TY  - JOUR
AU  - Popović, Marko E.
AU  - Stevanović, Maja
AU  - Mihailović, Marija
PY  - 2024
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/7433
AB  - Breaking news are usually disturbing. Natural disasters, wars, epidemics, etc., are reported as breaking news. This paper reports a decreased danger of spreading of epidemics caused by the JN.1 variant, since analyses indicate that infectivity of the new variant is decreased compared to most earlier variants, which is confirmed by the number of cases (7500 daily in USA). Moreover, JN.1, despite the great number of mutations, has not been able to achieve the values of Gibbs energy change of biosynthesis (and thus virus multiplication rate) of the Hu-1 wild type. The research shows that infectivity and pathogenicity of the JN.1 variant has not reached worrying size, which means that there is no reason to expect the epidemiologic situation getting worse.
AB  - Ударне вести су обично узнемирујуће. О природним катастрофама, ратовима, епидемијама, итд. се извештава као о ударним вестима. У овом раду је приказано смањење опасности од ширења епидемија изазваних варијантом JN.1, јер анализе показују да је инфективност нове варијанте слабија у односу на већину ранијих варијанти, што потврђује и број случајева (7500 дневно у САД). Штавише, JN.1 упркос великом броју мутација није успео да постигне вредности промене Гибсове енергије биосинтезе (а самим тим и стопе размножавања вируса) дивљег типа Hu.1. Истраживање показује да инфективност и патогеност варијанте JN.1 није достигла забрињавајућу величину, што значи да нема разлога за очекивање погоршање епидемиолошке ситуације.
PB  - Serbian Chemical Society
T2  - Journal of the Serbian Chemical Society
T1  - Breaking news: Empirical formulas, molar masses, biosynthesis reactions and thermodynamic properties of virus particles - Biosynthesis and binding of Omicron JN.1 variant of SARS-CoV-2
T1  - Ударне вести: емпиријске формуле, моларне масе, реакције биосинтезе и термодинамичке особине вирусних честица: биосинтезе и везивања Omicron JN.1 варијанте SARS-CoV-2
EP  - 320
IS  - 3
SP  - 305
VL  - 89
DO  - 10.2298/JSC240119019P
ER  - 

@article{
author = "Popović, Marko E. and Stevanović, Maja and Mihailović, Marija",
year = "2024",
abstract = "Breaking news are usually disturbing. Natural disasters, wars, epidemics, etc., are reported as breaking news. This paper reports a decreased danger of spreading of epidemics caused by the JN.1 variant, since analyses indicate that infectivity of the new variant is decreased compared to most earlier variants, which is confirmed by the number of cases (7500 daily in USA). Moreover, JN.1, despite the great number of mutations, has not been able to achieve the values of Gibbs energy change of biosynthesis (and thus virus multiplication rate) of the Hu-1 wild type. The research shows that infectivity and pathogenicity of the JN.1 variant has not reached worrying size, which means that there is no reason to expect the epidemiologic situation getting worse., Ударне вести су обично узнемирујуће. О природним катастрофама, ратовима, епидемијама, итд. се извештава као о ударним вестима. У овом раду је приказано смањење опасности од ширења епидемија изазваних варијантом JN.1, јер анализе показују да је инфективност нове варијанте слабија у односу на већину ранијих варијанти, што потврђује и број случајева (7500 дневно у САД). Штавише, JN.1 упркос великом броју мутација није успео да постигне вредности промене Гибсове енергије биосинтезе (а самим тим и стопе размножавања вируса) дивљег типа Hu.1. Истраживање показује да инфективност и патогеност варијанте JN.1 није достигла забрињавајућу величину, што значи да нема разлога за очекивање погоршање епидемиолошке ситуације.",
publisher = "Serbian Chemical Society",
journal = "Journal of the Serbian Chemical Society",
title = "Breaking news: Empirical formulas, molar masses, biosynthesis reactions and thermodynamic properties of virus particles - Biosynthesis and binding of Omicron JN.1 variant of SARS-CoV-2, Ударне вести: емпиријске формуле, моларне масе, реакције биосинтезе и термодинамичке особине вирусних честица: биосинтезе и везивања Omicron JN.1 варијанте SARS-CoV-2",
pages = "320-305",
number = "3",
volume = "89",
doi = "10.2298/JSC240119019P"
}

Popović, M. E., Stevanović, M.,& Mihailović, M.. (2024). Breaking news: Empirical formulas, molar masses, biosynthesis reactions and thermodynamic properties of virus particles - Biosynthesis and binding of Omicron JN.1 variant of SARS-CoV-2. in Journal of the Serbian Chemical Society
Serbian Chemical Society., 89(3), 305-320.
https://doi.org/10.2298/JSC240119019P

Popović ME, Stevanović M, Mihailović M. Breaking news: Empirical formulas, molar masses, biosynthesis reactions and thermodynamic properties of virus particles - Biosynthesis and binding of Omicron JN.1 variant of SARS-CoV-2. in Journal of the Serbian Chemical Society. 2024;89(3):305-320.
doi:10.2298/JSC240119019P .

