TY  - JOUR
AU  - Jevtić, Dubravka R.
AU  - Avramov-Ivić, Milka
AU  - Reljin, Irini S.
AU  - Reljin, Branimir D.
AU  - Plavec, Goran I.
AU  - Petrović, Slobodan
AU  - Mijin, Dušan
PY  - 2014
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/2849
AB  - The automated, computer-aided method for differentiation and classification of malignant (M) from benign (B) cases, by analyzing the UV/VIS spectra of pleural effusions is described. It was shown that by two independent objective features, the maximum of Katz fractal dimension (KFDmax) and the area under normalized UV/VIS absorbance curve (Area), highly reliable M-B classification is possible. In the Area-KFDmax space M and B samples are linearly separable permitting thus the use of linear support vector machine as a classification tool. By analyzing 104 samples of UV/VIS spectra of pleural effusions (88 M and 16 B) collected from patients at the Clinic for Lung Diseases and Tuberculosis, Military Medical Academy in Belgrade, the accuracy of 95.45% for M cases and 100% for B cases are obtained by using the proposed method. It was shown that by applying some modifications, which are suggested in the paper, the accuracy of 100% for M cases can be reached.
PB  - Elsevier, Amsterdam
T2  - Physica A-Statistical Mechanics and Its Applications
T1  - Diagnostic spectroscopic and computer-aided evaluation of malignancy from UV/VIS spectra of clear pleural effusions
EP  - 216
SP  - 206
VL  - 403
DO  - 10.1016/j.physa.2014.02.026
ER  - 

@article{
author = "Jevtić, Dubravka R. and Avramov-Ivić, Milka and Reljin, Irini S. and Reljin, Branimir D. and Plavec, Goran I. and Petrović, Slobodan and Mijin, Dušan",
year = "2014",
abstract = "The automated, computer-aided method for differentiation and classification of malignant (M) from benign (B) cases, by analyzing the UV/VIS spectra of pleural effusions is described. It was shown that by two independent objective features, the maximum of Katz fractal dimension (KFDmax) and the area under normalized UV/VIS absorbance curve (Area), highly reliable M-B classification is possible. In the Area-KFDmax space M and B samples are linearly separable permitting thus the use of linear support vector machine as a classification tool. By analyzing 104 samples of UV/VIS spectra of pleural effusions (88 M and 16 B) collected from patients at the Clinic for Lung Diseases and Tuberculosis, Military Medical Academy in Belgrade, the accuracy of 95.45% for M cases and 100% for B cases are obtained by using the proposed method. It was shown that by applying some modifications, which are suggested in the paper, the accuracy of 100% for M cases can be reached.",
publisher = "Elsevier, Amsterdam",
journal = "Physica A-Statistical Mechanics and Its Applications",
title = "Diagnostic spectroscopic and computer-aided evaluation of malignancy from UV/VIS spectra of clear pleural effusions",
pages = "216-206",
volume = "403",
doi = "10.1016/j.physa.2014.02.026"
}

Jevtić, D. R., Avramov-Ivić, M., Reljin, I. S., Reljin, B. D., Plavec, G. I., Petrović, S.,& Mijin, D.. (2014). Diagnostic spectroscopic and computer-aided evaluation of malignancy from UV/VIS spectra of clear pleural effusions. in Physica A-Statistical Mechanics and Its Applications
Elsevier, Amsterdam., 403, 206-216.
https://doi.org/10.1016/j.physa.2014.02.026

Jevtić DR, Avramov-Ivić M, Reljin IS, Reljin BD, Plavec GI, Petrović S, Mijin D. Diagnostic spectroscopic and computer-aided evaluation of malignancy from UV/VIS spectra of clear pleural effusions. in Physica A-Statistical Mechanics and Its Applications. 2014;403:206-216.
doi:10.1016/j.physa.2014.02.026 .

Jevtić, Dubravka R., Avramov-Ivić, Milka, Reljin, Irini S., Reljin, Branimir D., Plavec, Goran I., Petrović, Slobodan, Mijin, Dušan, "Diagnostic spectroscopic and computer-aided evaluation of malignancy from UV/VIS spectra of clear pleural effusions" in Physica A-Statistical Mechanics and Its Applications, 403 (2014):206-216,
https://doi.org/10.1016/j.physa.2014.02.026 . .

