TY  - JOUR
AU  - Filipović, Vuk
AU  - Babić, Marija
AU  - Gođevac, Dejan
AU  - Pavić, Aleksandar
AU  - Nikodinović-Runić, Jasmina
AU  - Tomić, Simonida
PY  - 2019
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4076
AB  - New (beta-aminoester) hydrogels (PBAE) based on di(ethylene glycol)diacrylate and glycine are successfully synthesized and characterized for the first time in this work. PBAE macromers are obtained using Michael addition. By changing the diacrylate/amine stoichiometric ratio, but maintaining it  gt 1, samples with different chemical structure containing acrylate end-groups are obtained. The hydrogels are synthesized from macromers utilizing free radical polymerization. Chemical structure of macromers and hydrogels is confirmed by proton nuclear magnetic resonance, and Fourier transform infra-red spectroscopy. Swelling and degradation rates in physiological pH range change notably with pH and monomer molar ratio, validating pH sensitivity and zwitterionic behavior, which can be finely tuned by changing any of these parameters. In vitro cytotoxicity and in vivo acute embryotoxicity in zebrafish (Danio rerio) performed to assess the biocompatibility of the novel hydrogel materials and their degradation products reveal that materials are nontoxic and biocompatible. The Cephalexin in vitro drug release study, at pH values 2.20, 5.50, and 7.40, demonstrates pH-sensitive delivery with the release profiles effectively controlled by pH and the hydrogel composition. PBAE hydrogels exhibit great potential for a variety of biomedical applications, including tissue regeneration and intelligent drug delivery systems.
PB  - Wiley-VCH Verlag Gmbh, Weinheim
T2  - Macromolecular Chemistry and Physics
T1  - In Vitro and In Vivo Biocompatibility of Novel Zwitterionic Poly(Beta Amino)Ester Hydrogels Based on Diacrylate and Glycine for Site-Specific Controlled Drug Release
IS  - 17
SP  - 1900188
VL  - 220
DO  - 10.1002/macp.201900188
ER  - 

@article{
author = "Filipović, Vuk and Babić, Marija and Gođevac, Dejan and Pavić, Aleksandar and Nikodinović-Runić, Jasmina and Tomić, Simonida",
year = "2019",
abstract = "New (beta-aminoester) hydrogels (PBAE) based on di(ethylene glycol)diacrylate and glycine are successfully synthesized and characterized for the first time in this work. PBAE macromers are obtained using Michael addition. By changing the diacrylate/amine stoichiometric ratio, but maintaining it  gt 1, samples with different chemical structure containing acrylate end-groups are obtained. The hydrogels are synthesized from macromers utilizing free radical polymerization. Chemical structure of macromers and hydrogels is confirmed by proton nuclear magnetic resonance, and Fourier transform infra-red spectroscopy. Swelling and degradation rates in physiological pH range change notably with pH and monomer molar ratio, validating pH sensitivity and zwitterionic behavior, which can be finely tuned by changing any of these parameters. In vitro cytotoxicity and in vivo acute embryotoxicity in zebrafish (Danio rerio) performed to assess the biocompatibility of the novel hydrogel materials and their degradation products reveal that materials are nontoxic and biocompatible. The Cephalexin in vitro drug release study, at pH values 2.20, 5.50, and 7.40, demonstrates pH-sensitive delivery with the release profiles effectively controlled by pH and the hydrogel composition. PBAE hydrogels exhibit great potential for a variety of biomedical applications, including tissue regeneration and intelligent drug delivery systems.",
publisher = "Wiley-VCH Verlag Gmbh, Weinheim",
journal = "Macromolecular Chemistry and Physics",
title = "In Vitro and In Vivo Biocompatibility of Novel Zwitterionic Poly(Beta Amino)Ester Hydrogels Based on Diacrylate and Glycine for Site-Specific Controlled Drug Release",
number = "17",
pages = "1900188",
volume = "220",
doi = "10.1002/macp.201900188"
}

Filipović, V., Babić, M., Gođevac, D., Pavić, A., Nikodinović-Runić, J.,& Tomić, S.. (2019). In Vitro and In Vivo Biocompatibility of Novel Zwitterionic Poly(Beta Amino)Ester Hydrogels Based on Diacrylate and Glycine for Site-Specific Controlled Drug Release. in Macromolecular Chemistry and Physics
Wiley-VCH Verlag Gmbh, Weinheim., 220(17), 1900188.
https://doi.org/10.1002/macp.201900188

Filipović V, Babić M, Gođevac D, Pavić A, Nikodinović-Runić J, Tomić S. In Vitro and In Vivo Biocompatibility of Novel Zwitterionic Poly(Beta Amino)Ester Hydrogels Based on Diacrylate and Glycine for Site-Specific Controlled Drug Release. in Macromolecular Chemistry and Physics. 2019;220(17):1900188.
doi:10.1002/macp.201900188 .

