, Tijana
AU  - Marković, Danica
AU  - Todorović, Vera
AU  - Prokić, Bogomir Bolka
AU  - Milošević, Ivan
AU  - Drndarević, Neda
AU  - Nešović, Katarina
AU  - Kyong, Yop Rhee
AU  - Mišković-Stanković, Vesna
PY  - 2018
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3924
AB  - In this paper, we have shown for the first time the soft tissue response of novel silver/poly(vinyl alcohol)/graphene (Ag/PVA/Gr) and silver/poly(vinyl alcohol)/chitosan/graphene (Ag/PVA/CHI/Gr) nanocomposite hydrogels aimed for medical applications. These novel hydrogels were produced by in situ electrochemical synthesis of silver nanoparticles in the polymer matrices as described in our previously published works. Both Ag/PVA/Gr and Ag/PVA/CHI/Gr, as well as controls Ag/PVA, Ag/PVA/CHI and commercial Suprasorb
PB  - Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd
T2  - Acta Veterinaria, Beograd
T1  - In vivo investigation of soft tissue response of novel silver/poly(vinyl alcohol)/ graphene and silver/poly(vinyl alcohol)/chitosan/graphene hydrogels aimed for medical applications - the first experience
EP  - 339
IS  - 3
SP  - 321
VL  - 68
DO  - 10.2478/acve-2018-0027
ER  - 

@article{
author = "Lužajić-Božinovski, Tijana and Marković, Danica and Todorović, Vera and Prokić, Bogomir Bolka and Milošević, Ivan and Drndarević, Neda and Nešović, Katarina and Kyong, Yop Rhee and Mišković-Stanković, Vesna",
year = "2018",
abstract = "In this paper, we have shown for the first time the soft tissue response of novel silver/poly(vinyl alcohol)/graphene (Ag/PVA/Gr) and silver/poly(vinyl alcohol)/chitosan/graphene (Ag/PVA/CHI/Gr) nanocomposite hydrogels aimed for medical applications. These novel hydrogels were produced by in situ electrochemical synthesis of silver nanoparticles in the polymer matrices as described in our previously published works. Both Ag/PVA/Gr and Ag/PVA/CHI/Gr, as well as controls Ag/PVA, Ag/PVA/CHI and commercial Suprasorb",
publisher = "Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd",
journal = "Acta Veterinaria, Beograd",
title = "In vivo investigation of soft tissue response of novel silver/poly(vinyl alcohol)/ graphene and silver/poly(vinyl alcohol)/chitosan/graphene hydrogels aimed for medical applications - the first experience",
pages = "339-321",
number = "3",
volume = "68",
doi = "10.2478/acve-2018-0027"
}

Lužajić-Božinovski, T., Marković, D., Todorović, V., Prokić, B. B., Milošević, I., Drndarević, N., Nešović, K., Kyong, Y. R.,& Mišković-Stanković, V.. (2018). In vivo investigation of soft tissue response of novel silver/poly(vinyl alcohol)/ graphene and silver/poly(vinyl alcohol)/chitosan/graphene hydrogels aimed for medical applications - the first experience. in Acta Veterinaria, Beograd
Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd., 68(3), 321-339.
https://doi.org/10.2478/acve-2018-0027

Lužajić-Božinovski T, Marković D, Todorović V, Prokić BB, Milošević I, Drndarević N, Nešović K, Kyong YR, Mišković-Stanković V. In vivo investigation of soft tissue response of novel silver/poly(vinyl alcohol)/ graphene and silver/poly(vinyl alcohol)/chitosan/graphene hydrogels aimed for medical applications - the first experience. in Acta Veterinaria, Beograd. 2018;68(3):321-339.
doi:10.2478/acve-2018-0027 .

Lužajić-Božinovski, Tijana, Marković, Danica, Todorović, Vera, Prokić, Bogomir Bolka, Milošević, Ivan, Drndarević, Neda, Nešović, Katarina, Kyong, Yop Rhee, Mišković-Stanković, Vesna, "In vivo investigation of soft tissue response of novel silver/poly(vinyl alcohol)/ graphene and silver/poly(vinyl alcohol)/chitosan/graphene hydrogels aimed for medical applications - the first experience" in Acta Veterinaria, Beograd, 68, no. 3 (2018):321-339,
https://doi.org/10.2478/acve-2018-0027 . .

