Đorđević, Aleksandar

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  • Đorđević, Aleksandar (4)
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Author's Bibliography

POLLUTION INDICES OF TRACE ELEMENTS IN SOILS OF PČINJA AND JABLANICA DISTRICTS

Miletić, Andrijana; Lučić, Milica; Đorđević, Aleksandar; Onjia, Antonije

(Serbian Society of Soil Science, 2021)

TY  - CONF
AU  - Miletić, Andrijana
AU  - Lučić, Milica
AU  - Đorđević, Aleksandar
AU  - Onjia, Antonije
PY  - 2021
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/6316
AB  - Soil samples collected from two districts of southern Serbia, Pčinja and Jablanica, were
analyzed in order to determine the content of eleven heavy metals and metalloids (As, B,
Cd, Cr, Cu, Hg, Mn, Mo, Ni, Pb, Zn). The concentration of the elements was measured by
atomic absorption spectrometry in 152 samples collected from agricultural land. The main
goal was to assess the environmental and health risk of eleven heavy metals and metalloids
tested in the soil. To determine the degree of soil contamination, measured concentrations
were compared with limits and remediation values given in the Serbian Rulebook. It was
determined that the average content of tested elements in mg/kg was: As (12.76), B
(113.73), Cd (1.10), Cr (58.01), Cu (29.62), Hg (0.33), Mn (1067.89), Mo (0.21), Ni
(34.85), Pb (233.38), Zn (64.49). The average content of all examined trace elements in
soil did not exceed the remediation values. However, the average content of Cd, Hg, Pb
exceeded the limit values. Five pollution indices were used to assess environmental risk:
enrichment factor (EF), geoaccumulation index (Igeo), contamination factor (CF),
pollution load index (PLI), and potential environmental risk index (RI). Based on EF and
Igeo, it was concluded that the biggest problem was As, Hg and Pb. More than half of the
samples are moderately contaminated with Pb, over 30% of samples are heavily
contaminated with Hg, while some samples were highly polluted with As. Contamination
factor, as well as PLI and RI, showed moderate contamination of the soil with Hg and Cd.
The health risk assessment was estimated by hazard index (HI) and the carcinogenic risk
index (CR), which determine the non-carcinogenic and carcinogenic effects that heavy
metals can cause in the human body, throught ingestion, inhalation and dermal contact
with contaminated soil. This study showed that there was no non-carcinogenic risk as
adults-hazard index (HI) calculated for each sample was less than one. On the other hand,
there was a higher risk for children's health since over 85% of soil samples had HI values
greater than one. Combine carcinogenic risk of all elements was estimated with lifetime
carcinogenic risk (LCR). There is no risk of developing cancer in both groups because
more than 90% of the samples had acceptable carcinogenic risk values between 1,0*10-6
i 1,0*10-4, while a small number had concern LCR values grater than 1,0*10-4.
PB  - Serbian Society of Soil Science
C3  - Soils for Future under Global Challenges, BOOK OF ABSTRACTS
T1  - POLLUTION INDICES OF TRACE ELEMENTS IN SOILS OF PČINJA AND JABLANICA DISTRICTS
SP  - 91
UR  - https://hdl.handle.net/21.15107/rcub_technorep_6316
ER  - 
@conference{
author = "Miletić, Andrijana and Lučić, Milica and Đorđević, Aleksandar and Onjia, Antonije",
year = "2021",
abstract = "Soil samples collected from two districts of southern Serbia, Pčinja and Jablanica, were