Filipović, Vuk, Babić, Marija, Gođevac, Dejan, Pavić, Aleksandar, Nikodinović-Runić, Jasmina, Tomić, Simonida, "In Vitro and In Vivo Biocompatibility of Novel Zwitterionic Poly(Beta Amino)Ester Hydrogels Based on Diacrylate and Glycine for Site-Specific Controlled Drug Release" in Macromolecular Chemistry and Physics, 220, no. 17 (2019):1900188,
https://doi.org/10.1002/macp.201900188 . .

TY  - JOUR
AU  - Jovanović, Aleksandra
AU  - Đorđević, Verica
AU  - Zdunić, Gordana
AU  - Pljevljakusić, Dejan
AU  - Šavikin, Katarina
AU  - Gođevac, Dejan
AU  - Bugarski, Branko
PY  - 2017
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3751
AB  - Despite the fact that Thymus serpyllum is well-known medicinal plant and its chemical profile and biological activity have been investigated, there is no detailed study regarding the influence of different techniques and conditions on the extraction of polyphenolic compounds from Serpylli herba. The aim of this study was optimization of the extraction parameters that improves the efficiency of polyphenols extraction from T. serpyllum: particle size, solid-to-solvent ratio, solvent type and extraction time, by using maceration, heat- and ultrasound-assisted extraction (HAE and UAE). The extraction efficiency was expressed via total polyphenol content (TPC) and total flavonoid content (TFC). The statistical analysis (one-way ANOVA and full factorial design) has revealed that the optimal conditions for achieving the best polyphenols yield were particle size of 0.3 mm, 1:30 solid-to-solvent ratio and 50% ethanol, as environmentally friendly extraction medium, while extraction time has not shown statistically significant influence on polyphenols concentration, in all procedures. Under these conditions, the measured TPC was 26.6 mg GAE/L in maceration, 29.8 mg GAE/L in HAE and 32.7 mg GAE/L in UAE, which was in agreement with the predicted values, while TFC was 143 mg CE/L, 12.4 mg CE/L and 16.7 mg CE/L for maceration, HAE and UAE, respectively. According to total polyphenols yield, the efficiency of the extraction methods for all variables was ranked by significance in the following order: UAE  gt  HAE  gt  maceration, whereas total flavonoids yield was the highest in UAE, although there was no statistically significant difference between maceration and HAE. According to our results, UAE could be selected as the most successful and suitable technique for extraction of bioactive polyphenolic compounds from Serpylli herba. Using LC/MS and HPLC analysis, 9 polyphenolic compounds were identified and quantified: 6,8-Di-C-glucosylapigenin, chlorogenic acid, 6-hydroxyluteolin 7-O-glucoside, caffeic acid, luteolin 7-O-glucuronide, apigenin glucuronide, salvianolic acid g isomer, rosmarinic acid and salvianolic acid I. This study was an initial step in production of polyphenols-rich wild thyme extracts aimed to be used for formulation of foodstuffs and medicines.
PB  - Elsevier Science Bv, Amsterdam
T2  - Separation and Purification Technology
T1  - Optimization of the extraction process of polyphenols from Thymus serpyllum L. herb using maceration, heat- and ultrasound-assisted techniques
EP  - 380
SP  - 369
VL  - 179
DO  - 10.1016/j.seppur.2017.01.055
ER  - 

