TY  - CONF
AU  - Kasalović, Marijana P.
AU  - Lađarević, Jelena
AU  - Božić, Bojan
AU  - Jevtić, Verica V.
AU  - Kaluđerović, Goran N.
AU  - Pantelić, Nebojša Đ.
PY  - 2023
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/6776
AB  - U datom radu opisana je sinteza 2-(4-hidroksi-2-oksohinolinil)propanske kiseline i njenog kompleksa tributilkalaja(IV). Ligand prekursor je dobijen hidrolizom metil-estra sintetisanog u reakciji između 4-hidroksi-2-hinolona i metil-2-bromopropanoata. U reakciji deprotonovanog liganda i ekvimolarne količine Bu3SnCl dobijen je kompleks u obliku belog taloga. Sintetisana jedinjenja su okarakterisana standardnim analitičkim metodama. Ligand prekursor i odgovarajući kompleks tributilkalaja(IV) biće testirani na antitumorsku aktivnost prema raznim tumorskim ćelijskim linijama.
AB  - Synthesis of 2-(4-methyl-2-oxoquinolinyl)propanoic acid and its tributyltin(IV) complex has been performed. The ligand precursor has been obtained by the hydrolysis of methyl ester synthesized in the reaction between 4-hydroxy-2-quinolone and methyl 2- bromopropanoate. In the reaction of deprotonated ligand with equimolar amount of Bu3SnCl, the desired complex was precipitated as a white solid. The synthesized compounds have been characterized using standard analytical methods. The following research of ligand precursor and corresponding tributyltin(IV) complex will be focused on examining their antitumor activity against various cancer cell lines.
PB  - Beograd : Srpsko hemijsko društvo
C3  - Kratki izvodi radova ; Knjiga radova / 59. savetovanje Srpskog hemijskog društva, Novi Sad 1. i 2. jun 2023. godine
T1  - Sinteza i karakterizacija kompleksa tributilkalaja(IV) sa 2-(4- hidroksi-2-oksohinolinil)propanskom kiselinom
T1  - Synthesis and characterization of novel tributyltin(IV) complex with 2-(4-hydroxy-2-oxoquinolinyl)propanoic acid
SP  - 88
UR  - https://hdl.handle.net/21.15107/rcub_technorep_6776
ER  - 

@conference{
author = "Kasalović, Marijana P. and Lađarević, Jelena and Božić, Bojan and Jevtić, Verica V. and Kaluđerović, Goran N. and Pantelić, Nebojša Đ.",
year = "2023",
abstract = "U datom radu opisana je sinteza 2-(4-hidroksi-2-oksohinolinil)propanske kiseline i njenog kompleksa tributilkalaja(IV). Ligand prekursor je dobijen hidrolizom metil-estra sintetisanog u reakciji između 4-hidroksi-2-hinolona i metil-2-bromopropanoata. U reakciji deprotonovanog liganda i ekvimolarne količine Bu3SnCl dobijen je kompleks u obliku belog taloga. Sintetisana jedinjenja su okarakterisana standardnim analitičkim metodama. Ligand prekursor i odgovarajući kompleks tributilkalaja(IV) biće testirani na antitumorsku aktivnost prema raznim tumorskim ćelijskim linijama., Synthesis of 2-(4-methyl-2-oxoquinolinyl)propanoic acid and its tributyltin(IV) complex has been performed. The ligand precursor has been obtained by the hydrolysis of methyl ester synthesized in the reaction between 4-hydroxy-2-quinolone and methyl 2- bromopropanoate. In the reaction of deprotonated ligand with equimolar amount of Bu3SnCl, the desired complex was precipitated as a white solid. The synthesized compounds have been characterized using standard analytical methods. The following research of ligand precursor and corresponding tributyltin(IV) complex will be focused on examining their antitumor activity against various cancer cell lines.",
publisher = "Beograd : Srpsko hemijsko društvo",
journal = "Kratki izvodi radova ; Knjiga radova / 59. savetovanje Srpskog hemijskog društva, Novi Sad 1. i 2. jun 2023. godine",
title = "Sinteza i karakterizacija kompleksa tributilkalaja(IV) sa 2-(4- hidroksi-2-oksohinolinil)propanskom kiselinom, Synthesis and characterization of novel tributyltin(IV) complex with 2-(4-hydroxy-2-oxoquinolinyl)propanoic acid",
pages = "88",
url = "https://hdl.handle.net/21.15107/rcub_technorep_6776"
}