analyzed in order to determine the content of eleven heavy metals and metalloids (As, B,
Cd, Cr, Cu, Hg, Mn, Mo, Ni, Pb, Zn). The concentration of the elements was measured by
atomic absorption spectrometry in 152 samples collected from agricultural land. The main
goal was to assess the environmental and health risk of eleven heavy metals and metalloids
tested in the soil. To determine the degree of soil contamination, measured concentrations
were compared with limits and remediation values given in the Serbian Rulebook. It was
determined that the average content of tested elements in mg/kg was: As (12.76), B
(113.73), Cd (1.10), Cr (58.01), Cu (29.62), Hg (0.33), Mn (1067.89), Mo (0.21), Ni
(34.85), Pb (233.38), Zn (64.49). The average content of all examined trace elements in
soil did not exceed the remediation values. However, the average content of Cd, Hg, Pb
exceeded the limit values. Five pollution indices were used to assess environmental risk:
enrichment factor (EF), geoaccumulation index (Igeo), contamination factor (CF),
pollution load index (PLI), and potential environmental risk index (RI). Based on EF and
Igeo, it was concluded that the biggest problem was As, Hg and Pb. More than half of the
samples are moderately contaminated with Pb, over 30% of samples are heavily
contaminated with Hg, while some samples were highly polluted with As. Contamination
factor, as well as PLI and RI, showed moderate contamination of the soil with Hg and Cd.
The health risk assessment was estimated by hazard index (HI) and the carcinogenic risk
index (CR), which determine the non-carcinogenic and carcinogenic effects that heavy
metals can cause in the human body, throught ingestion, inhalation and dermal contact
with contaminated soil. This study showed that there was no non-carcinogenic risk as
adults-hazard index (HI) calculated for each sample was less than one. On the other hand,
there was a higher risk for children's health since over 85% of soil samples had HI values
greater than one. Combine carcinogenic risk of all elements was estimated with lifetime
carcinogenic risk (LCR). There is no risk of developing cancer in both groups because
more than 90% of the samples had acceptable carcinogenic risk values between 1,0*10-6
i 1,0*10-4, while a small number had concern LCR values grater than 1,0*10-4.",
publisher = "Serbian Society of Soil Science",
journal = "Soils for Future under Global Challenges, BOOK OF ABSTRACTS",
title = "POLLUTION INDICES OF TRACE ELEMENTS IN SOILS OF PČINJA AND JABLANICA DISTRICTS",
pages = "91",
url = "https://hdl.handle.net/21.15107/rcub_technorep_6316"
}
Miletić, A., Lučić, M., Đorđević, A.,& Onjia, A.. (2021). POLLUTION INDICES OF TRACE ELEMENTS IN SOILS OF PČINJA AND JABLANICA DISTRICTS. in Soils for Future under Global Challenges, BOOK OF ABSTRACTS
Serbian Society of Soil Science., 91.
https://hdl.handle.net/21.15107/rcub_technorep_6316
Miletić A, Lučić M, Đorđević A, Onjia A. POLLUTION INDICES OF TRACE ELEMENTS IN SOILS OF PČINJA AND JABLANICA DISTRICTS. in Soils for Future under Global Challenges, BOOK OF ABSTRACTS. 2021;:91.
https://hdl.handle.net/21.15107/rcub_technorep_6316 .
Miletić, Andrijana, Lučić, Milica, Đorđević, Aleksandar, Onjia, Antonije, "POLLUTION INDICES OF TRACE ELEMENTS IN SOILS OF PČINJA AND JABLANICA DISTRICTS" in Soils for Future under Global Challenges, BOOK OF ABSTRACTS (2021):91,
https://hdl.handle.net/21.15107/rcub_technorep_6316 .