@article{
author = "Jovanović, Aleksandra and Đorđević, Verica and Zdunić, Gordana and Pljevljakusić, Dejan and Šavikin, Katarina and Gođevac, Dejan and Bugarski, Branko",
year = "2017",
abstract = "Despite the fact that Thymus serpyllum is well-known medicinal plant and its chemical profile and biological activity have been investigated, there is no detailed study regarding the influence of different techniques and conditions on the extraction of polyphenolic compounds from Serpylli herba. The aim of this study was optimization of the extraction parameters that improves the efficiency of polyphenols extraction from T. serpyllum: particle size, solid-to-solvent ratio, solvent type and extraction time, by using maceration, heat- and ultrasound-assisted extraction (HAE and UAE). The extraction efficiency was expressed via total polyphenol content (TPC) and total flavonoid content (TFC). The statistical analysis (one-way ANOVA and full factorial design) has revealed that the optimal conditions for achieving the best polyphenols yield were particle size of 0.3 mm, 1:30 solid-to-solvent ratio and 50% ethanol, as environmentally friendly extraction medium, while extraction time has not shown statistically significant influence on polyphenols concentration, in all procedures. Under these conditions, the measured TPC was 26.6 mg GAE/L in maceration, 29.8 mg GAE/L in HAE and 32.7 mg GAE/L in UAE, which was in agreement with the predicted values, while TFC was 143 mg CE/L, 12.4 mg CE/L and 16.7 mg CE/L for maceration, HAE and UAE, respectively. According to total polyphenols yield, the efficiency of the extraction methods for all variables was ranked by significance in the following order: UAE  gt  HAE  gt  maceration, whereas total flavonoids yield was the highest in UAE, although there was no statistically significant difference between maceration and HAE. According to our results, UAE could be selected as the most successful and suitable technique for extraction of bioactive polyphenolic compounds from Serpylli herba. Using LC/MS and HPLC analysis, 9 polyphenolic compounds were identified and quantified: 6,8-Di-C-glucosylapigenin, chlorogenic acid, 6-hydroxyluteolin 7-O-glucoside, caffeic acid, luteolin 7-O-glucuronide, apigenin glucuronide, salvianolic acid g isomer, rosmarinic acid and salvianolic acid I. This study was an initial step in production of polyphenols-rich wild thyme extracts aimed to be used for formulation of foodstuffs and medicines.",
publisher = "Elsevier Science Bv, Amsterdam",
journal = "Separation and Purification Technology",
title = "Optimization of the extraction process of polyphenols from Thymus serpyllum L. herb using maceration, heat- and ultrasound-assisted techniques",
pages = "380-369",
volume = "179",
doi = "10.1016/j.seppur.2017.01.055"
}

Jovanović, A., Đorđević, V., Zdunić, G., Pljevljakusić, D., Šavikin, K., Gođevac, D.,& Bugarski, B.. (2017). Optimization of the extraction process of polyphenols from Thymus serpyllum L. herb using maceration, heat- and ultrasound-assisted techniques. in Separation and Purification Technology
Elsevier Science Bv, Amsterdam., 179, 369-380.
https://doi.org/10.1016/j.seppur.2017.01.055

Jovanović A, Đorđević V, Zdunić G, Pljevljakusić D, Šavikin K, Gođevac D, Bugarski B. Optimization of the extraction process of polyphenols from Thymus serpyllum L. herb using maceration, heat- and ultrasound-assisted techniques. in Separation and Purification Technology. 2017;179:369-380.
doi:10.1016/j.seppur.2017.01.055 .

Jovanović, Aleksandra, Đorđević, Verica, Zdunić, Gordana, Pljevljakusić, Dejan, Šavikin, Katarina, Gođevac, Dejan, Bugarski, Branko, "Optimization of the extraction process of polyphenols from Thymus serpyllum L. herb using maceration, heat- and ultrasound-assisted techniques" in Separation and Purification Technology, 179 (2017):369-380,
https://doi.org/10.1016/j.seppur.2017.01.055 . .

TY  - JOUR
AU  - Vajić, Una-Jovana
AU  - Grujić-Milanović, Jelica
AU  - Živković, Jelena Č.
AU  - Šavikin, Katarina
AU  - Gođevac, Dejan
AU  - Miloradović, Zoran
AU  - Bugarski, Branko
AU  - Mihailović-Stanojević, Nevena
PY  - 2015
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3145
AB  - A full three level factorial design was implemented for optimization of extraction parameters in order to maximize total phenolic (TP) yield from stinging nettle leaf. Factors considered were percentage of methanol in solvent (X-1 : 50-100% methanol) and extraction time (X-2: 30-90 min), and maceration was used as extraction method. A second-order polynomial model was applied for fitting experimental data and predicting the response, and this mathematical model produced a satisfactory fit (R-2 = 0.993,p lt 0.01). The optimal extraction conditions were 54% aqueous methanol and 38 min extraction time, while maximal theoretical TP yield was 8.9 mg GAE/g DW. Solvent composition significantly affected extraction efficiency causing decrease of TP yield with increase of methanol percentage. On the other hand, extraction time did not influence significantly efficiency of extraction. Using LC/MS and HPLC analysis we detected and quantified three most abundant phenolic compounds: 2-O-caffeoyl malic acid, chlorogenic acid, and rutin. Comparison between maceration and ultrasound-assisted extraction (UAE) obtained extracts based on TP content as well as antiradical activity and HPLC results, showed that UAE have a better extraction capability affecting yield and time of extraction. Of all tested extracts, 54% aqueous methanolic extracts obtained with UAE and 38 min extraction time had the highest TP content.
PB  - Elsevier, Amsterdam
T2  - Industrial Crops and Products
T1  - Optimization of extraction of stinging nettle leaf phenolic compounds using response surface methodology
EP  - 917
SP  - 912
VL  - 74
DO  - 10.1016/j.indcrop.2015.06.032
ER  - 

