TY  - JOUR
AU  - Stamenovic, Una
AU  - Davidović, Slađana
AU  - Petrovic, Sandra
AU  - Leskovac, Andreja
AU  - Stoiljkovic, Milovan
AU  - Vodnik, Vesna
PY  - 2021
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4852
AB  - Two silver-polyaniline/polyvinylpyrrolidone (Ag-PANI/PVP) nanocomposites were prepared using in situ integration of silver nanoparticles (AgNPs) during oxidative aniline polymerization, accelerated by the presence of PVP, which as well minimized the risk of particle agglomeration and macroscopic precipitation. Both nanocomposites have similar silver content (similar to 44 wt% Ag) but different morphological features of AgNPs (spheres/triangles) and polymers (granular/wrinkling pattern). Several spectroscopic, macroscopic, and analytical techniques, microscopy, and surface analysis methods have been used to analyze their physical and chemical properties. Investigation of their antimicrobial potential and possible application as an effective weapon against indicator microbial strains, E. coli, S. aureus, and C. albicans, has shown inhibition of microbial growth by more than 90%, even at low composite concentrations (5 ppm) and short contact time (4 h). A biosafety assessment of Ag-PANI/PVP that comprised testing the genotoxicity and redox modulating activity was performed using human peripheral blood cells as a model system. The obtained results have shown that the investigated Ag-PANI/PVP exhibited significant prooxidant and cytostatic effects (p   lt 0.05) with no apparent potential to induce DNA damage. Although precautions should be taken to protect human health, the significant antimicrobial efficiency of Ag-PANI/PVP makes it suitable for further studies and applications in non-medical areas, such as wastewater treatment.
T2  - New Journal of Chemistry
T1  - Antimicrobial and biological effects of polyaniline/polyvinylpyrrolidone nanocomposites loaded with silver nanospheres/triangles
EP  - 12720
IS  - 28
SP  - 12711
VL  - 45
DO  - 10.1039/d1nj02729h
ER  - 

@article{
author = "Stamenovic, Una and Davidović, Slađana and Petrovic, Sandra and Leskovac, Andreja and Stoiljkovic, Milovan and Vodnik, Vesna",
year = "2021",
abstract = "Two silver-polyaniline/polyvinylpyrrolidone (Ag-PANI/PVP) nanocomposites were prepared using in situ integration of silver nanoparticles (AgNPs) during oxidative aniline polymerization, accelerated by the presence of PVP, which as well minimized the risk of particle agglomeration and macroscopic precipitation. Both nanocomposites have similar silver content (similar to 44 wt% Ag) but different morphological features of AgNPs (spheres/triangles) and polymers (granular/wrinkling pattern). Several spectroscopic, macroscopic, and analytical techniques, microscopy, and surface analysis methods have been used to analyze their physical and chemical properties. Investigation of their antimicrobial potential and possible application as an effective weapon against indicator microbial strains, E. coli, S. aureus, and C. albicans, has shown inhibition of microbial growth by more than 90%, even at low composite concentrations (5 ppm) and short contact time (4 h). A biosafety assessment of Ag-PANI/PVP that comprised testing the genotoxicity and redox modulating activity was performed using human peripheral blood cells as a model system. The obtained results have shown that the investigated Ag-PANI/PVP exhibited significant prooxidant and cytostatic effects (p   lt 0.05) with no apparent potential to induce DNA damage. Although precautions should be taken to protect human health, the significant antimicrobial efficiency of Ag-PANI/PVP makes it suitable for further studies and applications in non-medical areas, such as wastewater treatment.",
journal = "New Journal of Chemistry",
title = "Antimicrobial and biological effects of polyaniline/polyvinylpyrrolidone nanocomposites loaded with silver nanospheres/triangles",
pages = "12720-12711",
number = "28",
volume = "45",
doi = "10.1039/d1nj02729h"
}

Stamenovic, U., Davidović, S., Petrovic, S., Leskovac, A., Stoiljkovic, M.,& Vodnik, V.. (2021). Antimicrobial and biological effects of polyaniline/polyvinylpyrrolidone nanocomposites loaded with silver nanospheres/triangles. in New Journal of Chemistry, 45(28), 12711-12720.
https://doi.org/10.1039/d1nj02729h

Stamenovic U, Davidović S, Petrovic S, Leskovac A, Stoiljkovic M, Vodnik V. Antimicrobial and biological effects of polyaniline/polyvinylpyrrolidone nanocomposites loaded with silver nanospheres/triangles. in New Journal of Chemistry. 2021;45(28):12711-12720.
doi:10.1039/d1nj02729h .

Stamenovic, Una, Davidović, Slađana, Petrovic, Sandra, Leskovac, Andreja, Stoiljkovic, Milovan, Vodnik, Vesna, "Antimicrobial and biological effects of polyaniline/polyvinylpyrrolidone nanocomposites loaded with silver nanospheres/triangles" in New Journal of Chemistry, 45, no. 28 (2021):12711-12720,
https://doi.org/10.1039/d1nj02729h . .