Kasalović, M. P., Lađarević, J., Božić, B., Jevtić, V. V., Kaluđerović, G. N.,& Pantelić, N. Đ.. (2023). Sinteza i karakterizacija kompleksa tributilkalaja(IV) sa 2-(4- hidroksi-2-oksohinolinil)propanskom kiselinom. in Kratki izvodi radova ; Knjiga radova / 59. savetovanje Srpskog hemijskog društva, Novi Sad 1. i 2. jun 2023. godine
Beograd : Srpsko hemijsko društvo., 88.
https://hdl.handle.net/21.15107/rcub_technorep_6776

Kasalović MP, Lađarević J, Božić B, Jevtić VV, Kaluđerović GN, Pantelić NĐ. Sinteza i karakterizacija kompleksa tributilkalaja(IV) sa 2-(4- hidroksi-2-oksohinolinil)propanskom kiselinom. in Kratki izvodi radova ; Knjiga radova / 59. savetovanje Srpskog hemijskog društva, Novi Sad 1. i 2. jun 2023. godine. 2023;:88.
https://hdl.handle.net/21.15107/rcub_technorep_6776 .

Kasalović, Marijana P., Lađarević, Jelena, Božić, Bojan, Jevtić, Verica V., Kaluđerović, Goran N., Pantelić, Nebojša Đ., "Sinteza i karakterizacija kompleksa tributilkalaja(IV) sa 2-(4- hidroksi-2-oksohinolinil)propanskom kiselinom" in Kratki izvodi radova ; Knjiga radova / 59. savetovanje Srpskog hemijskog društva, Novi Sad 1. i 2. jun 2023. godine (2023):88,
https://hdl.handle.net/21.15107/rcub_technorep_6776 .

TY  - CONF
AU  - Radovanović, Lidija
AU  - Lađarević, Jelena
AU  - Božić, Bojan
AU  - Kasalović, Marijana
AU  - Pantelić, Nebojša
AU  - Mijin, Dušan
AU  - Rogan, Jelena
PY  - 2022
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/6724
AB  - 2-Quinolones represent important structural motifs in the numerous biologically active compounds
and naturally occurring alkaloids. Their derivatives show remarkable diversity of pharmalogical
properties such as antibacterial, antifungal, anticancer, antitubercular, anti-inflammatory, and
antihypertensive and play a significant role in the development of the new pharmaceuticals. On the
other hand, propanoic acid derivatives are known for their uniqe terapeutic activity. In an effort to
merge these two structural motifs, two-step synthesis of 3-(4-methyl-2-oxoquinolinyl)propanoic
acid, 1, was performed. The obtained compound was characterized by melting point, FTIR and
NMR spectra. The single crystals of molecule 1, was prepared by slow evaporation from the ethyl
acetate solution. The single crystal X-ray analysis revealed that molecule 1 crystallizes in
monoclinic P21/c space group with Z = 4. The main structural feature is pseudo wavy layer formed
by O–H···O and C–H···O interactions between adjacent molecules, whereas among the layers π···π
stacking and C–H···π interactions were observed, resulting in the formation of supramolecular
network. The main crystallographic data for 1: C13H13NO3, a = 9.2414(4), b = 9.0128(3),
c = 13.6567(6) Å, β = 109.676(4) °, V = 1071.06(8) Å
3
. The refinement based on F
2
(156
parameters) yielded: R1 = 0.0456, wR2 = 0.1287, S = 1.068 for all data, and R1 = 0.0433 for 1765
reflections with I ≥ 2σ(I).
PB  - Banja Luka : University in Banjaluka, Faculty of Technology
C3  - Book of Abstracts / XIV Conference of Chemists, Technologists and Environmentalists of Republic of Srpska, Banja Luka, October 21-22, 2022
T1  - Synthesis, characterization and crystal structure of the 2-quinolone derivative
SP  - 22
UR  - https://hdl.handle.net/21.15107/rcub_technorep_6724
ER  - 