Geospatial mapping of health risk from trace metal(loid)s in the soil at an abandoned painting factory

Miletić, Andrijana; Savić, Aleksandra; Slavković-Beškoski, Latinka; Đorđević, Aleksandar; Dragovic, Snezana; Dragovic, Ranko; Onjia, Antonije

(University of Niš, Faculty of Sciences and Mathematics, 2020)

TY  - JOUR
AU  - Miletić, Andrijana
AU  - Savić, Aleksandra
AU  - Slavković-Beškoski, Latinka
AU  - Đorđević, Aleksandar
AU  - Dragovic, Snezana
AU  - Dragovic, Ranko
AU  - Onjia, Antonije
PY  - 2020
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/6319
AB  - A survey was made to analyze the geostatistical (GIS) distribution of the health risk of toxic
trace metal(loid)s in the industrial soil located in the facility of an abandoned paints manufacturing company. A total of eighty surface soil samples were collected, and their concentrations determined. The mean concentration values of the elements were 7.8; 2.7; 55; 49;
0.21; 56; 114; and 239 mg/kg for As, Cd, Cr, Cu, Hg, Ni, Pb, and Zn, respectively. There was
no non-carcinogenic health risk from the soil samples for adults, but it was hazardous soil
for children with the excess lifetime cancer risk (ELCR) values exceeding the reference value
of 10-4 for all studied samples. Most contributing toxic metal(loid)s to non-carcinogenic risk
were Cr and As, whereas Pb and As were most responsible for cancer risk. Geospatial mapping of the hazard index (HI) and ELCR localized different hotspots seriously polluted by
toxic metal(loid)s, which pose a significant risk in the area. These hotspots coincided with
the evidence of transport-related activities and spillage of chemicals in the past. This GIS
spatial distribution study could be a valuable aid in remediation planning.
PB  - University of Niš, Faculty of Sciences and Mathematics
T2  - Serbian Journal of Geosciences
T1  - Geospatial mapping of health risk from trace metal(loid)s in the soil at an abandoned painting factory
EP  - 7
IS  - 1
SP  - 1
VL  - 6
DO  - 10.18485/srbjgeosci.2020.6.1.1
ER  - 
@article{
author = "Miletić, Andrijana and Savić, Aleksandra and Slavković-Beškoski, Latinka and Đorđević, Aleksandar and Dragovic, Snezana and Dragovic, Ranko and Onjia, Antonije",
year = "2020",
abstract = "A survey was made to analyze the geostatistical (GIS) distribution of the health risk of toxic
trace metal(loid)s in the industrial soil located in the facility of an abandoned paints manufacturing company. A total of eighty surface soil samples were collected, and their concentrations determined. The mean concentration values of the elements were 7.8; 2.7; 55; 49;
0.21; 56; 114; and 239 mg/kg for As, Cd, Cr, Cu, Hg, Ni, Pb, and Zn, respectively. There was
no non-carcinogenic health risk from the soil samples for adults, but it was hazardous soil
for children with the excess lifetime cancer risk (ELCR) values exceeding the reference value
of 10-4 for all studied samples. Most contributing toxic metal(loid)s to non-carcinogenic risk
were Cr and As, whereas Pb and As were most responsible for cancer risk. Geospatial mapping of the hazard index (HI) and ELCR localized different hotspots seriously polluted by
toxic metal(loid)s, which pose a significant risk in the area. These hotspots coincided with
the evidence of transport-related activities and spillage of chemicals in the past. This GIS
spatial distribution study could be a valuable aid in remediation planning.",
publisher = "University of Niš, Faculty of Sciences and Mathematics",
journal = "Serbian Journal of Geosciences",
title = "Geospatial mapping of health risk from trace metal(loid)s in the soil at an abandoned painting factory",
pages = "7-1",
number = "1",
volume = "6",
doi = "10.18485/srbjgeosci.2020.6.1.1"
}
Miletić, A., Savić, A., Slavković-Beškoski, L., Đorđević, A., Dragovic, S., Dragovic, R.,& Onjia, A.. (2020). Geospatial mapping of health risk from trace metal(loid)s in the soil at an abandoned painting factory. in Serbian Journal of Geosciences
University of Niš, Faculty of Sciences and Mathematics., 6(1), 1-7.
https://doi.org/10.18485/srbjgeosci.2020.6.1.1
Miletić A, Savić A, Slavković-Beškoski L, Đorđević A, Dragovic S, Dragovic R, Onjia A. Geospatial mapping of health risk from trace metal(loid)s in the soil at an abandoned painting factory. in Serbian Journal of Geosciences. 2020;6(1):1-7.
doi:10.18485/srbjgeosci.2020.6.1.1 .
Miletić, Andrijana, Savić, Aleksandra, Slavković-Beškoski, Latinka, Đorđević, Aleksandar, Dragovic, Snezana, Dragovic, Ranko, Onjia, Antonije, "Geospatial mapping of health risk from trace metal(loid)s in the soil at an abandoned painting factory" in Serbian Journal of Geosciences, 6, no. 1 (2020):1-7,
https://doi.org/10.18485/srbjgeosci.2020.6.1.1 . .
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Hydroxylated fullerene-capped, vinblastine-loaded folic acid-functionalized mesoporous silica nanoparticles for targeted anticancer therapy

