TY  - JOUR
AU  - Mitrović, Branislava
AU  - Jovanović, Milijan
AU  - Lazarević-Macanović, Mirjana
AU  - Janaćković, Đorđe
AU  - Krstić, Nikola
AU  - Stojanović, Mirjana
AU  - Mirilović, Milorad
PY  - 2015
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/2999
AB  - The use of phosphate mineral products in animal nutrition, as a major source of phosphor and calcium, can lead to uranium entering the food chain. The aim of the present study was to determine the protective effect of natural sepiolite and sepiolite treated with acid for broilers after oral intake of uranium. The broilers were contaminated for 7 days with 25 mg/uranyl nitrate per day. Two different adsorbents (natural sepiolite and sepiolite treated with acid) were given via gastric tube immediately after the oral administration of uranium. Natural sepiolite reduced uranium distribution by 57 % in kidney, 80 % in liver, 42 % in brain, and 56 % in muscle. A lower protective effect was observed after the administration of sepiolite treated with acid, resulting in significant damage of intestinal villi in the form of shortening, fragmentation, and necrosis, and histopathological lesions on kidney in the form of edema and abruption of epithelial cells in tubules. When broilers received only sepiolite treated with acid (no uranyl nitrate), shortening of intestinal villi occurred. Kidney injuries were evident when uranium concentrations in kidney were 0.88 and 1.25 A mu g/g dry weight. It is concluded that adding of natural sepiolite to the diets of broilers can reduce uranium distribution in organs by significant amount without adverse side effects.
PB  - Springer, New York
T2  - Radiation and Environmental Biophysics
T1  - Efficiency of sepiolite in broilers diet as uranium adsorbent
EP  - 224
IS  - 2
SP  - 217
VL  - 54
DO  - 10.1007/s00411-015-0589-2
ER  - 

@article{
author = "Mitrović, Branislava and Jovanović, Milijan and Lazarević-Macanović, Mirjana and Janaćković, Đorđe and Krstić, Nikola and Stojanović, Mirjana and Mirilović, Milorad",
year = "2015",
abstract = "The use of phosphate mineral products in animal nutrition, as a major source of phosphor and calcium, can lead to uranium entering the food chain. The aim of the present study was to determine the protective effect of natural sepiolite and sepiolite treated with acid for broilers after oral intake of uranium. The broilers were contaminated for 7 days with 25 mg/uranyl nitrate per day. Two different adsorbents (natural sepiolite and sepiolite treated with acid) were given via gastric tube immediately after the oral administration of uranium. Natural sepiolite reduced uranium distribution by 57 % in kidney, 80 % in liver, 42 % in brain, and 56 % in muscle. A lower protective effect was observed after the administration of sepiolite treated with acid, resulting in significant damage of intestinal villi in the form of shortening, fragmentation, and necrosis, and histopathological lesions on kidney in the form of edema and abruption of epithelial cells in tubules. When broilers received only sepiolite treated with acid (no uranyl nitrate), shortening of intestinal villi occurred. Kidney injuries were evident when uranium concentrations in kidney were 0.88 and 1.25 A mu g/g dry weight. It is concluded that adding of natural sepiolite to the diets of broilers can reduce uranium distribution in organs by significant amount without adverse side effects.",
publisher = "Springer, New York",
journal = "Radiation and Environmental Biophysics",
title = "Efficiency of sepiolite in broilers diet as uranium adsorbent",
pages = "224-217",
number = "2",
volume = "54",
doi = "10.1007/s00411-015-0589-2"
}

Mitrović, B., Jovanović, M., Lazarević-Macanović, M., Janaćković, Đ., Krstić, N., Stojanović, M.,& Mirilović, M.. (2015). Efficiency of sepiolite in broilers diet as uranium adsorbent. in Radiation and Environmental Biophysics
Springer, New York., 54(2), 217-224.
https://doi.org/10.1007/s00411-015-0589-2

Mitrović B, Jovanović M, Lazarević-Macanović M, Janaćković Đ, Krstić N, Stojanović M, Mirilović M. Efficiency of sepiolite in broilers diet as uranium adsorbent. in Radiation and Environmental Biophysics. 2015;54(2):217-224.
doi:10.1007/s00411-015-0589-2 .

Mitrović, Branislava, Jovanović, Milijan, Lazarević-Macanović, Mirjana, Janaćković, Đorđe, Krstić, Nikola, Stojanović, Mirjana, Mirilović, Milorad, "Efficiency of sepiolite in broilers diet as uranium adsorbent" in Radiation and Environmental Biophysics, 54, no. 2 (2015):217-224,
https://doi.org/10.1007/s00411-015-0589-2 . .