TY  - JOUR
AU  - Nešović, Katarina
AU  - Janković, Ana
AU  - Kojić, Vesna
AU  - Vukašinović-Sekulić, Maja
AU  - Perić-Grujić, Aleksandra
AU  - Rhee, Kyong Yop
AU  - Mišković-Stanković, Vesna
PY  - 2018
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3942
AB  - This study presents the synthesis of novel silver/poly(vinyl alcohol)/chitosan/graphene (Ag/PVA/CHI/Gr) nanocomposite hydrogels by in situ electrochemical reduction of silver ions in the hydrogel matrix and their thorough characterization by UV-visible and Raman spectroscopies, field-emission scanning electron microscopy (FE-SEM), X-ray photoelectron spectroscopy (XPS), and silver release measurements. The influence of chitosan content on the incorporation and stabilization of silver nanoparticles (AgNPs) was investigated, and we found that hydrogels with higher chitosan content contain higher amounts of AgNPs. In addition, the cytotoxicity and antibacterial activity of Ag/PVA/CHI/Gr nanocomposite hydrogels were evaluated. Based on in vitro investigations, the obtained materials exhibit diffusion-controlled release profiles over 28 days, strong antibacterial activity against Staphylococcus aureus and Escherichia coli bacterial strains, and no cytotoxicity toward human and mice fibroblast cell lines.
PB  - Elsevier Sci Ltd, Oxford
T2  - Composites Part B-Engineering
T1  - Silver/poly(vinyl alcohol)/chitosan/graphene hydrogels - Synthesis, biological and physicochemical properties and silver release kinetics
EP  - 185
SP  - 175
VL  - 154
DO  - 10.1016/j.compositesb.2018.08.005
ER  - 

@article{
author = "Nešović, Katarina and Janković, Ana and Kojić, Vesna and Vukašinović-Sekulić, Maja and Perić-Grujić, Aleksandra and Rhee, Kyong Yop and Mišković-Stanković, Vesna",
year = "2018",
abstract = "This study presents the synthesis of novel silver/poly(vinyl alcohol)/chitosan/graphene (Ag/PVA/CHI/Gr) nanocomposite hydrogels by in situ electrochemical reduction of silver ions in the hydrogel matrix and their thorough characterization by UV-visible and Raman spectroscopies, field-emission scanning electron microscopy (FE-SEM), X-ray photoelectron spectroscopy (XPS), and silver release measurements. The influence of chitosan content on the incorporation and stabilization of silver nanoparticles (AgNPs) was investigated, and we found that hydrogels with higher chitosan content contain higher amounts of AgNPs. In addition, the cytotoxicity and antibacterial activity of Ag/PVA/CHI/Gr nanocomposite hydrogels were evaluated. Based on in vitro investigations, the obtained materials exhibit diffusion-controlled release profiles over 28 days, strong antibacterial activity against Staphylococcus aureus and Escherichia coli bacterial strains, and no cytotoxicity toward human and mice fibroblast cell lines.",
publisher = "Elsevier Sci Ltd, Oxford",
journal = "Composites Part B-Engineering",
title = "Silver/poly(vinyl alcohol)/chitosan/graphene hydrogels - Synthesis, biological and physicochemical properties and silver release kinetics",
pages = "185-175",
volume = "154",
doi = "10.1016/j.compositesb.2018.08.005"
}

Nešović, K., Janković, A., Kojić, V., Vukašinović-Sekulić, M., Perić-Grujić, A., Rhee, K. Y.,& Mišković-Stanković, V.. (2018). Silver/poly(vinyl alcohol)/chitosan/graphene hydrogels - Synthesis, biological and physicochemical properties and silver release kinetics. in Composites Part B-Engineering
Elsevier Sci Ltd, Oxford., 154, 175-185.
https://doi.org/10.1016/j.compositesb.2018.08.005

Nešović K, Janković A, Kojić V, Vukašinović-Sekulić M, Perić-Grujić A, Rhee KY, Mišković-Stanković V. Silver/poly(vinyl alcohol)/chitosan/graphene hydrogels - Synthesis, biological and physicochemical properties and silver release kinetics. in Composites Part B-Engineering. 2018;154:175-185.
doi:10.1016/j.compositesb.2018.08.005 .

