TY  - JOUR
AU  - Dimić, Ivana
AU  - Cvijović-Alagić, Ivana
AU  - Hohenwarter, Anton
AU  - Pippan, Reinhard
AU  - Kojić, Vesna
AU  - Bajat, Jelena
AU  - Rakin, Marko
PY  - 2018
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3963
AB  - The purpose of this study was to estimate the electrochemical behavior and biocompatibility of ultrafine-grained (UFG) commercially pure titanium (CPTi) and Ti-13Nb-13Zr (TNZ) alloy obtained by high-pressure torsion process. Electrochemical behavior of materials in artificial saliva at 37 degrees C was evaluated by potentiodynamic polarization tests and electrochemical impedance spectroscopy (EIS), and the obtained results indicated that UFG TNZ alloy showed corrosion current density (j(corr)=53 +/- 5 nA cm(-2)) which was 2 times lower compared to coarse-grained (CG) TNZ alloy (j(corr)=110 +/- 12 nA cm(-2)) and higher corrosion resistance, while UFG CPTi and CPTi showed approximately the same corrosion rate (mean j(corr) approximate to 38-40 nA cm(-2)). Static immersion test in artificial saliva, performed in this study, showed that the released ion concentrations from UFG materials were more than 10 times lower than the permitted concentration (the highest released Ti ion concentration from UFG CPTi and UFG TNZ alloy was 1.12 and 1.28 ppb, respectively, while permitted concentration was 15.5 ppb). The in vitro cytotoxicity tests, as the initial phase of the biocompatibility evaluation, showed that the fraction of surviving cells in all examined materials was much higher compared to the control sample and hence demonstrated absence of cytotoxicity and an increase of fibroblast cells adhesion on UFG materials surfaces. UFG CPTi and UFG TNZ alloy can be considered as promising materials for applications in dentistry due to high corrosion resistance and outstanding biocompatibility which were shown in this study.
PB  - Wiley, Hoboken
T2  - Journal of Biomedical Materials Research Part B-Applied Biomaterials
T1  - Electrochemical and biocompatibility examinations of high-pressure torsion processed titanium and Ti-13Nb-13Zr alloy
EP  - 1107
IS  - 3
SP  - 1097
VL  - 106
DO  - 10.1002/jbm.b.33919
ER  - 

@article{
author = "Dimić, Ivana and Cvijović-Alagić, Ivana and Hohenwarter, Anton and Pippan, Reinhard and Kojić, Vesna and Bajat, Jelena and Rakin, Marko",
year = "2018",
abstract = "The purpose of this study was to estimate the electrochemical behavior and biocompatibility of ultrafine-grained (UFG) commercially pure titanium (CPTi) and Ti-13Nb-13Zr (TNZ) alloy obtained by high-pressure torsion process. Electrochemical behavior of materials in artificial saliva at 37 degrees C was evaluated by potentiodynamic polarization tests and electrochemical impedance spectroscopy (EIS), and the obtained results indicated that UFG TNZ alloy showed corrosion current density (j(corr)=53 +/- 5 nA cm(-2)) which was 2 times lower compared to coarse-grained (CG) TNZ alloy (j(corr)=110 +/- 12 nA cm(-2)) and higher corrosion resistance, while UFG CPTi and CPTi showed approximately the same corrosion rate (mean j(corr) approximate to 38-40 nA cm(-2)). Static immersion test in artificial saliva, performed in this study, showed that the released ion concentrations from UFG materials were more than 10 times lower than the permitted concentration (the highest released Ti ion concentration from UFG CPTi and UFG TNZ alloy was 1.12 and 1.28 ppb, respectively, while permitted concentration was 15.5 ppb). The in vitro cytotoxicity tests, as the initial phase of the biocompatibility evaluation, showed that the fraction of surviving cells in all examined materials was much higher compared to the control sample and hence demonstrated absence of cytotoxicity and an increase of fibroblast cells adhesion on UFG materials surfaces. UFG CPTi and UFG TNZ alloy can be considered as promising materials for applications in dentistry due to high corrosion resistance and outstanding biocompatibility which were shown in this study.",
publisher = "Wiley, Hoboken",
journal = "Journal of Biomedical Materials Research Part B-Applied Biomaterials",
title = "Electrochemical and biocompatibility examinations of high-pressure torsion processed titanium and Ti-13Nb-13Zr alloy",
pages = "1107-1097",
number = "3",
volume = "106",
doi = "10.1002/jbm.b.33919"
}

Dimić, I., Cvijović-Alagić, I., Hohenwarter, A., Pippan, R., Kojić, V., Bajat, J.,& Rakin, M.. (2018). Electrochemical and biocompatibility examinations of high-pressure torsion processed titanium and Ti-13Nb-13Zr alloy. in Journal of Biomedical Materials Research Part B-Applied Biomaterials
Wiley, Hoboken., 106(3), 1097-1107.
https://doi.org/10.1002/jbm.b.33919

Dimić I, Cvijović-Alagić I, Hohenwarter A, Pippan R, Kojić V, Bajat J, Rakin M. Electrochemical and biocompatibility examinations of high-pressure torsion processed titanium and Ti-13Nb-13Zr alloy. in Journal of Biomedical Materials Research Part B-Applied Biomaterials. 2018;106(3):1097-1107.
doi:10.1002/jbm.b.33919 .

