Marković, Tatjana

Link to this page

Authority KeyName Variants
ab38228b-043c-4bfe-8c3b-78b9b33124be
  • Marković, Tatjana (6)
Projects
Ministry of Education, Science and Technological Development, Republic of Serbia, Grant no. 451-03-68/2020-14/200019 (University of Belgrade, Institute for the Application of Nuclear Energy - INEP) Ministry of Education, Science and Technological Development, Republic of Serbia, Grant no. 451-03-68/2020-14/200003 (Institute for Medicinal Plant Research 'Dr. Josif Pančić ', Belgrade)
Razvoj tehnologije gajenja kukuruza sa ekološkim pristupom Application of nanomaterials in the improvement of respiratory and percutaneous protective equipment in ecological disbalance conditions caused by radioactive chemical and biological contamination
Ministry of Education, Science and Technological Development, Republic of Serbia, Grant no. 451-03-68/2020-14/200007 (University of Belgrade, Institute for Biological Research 'Siniša Stanković') Ministry of Education, Science and Technological Development, Republic of Serbia, Grant no. 451-03-68/2020-14/200116 (University of Belgrade, Faculty of Agriculture)
Ministry of Education, Science and Technological Development, Republic of Serbia, Grant no. 451-03-68/2020-14/200135 (University of Belgrade, Faculty of Technology and Metallurgy) Ministry of Education, Science and Technological Development, Republic of Serbia, Grant no. 451-03-68/2020-14/200168 (University of Belgrade, Faculty of Chemistry)
Ministry of Education, Science and Technological Development, Republic of Serbia, Grant no. 451-03-68/2020-14/200287 (Innovation Center of the Faculty of Technology and Metallurgy) FUNPRO - Functional products based on goat's milk proteins and bioactive compounds extracted from grape pomace and edible mushrooms
MultiPromis - Multifunctional leaf protein and assembled nanocarrier structures delivered by enzyme technology Ministry of Science and Technology of the Republic of Serbia (451-03-1202/2021-09/3)
Ministry of Science, Technological Development, and Innovation of the Republic of Serbia (#Grant Nos: 451-03-1202/2021-09/3) National Key R & D Program of China (2021YFE0110700)

Author's Bibliography

Phytochemical Analysis, Biological Activities, and Molecular Docking Studies of Root Extracts from Paeonia Species in Serbia

Batinić, Petar; Jovanović, Aleksandra; Stojković, Dejan; Zengin, Gökhan; Cvijetić, Ilija; Gašić, Uroš; Čutović, Natalija; Pešić, Mirjana B.; Milinčić, Danijel D.; Carević, Tamara; Marinković, Aleksandar; Bugarski, Branko; Marković, Tatjana

(MDPI, 2024)