Nešović, Katarina, Janković, Ana, Kojić, Vesna, Vukašinović-Sekulić, Maja, Perić-Grujić, Aleksandra, Rhee, Kyong Yop, Mišković-Stanković, Vesna, "Silver/poly(vinyl alcohol)/chitosan/graphene hydrogels - Synthesis, biological and physicochemical properties and silver release kinetics" in Composites Part B-Engineering, 154 (2018):175-185,
https://doi.org/10.1016/j.compositesb.2018.08.005 . .

TY  - JOUR
AU  - Naghdi, Samira
AU  - Nešović, Katarina
AU  - Mišković-Stanković, Vesna
AU  - Rhee, Kyong Yop
PY  - 2018
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3976
AB  - In this work, we present the results of electrochemical, Raman, FE-SEM/EDS, and XPS studies of graphene coatings deposited by chemical vapour deposition at atmospheric pressure on Mo foil and Pt-coated Mo foil as catalysts. The results showed that the graphene coating synthesized on Pt-coated molybdenum foil was bi-layer and had fewer defects, while the graphene coating on Mo foil was few-layer with more defects. The corrosion studies indicated that both graphene coatings on bare Mo and Pt-coated Mo exhibited good protective properties and can act as a barrier against corrosion in 0.1 M NaCl.
PB  - Pergamon-Elsevier Science Ltd, Oxford
T2  - Corrosion Science
T1  - Comprehensive electrochemical study on corrosion performance of graphene coatings deposited by chemical vapour deposition at atmospheric pressure on platinum-coated molybdenum foil
EP  - 44
SP  - 31
VL  - 130
DO  - 10.1016/j.corsci.2017.10.021
ER  - 

@article{
author = "Naghdi, Samira and Nešović, Katarina and Mišković-Stanković, Vesna and Rhee, Kyong Yop",
year = "2018",
abstract = "In this work, we present the results of electrochemical, Raman, FE-SEM/EDS, and XPS studies of graphene coatings deposited by chemical vapour deposition at atmospheric pressure on Mo foil and Pt-coated Mo foil as catalysts. The results showed that the graphene coating synthesized on Pt-coated molybdenum foil was bi-layer and had fewer defects, while the graphene coating on Mo foil was few-layer with more defects. The corrosion studies indicated that both graphene coatings on bare Mo and Pt-coated Mo exhibited good protective properties and can act as a barrier against corrosion in 0.1 M NaCl.",
publisher = "Pergamon-Elsevier Science Ltd, Oxford",
journal = "Corrosion Science",
title = "Comprehensive electrochemical study on corrosion performance of graphene coatings deposited by chemical vapour deposition at atmospheric pressure on platinum-coated molybdenum foil",
pages = "44-31",
volume = "130",
doi = "10.1016/j.corsci.2017.10.021"
}

Naghdi, S., Nešović, K., Mišković-Stanković, V.,& Rhee, K. Y.. (2018). Comprehensive electrochemical study on corrosion performance of graphene coatings deposited by chemical vapour deposition at atmospheric pressure on platinum-coated molybdenum foil. in Corrosion Science
Pergamon-Elsevier Science Ltd, Oxford., 130, 31-44.
https://doi.org/10.1016/j.corsci.2017.10.021

Naghdi S, Nešović K, Mišković-Stanković V, Rhee KY. Comprehensive electrochemical study on corrosion performance of graphene coatings deposited by chemical vapour deposition at atmospheric pressure on platinum-coated molybdenum foil. in Corrosion Science. 2018;130:31-44.
doi:10.1016/j.corsci.2017.10.021 .

Naghdi, Samira, Nešović, Katarina, Mišković-Stanković, Vesna, Rhee, Kyong Yop, "Comprehensive electrochemical study on corrosion performance of graphene coatings deposited by chemical vapour deposition at atmospheric pressure on platinum-coated molybdenum foil" in Corrosion Science, 130 (2018):31-44,
https://doi.org/10.1016/j.corsci.2017.10.021 . .

