TY  - JOUR
AU  - Milovanović, Stoja
AU  - Grzegorczyk, Agnieszka
AU  - Świątek, Łukasz
AU  - Grzęda, Anita
AU  - Dębczak, Agnieszka
AU  - Tyskiewicz, Katarzyna
AU  - Konkol, Marcin
PY  - 2023
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/6031
AB  - The main aim of this study was to evaluate the oils from chamomile seeds as a new source of bioactive compounds suitable for human consumption. A green extraction technique with supercritical carbon dioxide (sc-CO2) at pressures up to 450 bar and temperatures up to 60 °C was employed for the production of a high amount of biologically active oil. Additionally, exhausted waste material was re-extracted using sc-CO2 with the addition of ethanol. By optimization in operating pressure, temperature, production cost, fraction of milled seeds, and co-solvent addition, the amount of separated chamomile oil increased from 2.4 to 18.6% and the content of unsaturated fatty acids up to 88.7%. Oils contained α-bisabolol oxide A and B in amounts up to 1.4%. Linoleic acid was detected in an amount up to 711.1 mg/g and α-linolenic acid up to 27.5 mg/g. The total phenolic content in separated oil reached 80.4 mg GAE/g while the total flavonoid content reached 11.6 mg QE/g. The obtained chamomile oils showed antioxidant activity with an IC50 of up to 3.9 mg/mL. Among the 23 tested microorganisms, the antimicrobial activity of oils was the most pronounced against Gram-positive bacteria. The cytotoxic activity of oils was tested on normal and cancer-derived cell lines. Results indicated a significant potential for oil from chamomile seeds, produced in an eco-friendly manner, as a functional food.
PB  - Springer
T2  - Food and Bioprocess Technology
T1  - A Novel Strategy for the Separation of Functional Oils from Chamomile Seeds
DO  - 10.1007/s11947-023-03038-9
ER  - 

@article{
author = "Milovanović, Stoja and Grzegorczyk, Agnieszka and Świątek, Łukasz and Grzęda, Anita and Dębczak, Agnieszka and Tyskiewicz, Katarzyna and Konkol, Marcin",
year = "2023",
abstract = "The main aim of this study was to evaluate the oils from chamomile seeds as a new source of bioactive compounds suitable for human consumption. A green extraction technique with supercritical carbon dioxide (sc-CO2) at pressures up to 450 bar and temperatures up to 60 °C was employed for the production of a high amount of biologically active oil. Additionally, exhausted waste material was re-extracted using sc-CO2 with the addition of ethanol. By optimization in operating pressure, temperature, production cost, fraction of milled seeds, and co-solvent addition, the amount of separated chamomile oil increased from 2.4 to 18.6% and the content of unsaturated fatty acids up to 88.7%. Oils contained α-bisabolol oxide A and B in amounts up to 1.4%. Linoleic acid was detected in an amount up to 711.1 mg/g and α-linolenic acid up to 27.5 mg/g. The total phenolic content in separated oil reached 80.4 mg GAE/g while the total flavonoid content reached 11.6 mg QE/g. The obtained chamomile oils showed antioxidant activity with an IC50 of up to 3.9 mg/mL. Among the 23 tested microorganisms, the antimicrobial activity of oils was the most pronounced against Gram-positive bacteria. The cytotoxic activity of oils was tested on normal and cancer-derived cell lines. Results indicated a significant potential for oil from chamomile seeds, produced in an eco-friendly manner, as a functional food.",
publisher = "Springer",
journal = "Food and Bioprocess Technology",
title = "A Novel Strategy for the Separation of Functional Oils from Chamomile Seeds",
doi = "10.1007/s11947-023-03038-9"
}

Milovanović, S., Grzegorczyk, A., Świątek, Ł., Grzęda, A., Dębczak, A., Tyskiewicz, K.,& Konkol, M.. (2023). A Novel Strategy for the Separation of Functional Oils from Chamomile Seeds. in Food and Bioprocess Technology
Springer..
https://doi.org/10.1007/s11947-023-03038-9

Milovanović S, Grzegorczyk A, Świątek Ł, Grzęda A, Dębczak A, Tyskiewicz K, Konkol M. A Novel Strategy for the Separation of Functional Oils from Chamomile Seeds. in Food and Bioprocess Technology. 2023;.
doi:10.1007/s11947-023-03038-9 .

Milovanović, Stoja, Grzegorczyk, Agnieszka, Świątek, Łukasz, Grzęda, Anita, Dębczak, Agnieszka, Tyskiewicz, Katarzyna, Konkol, Marcin, "A Novel Strategy for the Separation of Functional Oils from Chamomile Seeds" in Food and Bioprocess Technology (2023),
https://doi.org/10.1007/s11947-023-03038-9 . .