TY  - JOUR
AU  - Ležaja, Maja
AU  - Veljović, Đorđe
AU  - Manojlović, Dragica
AU  - Milošević, Miloš
AU  - Mitrović, Nenad
AU  - Janaćković, Đorđe
AU  - Miletić, Vesna
PY  - 2015
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3036
AB  - Objective. To determine the shear bond strength (SBS) between synthetic controlled porous hydroxyapatite (HAP) inserts and restorative materials and dimensional changes of insert-containing restorations during curing. Methods. Cylinder-shaped HAP inserts (4 mm in diameter, 1.6 mm thick) were cemented in dentin discs (5 mm x 1.6 mm), cut mid-coronally from human third molars, using one of the following materials: universal microhybrid composite Filtek Z250, flowable composite Filtek Ultimate or glass-ionomer Vitrebond (all 3M ESPE). SBS of the same materials to HAP inserts was tested in a universal testing machine. Three-dimensional digital image correlation system Aramis (GOM) was used to measure strains and displacements. Data were statistically analyzed using one-way ANOVA with Tukey's post-test (alpha = 0.05). Results. SBS of restorative materials to HAP inserts ranged between 12.2 +/- 2.1 MPa (Filtek Z250) and 0.7 +/- 0.4 MPa (Filtek Z250 without an adhesive). The 'total-etch' approach of adhesive application significantly increased SBS of both Filtek Z250 (12.2 +/- 2.1 MPa) and Filtek Ultimate flowable (9.5 +/- 2.5 MPa) compared to the 'self-etch' approach (8.2 +/- 1.6 MPa and 4.4 +/- 0.9 MPa, respectively) (p  lt  0.05). HAP inserts reduced polymerization shrinkage to below 0.5% as well as displacements in the central region of the restorations. Peripheral shrinkage of restorative materials was similar with and without HAP inserts as were displacements of Filtek Z250 and Vitrebond. Significance. Replacing major part of dentin clinically, especially in large cavities, HAP inserts may shorten clinical working time, improve dimensional stability of the restoration by reducing central shrinkage and displacements and provide adhesive bonding to universal composites following a 'total-etch' approach.
PB  - Elsevier Sci Ltd, Oxford
T2  - Dental Materials
T1  - Bond strength of restorative materials to hydroxyapatite inserts and dimensional changes of insert-containing restorations during polymerization
EP  - 181
IS  - 2
SP  - 171
VL  - 31
DO  - 10.1016/j.dental.2014.11.017
ER  - 

@article{
author = "Ležaja, Maja and Veljović, Đorđe and Manojlović, Dragica and Milošević, Miloš and Mitrović, Nenad and Janaćković, Đorđe and Miletić, Vesna",
year = "2015",
abstract = "Objective. To determine the shear bond strength (SBS) between synthetic controlled porous hydroxyapatite (HAP) inserts and restorative materials and dimensional changes of insert-containing restorations during curing. Methods. Cylinder-shaped HAP inserts (4 mm in diameter, 1.6 mm thick) were cemented in dentin discs (5 mm x 1.6 mm), cut mid-coronally from human third molars, using one of the following materials: universal microhybrid composite Filtek Z250, flowable composite Filtek Ultimate or glass-ionomer Vitrebond (all 3M ESPE). SBS of the same materials to HAP inserts was tested in a universal testing machine. Three-dimensional digital image correlation system Aramis (GOM) was used to measure strains and displacements. Data were statistically analyzed using one-way ANOVA with Tukey's post-test (alpha = 0.05). Results. SBS of restorative materials to HAP inserts ranged between 12.2 +/- 2.1 MPa (Filtek Z250) and 0.7 +/- 0.4 MPa (Filtek Z250 without an adhesive). The 'total-etch' approach of adhesive application significantly increased SBS of both Filtek Z250 (12.2 +/- 2.1 MPa) and Filtek Ultimate flowable (9.5 +/- 2.5 MPa) compared to the 'self-etch' approach (8.2 +/- 1.6 MPa and 4.4 +/- 0.9 MPa, respectively) (p  lt  0.05). HAP inserts reduced polymerization shrinkage to below 0.5% as well as displacements in the central region of the restorations. Peripheral shrinkage of restorative materials was similar with and without HAP inserts as were displacements of Filtek Z250 and Vitrebond. Significance. Replacing major part of dentin clinically, especially in large cavities, HAP inserts may shorten clinical working time, improve dimensional stability of the restoration by reducing central shrinkage and displacements and provide adhesive bonding to universal composites following a 'total-etch' approach.",
publisher = "Elsevier Sci Ltd, Oxford",
journal = "Dental Materials",
title = "Bond strength of restorative materials to hydroxyapatite inserts and dimensional changes of insert-containing restorations during polymerization",
pages = "181-171",
number = "2",
volume = "31",
doi = "10.1016/j.dental.2014.11.017"
}