@article{
author = "Vajić, Una-Jovana and Grujić-Milanović, Jelica and Živković, Jelena Č. and Šavikin, Katarina and Gođevac, Dejan and Miloradović, Zoran and Bugarski, Branko and Mihailović-Stanojević, Nevena",
year = "2015",
abstract = "A full three level factorial design was implemented for optimization of extraction parameters in order to maximize total phenolic (TP) yield from stinging nettle leaf. Factors considered were percentage of methanol in solvent (X-1 : 50-100% methanol) and extraction time (X-2: 30-90 min), and maceration was used as extraction method. A second-order polynomial model was applied for fitting experimental data and predicting the response, and this mathematical model produced a satisfactory fit (R-2 = 0.993,p lt 0.01). The optimal extraction conditions were 54% aqueous methanol and 38 min extraction time, while maximal theoretical TP yield was 8.9 mg GAE/g DW. Solvent composition significantly affected extraction efficiency causing decrease of TP yield with increase of methanol percentage. On the other hand, extraction time did not influence significantly efficiency of extraction. Using LC/MS and HPLC analysis we detected and quantified three most abundant phenolic compounds: 2-O-caffeoyl malic acid, chlorogenic acid, and rutin. Comparison between maceration and ultrasound-assisted extraction (UAE) obtained extracts based on TP content as well as antiradical activity and HPLC results, showed that UAE have a better extraction capability affecting yield and time of extraction. Of all tested extracts, 54% aqueous methanolic extracts obtained with UAE and 38 min extraction time had the highest TP content.",
publisher = "Elsevier, Amsterdam",
journal = "Industrial Crops and Products",
title = "Optimization of extraction of stinging nettle leaf phenolic compounds using response surface methodology",
pages = "917-912",
volume = "74",
doi = "10.1016/j.indcrop.2015.06.032"
}

Vajić, U., Grujić-Milanović, J., Živković, J. Č., Šavikin, K., Gođevac, D., Miloradović, Z., Bugarski, B.,& Mihailović-Stanojević, N.. (2015). Optimization of extraction of stinging nettle leaf phenolic compounds using response surface methodology. in Industrial Crops and Products
Elsevier, Amsterdam., 74, 912-917.
https://doi.org/10.1016/j.indcrop.2015.06.032

Vajić U, Grujić-Milanović J, Živković JČ, Šavikin K, Gođevac D, Miloradović Z, Bugarski B, Mihailović-Stanojević N. Optimization of extraction of stinging nettle leaf phenolic compounds using response surface methodology. in Industrial Crops and Products. 2015;74:912-917.
doi:10.1016/j.indcrop.2015.06.032 .

Vajić, Una-Jovana, Grujić-Milanović, Jelica, Živković, Jelena Č., Šavikin, Katarina, Gođevac, Dejan, Miloradović, Zoran, Bugarski, Branko, Mihailović-Stanojević, Nevena, "Optimization of extraction of stinging nettle leaf phenolic compounds using response surface methodology" in Industrial Crops and Products, 74 (2015):912-917,
https://doi.org/10.1016/j.indcrop.2015.06.032 . .

TY  - JOUR
AU  - Pergal, Marija
AU  - Stefanović, Ivan
AU  - Gođevac, Dejan
AU  - Antić, Vesna
AU  - Milačić, Vesna
AU  - Ostojić, Sanja
AU  - Rogan, Jelena
AU  - Đonlagić, Jasna
PY  - 2014
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/2692
AB  - In this study, the synthesis, structure and physical properties of two series of thermoplastic polyurethanes based on hydroxypropyl-terminated poly(dimethylsiloxane) (HP-PDMS) or hydroxyethoxypropyl-terminated poly(dimethylsiloxane) (EO-PDMS) as soft segments, and 4,4'-methylenediphenyl diisocyanate and 1,4-butanediol as hard segments were investigated. The polyurethanes were synthesized by two-step polyaddition in solution. The effects of the type and content of PDMS segments on the structure, thermal and surface properties of copolymers were studied by H-1-, C-13-nuclear magnetic resonance (NMR) spectroscopy and two-dimensional NMR spectroscopies (heteronuclear multiple bond correlation (HMBC) and rotating-frame nuclear Overhauser effect (ROESY)), gel permeation chromatography (GPC), differential scanning calorimetry (DSC), thermogravimetric analysis (TGA), wide-angle X-ray scattering (WAXS), scanning electron microscopy (SEM) and water contact angle and water absorption measurements. Thermal properties investigated by DSC indicated that the presence of soft PDMS segments lowers the glass transition and melting temperatures of the hard phase as well as the degree of crystallinity. SEM analysis of the copolymers with a lower soft segment content confirmed the presence of spherulite superstructures, which arise from the crystallization of the hard segments. When compared with polyurethanes prepared from HP-PDMS, the copolymers synthesized from EO-PDMS with the same content of the soft segments had a higher degree of crystallinity, better thermal stability and a less hydrophobic surface. The obtained results showed that the synthesized polyurethanes had good thermal and surface properties, which could be further modified by changing the type or content of the soft segments.
PB  - Srpsko hemijsko društvo, Beograd
T2  - Journal of the Serbian Chemical Society
T1  - Structural, thermal and surface characterization of thermoplastic polyurethanes based on poly(dimethylsiloxane)
EP  - +
IS  - 7
SP  - 843
VL  - 79
DO  - 10.2298/JSC130819149P
ER  - 

