TY  - JOUR
AU  - Knežević, Nikola Ž.
AU  - Mrdanović, Jasminka
AU  - Borisev, Ivana
AU  - Milenković, Sanja
AU  - Janaćković, Đorđe
AU  - Cunin, Frederique
AU  - Đorđević, Aleksandar
PY  - 2016
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3386
AB  - A novel cancer-targeting drug delivery system is constructed and characterized, based on folic acid-functionalized mesoporous silica nanoparticles with pore-loaded anticancer drug vinblastine and pore-blocking fullerenol molecules. The selective treatment efficacy based on targeting of cancer-verexpressed folate receptors is demonstrated by comparison of cell viability upon the treatment of healthy MRC-5, breast cancer MCF-7 and cervical cancer HeLa cells, which are known to differ in the amount of folate receptors on their surfaces.
PB  - Royal Society of Chemistry
T2  - RSC Advances
T1  - Hydroxylated fullerene-capped, vinblastine-loaded folic acid-functionalized mesoporous silica nanoparticles for targeted anticancer therapy
EP  - 7065
IS  - 9
SP  - 7061
VL  - 6
DO  - 10.1039/c5ra22937e
ER  - 

@article{
author = "Knežević, Nikola Ž. and Mrdanović, Jasminka and Borisev, Ivana and Milenković, Sanja and Janaćković, Đorđe and Cunin, Frederique and Đorđević, Aleksandar",
year = "2016",
abstract = "A novel cancer-targeting drug delivery system is constructed and characterized, based on folic acid-functionalized mesoporous silica nanoparticles with pore-loaded anticancer drug vinblastine and pore-blocking fullerenol molecules. The selective treatment efficacy based on targeting of cancer-verexpressed folate receptors is demonstrated by comparison of cell viability upon the treatment of healthy MRC-5, breast cancer MCF-7 and cervical cancer HeLa cells, which are known to differ in the amount of folate receptors on their surfaces.",
publisher = "Royal Society of Chemistry",
journal = "RSC Advances",
title = "Hydroxylated fullerene-capped, vinblastine-loaded folic acid-functionalized mesoporous silica nanoparticles for targeted anticancer therapy",
pages = "7065-7061",
number = "9",
volume = "6",
doi = "10.1039/c5ra22937e"
}

Knežević, N. Ž., Mrdanović, J., Borisev, I., Milenković, S., Janaćković, Đ., Cunin, F.,& Đorđević, A.. (2016). Hydroxylated fullerene-capped, vinblastine-loaded folic acid-functionalized mesoporous silica nanoparticles for targeted anticancer therapy. in RSC Advances
Royal Society of Chemistry., 6(9), 7061-7065.
https://doi.org/10.1039/c5ra22937e

Knežević NŽ, Mrdanović J, Borisev I, Milenković S, Janaćković Đ, Cunin F, Đorđević A. Hydroxylated fullerene-capped, vinblastine-loaded folic acid-functionalized mesoporous silica nanoparticles for targeted anticancer therapy. in RSC Advances. 2016;6(9):7061-7065.
doi:10.1039/c5ra22937e .

Knežević, Nikola Ž., Mrdanović, Jasminka, Borisev, Ivana, Milenković, Sanja, Janaćković, Đorđe, Cunin, Frederique, Đorđević, Aleksandar, "Hydroxylated fullerene-capped, vinblastine-loaded folic acid-functionalized mesoporous silica nanoparticles for targeted anticancer therapy" in RSC Advances, 6, no. 9 (2016):7061-7065,
https://doi.org/10.1039/c5ra22937e . .