@conference{
author = "Radovanović, Lidija and Lađarević, Jelena and Božić, Bojan and Kasalović, Marijana and Pantelić, Nebojša and Mijin, Dušan and Rogan, Jelena",
year = "2022",
abstract = "2-Quinolones represent important structural motifs in the numerous biologically active compounds
and naturally occurring alkaloids. Their derivatives show remarkable diversity of pharmalogical
properties such as antibacterial, antifungal, anticancer, antitubercular, anti-inflammatory, and
antihypertensive and play a significant role in the development of the new pharmaceuticals. On the
other hand, propanoic acid derivatives are known for their uniqe terapeutic activity. In an effort to
merge these two structural motifs, two-step synthesis of 3-(4-methyl-2-oxoquinolinyl)propanoic
acid, 1, was performed. The obtained compound was characterized by melting point, FTIR and
NMR spectra. The single crystals of molecule 1, was prepared by slow evaporation from the ethyl
acetate solution. The single crystal X-ray analysis revealed that molecule 1 crystallizes in
monoclinic P21/c space group with Z = 4. The main structural feature is pseudo wavy layer formed
by O–H···O and C–H···O interactions between adjacent molecules, whereas among the layers π···π
stacking and C–H···π interactions were observed, resulting in the formation of supramolecular
network. The main crystallographic data for 1: C13H13NO3, a = 9.2414(4), b = 9.0128(3),
c = 13.6567(6) Å, β = 109.676(4) °, V = 1071.06(8) Å
3
. The refinement based on F
2
(156
parameters) yielded: R1 = 0.0456, wR2 = 0.1287, S = 1.068 for all data, and R1 = 0.0433 for 1765
reflections with I ≥ 2σ(I).",
publisher = "Banja Luka : University in Banjaluka, Faculty of Technology",
journal = "Book of Abstracts / XIV Conference of Chemists, Technologists and Environmentalists of Republic of Srpska, Banja Luka, October 21-22, 2022",
title = "Synthesis, characterization and crystal structure of the 2-quinolone derivative",
pages = "22",
url = "https://hdl.handle.net/21.15107/rcub_technorep_6724"
}

Radovanović, L., Lađarević, J., Božić, B., Kasalović, M., Pantelić, N., Mijin, D.,& Rogan, J.. (2022). Synthesis, characterization and crystal structure of the 2-quinolone derivative. in Book of Abstracts / XIV Conference of Chemists, Technologists and Environmentalists of Republic of Srpska, Banja Luka, October 21-22, 2022
Banja Luka : University in Banjaluka, Faculty of Technology., 22.
https://hdl.handle.net/21.15107/rcub_technorep_6724

Radovanović L, Lađarević J, Božić B, Kasalović M, Pantelić N, Mijin D, Rogan J. Synthesis, characterization and crystal structure of the 2-quinolone derivative. in Book of Abstracts / XIV Conference of Chemists, Technologists and Environmentalists of Republic of Srpska, Banja Luka, October 21-22, 2022. 2022;:22.
https://hdl.handle.net/21.15107/rcub_technorep_6724 .

Radovanović, Lidija, Lađarević, Jelena, Božić, Bojan, Kasalović, Marijana, Pantelić, Nebojša, Mijin, Dušan, Rogan, Jelena, "Synthesis, characterization and crystal structure of the 2-quinolone derivative" in Book of Abstracts / XIV Conference of Chemists, Technologists and Environmentalists of Republic of Srpska, Banja Luka, October 21-22, 2022 (2022):22,
https://hdl.handle.net/21.15107/rcub_technorep_6724 .