@article{
author = "Pergal, Marija and Stefanović, Ivan and Gođevac, Dejan and Antić, Vesna and Milačić, Vesna and Ostojić, Sanja and Rogan, Jelena and Đonlagić, Jasna",
year = "2014",
abstract = "In this study, the synthesis, structure and physical properties of two series of thermoplastic polyurethanes based on hydroxypropyl-terminated poly(dimethylsiloxane) (HP-PDMS) or hydroxyethoxypropyl-terminated poly(dimethylsiloxane) (EO-PDMS) as soft segments, and 4,4'-methylenediphenyl diisocyanate and 1,4-butanediol as hard segments were investigated. The polyurethanes were synthesized by two-step polyaddition in solution. The effects of the type and content of PDMS segments on the structure, thermal and surface properties of copolymers were studied by H-1-, C-13-nuclear magnetic resonance (NMR) spectroscopy and two-dimensional NMR spectroscopies (heteronuclear multiple bond correlation (HMBC) and rotating-frame nuclear Overhauser effect (ROESY)), gel permeation chromatography (GPC), differential scanning calorimetry (DSC), thermogravimetric analysis (TGA), wide-angle X-ray scattering (WAXS), scanning electron microscopy (SEM) and water contact angle and water absorption measurements. Thermal properties investigated by DSC indicated that the presence of soft PDMS segments lowers the glass transition and melting temperatures of the hard phase as well as the degree of crystallinity. SEM analysis of the copolymers with a lower soft segment content confirmed the presence of spherulite superstructures, which arise from the crystallization of the hard segments. When compared with polyurethanes prepared from HP-PDMS, the copolymers synthesized from EO-PDMS with the same content of the soft segments had a higher degree of crystallinity, better thermal stability and a less hydrophobic surface. The obtained results showed that the synthesized polyurethanes had good thermal and surface properties, which could be further modified by changing the type or content of the soft segments.",
publisher = "Srpsko hemijsko društvo, Beograd",
journal = "Journal of the Serbian Chemical Society",
title = "Structural, thermal and surface characterization of thermoplastic polyurethanes based on poly(dimethylsiloxane)",
pages = "+-843",
number = "7",
volume = "79",
doi = "10.2298/JSC130819149P"
}

Pergal, M., Stefanović, I., Gođevac, D., Antić, V., Milačić, V., Ostojić, S., Rogan, J.,& Đonlagić, J.. (2014). Structural, thermal and surface characterization of thermoplastic polyurethanes based on poly(dimethylsiloxane). in Journal of the Serbian Chemical Society
Srpsko hemijsko društvo, Beograd., 79(7), 843-+.
https://doi.org/10.2298/JSC130819149P

Pergal M, Stefanović I, Gođevac D, Antić V, Milačić V, Ostojić S, Rogan J, Đonlagić J. Structural, thermal and surface characterization of thermoplastic polyurethanes based on poly(dimethylsiloxane). in Journal of the Serbian Chemical Society. 2014;79(7):843-+.
doi:10.2298/JSC130819149P .

Pergal, Marija, Stefanović, Ivan, Gođevac, Dejan, Antić, Vesna, Milačić, Vesna, Ostojić, Sanja, Rogan, Jelena, Đonlagić, Jasna, "Structural, thermal and surface characterization of thermoplastic polyurethanes based on poly(dimethylsiloxane)" in Journal of the Serbian Chemical Society, 79, no. 7 (2014):843-+,
https://doi.org/10.2298/JSC130819149P . .

