TY  - JOUR
AU  - Milovanović, Stoja
AU  - Djuris, Jelena
AU  - Dapčević, Aleksandra
AU  - Lučić-Škorić, Marija
AU  - Medarevic, Đorđe
AU  - Pavlovic, Stefan M.
AU  - Ibric, Svetlana
PY  - 2021
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4959
AB  - This study investigates pharmaceutical polymers (Soluplus((R)), HPMCAS, and Eudragit((R)) E100) and supercritical CO2-assisted process for preparation of floating valsartan delivery systems. Tested process (at pressure of 30 MPa and temperature of 100 degrees C during 2 h) enabled preparation of stable porous valsartan formulations which was confirmed with FESEM and mercury intrusion porosimetry analysis. The bulk density of obtained formulations was lower than 550 kg/m(3). FTIR, DSC, and PXRD analysis indicated that there was no chemical interaction between the drug and polymers and that amorphous solid dispersions were obtained. Formulations with Soluplus((R)) and HPMCAS retained its buoyancy in 0.1 M HCl for longer than 24 h, while formulation with Eudragit((R)) E100 retained its buoyancy up to 2 h. Controlled valsartan release was influenced by solubility of polymers in the tested release medium, which was confirmed by UV/VIS spectroscopy. The obtained results provided framework for further development of floating drug delivery system using an environmental friendly process.
T2  - Journal of Polymer Research
T1  - Preparation of floating polymer-valsartan delivery systems using supercritical CO2
IS  - 3
VL  - 28
DO  - 10.1007/s10965-021-02440-1
ER  - 

@article{
author = "Milovanović, Stoja and Djuris, Jelena and Dapčević, Aleksandra and Lučić-Škorić, Marija and Medarevic, Đorđe and Pavlovic, Stefan M. and Ibric, Svetlana",
year = "2021",
abstract = "This study investigates pharmaceutical polymers (Soluplus((R)), HPMCAS, and Eudragit((R)) E100) and supercritical CO2-assisted process for preparation of floating valsartan delivery systems. Tested process (at pressure of 30 MPa and temperature of 100 degrees C during 2 h) enabled preparation of stable porous valsartan formulations which was confirmed with FESEM and mercury intrusion porosimetry analysis. The bulk density of obtained formulations was lower than 550 kg/m(3). FTIR, DSC, and PXRD analysis indicated that there was no chemical interaction between the drug and polymers and that amorphous solid dispersions were obtained. Formulations with Soluplus((R)) and HPMCAS retained its buoyancy in 0.1 M HCl for longer than 24 h, while formulation with Eudragit((R)) E100 retained its buoyancy up to 2 h. Controlled valsartan release was influenced by solubility of polymers in the tested release medium, which was confirmed by UV/VIS spectroscopy. The obtained results provided framework for further development of floating drug delivery system using an environmental friendly process.",
journal = "Journal of Polymer Research",
title = "Preparation of floating polymer-valsartan delivery systems using supercritical CO2",
number = "3",
volume = "28",
doi = "10.1007/s10965-021-02440-1"
}

Milovanović, S., Djuris, J., Dapčević, A., Lučić-Škorić, M., Medarevic, Đ., Pavlovic, S. M.,& Ibric, S.. (2021). Preparation of floating polymer-valsartan delivery systems using supercritical CO2. in Journal of Polymer Research, 28(3).
https://doi.org/10.1007/s10965-021-02440-1

Milovanović S, Djuris J, Dapčević A, Lučić-Škorić M, Medarevic Đ, Pavlovic SM, Ibric S. Preparation of floating polymer-valsartan delivery systems using supercritical CO2. in Journal of Polymer Research. 2021;28(3).
doi:10.1007/s10965-021-02440-1 .

Milovanović, Stoja, Djuris, Jelena, Dapčević, Aleksandra, Lučić-Škorić, Marija, Medarevic, Đorđe, Pavlovic, Stefan M., Ibric, Svetlana, "Preparation of floating polymer-valsartan delivery systems using supercritical CO2" in Journal of Polymer Research, 28, no. 3 (2021),
https://doi.org/10.1007/s10965-021-02440-1 . .