Popović, Marko E., Stevanović, Maja, Mihailović, Marija, "Breaking news: Empirical formulas, molar masses, biosynthesis reactions and thermodynamic properties of virus particles - Biosynthesis and binding of Omicron JN.1 variant of SARS-CoV-2" in Journal of the Serbian Chemical Society, 89, no. 3 (2024):305-320,
https://doi.org/10.2298/JSC240119019P . .

TY  - JOUR
AU  - Popović, Marko E.
AU  - Stevanović, Maja
AU  - Pantović Pavlović, Marijana
PY  - 2024
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/7432
AB  - Pertussis (whooping cough) has been nearly eradicated during the 20th century, first of all due to an organized and comprehensive vaccination campaign that lasted for decades. Generations of doctors educated in Serbia (and other countries) rarely had an opportunity to see the clinical picture of pertussis. However, during 2023, the number of registered cases of pertussis in Serbia has increased several times. This is why the health authorities were forced to declare danger of an epidemic. During 2023, in Belgrade, around 1000 cases were registered. During the two months of 2024, 400 cases were registered. Some of them have ended with lethal outcome. This paper reports for the first time the biosynthesis reaction and thermodynamic properties of biosynthesis (enthalpy, entropy and Gibbs energy) of Bordetella pertussis, the cause of whooping cough. Moreover, a mechanistic model of multiplication of B. pertussis was developed. The mechanistic model was related to the pathogenesis of pertussis.
PB  - Elsevier B.V.
T2  - Microbial Risk Analysis
T1  - Return of the forgotten nightmare: Bordetella pertussis uses a more negative Gibbs energy of metabolism to outcompete its host organism
SP  - 100292
VL  - 26
DO  - 10.1016/j.mran.2024.100292
ER  - 

@article{
author = "Popović, Marko E. and Stevanović, Maja and Pantović Pavlović, Marijana",
year = "2024",
abstract = "Pertussis (whooping cough) has been nearly eradicated during the 20th century, first of all due to an organized and comprehensive vaccination campaign that lasted for decades. Generations of doctors educated in Serbia (and other countries) rarely had an opportunity to see the clinical picture of pertussis. However, during 2023, the number of registered cases of pertussis in Serbia has increased several times. This is why the health authorities were forced to declare danger of an epidemic. During 2023, in Belgrade, around 1000 cases were registered. During the two months of 2024, 400 cases were registered. Some of them have ended with lethal outcome. This paper reports for the first time the biosynthesis reaction and thermodynamic properties of biosynthesis (enthalpy, entropy and Gibbs energy) of Bordetella pertussis, the cause of whooping cough. Moreover, a mechanistic model of multiplication of B. pertussis was developed. The mechanistic model was related to the pathogenesis of pertussis.",
publisher = "Elsevier B.V.",
journal = "Microbial Risk Analysis",
title = "Return of the forgotten nightmare: Bordetella pertussis uses a more negative Gibbs energy of metabolism to outcompete its host organism",
pages = "100292",
volume = "26",
doi = "10.1016/j.mran.2024.100292"
}

Popović, M. E., Stevanović, M.,& Pantović Pavlović, M.. (2024). Return of the forgotten nightmare: Bordetella pertussis uses a more negative Gibbs energy of metabolism to outcompete its host organism. in Microbial Risk Analysis
Elsevier B.V.., 26, 100292.
https://doi.org/10.1016/j.mran.2024.100292

Popović ME, Stevanović M, Pantović Pavlović M. Return of the forgotten nightmare: Bordetella pertussis uses a more negative Gibbs energy of metabolism to outcompete its host organism. in Microbial Risk Analysis. 2024;26:100292.
doi:10.1016/j.mran.2024.100292 .

Popović, Marko E., Stevanović, Maja, Pantović Pavlović, Marijana, "Return of the forgotten nightmare: Bordetella pertussis uses a more negative Gibbs energy of metabolism to outcompete its host organism" in Microbial Risk Analysis, 26 (2024):100292,
https://doi.org/10.1016/j.mran.2024.100292 . .