@conference{
author = "Nowak, Mariusz and Semba, Damian and Mišić, Dušan and Półbrat, Tomasz and Stojanović, Dušica and Trusek, Anna and Žižović, Irena",
year = "2022",
abstract = "There is an urgency to develop novel materials capable of preventing the adherence of microorganisms to
their surface. Such materials with antibiofilm properties are needed in hospitals and public places, animal
farms and veterinary hospitals, and biofouling prevention. Biofouling is the phenomenon of adhesion and
the growth of microorganisms on surfaces in contact with water. It poses a significant problem for filtration
processes, water treatment units, bioreactors, and ships performance (marine biofouling). High-pressure
techniques such as supercritical solvent impregnation and grafting in the supercritical phase allow for the
modification of a solid matrix throughout the whole volume and production of materials of unique
properties in an environmentally friendly way. Grafting involves the chemical attachment of an active
compound to a solid matrix, ensuring its long-lasting properties. Grafting in supercritical carbon dioxide
(scCO2) has been reported as an efficient tool in the production of materials with antibacterial1
, and recently
also antibiofilm properties2
. This study aims to investigate the potential of cellulose acetate (CA) grafting
with quaternary ammonium compounds (QAC) for acquiring antibiofilm properties. Two QAC were
synthesized, and the grafting conditions were investigated. The grafting was performed via hexamethylene
diisocyanate (HDI) as a linker1
. Obtained materials were analyzed using FTIR, SEM and Ion microscopy,
DSC analyses, contact angle measurements, and standardized microbiological procedures to evaluate
antibiofilm properties.",
journal = "13th International Symposium on Supercritical Fluids Montreal, ISSF2022, Canada, May 15-18, 2022",
title = "Cellulose Acetate Modification Towards Antibiofilm Properties via Chemical Attachment of Quaternary Ammonium Compounds using Supercritical CO2",
url = "https://hdl.handle.net/21.15107/rcub_technorep_6937"
}