TY  - JOUR
AU  - Milovanović, Stoja
AU  - Marković, Darka
AU  - Pantic, Milica
AU  - Pavlovic, Stefan M.
AU  - Knapczyk-Korczak, Joanna
AU  - Stachewicz, Urszula
AU  - Novak, Zoran
PY  - 2021
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4786
AB  - The release of industrial wastewater into the ecosystem prompted our research on the development of an efficient and biodegradable material that can be used for wastewater treatment. We optimized preparation of porous material from poly(lactic acid) (PLA) by variation in solvents and drying methods (air-drying vs. supercritical CO2-drying). In addition, we optimized the method of TiO2 nanoparticles immobilization (in situ vs. ex situ) onto porous PLA. The material properties and functionality were verified by SEM, water displacement, gas adsorption desorption, Hg-intrusion porosimetry, dye degradation, FTIR, TGA/DSC, and water contact angle analysis. We showed that the morphology of PLA material could be controlled by variation in process parameters resulting in porosity from 43% to 73%. The prepared material sustained floatability for longer than 4 weeks and provided complete discoloration of dye C.I. Acid Orange 7 after 240 min of illumination. The high photocatalytic activity was preserved within three repeated cycles.
T2  - Journal of Supercritical Fluids
T1  - Development of advanced floating poly(lactic acid)-based materials for colored wastewater treatment
VL  - 177
DO  - 10.1016/j.supflu.2021.105328
ER  - 

@article{
author = "Milovanović, Stoja and Marković, Darka and Pantic, Milica and Pavlovic, Stefan M. and Knapczyk-Korczak, Joanna and Stachewicz, Urszula and Novak, Zoran",
year = "2021",
abstract = "The release of industrial wastewater into the ecosystem prompted our research on the development of an efficient and biodegradable material that can be used for wastewater treatment. We optimized preparation of porous material from poly(lactic acid) (PLA) by variation in solvents and drying methods (air-drying vs. supercritical CO2-drying). In addition, we optimized the method of TiO2 nanoparticles immobilization (in situ vs. ex situ) onto porous PLA. The material properties and functionality were verified by SEM, water displacement, gas adsorption desorption, Hg-intrusion porosimetry, dye degradation, FTIR, TGA/DSC, and water contact angle analysis. We showed that the morphology of PLA material could be controlled by variation in process parameters resulting in porosity from 43% to 73%. The prepared material sustained floatability for longer than 4 weeks and provided complete discoloration of dye C.I. Acid Orange 7 after 240 min of illumination. The high photocatalytic activity was preserved within three repeated cycles.",
journal = "Journal of Supercritical Fluids",
title = "Development of advanced floating poly(lactic acid)-based materials for colored wastewater treatment",
volume = "177",
doi = "10.1016/j.supflu.2021.105328"
}

Milovanović, S., Marković, D., Pantic, M., Pavlovic, S. M., Knapczyk-Korczak, J., Stachewicz, U.,& Novak, Z.. (2021). Development of advanced floating poly(lactic acid)-based materials for colored wastewater treatment. in Journal of Supercritical Fluids, 177.
https://doi.org/10.1016/j.supflu.2021.105328

Milovanović S, Marković D, Pantic M, Pavlovic SM, Knapczyk-Korczak J, Stachewicz U, Novak Z. Development of advanced floating poly(lactic acid)-based materials for colored wastewater treatment. in Journal of Supercritical Fluids. 2021;177.
doi:10.1016/j.supflu.2021.105328 .

Milovanović, Stoja, Marković, Darka, Pantic, Milica, Pavlovic, Stefan M., Knapczyk-Korczak, Joanna, Stachewicz, Urszula, Novak, Zoran, "Development of advanced floating poly(lactic acid)-based materials for colored wastewater treatment" in Journal of Supercritical Fluids, 177 (2021),
https://doi.org/10.1016/j.supflu.2021.105328 . .