TY  - JOUR
AU  - Abudabbus, Mohamed M.
AU  - Jevremović, Ivana
AU  - Nešović, Katarina
AU  - Perić-Grujić, Aleksandra
AU  - Rhee, Kyong Yop
AU  - Mišković-Stanković, Vesna
PY  - 2018
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4041
AB  - This paper presents silver/poly(vinyl alcohol) (Ag/PVA) and silver/poly(vinyl alcohol)/graphene (Ag/PVA/Gr) composites prepared by the immobilization of silver nanoparticles (AgNPs) in PVA and PVA/Gr hydrogel discs previously cross linked by the freezing/thawing method. The AgNPs inside the hydrogel matrices were synthesized following an innovative in situ method of electrochemical reduction of Ag+ ions within PVA and PVA/Gr hydrogel discs. In addition, the novel materials introduced here were characterized by UV-visible spectroscopy, cyclic voltammetry, Raman spectroscopy, X-ray diffraction, Fourier transform infrared spectroscopy, silver release measurements, and thermogravimetric analysis. The effective immobilization of the AgNPs inside the PVA and PVA/Gr hydrogel networks was achieved by their bonding with the exposed hydroxyl groups in PVA. Also, the incorporation of graphene into the PVA matrix and the bonding between PVA molecules and incorporated graphene sheets improves thermal stability of Ag/PVA/Gr and prevents aggregation and growth of AgNPs as observed by Fourier transform infrared spectroscopy and field emission scanning electron microscopy.
PB  - Elsevier Sci Ltd, Oxford
T2  - Composites Part B-Engineering
T1  - In situ electrochemical synthesis of silver-doped poly(vinyl alcohol)/graphene composite hydrogels and their physico-chemical and thermal properties
EP  - 107
SP  - 99
VL  - 140
DO  - 10.1016/j.compositesb.2017.12.017
ER  - 

@article{
author = "Abudabbus, Mohamed M. and Jevremović, Ivana and Nešović, Katarina and Perić-Grujić, Aleksandra and Rhee, Kyong Yop and Mišković-Stanković, Vesna",
year = "2018",
abstract = "This paper presents silver/poly(vinyl alcohol) (Ag/PVA) and silver/poly(vinyl alcohol)/graphene (Ag/PVA/Gr) composites prepared by the immobilization of silver nanoparticles (AgNPs) in PVA and PVA/Gr hydrogel discs previously cross linked by the freezing/thawing method. The AgNPs inside the hydrogel matrices were synthesized following an innovative in situ method of electrochemical reduction of Ag+ ions within PVA and PVA/Gr hydrogel discs. In addition, the novel materials introduced here were characterized by UV-visible spectroscopy, cyclic voltammetry, Raman spectroscopy, X-ray diffraction, Fourier transform infrared spectroscopy, silver release measurements, and thermogravimetric analysis. The effective immobilization of the AgNPs inside the PVA and PVA/Gr hydrogel networks was achieved by their bonding with the exposed hydroxyl groups in PVA. Also, the incorporation of graphene into the PVA matrix and the bonding between PVA molecules and incorporated graphene sheets improves thermal stability of Ag/PVA/Gr and prevents aggregation and growth of AgNPs as observed by Fourier transform infrared spectroscopy and field emission scanning electron microscopy.",
publisher = "Elsevier Sci Ltd, Oxford",
journal = "Composites Part B-Engineering",
title = "In situ electrochemical synthesis of silver-doped poly(vinyl alcohol)/graphene composite hydrogels and their physico-chemical and thermal properties",
pages = "107-99",
volume = "140",
doi = "10.1016/j.compositesb.2017.12.017"
}

Abudabbus, M. M., Jevremović, I., Nešović, K., Perić-Grujić, A., Rhee, K. Y.,& Mišković-Stanković, V.. (2018). In situ electrochemical synthesis of silver-doped poly(vinyl alcohol)/graphene composite hydrogels and their physico-chemical and thermal properties. in Composites Part B-Engineering
Elsevier Sci Ltd, Oxford., 140, 99-107.
https://doi.org/10.1016/j.compositesb.2017.12.017

Abudabbus MM, Jevremović I, Nešović K, Perić-Grujić A, Rhee KY, Mišković-Stanković V. In situ electrochemical synthesis of silver-doped poly(vinyl alcohol)/graphene composite hydrogels and their physico-chemical and thermal properties. in Composites Part B-Engineering. 2018;140:99-107.
doi:10.1016/j.compositesb.2017.12.017 .