TY  - JOUR
AU  - Batinić, Petar
AU  - Jovanović, Aleksandra
AU  - Stojković, Dejan
AU  - Zengin, Gökhan
AU  - Cvijetić, Ilija
AU  - Gašić, Uroš
AU  - Čutović, Natalija
AU  - Pešić, Mirjana B.
AU  - Milinčić, Danijel D.
AU  - Carević, Tamara
AU  - Marinković, Aleksandar
AU  - Bugarski, Branko
AU  - Marković, Tatjana
PY  - 2024
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/7457
AB  - Without being aware of their chemical composition, many cultures have used herbaceous peony roots for medicinal purposes. Modern phytopreparations intended for use in human therapy require specific knowledge about the chemistry of peony roots and their biological activities. In this study, ethanol–water extracts were prepared by maceration and microwave- and ultrasound-assisted extractions (MAE and UAE, respectively) in order to obtain bioactive molecules from the roots of Paeonia tenuifolia L., Paeonia peregrina Mill., and Paeonia officinalis L. wild growing in Serbia. Chemical characterization; polyphenol and flavonoid content; antioxidant, multianti-enzymatic, and antibacterial activities of extracts; and in vitro gastrointestinal digestion (GID) of hot water extracts were performed. The strongest anti-cholinesterase activity was observed in PT extracts. The highest anti-ABTS (2,2′-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) radical potential was observed in PP extracts, whereas against DPPH (2,2-diphenyl-1-picrylhydrazyl radicals), the best results were achieved with PO extracts. Regarding antibacterial activity, extracts were strongly potent against Bacillus cereus. A molecular docking simulation was conducted to gather insights into the binding affinity and interactions of polyphenols and other Paeonia-specific molecules in the active sites of tested enzymes. In vitro GID of Paeonia teas showed a different recovery and behavior of the individual bioactives, with an increased recovery of methyl gallate and digallate and a decreased recovery of paeoniflorin and its derivatives. PT (Gulenovci) and PP (Pirot) extracts obtained by UAE and M were more efficient in the majority of the bioactivity assays. This study represents an initial step toward the possible application of Paeonia root extracts in pharmacy, medicine, and food technologies.
PB  - MDPI
T2  - Pharmaceuticals
T1  - Phytochemical Analysis, Biological Activities, and Molecular Docking Studies of Root Extracts from Paeonia Species in Serbia
IS  - 4
SP  - 518
VL  - 17
DO  - 10.3390/ph17040518
ER  - 
@article{
author = "Batinić, Petar and Jovanović, Aleksandra and Stojković, Dejan and Zengin, Gökhan and Cvijetić, Ilija and Gašić, Uroš and Čutović, Natalija and Pešić, Mirjana B. and Milinčić, Danijel D. and Carević, Tamara and Marinković, Aleksandar and Bugarski, Branko and Marković, Tatjana",
year = "2024",
abstract = "Without being aware of their chemical composition, many cultures have used herbaceous peony roots for medicinal purposes. Modern phytopreparations intended for use in human therapy require specific knowledge about the chemistry of peony roots and their biological activities. In this study, ethanol–water extracts were prepared by maceration and microwave- and ultrasound-assisted extractions (MAE and UAE, respectively) in order to obtain bioactive molecules from the roots of Paeonia tenuifolia L., Paeonia peregrina Mill., and Paeonia officinalis L. wild growing in Serbia. Chemical characterization; polyphenol and flavonoid content; antioxidant, multianti-enzymatic, and antibacterial activities of extracts; and in vitro gastrointestinal digestion (GID) of hot water extracts were performed. The strongest anti-cholinesterase activity was observed in PT extracts. The highest anti-ABTS (2,2′-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) radical potential was observed in PP extracts, whereas against DPPH (2,2-diphenyl-1-picrylhydrazyl radicals), the best results were achieved with PO extracts. Regarding antibacterial activity, extracts were strongly potent against Bacillus cereus. A molecular docking simulation was conducted to gather insights into the binding affinity and interactions of polyphenols and other Paeonia-specific molecules in the active sites of tested enzymes. In vitro GID of Paeonia teas showed a different recovery and behavior of the individual bioactives, with an increased recovery of methyl gallate and digallate and a decreased recovery of paeoniflorin and its derivatives. PT (Gulenovci) and PP (Pirot) extracts obtained by UAE and M were more efficient in the majority of the bioactivity assays. This study represents an initial step toward the possible application of Paeonia root extracts in pharmacy, medicine, and food technologies.",
publisher = "MDPI",
journal = "Pharmaceuticals",
title = "Phytochemical Analysis, Biological Activities, and Molecular Docking Studies of Root Extracts from Paeonia Species in Serbia",
number = "4",
pages = "518",
volume = "17",
doi = "10.3390/ph17040518"
}
Batinić, P., Jovanović, A., Stojković, D., Zengin, G., Cvijetić, I., Gašić, U., Čutović, N., Pešić, M. B., Milinčić, D. D., Carević, T., Marinković, A., Bugarski, B.,& Marković, T.. (2024). Phytochemical Analysis, Biological Activities, and Molecular Docking Studies of Root Extracts from Paeonia Species in Serbia. in Pharmaceuticals
MDPI., 17(4), 518.
https://doi.org/10.3390/ph17040518
Batinić P, Jovanović A, Stojković D, Zengin G, Cvijetić I, Gašić U, Čutović N, Pešić MB, Milinčić DD, Carević T, Marinković A, Bugarski B, Marković T. Phytochemical Analysis, Biological Activities, and Molecular Docking Studies of Root Extracts from Paeonia Species in Serbia. in Pharmaceuticals. 2024;17(4):518.
doi:10.3390/ph17040518 .
Batinić, Petar, Jovanović, Aleksandra, Stojković, Dejan, Zengin, Gökhan, Cvijetić, Ilija, Gašić, Uroš, Čutović, Natalija, Pešić, Mirjana B., Milinčić, Danijel D., Carević, Tamara, Marinković, Aleksandar, Bugarski, Branko, Marković, Tatjana, "Phytochemical Analysis, Biological Activities, and Molecular Docking Studies of Root Extracts from Paeonia Species in Serbia" in Pharmaceuticals, 17, no. 4 (2024):518,
https://doi.org/10.3390/ph17040518 . .

Optimization of the extraction process from Satureja montana L.: physicochemical characterization of the extracts

Čutović, Natalija; Batinić, Petar; Marković, Tatjana; Radanović, Dragoja; Marinković, Aleksandar; Bugarski, Branko; Jovanović, Aleksandra A.

(Savez hemijskih inženjera Srbije, 2023)

