TY  - CONF
AU  - Gvozdić, Eleonora
AU  - Matić Bujagić, Ivana
AU  - Tolić Stojadinović, Ljiljana
AU  - Grujić, Svetlana
PY  - 2018
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/5945
AB  - After decades of using artificial sweeteners in the food and pharmaceutical industry, their ubiquitous presence in the environment has been determined 1,2. These substances are recognized as emerging pollutants due to limited data on their occurrence, environmental fate and ecotoxicity. Prior to analysis of artificial sweeteners at trace levels in water samples, it is necessary to isolate and concentrate analytes and clean-up the obtained extracts. In this paper, the optimization of the preparation method for the determination of saccharin, sucralose and neotame in water by solid-phase extraction (SPE) was performed. The extracts were analyzed by liquid chromatography–tandem mass spectrometry (LC–MS/MS). In the SPE optimization, the following parameters were tested: the sorbent type, the pH value and the volume of water sample and the elution solvent. The suitability of anion-exchange, polymeric, C18 and carbon sorbents for the extraction of selected sweeteners was assessed. The results showed that the highest recoveries were obtained using polymeric Oasis HLB cartridges, with copolymer poly(divinylbenzene-co-N-vinylpyrrolidone). Furthermore, it was determined that the pH value of water sample was crucial for extraction efficiency. For all three artificial sweeteners, the optimal pH value of the sample was 3. Finally, the sample volume of 100 ml ensured a high preconcentration factor without the sorbent breakthrough, and methanol was selected as the elution solvent.
PB  - Beograd : Srpsko hemijsko društvo
C3  - Kratki izvodi radova / Šesta konferencija mladih hemičara Srbije, Beograd, 27. oktobar 2018
T1  - Optimization of solid-phase extraction for analysis of artificial sweeteners in water
SP  - 33
UR  - https://hdl.handle.net/21.15107/rcub_technorep_5945
ER  - 

@conference{
author = "Gvozdić, Eleonora and Matić Bujagić, Ivana and Tolić Stojadinović, Ljiljana and Grujić, Svetlana",
year = "2018",
abstract = "After decades of using artificial sweeteners in the food and pharmaceutical industry, their ubiquitous presence in the environment has been determined 1,2. These substances are recognized as emerging pollutants due to limited data on their occurrence, environmental fate and ecotoxicity. Prior to analysis of artificial sweeteners at trace levels in water samples, it is necessary to isolate and concentrate analytes and clean-up the obtained extracts. In this paper, the optimization of the preparation method for the determination of saccharin, sucralose and neotame in water by solid-phase extraction (SPE) was performed. The extracts were analyzed by liquid chromatography–tandem mass spectrometry (LC–MS/MS). In the SPE optimization, the following parameters were tested: the sorbent type, the pH value and the volume of water sample and the elution solvent. The suitability of anion-exchange, polymeric, C18 and carbon sorbents for the extraction of selected sweeteners was assessed. The results showed that the highest recoveries were obtained using polymeric Oasis HLB cartridges, with copolymer poly(divinylbenzene-co-N-vinylpyrrolidone). Furthermore, it was determined that the pH value of water sample was crucial for extraction efficiency. For all three artificial sweeteners, the optimal pH value of the sample was 3. Finally, the sample volume of 100 ml ensured a high preconcentration factor without the sorbent breakthrough, and methanol was selected as the elution solvent.",
publisher = "Beograd : Srpsko hemijsko društvo",
journal = "Kratki izvodi radova / Šesta konferencija mladih hemičara Srbije, Beograd, 27. oktobar 2018",
title = "Optimization of solid-phase extraction for analysis of artificial sweeteners in water",
pages = "33",
url = "https://hdl.handle.net/21.15107/rcub_technorep_5945"
}

Gvozdić, E., Matić Bujagić, I., Tolić Stojadinović, L.,& Grujić, S.. (2018). Optimization of solid-phase extraction for analysis of artificial sweeteners in water. in Kratki izvodi radova / Šesta konferencija mladih hemičara Srbije, Beograd, 27. oktobar 2018
Beograd : Srpsko hemijsko društvo., 33.
https://hdl.handle.net/21.15107/rcub_technorep_5945

Gvozdić E, Matić Bujagić I, Tolić Stojadinović L, Grujić S. Optimization of solid-phase extraction for analysis of artificial sweeteners in water. in Kratki izvodi radova / Šesta konferencija mladih hemičara Srbije, Beograd, 27. oktobar 2018. 2018;:33.
https://hdl.handle.net/21.15107/rcub_technorep_5945 .

Gvozdić, Eleonora, Matić Bujagić, Ivana, Tolić Stojadinović, Ljiljana, Grujić, Svetlana, "Optimization of solid-phase extraction for analysis of artificial sweeteners in water" in Kratki izvodi radova / Šesta konferencija mladih hemičara Srbije, Beograd, 27. oktobar 2018 (2018):33,
https://hdl.handle.net/21.15107/rcub_technorep_5945 .