Ležaja, M., Veljović, Đ., Manojlović, D., Milošević, M., Mitrović, N., Janaćković, Đ.,& Miletić, V.. (2015). Bond strength of restorative materials to hydroxyapatite inserts and dimensional changes of insert-containing restorations during polymerization. in Dental Materials
Elsevier Sci Ltd, Oxford., 31(2), 171-181.
https://doi.org/10.1016/j.dental.2014.11.017

Ležaja M, Veljović Đ, Manojlović D, Milošević M, Mitrović N, Janaćković Đ, Miletić V. Bond strength of restorative materials to hydroxyapatite inserts and dimensional changes of insert-containing restorations during polymerization. in Dental Materials. 2015;31(2):171-181.
doi:10.1016/j.dental.2014.11.017 .

Ležaja, Maja, Veljović, Đorđe, Manojlović, Dragica, Milošević, Miloš, Mitrović, Nenad, Janaćković, Đorđe, Miletić, Vesna, "Bond strength of restorative materials to hydroxyapatite inserts and dimensional changes of insert-containing restorations during polymerization" in Dental Materials, 31, no. 2 (2015):171-181,
https://doi.org/10.1016/j.dental.2014.11.017 . .

TY  - JOUR
AU  - Manojlović, Dragica
AU  - Radisić, Marina
AU  - Laušević, Mila
AU  - Živković, Slavoljub
AU  - Miletić, Vesna
PY  - 2013
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/5704
AB  - Elution of potentially toxic substances, including monomers, from resin-based dental composites may affect the biocompatibility of these materials in clinical conditions. In addition to the amounts of eluted monomers, mathematical modeling of elution kinetics reveals composite restorations as potential chronic sources of leachable monomers. The aim of this work was to experimentally quantify elution of main cross-linking monomers from four commercial composites and offer a mathematical model of elution kinetics. Composite samples (n = 7 per group) of Filtek Supreme XT (3M ESPE), Tetric EvoCeram (Ivoclar Vivadent), Admira (Voco), and Filtek Z250 (3M ESPE) were prepared in 2-mm thick Teflon moulds and cured with halogen or light-emitting diode light. Monomer elution in ethanol and water was analyzed using high-performance liquid chromatography up to 28 days postimmersion. The mathematical model was expressed as a sum of two exponential regression functions representing the first-order kinetics law. Elution kinetics in all cases followed the same mathematical model though differences in rate constants as well as the extent of monomer elution were material-, LCU-, medium-dependent. The proposed mechanisms of elution indicate fast elution from surface and subsurface layers and up to 100 times slower monomer extraction from the bulk polymer.
PB  - Wiley-Blackwell, Hoboken
T2  - Journal of Biomedical Materials Research Part B: Applied Biomaterials
T1  - Mathematical modeling of cross-linking monomer elution from resin-based dental composites
EP  - 67
IS  - 1
SP  - 61
VL  - 101B
DO  - 10.1002/jbm.b.32815
ER  - 