TY  - JOUR
AU  - Čutović, Natalija
AU  - Batinić, Petar
AU  - Marković, Tatjana
AU  - Radanović, Dragoja
AU  - Marinković, Aleksandar
AU  - Bugarski, Branko
AU  - Jovanović, Aleksandra A.
PY  - 2023
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/7041
AB  - The presented study aimed to optimize polyphenol extraction from Satureja montana L. obtained from the experimental field of the Institute for Medicinal Plants Research ”Dr Josif Pančić”, Serbia, by varying the most important parameters for maceration, solid-to-solvent ratio, and extraction time. The obtained extracts were characterized regarding the total polyphenol content (TPC), total flavonoid content (TFC), antioxidant potential, extraction yield, conductivity, density, surface tension, and viscosity. The TPC and TFC were ~7 to 92 mg GAE (gallic acid equivalent)/g and 3.7 to 10.9 mg CE (catechin equivalent)/g, respectively. The highest extraction yield (86 %) as well as the highest antioxidant activities were obtained for the extracts prepared using a solid-to-solvent ratio of 1 g:50 cm3. On the other hand, the extraction time did not have a significant influence. The highest conductivity was measured in the extract prepared at a 1 g:10 cm3 ratio, while the highest density and surface tension were in the extract prepared at a 1 g:40 cm3 ratio (941 kg m-3 and 29.0 mN m-1, respectively). The highest viscosity was measured in the extract prepared at a 1 g: 20 cm3 ratio (2.89 mPa∙s). Our study shows the possibilities for the production of polyphenol-rich extract of S. montana which might be used in pharmaceutical, food, or cosmetic products.
AB  - Prikazana  studija  je  imala  za  cilj  da  optimizuje  ekstrakciju  polifenola  izbiljkeSatureja  montanaL.  sa oglednog  polja  Instituta  za proučavanjelekovitog bilja „Dr Josif Pančić“, Srbija, variranjem najvažnijih parametara  maceracije,  odnosa biljnog materijala i rastvarača,i  ekstrakcionogvremena.  Dobijeni ekstrakti su okarakterisani u pogleduukupnog sadržaja polifenola (engl.total total polyphenol content, TPC), ukupnog sadržaja flavonoida (engl.total  flavonoid  content,TFC),  antioksidativnog  potencijala, prinosa  ekstrakcije,  provodljivosti,  gustine,  površinskog  napona  i  viskoznosti. Vrednostiukupnog sadržaja polifenola(engl.Total  Polyphenol  Content -TPC)iukupnog sadržaja flavonoida (engl.Total Flavonoid  Content -TFC)su  bile  u  opsezima7,2-92,2  mg ekvivalenta  galne  kiseline  (engl.gallic  acid equivalentGAE) /g i 3,7-10,9 mgekvivalenta katehina(engl.catechinequivalentCE)/g, redom. Najveće antioksidativne  aktivnosti dobijenesu  u  ekstraktima  pripremljenim  u  odnosu biljnog  materijala  i rastvarača1g :50cm-3. Najveći prinos ekstrakcije takođe je dobijenu tom ekstraktu (86,0%), dok vreme ekstrakcije nije imalo značajan uticaj. Najveća  provodljivost  izmerena  je  u  ekstraktu  pripremljenom  u odnosu biljnog materijala i rastvarača1g :10cm-3. Najvećagustina i površinski napon su bili u ekstraktu pripremljenom u odnosu 1g :40cm-3(941 kg m-3i 29,0 mNm-1, redom). Najvećaviskoznostje izmerenau  ekstraktu  pripremljenom  u  odnosu  1g :20cm-3(2,89 mPa∙s). Naša studija pokazuje mogućnosti  za proizvodnju  polifenolima  bogatog  ekstraktabiljkeS.  montanakoji se može koristiti u farmaceutskim, prehrambenim ili kozmetičkim proizvodima.
PB  - Savez hemijskih inženjera Srbije
T2  - Hemijska industrija
T1  - Optimization of the extraction process from Satureja montana L.: physicochemical characterization of the extracts
T1  - Optimizacija procesa ekstrakcije iz biljke Satureja montanal.: fizičkohemijska karakterizacija ekstrakata
EP  - 263
IS  - 4
SP  - 251
VL  - 77
DO  - 10.2298/HEMIND221213020C
ER  - 
@article{
author = "Čutović, Natalija and Batinić, Petar and Marković, Tatjana and Radanović, Dragoja and Marinković, Aleksandar and Bugarski, Branko and Jovanović, Aleksandra A.",
year = "2023",