TY  - JOUR
AU  - Balaban, Milica
AU  - Antić, Vesna
AU  - Pergal, Marija
AU  - Gođevac, Dejan
AU  - Francolini, Iolanda
AU  - Martinelli, Andrea
AU  - Rogan, Jelena
AU  - Đonlagić, Jasna
PY  - 2013
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/2500
AB  - Segmented poly(urethane-urea-siloxane)s (PUUS) were synthesized using 4,4'-methylenediphenyl diisocyanate (MDI) and ethylene diamine (ED) as the hard segment components and hydroxypropyl-terminated poly(dimethylsiloxane) (PDMS) as the soft segment component, where the hard segment content ranged from 38 to 65 wt%. Segmented PUUSs were prepared by a two-step polymerization procedure in tetrahydrofuran/N-methylpyrrolidone (THF/NMP) mixture with a large proportion of polar solvent. The structure, composition and hard segment length were determined by C-13 NMR and two-dimensional correlation spectroscopy. Thermal, mechanical, small-angle X-ray scattering and hydrogen bonding analyses indicated the formation of the microphase-separated copolymers with high tensile strength. Globular superstructures observed in the copolymer films by scanning electron microscopy (SEM) and atomic force microscopy (AFM) were probably arisen from the microstructural organization of the MDI-ED segments, depending on their content and length. The PUUS copolymers showed high water resistance and became more hydrophobic with increasing weight fraction of PDMS.
PB  - Springer, New York
T2  - Polymer Bulletin
T1  - Influence of the chemical structure of poly(urea-urethane-siloxane)s on their morphological, surface and thermal properties
EP  - 2518
IS  - 9
SP  - 2493
VL  - 70
DO  - 10.1007/s00289-013-0968-2
ER  - 

@article{
author = "Balaban, Milica and Antić, Vesna and Pergal, Marija and Gođevac, Dejan and Francolini, Iolanda and Martinelli, Andrea and Rogan, Jelena and Đonlagić, Jasna",
year = "2013",
abstract = "Segmented poly(urethane-urea-siloxane)s (PUUS) were synthesized using 4,4'-methylenediphenyl diisocyanate (MDI) and ethylene diamine (ED) as the hard segment components and hydroxypropyl-terminated poly(dimethylsiloxane) (PDMS) as the soft segment component, where the hard segment content ranged from 38 to 65 wt%. Segmented PUUSs were prepared by a two-step polymerization procedure in tetrahydrofuran/N-methylpyrrolidone (THF/NMP) mixture with a large proportion of polar solvent. The structure, composition and hard segment length were determined by C-13 NMR and two-dimensional correlation spectroscopy. Thermal, mechanical, small-angle X-ray scattering and hydrogen bonding analyses indicated the formation of the microphase-separated copolymers with high tensile strength. Globular superstructures observed in the copolymer films by scanning electron microscopy (SEM) and atomic force microscopy (AFM) were probably arisen from the microstructural organization of the MDI-ED segments, depending on their content and length. The PUUS copolymers showed high water resistance and became more hydrophobic with increasing weight fraction of PDMS.",
publisher = "Springer, New York",
journal = "Polymer Bulletin",
title = "Influence of the chemical structure of poly(urea-urethane-siloxane)s on their morphological, surface and thermal properties",
pages = "2518-2493",
number = "9",
volume = "70",
doi = "10.1007/s00289-013-0968-2"
}

Balaban, M., Antić, V., Pergal, M., Gođevac, D., Francolini, I., Martinelli, A., Rogan, J.,& Đonlagić, J.. (2013). Influence of the chemical structure of poly(urea-urethane-siloxane)s on their morphological, surface and thermal properties. in Polymer Bulletin
Springer, New York., 70(9), 2493-2518.
https://doi.org/10.1007/s00289-013-0968-2

Balaban M, Antić V, Pergal M, Gođevac D, Francolini I, Martinelli A, Rogan J, Đonlagić J. Influence of the chemical structure of poly(urea-urethane-siloxane)s on their morphological, surface and thermal properties. in Polymer Bulletin. 2013;70(9):2493-2518.
doi:10.1007/s00289-013-0968-2 .

Balaban, Milica, Antić, Vesna, Pergal, Marija, Gođevac, Dejan, Francolini, Iolanda, Martinelli, Andrea, Rogan, Jelena, Đonlagić, Jasna, "Influence of the chemical structure of poly(urea-urethane-siloxane)s on their morphological, surface and thermal properties" in Polymer Bulletin, 70, no. 9 (2013):2493-2518,
https://doi.org/10.1007/s00289-013-0968-2 . .