Dimić, Ivana, Cvijović-Alagić, Ivana, Hohenwarter, Anton, Pippan, Reinhard, Kojić, Vesna, Bajat, Jelena, Rakin, Marko, "Electrochemical and biocompatibility examinations of high-pressure torsion processed titanium and Ti-13Nb-13Zr alloy" in Journal of Biomedical Materials Research Part B-Applied Biomaterials, 106, no. 3 (2018):1097-1107,
https://doi.org/10.1002/jbm.b.33919 . .

TY  - JOUR
AU  - Dimić, Ivana
AU  - Cvijović-Alagić, Ivana
AU  - Voelker, Bernhard
AU  - Hohenwarter, Anton
AU  - Pippan, Reinhard
AU  - Veljović, Đorđe
AU  - Rakin, Marko
AU  - Bugarski, Branko
PY  - 2016
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3446
AB  - Significant enhancement of mechanical properties of metallic biomaterials can be achieved by grain refinement obtained by severe plastic deformation. The purpose of this study was to determine metallic ion release from commercially pure titanium (CPTi) and Ti-13Nb-13Zr alloy processed by high pressure torsion (HPT). The materials microstructures, in the initial state and after HPT deformation, were examined by scanning and transmission electron microscopy. The microhardness was determined along the radius of the disc-shaped samples of ultrafine-grained (UFG) CPTi and Ti-13Nb-13Zr alloy in order to evaluate homogeneity of HPT-processed materials. The quantities of released ions were determined using inductively coupled plasma-mass spectrophotometer for samples immersed in artificial saliva at 37 degrees C for 7 days. Also, the effect of artificial saliva pH value on metallic ion release was estimated. Obtained results revealed that the quantities of released ions from UFG CPTi and Ti-13Nb-13Zr alloy obtained by HPT process were higher than the quantities of released ions from CPTi and Ti-13Nb-13Zr alloy produced by traditional casting. This behavior can be explained by the fact that metallic ions are easily released from microstructure with smaller grains achieved by HPT process.
PB  - Elsevier Sci Ltd, Oxford
T2  - Materials & Design
T1  - Microstructure and metallic ion release of pure titanium and Ti-13Nb-13Zr alloy processed by high pressure torsion
EP  - 347
SP  - 340
VL  - 91
DO  - 10.1016/j.matdes.2015.11.088
ER  - 

@article{
author = "Dimić, Ivana and Cvijović-Alagić, Ivana and Voelker, Bernhard and Hohenwarter, Anton and Pippan, Reinhard and Veljović, Đorđe and Rakin, Marko and Bugarski, Branko",
year = "2016",
abstract = "Significant enhancement of mechanical properties of metallic biomaterials can be achieved by grain refinement obtained by severe plastic deformation. The purpose of this study was to determine metallic ion release from commercially pure titanium (CPTi) and Ti-13Nb-13Zr alloy processed by high pressure torsion (HPT). The materials microstructures, in the initial state and after HPT deformation, were examined by scanning and transmission electron microscopy. The microhardness was determined along the radius of the disc-shaped samples of ultrafine-grained (UFG) CPTi and Ti-13Nb-13Zr alloy in order to evaluate homogeneity of HPT-processed materials. The quantities of released ions were determined using inductively coupled plasma-mass spectrophotometer for samples immersed in artificial saliva at 37 degrees C for 7 days. Also, the effect of artificial saliva pH value on metallic ion release was estimated. Obtained results revealed that the quantities of released ions from UFG CPTi and Ti-13Nb-13Zr alloy obtained by HPT process were higher than the quantities of released ions from CPTi and Ti-13Nb-13Zr alloy produced by traditional casting. This behavior can be explained by the fact that metallic ions are easily released from microstructure with smaller grains achieved by HPT process.",
publisher = "Elsevier Sci Ltd, Oxford",
journal = "Materials & Design",
title = "Microstructure and metallic ion release of pure titanium and Ti-13Nb-13Zr alloy processed by high pressure torsion",
pages = "347-340",
volume = "91",
doi = "10.1016/j.matdes.2015.11.088"
}

Dimić, I., Cvijović-Alagić, I., Voelker, B., Hohenwarter, A., Pippan, R., Veljović, Đ., Rakin, M.,& Bugarski, B.. (2016). Microstructure and metallic ion release of pure titanium and Ti-13Nb-13Zr alloy processed by high pressure torsion. in Materials & Design
Elsevier Sci Ltd, Oxford., 91, 340-347.
https://doi.org/10.1016/j.matdes.2015.11.088

Dimić I, Cvijović-Alagić I, Voelker B, Hohenwarter A, Pippan R, Veljović Đ, Rakin M, Bugarski B. Microstructure and metallic ion release of pure titanium and Ti-13Nb-13Zr alloy processed by high pressure torsion. in Materials & Design. 2016;91:340-347.
doi:10.1016/j.matdes.2015.11.088 .

Dimić, Ivana, Cvijović-Alagić, Ivana, Voelker, Bernhard, Hohenwarter, Anton, Pippan, Reinhard, Veljović, Đorđe, Rakin, Marko, Bugarski, Branko, "Microstructure and metallic ion release of pure titanium and Ti-13Nb-13Zr alloy processed by high pressure torsion" in Materials & Design, 91 (2016):340-347,
https://doi.org/10.1016/j.matdes.2015.11.088 . .