abstract = "The presented study aimed to optimize polyphenol extraction from Satureja montana L. obtained from the experimental field of the Institute for Medicinal Plants Research ”Dr Josif Pančić”, Serbia, by varying the most important parameters for maceration, solid-to-solvent ratio, and extraction time. The obtained extracts were characterized regarding the total polyphenol content (TPC), total flavonoid content (TFC), antioxidant potential, extraction yield, conductivity, density, surface tension, and viscosity. The TPC and TFC were ~7 to 92 mg GAE (gallic acid equivalent)/g and 3.7 to 10.9 mg CE (catechin equivalent)/g, respectively. The highest extraction yield (86 %) as well as the highest antioxidant activities were obtained for the extracts prepared using a solid-to-solvent ratio of 1 g:50 cm3. On the other hand, the extraction time did not have a significant influence. The highest conductivity was measured in the extract prepared at a 1 g:10 cm3 ratio, while the highest density and surface tension were in the extract prepared at a 1 g:40 cm3 ratio (941 kg m-3 and 29.0 mN m-1, respectively). The highest viscosity was measured in the extract prepared at a 1 g: 20 cm3 ratio (2.89 mPa∙s). Our study shows the possibilities for the production of polyphenol-rich extract of S. montana which might be used in pharmaceutical, food, or cosmetic products., Prikazana  studija  je  imala  za  cilj  da  optimizuje  ekstrakciju  polifenola  izbiljkeSatureja  montanaL.  sa oglednog  polja  Instituta  za proučavanjelekovitog bilja „Dr Josif Pančić“, Srbija, variranjem najvažnijih parametara  maceracije,  odnosa biljnog materijala i rastvarača,i  ekstrakcionogvremena.  Dobijeni ekstrakti su okarakterisani u pogleduukupnog sadržaja polifenola (engl.total total polyphenol content, TPC), ukupnog sadržaja flavonoida (engl.total  flavonoid  content,TFC),  antioksidativnog  potencijala, prinosa  ekstrakcije,  provodljivosti,  gustine,  površinskog  napona  i  viskoznosti. Vrednostiukupnog sadržaja polifenola(engl.Total  Polyphenol  Content -TPC)iukupnog sadržaja flavonoida (engl.Total Flavonoid  Content -TFC)su  bile  u  opsezima7,2-92,2  mg ekvivalenta  galne  kiseline  (engl.gallic  acid equivalentGAE) /g i 3,7-10,9 mgekvivalenta katehina(engl.catechinequivalentCE)/g, redom. Najveće antioksidativne  aktivnosti dobijenesu  u  ekstraktima  pripremljenim  u  odnosu biljnog  materijala  i rastvarača1g :50cm-3. Najveći prinos ekstrakcije takođe je dobijenu tom ekstraktu (86,0%), dok vreme ekstrakcije nije imalo značajan uticaj. Najveća  provodljivost  izmerena  je  u  ekstraktu  pripremljenom  u odnosu biljnog materijala i rastvarača1g :10cm-3. Najvećagustina i površinski napon su bili u ekstraktu pripremljenom u odnosu 1g :40cm-3(941 kg m-3i 29,0 mNm-1, redom). Najvećaviskoznostje izmerenau  ekstraktu  pripremljenom  u  odnosu  1g :20cm-3(2,89 mPa∙s). Naša studija pokazuje mogućnosti  za proizvodnju  polifenolima  bogatog  ekstraktabiljkeS.  montanakoji se može koristiti u farmaceutskim, prehrambenim ili kozmetičkim proizvodima.",
publisher = "Savez hemijskih inženjera Srbije",
journal = "Hemijska industrija",
title = "Optimization of the extraction process from Satureja montana L.: physicochemical characterization of the extracts, Optimizacija procesa ekstrakcije iz biljke Satureja montanal.: fizičkohemijska karakterizacija ekstrakata",
pages = "263-251",
number = "4",
volume = "77",
doi = "10.2298/HEMIND221213020C"
}
Čutović, N., Batinić, P., Marković, T., Radanović, D., Marinković, A., Bugarski, B.,& Jovanović, A. A.. (2023). Optimization of the extraction process from Satureja montana L.: physicochemical characterization of the extracts. in Hemijska industrija
Savez hemijskih inženjera Srbije., 77(4), 251-263.
https://doi.org/10.2298/HEMIND221213020C
Čutović N, Batinić P, Marković T, Radanović D, Marinković A, Bugarski B, Jovanović AA. Optimization of the extraction process from Satureja montana L.: physicochemical characterization of the extracts. in Hemijska industrija. 2023;77(4):251-263.
doi:10.2298/HEMIND221213020C .
Čutović, Natalija, Batinić, Petar, Marković, Tatjana, Radanović, Dragoja, Marinković, Aleksandar, Bugarski, Branko, Jovanović, Aleksandra A., "Optimization of the extraction process from Satureja montana L.: physicochemical characterization of the extracts" in Hemijska industrija, 77, no. 4 (2023):251-263,
https://doi.org/10.2298/HEMIND221213020C . .