@article{
author = "Manojlović, Dragica and Radisić, Marina and Laušević, Mila and Živković, Slavoljub and Miletić, Vesna",
year = "2013",
abstract = "Elution of potentially toxic substances, including monomers, from resin-based dental composites may affect the biocompatibility of these materials in clinical conditions. In addition to the amounts of eluted monomers, mathematical modeling of elution kinetics reveals composite restorations as potential chronic sources of leachable monomers. The aim of this work was to experimentally quantify elution of main cross-linking monomers from four commercial composites and offer a mathematical model of elution kinetics. Composite samples (n = 7 per group) of Filtek Supreme XT (3M ESPE), Tetric EvoCeram (Ivoclar Vivadent), Admira (Voco), and Filtek Z250 (3M ESPE) were prepared in 2-mm thick Teflon moulds and cured with halogen or light-emitting diode light. Monomer elution in ethanol and water was analyzed using high-performance liquid chromatography up to 28 days postimmersion. The mathematical model was expressed as a sum of two exponential regression functions representing the first-order kinetics law. Elution kinetics in all cases followed the same mathematical model though differences in rate constants as well as the extent of monomer elution were material-, LCU-, medium-dependent. The proposed mechanisms of elution indicate fast elution from surface and subsurface layers and up to 100 times slower monomer extraction from the bulk polymer.",
publisher = "Wiley-Blackwell, Hoboken",
journal = "Journal of Biomedical Materials Research Part B: Applied Biomaterials",
title = "Mathematical modeling of cross-linking monomer elution from resin-based dental composites",
pages = "67-61",
number = "1",
volume = "101B",
doi = "10.1002/jbm.b.32815"
}

Manojlović, D., Radisić, M., Laušević, M., Živković, S.,& Miletić, V.. (2013). Mathematical modeling of cross-linking monomer elution from resin-based dental composites. in Journal of Biomedical Materials Research Part B: Applied Biomaterials
Wiley-Blackwell, Hoboken., 101B(1), 61-67.
https://doi.org/10.1002/jbm.b.32815

Manojlović D, Radisić M, Laušević M, Živković S, Miletić V. Mathematical modeling of cross-linking monomer elution from resin-based dental composites. in Journal of Biomedical Materials Research Part B: Applied Biomaterials. 2013;101B(1):61-67.
doi:10.1002/jbm.b.32815 .

Manojlović, Dragica, Radisić, Marina, Laušević, Mila, Živković, Slavoljub, Miletić, Vesna, "Mathematical modeling of cross-linking monomer elution from resin-based dental composites" in Journal of Biomedical Materials Research Part B: Applied Biomaterials, 101B, no. 1 (2013):61-67,
https://doi.org/10.1002/jbm.b.32815 . .

TY  - JOUR
AU  - Manojlović, Dragica
AU  - Radisić, Marina
AU  - Vasiljević, Tatjana
AU  - Živković, Slavoljub
AU  - Laušević, Mila
AU  - Miletić, Vesna
PY  - 2011
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/5640
AB  - Objectives. To study monomer elution from four resin-based composites (RBCs) cured with different light sources. Methods. Twenty-eight premolars were randomly allocated to four groups. Standardized cavities were prepared and restored with a nanohybrid (Filtek Supreme XT or Tetric EvoCeram), an ormocer (Admira) or a microhybrid RBC (Filtek Z250) which served as control. Buccal restorations were cured with a halogen and oral restorations with an LED light-curing unit. Elution of diurethane dimethacrylate (UDMA), Bisphenol A diglycidylether methacrylate (BisGMA), triethylene glycol dimethacrylate (TEGDMA) and 2-hydroxyethyl methacrylate (HEMA) was analyzed using high-performance liquid chromatography (HPLC) 1h to 28 days post-immersion in 75% ethanol. Data were analyzed using multivariate and repeated measures analysis of variance (alpha = 0.05). Results. The greatest elution of UDMA and BisGMA occurred from Tetric EvoCeram and the least from Filtek Z250 (p  lt  0.05). LED and halogen light-curing units gave similar results for all RBCs (p > 0.05) except Tetric EvoCeram which showed greater elution for the LED unit (p  lt  0.05). TEGDMA was below the limit of quantification. HEMA eluted in similar concentrations from Filtek Supreme and Tetric EvoCeram (p > 0.05). Significance. : The two nanohybrid RBCs eluted more cross-linking monomers than the ormocer and the control microhybrid RBC. Continuous elution over 28 days indicates that RBCs act as a chronic source of monomers in clinical conditions. Light source may affect monomer elution since differences were found for one out of four RBCs. Mathematical models for elution kinetics of UDMA and BisGMA indicated two elution mechanisms.
PB  - Elsevier Sci Ltd, Oxford
T2  - Dental Materials
T1  - Monomer elution from nanohybrid and ormocer-based composites cured with different light sources
EP  - 378
IS  - 4
SP  - 371
VL  - 27
DO  - 10.1016/j.dental.2010.11.017
ER  - 