TY  - JOUR
AU  - Pergal, Marija
AU  - Antić, Vesna
AU  - Govedarica, Milutin
AU  - Gođevac, Dejan
AU  - Ostojić, Sanja
AU  - Đonlagić, Jasna
PY  - 2011
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/5658
AB  - Novel polyurethane copolymers derived from 4,4'-methylenediphenyl diisocyanate (MDI), 1,4-butanediol (BD) and alpha, omega-dihydroxy-[poly(caprolactone)-poly (dimethylsiloxane)-poly(caprolactone)] (a, x-dihydroxy( PCL-PDMS-PCL); (M) over bar (n) 6100 g mol(-1)) were synthesized by a two-step polyaddition reaction in solution. In the synthesis of the polyurethanes, the PCL blocks served as a compatibilizer between the nonpolar PDMS blocks and the polar comonomers, MDI and BD. The synthesis of thermoplastic polyurethanes (TPU) with high soft segment contents was optimized in terms of the concentrations of the reactants, the molar ratio of the NCO/OH groups, and the time and temperature of the polyaddition reaction. The structure, composition, and hard MDI/BD segment length of the synthesized polyurethane copolymers were determined by H-1, C-13-NMR, and two-dimensional correlation (COSY, HSQC, and HMBC) spectroscopy, while the hydrogen bonding interactions in the copolymers were analyzed by FT-IR spectroscopy. The influence of the reaction conditions on the structure, molecular weight, thermal, and some physical properties was studied at constant composition of the reaction mixture. A change in the molar ratio of the NCO/OH groups and the reaction conditions modified not only the molecular weight of the synthesized polyurethanes, but also the microstructure and therefore the thermal and physical properties of the copolymers. It was demonstrated that only PCL segments with high soft segment contents crystallize, thereby showing spherulitic morphology.
PB  - Wiley-Blackwell, Malden
T2  - Journal of Applied Polymer Science
T1  - Synthesis and Characterization of Novel Urethane-Siloxane Copolymers with a High Content of PCL-PDMS-PCL Segments
EP  - 2730
IS  - 4
SP  - 2715
VL  - 122
DO  - 10.1002/app.33926
ER  - 

@article{
author = "Pergal, Marija and Antić, Vesna and Govedarica, Milutin and Gođevac, Dejan and Ostojić, Sanja and Đonlagić, Jasna",
year = "2011",
abstract = "Novel polyurethane copolymers derived from 4,4'-methylenediphenyl diisocyanate (MDI), 1,4-butanediol (BD) and alpha, omega-dihydroxy-[poly(caprolactone)-poly (dimethylsiloxane)-poly(caprolactone)] (a, x-dihydroxy( PCL-PDMS-PCL); (M) over bar (n) 6100 g mol(-1)) were synthesized by a two-step polyaddition reaction in solution. In the synthesis of the polyurethanes, the PCL blocks served as a compatibilizer between the nonpolar PDMS blocks and the polar comonomers, MDI and BD. The synthesis of thermoplastic polyurethanes (TPU) with high soft segment contents was optimized in terms of the concentrations of the reactants, the molar ratio of the NCO/OH groups, and the time and temperature of the polyaddition reaction. The structure, composition, and hard MDI/BD segment length of the synthesized polyurethane copolymers were determined by H-1, C-13-NMR, and two-dimensional correlation (COSY, HSQC, and HMBC) spectroscopy, while the hydrogen bonding interactions in the copolymers were analyzed by FT-IR spectroscopy. The influence of the reaction conditions on the structure, molecular weight, thermal, and some physical properties was studied at constant composition of the reaction mixture. A change in the molar ratio of the NCO/OH groups and the reaction conditions modified not only the molecular weight of the synthesized polyurethanes, but also the microstructure and therefore the thermal and physical properties of the copolymers. It was demonstrated that only PCL segments with high soft segment contents crystallize, thereby showing spherulitic morphology.",
publisher = "Wiley-Blackwell, Malden",
journal = "Journal of Applied Polymer Science",
title = "Synthesis and Characterization of Novel Urethane-Siloxane Copolymers with a High Content of PCL-PDMS-PCL Segments",
pages = "2730-2715",
number = "4",
volume = "122",
doi = "10.1002/app.33926"
}

Pergal, M., Antić, V., Govedarica, M., Gođevac, D., Ostojić, S.,& Đonlagić, J.. (2011). Synthesis and Characterization of Novel Urethane-Siloxane Copolymers with a High Content of PCL-PDMS-PCL Segments. in Journal of Applied Polymer Science
Wiley-Blackwell, Malden., 122(4), 2715-2730.
https://doi.org/10.1002/app.33926

Pergal M, Antić V, Govedarica M, Gođevac D, Ostojić S, Đonlagić J. Synthesis and Characterization of Novel Urethane-Siloxane Copolymers with a High Content of PCL-PDMS-PCL Segments. in Journal of Applied Polymer Science. 2011;122(4):2715-2730.
doi:10.1002/app.33926 .