Liposomal and Liposomes-Film Systems as Carriers for Bioactives from Paeonia tenuifolia L. Petals: Physicochemical Characterization and Biological Potential

Čutović, Natalija; Marković, Tatjana; Carević, Tamara; Stojković, Dejan; Bugarski, Branko; Jovanović, Aleksandra A.

(MDPI, 2023)

TY  - JOUR
AU  - Čutović, Natalija
AU  - Marković, Tatjana
AU  - Carević, Tamara
AU  - Stojković, Dejan
AU  - Bugarski, Branko
AU  - Jovanović, Aleksandra A.
PY  - 2023
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/7073
AB  - Paeonia tenuifolia L. (steppe peony) petal extract was proficiently encapsulated into liposomes and biopolymer films in the current work, both times utilizing a single-step procedure. The encapsulation efficiency, size of the particles, and index of polydispersity (PDI), as well as the ζ potential of the obtained liposomes were determined, whereas in the case of films, the test included moisture content and mechanical property assessment. Fourier transform infrared spectroscopy (FT-IR) was used to evaluate the chemical composition and existence of numerous interactions in the systems. All the obtained encapsulates were subjected to antibacterial, antifungal and antibiofilm activity testing of the pathogens associated with human skin. The results indicated that the liposomes prepared using Phospholipon had the highest encapsulation efficiency (72.04%), making them the most favorable ones in the release study as well. The biological assays also revealed that Phospholipon was the most beneficial phospholipid mixture for the preparation of liposomes, whereas the film containing these liposomes did not have the ability to inhibit pathogen growth, making the double encapsulation of P. tenuifolia L. petal extract needless. These findings may be a first step toward the potential use of steppe peony extract-loaded films and liposomes in pharmaceutical and cosmetical industries.
PB  - MDPI
T2  - Pharmaceutics
T1  - Liposomal and Liposomes-Film Systems as Carriers for Bioactives from Paeonia tenuifolia L. Petals: Physicochemical Characterization and Biological Potential
IS  - 12
SP  - 2742
VL  - 15
DO  - 10.3390/pharmaceutics15122742
ER  - 
@article{
author = "Čutović, Natalija and Marković, Tatjana and Carević, Tamara and Stojković, Dejan and Bugarski, Branko and Jovanović, Aleksandra A.",
year = "2023",
abstract = "Paeonia tenuifolia L. (steppe peony) petal extract was proficiently encapsulated into liposomes and biopolymer films in the current work, both times utilizing a single-step procedure. The encapsulation efficiency, size of the particles, and index of polydispersity (PDI), as well as the ζ potential of the obtained liposomes were determined, whereas in the case of films, the test included moisture content and mechanical property assessment. Fourier transform infrared spectroscopy (FT-IR) was used to evaluate the chemical composition and existence of numerous interactions in the systems. All the obtained encapsulates were subjected to antibacterial, antifungal and antibiofilm activity testing of the pathogens associated with human skin. The results indicated that the liposomes prepared using Phospholipon had the highest encapsulation efficiency (72.04%), making them the most favorable ones in the release study as well. The biological assays also revealed that Phospholipon was the most beneficial phospholipid mixture for the preparation of liposomes, whereas the film containing these liposomes did not have the ability to inhibit pathogen growth, making the double encapsulation of P. tenuifolia L. petal extract needless. These findings may be a first step toward the potential use of steppe peony extract-loaded films and liposomes in pharmaceutical and cosmetical industries.",
publisher = "MDPI",
journal = "Pharmaceutics",
title = "Liposomal and Liposomes-Film Systems as Carriers for Bioactives from Paeonia tenuifolia L. Petals: Physicochemical Characterization and Biological Potential",
number = "12",
pages = "2742",
volume = "15",
doi = "10.3390/pharmaceutics15122742"
}
Čutović, N., Marković, T., Carević, T., Stojković, D., Bugarski, B.,& Jovanović, A. A.. (2023). Liposomal and Liposomes-Film Systems as Carriers for Bioactives from Paeonia tenuifolia L. Petals: Physicochemical Characterization and Biological Potential. in Pharmaceutics
MDPI., 15(12), 2742.
https://doi.org/10.3390/pharmaceutics15122742
Čutović N, Marković T, Carević T, Stojković D, Bugarski B, Jovanović AA. Liposomal and Liposomes-Film Systems as Carriers for Bioactives from Paeonia tenuifolia L. Petals: Physicochemical Characterization and Biological Potential. in Pharmaceutics. 2023;15(12):2742.
doi:10.3390/pharmaceutics15122742 .
Čutović, Natalija, Marković, Tatjana, Carević, Tamara, Stojković, Dejan, Bugarski, Branko, Jovanović, Aleksandra A., "Liposomal and Liposomes-Film Systems as Carriers for Bioactives from Paeonia tenuifolia L. Petals: Physicochemical Characterization and Biological Potential" in Pharmaceutics, 15, no. 12 (2023):2742,
https://doi.org/10.3390/pharmaceutics15122742 . .

Chemical Profile and Skin-Beneficial Activities of the Petal Extracts of Paeonia tenuifolia L. from Serbia

Čutović, Natalija; Marković, Tatjana; Kostić, Marina; Gašić, Uroš; Prijić, Željana; Ren, Xiuxia; Lukić, Milan; Bugarski, Branko

(MDPI, 2022)