TY  - JOUR
AU  - Reljin, Irini S.
AU  - Reljin, Branimir D.
AU  - Avramov-Ivić, Milka
AU  - Jovanović, D. V.
AU  - Plavec, Goran I.
AU  - Petrović, Slobodan
AU  - Bogdanović, Gordana
PY  - 2008
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/1334
AB  - Multifractal (MF) approach was applied for the analysis of ultraviolet/visible (UV/VIS) spectra as an independent confirmation of the diagnostic efficacy of UV/VIS spectral analysis of intraperitoneal fluids, ascites, taken from patients with a known clinical diagnosis. Recently, it was reported that from UV/VIS spectra differentiation of malignant from benign ascites is possible. Here, it was shown that by using MF analysis of UV/VIS spectra, the objective classification of UV/VIS spectra is possible. The applicability of UV/VIS analysis and MF classification of spectra were evaluated on N = 68 cases, of which M = 64 and B = 4 were clinically confirmed as malignant and benign, respectively. The overall diagnostic efficacy was 89.71% when using on-line analysis of UV/VIS spectra (61 out of 68 samples were positively recognized: 58 malignant and 3 benign), and even 95.59% by using off-line MF classsification (65 out of 68 samples were classified correctly: 63 malignant and 2 benign). It can be inferred that UV/VIS spectral analysis of ascites, combined with MF analysis, could be suggested as a successful and safe screening method in the evaluation of intraperitoneal fluids.
PB  - Elsevier Science Bv, Amsterdam
T2  - Physica A-Statistical Mechanics and Its Applications
T1  - Multifractal analysis of the UV/VIS spectra of malignant ascites: Confirmation of the diagnostic validity of a clinically evaluated spectral analysis
EP  - 3573
IS  - 14
SP  - 3563
VL  - 387
DO  - 10.1016/j.physa.2008.02.029
ER  - 

@article{
author = "Reljin, Irini S. and Reljin, Branimir D. and Avramov-Ivić, Milka and Jovanović, D. V. and Plavec, Goran I. and Petrović, Slobodan and Bogdanović, Gordana",
year = "2008",
abstract = "Multifractal (MF) approach was applied for the analysis of ultraviolet/visible (UV/VIS) spectra as an independent confirmation of the diagnostic efficacy of UV/VIS spectral analysis of intraperitoneal fluids, ascites, taken from patients with a known clinical diagnosis. Recently, it was reported that from UV/VIS spectra differentiation of malignant from benign ascites is possible. Here, it was shown that by using MF analysis of UV/VIS spectra, the objective classification of UV/VIS spectra is possible. The applicability of UV/VIS analysis and MF classification of spectra were evaluated on N = 68 cases, of which M = 64 and B = 4 were clinically confirmed as malignant and benign, respectively. The overall diagnostic efficacy was 89.71% when using on-line analysis of UV/VIS spectra (61 out of 68 samples were positively recognized: 58 malignant and 3 benign), and even 95.59% by using off-line MF classsification (65 out of 68 samples were classified correctly: 63 malignant and 2 benign). It can be inferred that UV/VIS spectral analysis of ascites, combined with MF analysis, could be suggested as a successful and safe screening method in the evaluation of intraperitoneal fluids.",
publisher = "Elsevier Science Bv, Amsterdam",
journal = "Physica A-Statistical Mechanics and Its Applications",
title = "Multifractal analysis of the UV/VIS spectra of malignant ascites: Confirmation of the diagnostic validity of a clinically evaluated spectral analysis",
pages = "3573-3563",
number = "14",
volume = "387",
doi = "10.1016/j.physa.2008.02.029"
}

Reljin, I. S., Reljin, B. D., Avramov-Ivić, M., Jovanović, D. V., Plavec, G. I., Petrović, S.,& Bogdanović, G.. (2008). Multifractal analysis of the UV/VIS spectra of malignant ascites: Confirmation of the diagnostic validity of a clinically evaluated spectral analysis. in Physica A-Statistical Mechanics and Its Applications
Elsevier Science Bv, Amsterdam., 387(14), 3563-3573.
https://doi.org/10.1016/j.physa.2008.02.029

Reljin IS, Reljin BD, Avramov-Ivić M, Jovanović DV, Plavec GI, Petrović S, Bogdanović G. Multifractal analysis of the UV/VIS spectra of malignant ascites: Confirmation of the diagnostic validity of a clinically evaluated spectral analysis. in Physica A-Statistical Mechanics and Its Applications. 2008;387(14):3563-3573.
doi:10.1016/j.physa.2008.02.029 .

Reljin, Irini S., Reljin, Branimir D., Avramov-Ivić, Milka, Jovanović, D. V., Plavec, Goran I., Petrović, Slobodan, Bogdanović, Gordana, "Multifractal analysis of the UV/VIS spectra of malignant ascites: Confirmation of the diagnostic validity of a clinically evaluated spectral analysis" in Physica A-Statistical Mechanics and Its Applications, 387, no. 14 (2008):3563-3573,
https://doi.org/10.1016/j.physa.2008.02.029 . .