Pergal, Marija, Antić, Vesna, Govedarica, Milutin, Gođevac, Dejan, Ostojić, Sanja, Đonlagić, Jasna, "Synthesis and Characterization of Novel Urethane-Siloxane Copolymers with a High Content of PCL-PDMS-PCL Segments" in Journal of Applied Polymer Science, 122, no. 4 (2011):2715-2730,
https://doi.org/10.1002/app.33926 . .

TY  - JOUR
AU  - Filipović, Nenad R.
AU  - Todorović, Tamara
AU  - Marković, Rade
AU  - Marinković, Aleksandar
AU  - Tufegdžić, Srđan
AU  - Gođevac, Dejan
AU  - Anđelković, Katarina K.
PY  - 2010
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/1629
AB  - Condensation derivatives of ethyl hydrazinoacetate with 2-formylpyridine and quinoline-2-carboxaldehyde were synthesized. Pd(II), Pt(II) and Cd(II) complexes with the 2-formylpyridine derivative and a Cd(II) complex with the quinoline-2-carboxaldehyde derivative were synthesized and characterized by spectroscopic techniques. In the complexes, both ligands are coordinated in neutral NN bidentate modes, while the remaining two coordination sites are occupied by chloride. All compounds showed biological activity when tested against Escherichia coli, Bacillus subtilis and Staphylococcus aureus.
PB  - Springer, Dordrecht
T2  - Transition Metal Chemistry
T1  - Synthesis, characterization and biological activities of N-heteroaromatic hydrazones and their complexes with Pd(II), Pt(II) and Cd(II)
EP  - 772
IS  - 6
SP  - 765
VL  - 35
DO  - 10.1007/s11243-010-9391-9
ER  - 

@article{
author = "Filipović, Nenad R. and Todorović, Tamara and Marković, Rade and Marinković, Aleksandar and Tufegdžić, Srđan and Gođevac, Dejan and Anđelković, Katarina K.",
year = "2010",
abstract = "Condensation derivatives of ethyl hydrazinoacetate with 2-formylpyridine and quinoline-2-carboxaldehyde were synthesized. Pd(II), Pt(II) and Cd(II) complexes with the 2-formylpyridine derivative and a Cd(II) complex with the quinoline-2-carboxaldehyde derivative were synthesized and characterized by spectroscopic techniques. In the complexes, both ligands are coordinated in neutral NN bidentate modes, while the remaining two coordination sites are occupied by chloride. All compounds showed biological activity when tested against Escherichia coli, Bacillus subtilis and Staphylococcus aureus.",
publisher = "Springer, Dordrecht",
journal = "Transition Metal Chemistry",
title = "Synthesis, characterization and biological activities of N-heteroaromatic hydrazones and their complexes with Pd(II), Pt(II) and Cd(II)",
pages = "772-765",
number = "6",
volume = "35",
doi = "10.1007/s11243-010-9391-9"
}

Filipović, N. R., Todorović, T., Marković, R., Marinković, A., Tufegdžić, S., Gođevac, D.,& Anđelković, K. K.. (2010). Synthesis, characterization and biological activities of N-heteroaromatic hydrazones and their complexes with Pd(II), Pt(II) and Cd(II). in Transition Metal Chemistry
Springer, Dordrecht., 35(6), 765-772.
https://doi.org/10.1007/s11243-010-9391-9

Filipović NR, Todorović T, Marković R, Marinković A, Tufegdžić S, Gođevac D, Anđelković KK. Synthesis, characterization and biological activities of N-heteroaromatic hydrazones and their complexes with Pd(II), Pt(II) and Cd(II). in Transition Metal Chemistry. 2010;35(6):765-772.
doi:10.1007/s11243-010-9391-9 .

Filipović, Nenad R., Todorović, Tamara, Marković, Rade, Marinković, Aleksandar, Tufegdžić, Srđan, Gođevac, Dejan, Anđelković, Katarina K., "Synthesis, characterization and biological activities of N-heteroaromatic hydrazones and their complexes with Pd(II), Pt(II) and Cd(II)" in Transition Metal Chemistry, 35, no. 6 (2010):765-772,
https://doi.org/10.1007/s11243-010-9391-9 . .