TY  - JOUR
AU  - Čutović, Natalija
AU  - Marković, Tatjana
AU  - Kostić, Marina
AU  - Gašić, Uroš
AU  - Prijić, Željana
AU  - Ren, Xiuxia
AU  - Lukić, Milan
AU  - Bugarski, Branko
PY  - 2022
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/5298
AB  - Without being aware of its chemical makeup, many ancient societies have used Steppe peony in their traditional medicine. Given that modern phytopreparation intended for use on human skin requires, above all, knowledge of its chemical composition, the goal of this study was to make a screening of the composition of aqueous and methanolic extracts of the petals of P. tenuifolia L. and to examine them for various skin-beneficial properties. The extracts were prepared by maceration, ultrasound-assisted, and microwave-assisted extraction procedures. The chemical profiling was conducted by the use of UHPLC-LTQ-OrbiTrap MS and UHPLC/MS, and spectrophotometric methods for the determination of total polyphenol and total flavonoid contents. The biological activities entailed antioxidant ABTS, DPPH, CUPRAC (Cupric Ion Reducing Antioxidant Capacity), and FRAP (Ferric Reducing Antioxidant Power) assays, antimicrobial (antibacterial and antifungal) and antibiofilm activities, cytotoxicity, wound healing potential, as well as the adhesion and invasion of Staphylococcus lugdunensis. The results showed that the petals are rich in phenolic acids and flavonoids, which are commonly associated with numerous biological activities. The aqueous extracts were more efficient in the majority of the bioactivity assays then the methanolic ones, whereas the optimal extraction method varied between the assays. This study is the first step towards the safe use of the aqueous extracts of P. tenuifolia petals for therapeutic skin treatments.
PB  - MDPI
T2  - Pharmaceuticals
T1  - Chemical Profile and Skin-Beneficial Activities of the Petal Extracts of Paeonia tenuifolia L. from Serbia
IS  - 12
SP  - 1537
VL  - 15
DO  - 10.3390/ph15121537
ER  - 
@article{
author = "Čutović, Natalija and Marković, Tatjana and Kostić, Marina and Gašić, Uroš and Prijić, Željana and Ren, Xiuxia and Lukić, Milan and Bugarski, Branko",
year = "2022",
abstract = "Without being aware of its chemical makeup, many ancient societies have used Steppe peony in their traditional medicine. Given that modern phytopreparation intended for use on human skin requires, above all, knowledge of its chemical composition, the goal of this study was to make a screening of the composition of aqueous and methanolic extracts of the petals of P. tenuifolia L. and to examine them for various skin-beneficial properties. The extracts were prepared by maceration, ultrasound-assisted, and microwave-assisted extraction procedures. The chemical profiling was conducted by the use of UHPLC-LTQ-OrbiTrap MS and UHPLC/MS, and spectrophotometric methods for the determination of total polyphenol and total flavonoid contents. The biological activities entailed antioxidant ABTS, DPPH, CUPRAC (Cupric Ion Reducing Antioxidant Capacity), and FRAP (Ferric Reducing Antioxidant Power) assays, antimicrobial (antibacterial and antifungal) and antibiofilm activities, cytotoxicity, wound healing potential, as well as the adhesion and invasion of Staphylococcus lugdunensis. The results showed that the petals are rich in phenolic acids and flavonoids, which are commonly associated with numerous biological activities. The aqueous extracts were more efficient in the majority of the bioactivity assays then the methanolic ones, whereas the optimal extraction method varied between the assays. This study is the first step towards the safe use of the aqueous extracts of P. tenuifolia petals for therapeutic skin treatments.",
publisher = "MDPI",
journal = "Pharmaceuticals",
title = "Chemical Profile and Skin-Beneficial Activities of the Petal Extracts of Paeonia tenuifolia L. from Serbia",
number = "12",
pages = "1537",
volume = "15",
doi = "10.3390/ph15121537"
}
Čutović, N., Marković, T., Kostić, M., Gašić, U., Prijić, Ž., Ren, X., Lukić, M.,& Bugarski, B.. (2022). Chemical Profile and Skin-Beneficial Activities of the Petal Extracts of Paeonia tenuifolia L. from Serbia. in Pharmaceuticals
MDPI., 15(12), 1537.
https://doi.org/10.3390/ph15121537
Čutović N, Marković T, Kostić M, Gašić U, Prijić Ž, Ren X, Lukić M, Bugarski B. Chemical Profile and Skin-Beneficial Activities of the Petal Extracts of Paeonia tenuifolia L. from Serbia. in Pharmaceuticals. 2022;15(12):1537.
doi:10.3390/ph15121537 .
Čutović, Natalija, Marković, Tatjana, Kostić, Marina, Gašić, Uroš, Prijić, Željana, Ren, Xiuxia, Lukić, Milan, Bugarski, Branko, "Chemical Profile and Skin-Beneficial Activities of the Petal Extracts of Paeonia tenuifolia L. from Serbia" in Pharmaceuticals, 15, no. 12 (2022):1537,
https://doi.org/10.3390/ph15121537 . .
9
7

The preliminary comparative analysis of different routes for tio2 nanoparticles synthesis and their deposition on textiles. The methyl-orange degradation and vx detoxication study

Senić, Željko; Bauk, Sonja; Simić, Danica; Vitorović-Todorović, Maja; Marković, Tatjana; Radojković, Anton; Rajić, Dušan

(Inst Materials Physics, Bucharest, 2013)