Knežević, Nikola Ž.; Mrdanović, Jasminka; Borisev, Ivana; Milenković, Sanja; Janaćković, Đorđe; Cunin, Frederique; Đorđević, Aleksandar

(Royal Society of Chemistry, 2016)

TY  - JOUR
AU  - Knežević, Nikola Ž.
AU  - Mrdanović, Jasminka
AU  - Borisev, Ivana
AU  - Milenković, Sanja
AU  - Janaćković, Đorđe
AU  - Cunin, Frederique
AU  - Đorđević, Aleksandar
PY  - 2016
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3386
AB  - A novel cancer-targeting drug delivery system is constructed and characterized, based on folic acid-functionalized mesoporous silica nanoparticles with pore-loaded anticancer drug vinblastine and pore-blocking fullerenol molecules. The selective treatment efficacy based on targeting of cancer-verexpressed folate receptors is demonstrated by comparison of cell viability upon the treatment of healthy MRC-5, breast cancer MCF-7 and cervical cancer HeLa cells, which are known to differ in the amount of folate receptors on their surfaces.
PB  - Royal Society of Chemistry
T2  - RSC Advances
T1  - Hydroxylated fullerene-capped, vinblastine-loaded folic acid-functionalized mesoporous silica nanoparticles for targeted anticancer therapy
EP  - 7065
IS  - 9
SP  - 7061
VL  - 6
DO  - 10.1039/c5ra22937e
ER  - 
@article{
author = "Knežević, Nikola Ž. and Mrdanović, Jasminka and Borisev, Ivana and Milenković, Sanja and Janaćković, Đorđe and Cunin, Frederique and Đorđević, Aleksandar",
year = "2016",
abstract = "A novel cancer-targeting drug delivery system is constructed and characterized, based on folic acid-functionalized mesoporous silica nanoparticles with pore-loaded anticancer drug vinblastine and pore-blocking fullerenol molecules. The selective treatment efficacy based on targeting of cancer-verexpressed folate receptors is demonstrated by comparison of cell viability upon the treatment of healthy MRC-5, breast cancer MCF-7 and cervical cancer HeLa cells, which are known to differ in the amount of folate receptors on their surfaces.",
publisher = "Royal Society of Chemistry",
journal = "RSC Advances",
title = "Hydroxylated fullerene-capped, vinblastine-loaded folic acid-functionalized mesoporous silica nanoparticles for targeted anticancer therapy",
pages = "7065-7061",
number = "9",
volume = "6",
doi = "10.1039/c5ra22937e"
}
Knežević, N. Ž., Mrdanović, J., Borisev, I., Milenković, S., Janaćković, Đ., Cunin, F.,& Đorđević, A.. (2016). Hydroxylated fullerene-capped, vinblastine-loaded folic acid-functionalized mesoporous silica nanoparticles for targeted anticancer therapy. in RSC Advances
Royal Society of Chemistry., 6(9), 7061-7065.
https://doi.org/10.1039/c5ra22937e
Knežević NŽ, Mrdanović J, Borisev I, Milenković S, Janaćković Đ, Cunin F, Đorđević A. Hydroxylated fullerene-capped, vinblastine-loaded folic acid-functionalized mesoporous silica nanoparticles for targeted anticancer therapy. in RSC Advances. 2016;6(9):7061-7065.
doi:10.1039/c5ra22937e .
Knežević, Nikola Ž., Mrdanović, Jasminka, Borisev, Ivana, Milenković, Sanja, Janaćković, Đorđe, Cunin, Frederique, Đorđević, Aleksandar, "Hydroxylated fullerene-capped, vinblastine-loaded folic acid-functionalized mesoporous silica nanoparticles for targeted anticancer therapy" in RSC Advances, 6, no. 9 (2016):7061-7065,
https://doi.org/10.1039/c5ra22937e . .
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Fullerenol-Capped Porous Silica Nanoparticles for pH-Responsive Drug Delivery