@article{
author = "Manojlović, Dragica and Radisić, Marina and Vasiljević, Tatjana and Živković, Slavoljub and Laušević, Mila and Miletić, Vesna",
year = "2011",
abstract = "Objectives. To study monomer elution from four resin-based composites (RBCs) cured with different light sources. Methods. Twenty-eight premolars were randomly allocated to four groups. Standardized cavities were prepared and restored with a nanohybrid (Filtek Supreme XT or Tetric EvoCeram), an ormocer (Admira) or a microhybrid RBC (Filtek Z250) which served as control. Buccal restorations were cured with a halogen and oral restorations with an LED light-curing unit. Elution of diurethane dimethacrylate (UDMA), Bisphenol A diglycidylether methacrylate (BisGMA), triethylene glycol dimethacrylate (TEGDMA) and 2-hydroxyethyl methacrylate (HEMA) was analyzed using high-performance liquid chromatography (HPLC) 1h to 28 days post-immersion in 75% ethanol. Data were analyzed using multivariate and repeated measures analysis of variance (alpha = 0.05). Results. The greatest elution of UDMA and BisGMA occurred from Tetric EvoCeram and the least from Filtek Z250 (p  lt  0.05). LED and halogen light-curing units gave similar results for all RBCs (p > 0.05) except Tetric EvoCeram which showed greater elution for the LED unit (p  lt  0.05). TEGDMA was below the limit of quantification. HEMA eluted in similar concentrations from Filtek Supreme and Tetric EvoCeram (p > 0.05). Significance. : The two nanohybrid RBCs eluted more cross-linking monomers than the ormocer and the control microhybrid RBC. Continuous elution over 28 days indicates that RBCs act as a chronic source of monomers in clinical conditions. Light source may affect monomer elution since differences were found for one out of four RBCs. Mathematical models for elution kinetics of UDMA and BisGMA indicated two elution mechanisms.",
publisher = "Elsevier Sci Ltd, Oxford",
journal = "Dental Materials",
title = "Monomer elution from nanohybrid and ormocer-based composites cured with different light sources",
pages = "378-371",
number = "4",
volume = "27",
doi = "10.1016/j.dental.2010.11.017"
}

Manojlović, D., Radisić, M., Vasiljević, T., Živković, S., Laušević, M.,& Miletić, V.. (2011). Monomer elution from nanohybrid and ormocer-based composites cured with different light sources. in Dental Materials
Elsevier Sci Ltd, Oxford., 27(4), 371-378.
https://doi.org/10.1016/j.dental.2010.11.017

Manojlović D, Radisić M, Vasiljević T, Živković S, Laušević M, Miletić V. Monomer elution from nanohybrid and ormocer-based composites cured with different light sources. in Dental Materials. 2011;27(4):371-378.
doi:10.1016/j.dental.2010.11.017 .

Manojlović, Dragica, Radisić, Marina, Vasiljević, Tatjana, Živković, Slavoljub, Laušević, Mila, Miletić, Vesna, "Monomer elution from nanohybrid and ormocer-based composites cured with different light sources" in Dental Materials, 27, no. 4 (2011):371-378,
https://doi.org/10.1016/j.dental.2010.11.017 . .