TY  - JOUR
AU  - Senić, Željko
AU  - Bauk, Sonja
AU  - Simić, Danica
AU  - Vitorović-Todorović, Maja
AU  - Marković, Tatjana
AU  - Radojković, Anton
AU  - Rajić, Dušan
PY  - 2013
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/2424
AB  - The world-wide use of pesticides together with the possibility of chemical warfare agent's usage in military actions, terrorist attacks or in accidents, increased the risks of chemical contamination occurrence and consequently stipulated the need for the development of new protective materials and equipment with improved properties. Because of that, today in the world, research are directed toward design of the so-called "smart textiles", which are capable of "self-decontamination", i.e. decomposition of toxic chemicals. Therefore, we investigated two methods for the synthesis of TiO2 nanoparticles and their deposition on the standard military textiles (cotton/polyester 50%). Photocatalytic activity of such obtained textiles was tested by degradation of organic dye methyl orange (MeO) and chemical warfare agent O-ethyl S-(2-diisopropylamino)ethyl methylphosphonothiolate (VX), along with the evaluation of their mechanical properties, tearing strength, tensile strength and air permeability.
PB  - Inst Materials Physics, Bucharest
T2  - Digest Journal of Nanomaterials and Biostructures
T1  - The preliminary comparative analysis of different routes for tio2 nanoparticles synthesis and their deposition on textiles. The methyl-orange degradation and vx detoxication study
EP  - 719
IS  - 2
SP  - 711
VL  - 8
UR  - https://hdl.handle.net/21.15107/rcub_technorep_2424
ER  - 
@article{
author = "Senić, Željko and Bauk, Sonja and Simić, Danica and Vitorović-Todorović, Maja and Marković, Tatjana and Radojković, Anton and Rajić, Dušan",
year = "2013",
abstract = "The world-wide use of pesticides together with the possibility of chemical warfare agent's usage in military actions, terrorist attacks or in accidents, increased the risks of chemical contamination occurrence and consequently stipulated the need for the development of new protective materials and equipment with improved properties. Because of that, today in the world, research are directed toward design of the so-called "smart textiles", which are capable of "self-decontamination", i.e. decomposition of toxic chemicals. Therefore, we investigated two methods for the synthesis of TiO2 nanoparticles and their deposition on the standard military textiles (cotton/polyester 50%). Photocatalytic activity of such obtained textiles was tested by degradation of organic dye methyl orange (MeO) and chemical warfare agent O-ethyl S-(2-diisopropylamino)ethyl methylphosphonothiolate (VX), along with the evaluation of their mechanical properties, tearing strength, tensile strength and air permeability.",
publisher = "Inst Materials Physics, Bucharest",
journal = "Digest Journal of Nanomaterials and Biostructures",
title = "The preliminary comparative analysis of different routes for tio2 nanoparticles synthesis and their deposition on textiles. The methyl-orange degradation and vx detoxication study",
pages = "719-711",
number = "2",
volume = "8",
url = "https://hdl.handle.net/21.15107/rcub_technorep_2424"
}
Senić, Ž., Bauk, S., Simić, D., Vitorović-Todorović, M., Marković, T., Radojković, A.,& Rajić, D.. (2013). The preliminary comparative analysis of different routes for tio2 nanoparticles synthesis and their deposition on textiles. The methyl-orange degradation and vx detoxication study. in Digest Journal of Nanomaterials and Biostructures
Inst Materials Physics, Bucharest., 8(2), 711-719.
https://hdl.handle.net/21.15107/rcub_technorep_2424
Senić Ž, Bauk S, Simić D, Vitorović-Todorović M, Marković T, Radojković A, Rajić D. The preliminary comparative analysis of different routes for tio2 nanoparticles synthesis and their deposition on textiles. The methyl-orange degradation and vx detoxication study. in Digest Journal of Nanomaterials and Biostructures. 2013;8(2):711-719.
https://hdl.handle.net/21.15107/rcub_technorep_2424 .
Senić, Željko, Bauk, Sonja, Simić, Danica, Vitorović-Todorović, Maja, Marković, Tatjana, Radojković, Anton, Rajić, Dušan, "The preliminary comparative analysis of different routes for tio2 nanoparticles synthesis and their deposition on textiles. The methyl-orange degradation and vx detoxication study" in Digest Journal of Nanomaterials and Biostructures, 8, no. 2 (2013):711-719,
https://hdl.handle.net/21.15107/rcub_technorep_2424 .
6

A comparative study of the field of view and the optical properties of oculars of military protective masks

Rajić, Dušan; Marković, Tatjana; Ivanković, Negovan; Ilić, Marina; Senić, Željko; Vitorović-Todorović, Maja

(Military Technical Institute, Belgrade, 2012)

