TY  - JOUR
AU  - Barjaktarević, Dragana
AU  - Đokić, Veljko
AU  - Damnjanović, Ivana D.
AU  - Rakin, Marko
PY  - 2018
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3916
AB  - Implant surface properties define the interaction of the implant with the surrounding tissue. To obtained advanced biological, mechanical and physical properties, metallic implants are often exposed to different kinds of surface modification. The electrochemical anodization process is an efficient method for nanostructured surface modification, which leads to the formation of nanotubular oxide layers on metallic surfaces. These obtained layers could be applied in biomedicine due to their chemical stability, biocompatibility and non-toxic nature in the human body. As a part of different kinds of medical implants such as dental implants, artificial hip joints, bone plates, screws, spinal fixation devices or stents, an oxide layer significantly increases cells adhesion and plays a significant role in improving the rate of osseointegration. However, an important topic in research of implants with a nanotubular oxide layer is integrity during fixation and exploitation and possible damage initiation and development. This review article aims to present the application of nanotubular oxide layers in biomedicine and to explain their influence on the biocompatibility and osseointegration of medical implants. Influence of the layers properties, such as roughness or contact angle, and the influence of their morphology on biocompatibility and osseointegration, as well as the influence of fixation and exploitation on the damage of the nanotubular oxide layer, are considered.
PB  - Savez inženjera metalurgije Srbije, Beograd
T2  - Metallurgical & Materials Engineering
T1  - Nanotubular oxide layers formed on the ti-based implants surfaces-application and possible damages: a review
EP  - 259
IS  - 4
SP  - 243
VL  - 24
DO  - 10.30544/401
ER  - 

@article{
author = "Barjaktarević, Dragana and Đokić, Veljko and Damnjanović, Ivana D. and Rakin, Marko",
year = "2018",
abstract = "Implant surface properties define the interaction of the implant with the surrounding tissue. To obtained advanced biological, mechanical and physical properties, metallic implants are often exposed to different kinds of surface modification. The electrochemical anodization process is an efficient method for nanostructured surface modification, which leads to the formation of nanotubular oxide layers on metallic surfaces. These obtained layers could be applied in biomedicine due to their chemical stability, biocompatibility and non-toxic nature in the human body. As a part of different kinds of medical implants such as dental implants, artificial hip joints, bone plates, screws, spinal fixation devices or stents, an oxide layer significantly increases cells adhesion and plays a significant role in improving the rate of osseointegration. However, an important topic in research of implants with a nanotubular oxide layer is integrity during fixation and exploitation and possible damage initiation and development. This review article aims to present the application of nanotubular oxide layers in biomedicine and to explain their influence on the biocompatibility and osseointegration of medical implants. Influence of the layers properties, such as roughness or contact angle, and the influence of their morphology on biocompatibility and osseointegration, as well as the influence of fixation and exploitation on the damage of the nanotubular oxide layer, are considered.",
publisher = "Savez inženjera metalurgije Srbije, Beograd",
journal = "Metallurgical & Materials Engineering",
title = "Nanotubular oxide layers formed on the ti-based implants surfaces-application and possible damages: a review",
pages = "259-243",
number = "4",
volume = "24",
doi = "10.30544/401"
}

Barjaktarević, D., Đokić, V., Damnjanović, I. D.,& Rakin, M.. (2018). Nanotubular oxide layers formed on the ti-based implants surfaces-application and possible damages: a review. in Metallurgical & Materials Engineering
Savez inženjera metalurgije Srbije, Beograd., 24(4), 243-259.
https://doi.org/10.30544/401

Barjaktarević D, Đokić V, Damnjanović ID, Rakin M. Nanotubular oxide layers formed on the ti-based implants surfaces-application and possible damages: a review. in Metallurgical & Materials Engineering. 2018;24(4):243-259.
doi:10.30544/401 .

Barjaktarević, Dragana, Đokić, Veljko, Damnjanović, Ivana D., Rakin, Marko, "Nanotubular oxide layers formed on the ti-based implants surfaces-application and possible damages: a review" in Metallurgical & Materials Engineering, 24, no. 4 (2018):243-259,
https://doi.org/10.30544/401 . .