Knežević, Nikola Ž.; Milenković, Sanja; Jović, Danica; Lazarević, Slavica; Mrđanović, Jasminka; Đorđević, Aleksandar

(Hindawi Ltd, London, 2015)

TY  - JOUR
AU  - Knežević, Nikola Ž.
AU  - Milenković, Sanja
AU  - Jović, Danica
AU  - Lazarević, Slavica
AU  - Mrđanović, Jasminka
AU  - Đorđević, Aleksandar
PY  - 2015
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3130
AB  - Novel nanocomposite containing fullerenol nanoparticles (FNP) and porous silica nanoparticles (PSNs) was constructed and characterized. The capability of FNP to serve as a pore-capping agent and for entrapping 9-aminoacridine (9-AA) inside the pores of the PSN material was also demonstrated. Nitrogen sorption measurements evidence the successful capping of the silica pores while thermogravimetric analysis of FNP loaded PSN indicates the existence of pore-loaded fullerenol molecules. Higher amount of the drug release was noted by exposing the material to weakly acidic conditions in comparison to physiological pH, which may find application in targeted treatment of weakly acidic tumor tissues.
PB  - Hindawi Ltd, London
T2  - Advances in Materials Science and Engineering
T1  - Fullerenol-Capped Porous Silica Nanoparticles for pH-Responsive Drug Delivery
VL  - 2015
DO  - 10.1155/2015/567350
ER  - 
@article{
author = "Knežević, Nikola Ž. and Milenković, Sanja and Jović, Danica and Lazarević, Slavica and Mrđanović, Jasminka and Đorđević, Aleksandar",
year = "2015",
abstract = "Novel nanocomposite containing fullerenol nanoparticles (FNP) and porous silica nanoparticles (PSNs) was constructed and characterized. The capability of FNP to serve as a pore-capping agent and for entrapping 9-aminoacridine (9-AA) inside the pores of the PSN material was also demonstrated. Nitrogen sorption measurements evidence the successful capping of the silica pores while thermogravimetric analysis of FNP loaded PSN indicates the existence of pore-loaded fullerenol molecules. Higher amount of the drug release was noted by exposing the material to weakly acidic conditions in comparison to physiological pH, which may find application in targeted treatment of weakly acidic tumor tissues.",
publisher = "Hindawi Ltd, London",
journal = "Advances in Materials Science and Engineering",
title = "Fullerenol-Capped Porous Silica Nanoparticles for pH-Responsive Drug Delivery",
volume = "2015",
doi = "10.1155/2015/567350"
}
Knežević, N. Ž., Milenković, S., Jović, D., Lazarević, S., Mrđanović, J.,& Đorđević, A.. (2015). Fullerenol-Capped Porous Silica Nanoparticles for pH-Responsive Drug Delivery. in Advances in Materials Science and Engineering
Hindawi Ltd, London., 2015.
https://doi.org/10.1155/2015/567350
Knežević NŽ, Milenković S, Jović D, Lazarević S, Mrđanović J, Đorđević A. Fullerenol-Capped Porous Silica Nanoparticles for pH-Responsive Drug Delivery. in Advances in Materials Science and Engineering. 2015;2015.
doi:10.1155/2015/567350 .
Knežević, Nikola Ž., Milenković, Sanja, Jović, Danica, Lazarević, Slavica, Mrđanović, Jasminka, Đorđević, Aleksandar, "Fullerenol-Capped Porous Silica Nanoparticles for pH-Responsive Drug Delivery" in Advances in Materials Science and Engineering, 2015 (2015),
https://doi.org/10.1155/2015/567350 . .
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