TY  - JOUR
AU  - Rajić, Dušan
AU  - Marković, Tatjana
AU  - Ivanković, Negovan
AU  - Ilić, Marina
AU  - Senić, Željko
AU  - Vitorović-Todorović, Maja
PY  - 2012
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/2068
AB  - A large field of view and the corresponding optical characteristics of the ocular are among the most important tactical and technical demands placed upon the designer of protective masks, because these properties directly affect the combat effectiveness of soldiers in conditions where protective mask must be worn in a protective position because of a real radioactive, chemical and biological danger. In terms of stated properties, a new domestic protective mask, marked M3, is expected to match the quality level of modern foreign military protective masks and to be better than the existing protective masks Serbian Armed Forces (SAF) are equipped with. This new mask is in the process of adoption in the armament and military equipment of the SAF. In order to perceive fulfillment of this criterion, this paper presents the experimental results of the comparative tests of the field of view and the ocular optical properties of available samples of foreign and domestic protective masks. .
AB  - Veliko vidno polje i odgovarajuće optičke karakteristike okulara su među najznačajnijim taktičko-tehničkim zahtevima koji se postavljaju pred konstruktore zaštitne maske, jer ove karakteristike neposredno utiču na borbenu efikasnost vojnika u uslovima kada zaštitna maska mora da se nosi u zaštitnom položaju zbog realne radioaktivne, hemijske i biološke opasnosti. Od nove domaće zaštitne maske oznake M3, koja se nalazi u fazi usvajanja u naoružanje i vojnu opremu Vojske Srbije (VS), očekuje se da u pogledu navedenih karakteristika, bude bolja od postojećih zaštitnih maski kojima je trenutno opremljena VS, a na približnom nivou kvaliteta najsavremenijih inostranih vojnih zaštitnih maski. U cilju sagledavanja ispunjenosti ovog kriterijuma, u radu su prikazani eksperimentalni komparativni rezultati ispitivanja vidnog polja i optičkih karakteristika okulara na uzorcima dostupnih inostranih i domaćih zaštitnih maski.
PB  - Military Technical Institute, Belgrade
T2  - Scientific Technical Review
T1  - A comparative study of the field of view and the optical properties of oculars of military protective masks
T1  - Sravnitel'noe issledovanie polja zrenija i optičeskih svojstv glaznogo voennyh zaščitnyh masok / (francuski) Etude comparative du champ visuel et de l'oculaire optique chez le masque protecteur
T1  - Komparativna studija polja vida i optičkih osobina okulara vojnih zaštitnih maski
EP  - 93
IS  - 3-4
SP  - 87
VL  - 62
UR  - https://hdl.handle.net/21.15107/rcub_technorep_2068
ER  - 
@article{
author = "Rajić, Dušan and Marković, Tatjana and Ivanković, Negovan and Ilić, Marina and Senić, Željko and Vitorović-Todorović, Maja",
year = "2012",
abstract = "A large field of view and the corresponding optical characteristics of the ocular are among the most important tactical and technical demands placed upon the designer of protective masks, because these properties directly affect the combat effectiveness of soldiers in conditions where protective mask must be worn in a protective position because of a real radioactive, chemical and biological danger. In terms of stated properties, a new domestic protective mask, marked M3, is expected to match the quality level of modern foreign military protective masks and to be better than the existing protective masks Serbian Armed Forces (SAF) are equipped with. This new mask is in the process of adoption in the armament and military equipment of the SAF. In order to perceive fulfillment of this criterion, this paper presents the experimental results of the comparative tests of the field of view and the ocular optical properties of available samples of foreign and domestic protective masks. ., Veliko vidno polje i odgovarajuće optičke karakteristike okulara su među najznačajnijim taktičko-tehničkim zahtevima koji se postavljaju pred konstruktore zaštitne maske, jer ove karakteristike neposredno utiču na borbenu efikasnost vojnika u uslovima kada zaštitna maska mora da se nosi u zaštitnom položaju zbog realne radioaktivne, hemijske i biološke opasnosti. Od nove domaće zaštitne maske oznake M3, koja se nalazi u fazi usvajanja u naoružanje i vojnu opremu Vojske Srbije (VS), očekuje se da u pogledu navedenih karakteristika, bude bolja od postojećih zaštitnih maski kojima je trenutno opremljena VS, a na približnom nivou kvaliteta najsavremenijih inostranih vojnih zaštitnih maski. U cilju sagledavanja ispunjenosti ovog kriterijuma, u radu su prikazani eksperimentalni komparativni rezultati ispitivanja vidnog polja i optičkih karakteristika okulara na uzorcima dostupnih inostranih i domaćih zaštitnih maski.",
publisher = "Military Technical Institute, Belgrade",
journal = "Scientific Technical Review",
title = "A comparative study of the field of view and the optical properties of oculars of military protective masks, Sravnitel'noe issledovanie polja zrenija i optičeskih svojstv glaznogo voennyh zaščitnyh masok / (francuski) Etude comparative du champ visuel et de l'oculaire optique chez le masque protecteur, Komparativna studija polja vida i optičkih osobina okulara vojnih zaštitnih maski",
pages = "93-87",
number = "3-4",
volume = "62",
url = "https://hdl.handle.net/21.15107/rcub_technorep_2068"
}
Rajić, D., Marković, T., Ivanković, N., Ilić, M., Senić, Ž.,& Vitorović-Todorović, M.. (2012). A comparative study of the field of view and the optical properties of oculars of military protective masks. in Scientific Technical Review
Military Technical Institute, Belgrade., 62(3-4), 87-93.
https://hdl.handle.net/21.15107/rcub_technorep_2068
Rajić D, Marković T, Ivanković N, Ilić M, Senić Ž, Vitorović-Todorović M. A comparative study of the field of view and the optical properties of oculars of military protective masks. in Scientific Technical Review. 2012;62(3-4):87-93.
https://hdl.handle.net/21.15107/rcub_technorep_2068 .
Rajić, Dušan, Marković, Tatjana, Ivanković, Negovan, Ilić, Marina, Senić, Željko, Vitorović-Todorović, Maja, "A comparative study of the field of view and the optical properties of oculars of military protective masks" in Scientific Technical Review, 62, no. 3-4 (2012):87-93,
https://hdl.handle.net/21.15107/rcub_technorep_2068 .