Abudabbus, Mohamed M., Jevremović, Ivana, Nešović, Katarina, Perić-Grujić, Aleksandra, Rhee, Kyong Yop, Mišković-Stanković, Vesna, "In situ electrochemical synthesis of silver-doped poly(vinyl alcohol)/graphene composite hydrogels and their physico-chemical and thermal properties" in Composites Part B-Engineering, 140 (2018):99-107,
https://doi.org/10.1016/j.compositesb.2017.12.017 . .

TY  - JOUR
AU  - Nešović, Katarina
AU  - Abudabbus, Mohamed M.
AU  - Rhee, Kyong Yop
AU  - Mišković-Stanković, Vesna
PY  - 2017
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3620
AB  - In this work, composite hydrogel consisting of poly(vinyl alcohol), graphene and silver nanoparticles, (Ag/PVA/Gr), was prepared by the immobilization of silver nanoparticles (AgNPs) in PVA/Gr hydrogel matrix in two steps. The first step was cross linking of the PVA/Gr colloid solution by the freezing/thawing method, while in the second step, in situ electrochemical method was used to incorporate AgNPs inside the PVA/Gr hydrogel matrix. We used UV-vis spectroscopy, cyclic voltammetry, Raman spectroscopy, DSC analysis, as well as test of cytotoxicity and antibacterial activity, to characterize obtained Ag/PVA/Gr hydrogel. It was shown that graphene- based composite hydrogel with incorporated AgNPs is non toxic biomaterial with antibacterial activity, with a potential for use in biomedical purposes.
PB  - Croatian Chemical Soc, Zagreb
T2  - Croatica Chemica Acta
T1  - Graphene Based Composite Hydrogel for Biomedical Applications
EP  - 213
IS  - 2
SP  - 207
VL  - 90
DO  - 10.5562/cca3133
ER  - 

@article{
author = "Nešović, Katarina and Abudabbus, Mohamed M. and Rhee, Kyong Yop and Mišković-Stanković, Vesna",
year = "2017",
abstract = "In this work, composite hydrogel consisting of poly(vinyl alcohol), graphene and silver nanoparticles, (Ag/PVA/Gr), was prepared by the immobilization of silver nanoparticles (AgNPs) in PVA/Gr hydrogel matrix in two steps. The first step was cross linking of the PVA/Gr colloid solution by the freezing/thawing method, while in the second step, in situ electrochemical method was used to incorporate AgNPs inside the PVA/Gr hydrogel matrix. We used UV-vis spectroscopy, cyclic voltammetry, Raman spectroscopy, DSC analysis, as well as test of cytotoxicity and antibacterial activity, to characterize obtained Ag/PVA/Gr hydrogel. It was shown that graphene- based composite hydrogel with incorporated AgNPs is non toxic biomaterial with antibacterial activity, with a potential for use in biomedical purposes.",
publisher = "Croatian Chemical Soc, Zagreb",
journal = "Croatica Chemica Acta",
title = "Graphene Based Composite Hydrogel for Biomedical Applications",
pages = "213-207",
number = "2",
volume = "90",
doi = "10.5562/cca3133"
}

Nešović, K., Abudabbus, M. M., Rhee, K. Y.,& Mišković-Stanković, V.. (2017). Graphene Based Composite Hydrogel for Biomedical Applications. in Croatica Chemica Acta
Croatian Chemical Soc, Zagreb., 90(2), 207-213.
https://doi.org/10.5562/cca3133

Nešović K, Abudabbus MM, Rhee KY, Mišković-Stanković V. Graphene Based Composite Hydrogel for Biomedical Applications. in Croatica Chemica Acta. 2017;90(2):207-213.
doi:10.5562/cca3133 .