TY  - JOUR
AU  - Pavlovic, Stefan M.
AU  - Marinkovic, Dalibor M.
AU  - Kostic, Milan D.
AU  - Loncarevic, Davor R.
AU  - Mojović, Ljiljana
AU  - Stankovic, Miroslav, V
AU  - Veljkovic, Vlada B.
PY  - 2021
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4971
AB  - Lignite coal fly ash (FA) from a domestic thermal power plant was converted into a pure cancrinite zeolitic material (ZM(FA)) using a novel, custom-made, rotating autoclave reactor system by a short-term alkali activation process. The obtained ZM(FA) was used as catalyst support of calcium oxide as an active component derived from waste chicken eggshells (ES). The ZM(FA) supported calcium oxide catalyst (xCaO/ZM(FA)) was synthesized by means of the ultrasound-assisted method. The influence of different concentrations of dispersed calcium oxide (x = 5-20 wt%) over ZM(FA) and thermal treatment at different temperatures (450-600 degrees C) were studied. The structural and morphological characterization showed that the original cancrinite structure was preserved. The basicity and textural properties indicated the presence of strong active sites in a well-defined pore network suitable for the reactions of bulky organic compounds such as triacylglycerols (TAGs). The highest activity (96.5% of fatty acid methyl esters) in the methanolysis of sunflower oil was achieved with the 20CaO/ZM(FA) catalyst under reaction conditions: temperature of 60 degrees C, methanol/oil molar ratio of 12:1, catalyst concentration of 4 wt%, and reaction time of 2 h. It was found that the optimal calcination temperature of the catalyst precursor was 550 degrees C. At calcination temperatures above 550 degrees C, the melting of the glassy phase became more intense whereby the molten phase partially reacted with calcium oxide forming the catalytically inactive calcium silicate compounds (wollastonite, larnite, etc.). The rate constants of the two tested kinetic models were correlated with the concentrations of active calcium oxide. The MRPD of both models was low indicating their reliability.
T2  - Fuel
T1  - The chicken eggshell calcium oxide ultrasonically dispersed over lignite coal fly ash-based cancrinite zeolite support as a catalyst for biodiesel production
VL  - 289
DO  - 10.1016/j.fuel.2020.119912
ER  - 

@article{
author = "Pavlovic, Stefan M. and Marinkovic, Dalibor M. and Kostic, Milan D. and Loncarevic, Davor R. and Mojović, Ljiljana and Stankovic, Miroslav, V and Veljkovic, Vlada B.",
year = "2021",
abstract = "Lignite coal fly ash (FA) from a domestic thermal power plant was converted into a pure cancrinite zeolitic material (ZM(FA)) using a novel, custom-made, rotating autoclave reactor system by a short-term alkali activation process. The obtained ZM(FA) was used as catalyst support of calcium oxide as an active component derived from waste chicken eggshells (ES). The ZM(FA) supported calcium oxide catalyst (xCaO/ZM(FA)) was synthesized by means of the ultrasound-assisted method. The influence of different concentrations of dispersed calcium oxide (x = 5-20 wt%) over ZM(FA) and thermal treatment at different temperatures (450-600 degrees C) were studied. The structural and morphological characterization showed that the original cancrinite structure was preserved. The basicity and textural properties indicated the presence of strong active sites in a well-defined pore network suitable for the reactions of bulky organic compounds such as triacylglycerols (TAGs). The highest activity (96.5% of fatty acid methyl esters) in the methanolysis of sunflower oil was achieved with the 20CaO/ZM(FA) catalyst under reaction conditions: temperature of 60 degrees C, methanol/oil molar ratio of 12:1, catalyst concentration of 4 wt%, and reaction time of 2 h. It was found that the optimal calcination temperature of the catalyst precursor was 550 degrees C. At calcination temperatures above 550 degrees C, the melting of the glassy phase became more intense whereby the molten phase partially reacted with calcium oxide forming the catalytically inactive calcium silicate compounds (wollastonite, larnite, etc.). The rate constants of the two tested kinetic models were correlated with the concentrations of active calcium oxide. The MRPD of both models was low indicating their reliability.",
journal = "Fuel",
title = "The chicken eggshell calcium oxide ultrasonically dispersed over lignite coal fly ash-based cancrinite zeolite support as a catalyst for biodiesel production",
volume = "289",
doi = "10.1016/j.fuel.2020.119912"
}

Pavlovic, S. M., Marinkovic, D. M., Kostic, M. D., Loncarevic, D. R., Mojović, L., Stankovic, M. V.,& Veljkovic, V. B.. (2021). The chicken eggshell calcium oxide ultrasonically dispersed over lignite coal fly ash-based cancrinite zeolite support as a catalyst for biodiesel production. in Fuel, 289.
https://doi.org/10.1016/j.fuel.2020.119912

Pavlovic SM, Marinkovic DM, Kostic MD, Loncarevic DR, Mojović L, Stankovic MV, Veljkovic VB. The chicken eggshell calcium oxide ultrasonically dispersed over lignite coal fly ash-based cancrinite zeolite support as a catalyst for biodiesel production. in Fuel. 2021;289.
doi:10.1016/j.fuel.2020.119912 .

Pavlovic, Stefan M., Marinkovic, Dalibor M., Kostic, Milan D., Loncarevic, Davor R., Mojović, Ljiljana, Stankovic, Miroslav, V, Veljkovic, Vlada B., "The chicken eggshell calcium oxide ultrasonically dispersed over lignite coal fly ash-based cancrinite zeolite support as a catalyst for biodiesel production" in Fuel, 289 (2021),
https://doi.org/10.1016/j.fuel.2020.119912 . .