TY  - JOUR
AU  - Obradović, Nataša
AU  - Krunić, Tanja
AU  - Damnjanović, Ivana D.
AU  - Vukašinović-Sekulić, Maja
AU  - Rakin, Marica
AU  - Rakin, Marko
AU  - Bugarski, Branko
PY  - 2015
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/2907
AB  - Biopolymer carriers are widely used for immobilization of the bioactive compounds and different type of the cells. The aim of this study was to analyze influence of whey proteins addition on mechanical strength of Ca-alginate beads and survival of probiotic bacteria during the whey fermentation process. Mechanical stability of beads was analyzed up to 30% of bead's deformation using compression method between two flat plates. The fermentation was carried out with probiotic starter culture ABY-6 until pH=4.6. The results indicate that the addition of whey proteins in alginate solution increases strength of the beads after fermentation in comparison with alginate beads without proteins and extends the shelf life of products through improving the viability of probiotics.
AB  - Biopolimerni nosači su najčešće korišćenih nosači za imobilizaciju bioaktivnih jedinjenja i različite vrste ćelija. Cilj ovog istraživanja je bila analiza uticaja dodatka proteina surutke na mehaničku čvrstoću kalcijum alginatnih čestica i preživljavanje probiotskih bakterija tokom procesa fermentacije surutke. Mehanička stabilnost nosača je analizirana do 30% deformacije čestica metodom kompresije između dve ravne ploče. Fermentacija se odvijala pomoću probiotiske starter kulture ABY-6 do vrednosti pH = 4.6. Rezultati ukazuju da dodatak proteina surutke u alginatni rastvor povećava čvsrtoću čestica nakon fermentacije u poređenju sa alginatnim česticama bez proteina i produžava rok trajanja proizvoda kroz unapređenje preživljavanja probiotskih bakterija .
PB  - Savez inženjera i tehničara Srbije, Beograd
T2  - Tehnika
T1  - Influence of whey proteins addition on mechanical stability of biopolymer beads with immobilized probiotics
T1  - Uticaj dodatka proteina surutke na mehaničku stabilnost biopolimernih nosača sa imobilisanim probioticima
EP  - 400
IS  - 3
SP  - 397
VL  - 70
DO  - 10.5937/tehnika1503397O
ER  - 

@article{
author = "Obradović, Nataša and Krunić, Tanja and Damnjanović, Ivana D. and Vukašinović-Sekulić, Maja and Rakin, Marica and Rakin, Marko and Bugarski, Branko",
year = "2015",
abstract = "Biopolymer carriers are widely used for immobilization of the bioactive compounds and different type of the cells. The aim of this study was to analyze influence of whey proteins addition on mechanical strength of Ca-alginate beads and survival of probiotic bacteria during the whey fermentation process. Mechanical stability of beads was analyzed up to 30% of bead's deformation using compression method between two flat plates. The fermentation was carried out with probiotic starter culture ABY-6 until pH=4.6. The results indicate that the addition of whey proteins in alginate solution increases strength of the beads after fermentation in comparison with alginate beads without proteins and extends the shelf life of products through improving the viability of probiotics., Biopolimerni nosači su najčešće korišćenih nosači za imobilizaciju bioaktivnih jedinjenja i različite vrste ćelija. Cilj ovog istraživanja je bila analiza uticaja dodatka proteina surutke na mehaničku čvrstoću kalcijum alginatnih čestica i preživljavanje probiotskih bakterija tokom procesa fermentacije surutke. Mehanička stabilnost nosača je analizirana do 30% deformacije čestica metodom kompresije između dve ravne ploče. Fermentacija se odvijala pomoću probiotiske starter kulture ABY-6 do vrednosti pH = 4.6. Rezultati ukazuju da dodatak proteina surutke u alginatni rastvor povećava čvsrtoću čestica nakon fermentacije u poređenju sa alginatnim česticama bez proteina i produžava rok trajanja proizvoda kroz unapređenje preživljavanja probiotskih bakterija .",
publisher = "Savez inženjera i tehničara Srbije, Beograd",
journal = "Tehnika",
title = "Influence of whey proteins addition on mechanical stability of biopolymer beads with immobilized probiotics, Uticaj dodatka proteina surutke na mehaničku stabilnost biopolimernih nosača sa imobilisanim probioticima",
pages = "400-397",
number = "3",
volume = "70",
doi = "10.5937/tehnika1503397O"
}

Obradović, N., Krunić, T., Damnjanović, I. D., Vukašinović-Sekulić, M., Rakin, M., Rakin, M.,& Bugarski, B.. (2015). Influence of whey proteins addition on mechanical stability of biopolymer beads with immobilized probiotics. in Tehnika
Savez inženjera i tehničara Srbije, Beograd., 70(3), 397-400.
https://doi.org/10.5937/tehnika1503397O

Obradović N, Krunić T, Damnjanović ID, Vukašinović-Sekulić M, Rakin M, Rakin M, Bugarski B. Influence of whey proteins addition on mechanical stability of biopolymer beads with immobilized probiotics. in Tehnika. 2015;70(3):397-400.
doi:10.5937/tehnika1503397O .

Obradović, Nataša, Krunić, Tanja, Damnjanović, Ivana D., Vukašinović-Sekulić, Maja, Rakin, Marica, Rakin, Marko, Bugarski, Branko, "Influence of whey proteins addition on mechanical stability of biopolymer beads with immobilized probiotics" in Tehnika, 70, no. 3 (2015):397-400,
https://doi.org/10.5937/tehnika1503397O . .