Nešović, Katarina, Abudabbus, Mohamed M., Rhee, Kyong Yop, Mišković-Stanković, Vesna, "Graphene Based Composite Hydrogel for Biomedical Applications" in Croatica Chemica Acta, 90, no. 2 (2017):207-213,
https://doi.org/10.5562/cca3133 . .

TY  - JOUR
AU  - Nešović, Katarina
AU  - Kojić, Vesna
AU  - Rhee, Kyong Yop
AU  - Mišković-Stanković, Vesna
PY  - 2017
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3623
AB  - In this paper, novel silver-doped poly(vinyl alcohol)/chitosan/graphene (Ag/PVA/CHI/Gr) nanocomposites were produced by in situ electrochemical synthesis of silver nanoparticles in the polyvinyl alcohol/chitosan/graphene (PVA/CHI/Gr) matrix. The presence of silver nanoparticles, as an antibacterial agent, was proven by ultraviolet-visible spectroscopy. The synthesized nanocomposites were further characterized by scanning electron microscopy, Raman spectroscopy, and x-ray photoelectron spectroscopy. Thermal stability was investigated using thermogravimetric analysis, while electrochemical properties of PVA/CHI/Gr and Ag/PVA/CHI/Gr were examined by cyclic voltammetry. It was suggested that silver nanoparticles were embedded in the PVA/CHI/Gr matrix as a result of chemical bonding with hydroxyl groups of PVA and amine and hydroxyl groups of CHI, and have improved thermal stability of PVA/CHI/Gr hydrogel.
PB  - Natl Assoc Corrosion Eng, Houston
T2  - Corrosion
T1  - Electrochemical Synthesis and Characterization of Silver Doped Poly(vinyl alcohol)/Chitosan Hydrogels
IS  - 12
VL  - 73
DO  - 10.5006/2507
ER  - 

@article{
author = "Nešović, Katarina and Kojić, Vesna and Rhee, Kyong Yop and Mišković-Stanković, Vesna",
year = "2017",
abstract = "In this paper, novel silver-doped poly(vinyl alcohol)/chitosan/graphene (Ag/PVA/CHI/Gr) nanocomposites were produced by in situ electrochemical synthesis of silver nanoparticles in the polyvinyl alcohol/chitosan/graphene (PVA/CHI/Gr) matrix. The presence of silver nanoparticles, as an antibacterial agent, was proven by ultraviolet-visible spectroscopy. The synthesized nanocomposites were further characterized by scanning electron microscopy, Raman spectroscopy, and x-ray photoelectron spectroscopy. Thermal stability was investigated using thermogravimetric analysis, while electrochemical properties of PVA/CHI/Gr and Ag/PVA/CHI/Gr were examined by cyclic voltammetry. It was suggested that silver nanoparticles were embedded in the PVA/CHI/Gr matrix as a result of chemical bonding with hydroxyl groups of PVA and amine and hydroxyl groups of CHI, and have improved thermal stability of PVA/CHI/Gr hydrogel.",
publisher = "Natl Assoc Corrosion Eng, Houston",
journal = "Corrosion",
title = "Electrochemical Synthesis and Characterization of Silver Doped Poly(vinyl alcohol)/Chitosan Hydrogels",
number = "12",
volume = "73",
doi = "10.5006/2507"
}

Nešović, K., Kojić, V., Rhee, K. Y.,& Mišković-Stanković, V.. (2017). Electrochemical Synthesis and Characterization of Silver Doped Poly(vinyl alcohol)/Chitosan Hydrogels. in Corrosion
Natl Assoc Corrosion Eng, Houston., 73(12).
https://doi.org/10.5006/2507

Nešović K, Kojić V, Rhee KY, Mišković-Stanković V. Electrochemical Synthesis and Characterization of Silver Doped Poly(vinyl alcohol)/Chitosan Hydrogels. in Corrosion. 2017;73(12).
doi:10.5006/2507 .

Nešović, Katarina, Kojić, Vesna, Rhee, Kyong Yop, Mišković-Stanković, Vesna, "Electrochemical Synthesis and Characterization of Silver Doped Poly(vinyl alcohol)/Chitosan Hydrogels" in Corrosion, 73, no. 12 (2017),
https://doi.org/10.5006/2507 . .