TY  - CHAP
AU  - Mihajlović, Dragana
AU  - Rakin, Marko
AU  - Hohenwarter, Anton
AU  - Veljović, Đorđe
AU  - Kojić, Vesna
AU  - Đokić, Veljko
PY  - 2024
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/7147
AB  - Primary implant stability after implantation is in relation with its good mechanical contact with the touching tissue. Adequate integration of the implant with the bone tissue is necessary to provide safety and efficiency of the implant over its life. Generally, two surface properties are the most important facts for tissue response to the implant: the surface topography and chemical composition. Compared to a smooth implant surface, a controlled rough surface provides more surface area for integration with the surrounding tissues and allows successful implant ingrowth into the tissues. It was found that the nanostructured modification of the titanium surface on the level of nano-sized pores influences the adhesion, spreading and growing of osteoblastic cells. There are many methods for nanostructure modification of biomedical alloy surfaces, but one of the common techniques is electrochemical anodization (anodic oxidation). Electrochemical anodization is a method that leads to the creation of a nanotubular oxide film on the material surface. The advantage of anodic oxidation is the possibility of controlling the nanostructured morphology of the surface and dimensions of nanotubes, such as diameter, length, wall thickness and shape of nanotubes through variation of the solution, pH value, potential or duration of anodic oxidation. 
Surface modification of Ti-13Nb-13Zr alloy in a coarse-grained (as received) and ultrafine-grained state induced by high pressure torsion was conducted using an electrochemical anodization process in a 1 M H3PO4 + NaF electrolyte, for 30, 60, 90 and 120 minutes. Scanning electron microscopy (SEM) was used to analyze the morphology, while atomic force microscopy (AFM) was used to characterize the topography of the modified surface. The results showed that a homogenous nanotubular oxide film consisting of nanotubes could be obtained using the electrochemical anodization treatment, while the roughness of the nanostructured surface increased compared to the bare surface. The aim of the studies given in this chapter is to examine the morphology of the nanostructured surface and estimate in vitro biocompatibility of the above-mentioned titanium alloy after the creation of the nanotubular oxide film. In vitro examinations were performed on mouse fibroblast (L929) and human fibroblast (MRC-5) cell lines. The results showed that the nanotubular oxide film obtained on the coarse-grained Ti-13Nb-13Zr alloy (CG TNZ) and the ultrafine-grained Ti-13Nb-13Zr alloy (UFG TNZ) increased the fractions of surviving cells compared to their counterpart alloy, while the cells had better spreading and adhesion on the nanostructured and bare surfaces of the UFG titanium alloy.
PB  - Hoboken : John Wiley & Sons
PB  - Beverly : Scrivener Publishing LLC
T2  - Mechanical Engineering in Biomedical Application: Bio-3D Printing, Biofluid Mechanics, Implant Design, Biomaterials, Computational Biomechanics, Tissue Mechanics
T1  - The Effect of the Nanostructured Surface Modification on the Morphology and Biocompatibility of Ultrafine-Grained Titanium Alloy for Medical Application
EP  - 150
SP  - 121
DO  - 10.1002/9781394175109.ch5
UR  - https://hdl.handle.net/21.15107/rcub_technorep_7147
ER  - 

@inbook{
author = "Mihajlović, Dragana and Rakin, Marko and Hohenwarter, Anton and Veljović, Đorđe and Kojić, Vesna and Đokić, Veljko",
year = "2024",
abstract = "Primary implant stability after implantation is in relation with its good mechanical contact with the touching tissue. Adequate integration of the implant with the bone tissue is necessary to provide safety and efficiency of the implant over its life. Generally, two surface properties are the most important facts for tissue response to the implant: the surface topography and chemical composition. Compared to a smooth implant surface, a controlled rough surface provides more surface area for integration with the surrounding tissues and allows successful implant ingrowth into the tissues. It was found that the nanostructured modification of the titanium surface on the level of nano-sized pores influences the adhesion, spreading and growing of osteoblastic cells. There are many methods for nanostructure modification of biomedical alloy surfaces, but one of the common techniques is electrochemical anodization (anodic oxidation). Electrochemical anodization is a method that leads to the creation of a nanotubular oxide film on the material surface. The advantage of anodic oxidation is the possibility of controlling the nanostructured morphology of the surface and dimensions of nanotubes, such as diameter, length, wall thickness and shape of nanotubes through variation of the solution, pH value, potential or duration of anodic oxidation. 
Surface modification of Ti-13Nb-13Zr alloy in a coarse-grained (as received) and ultrafine-grained state induced by high pressure torsion was conducted using an electrochemical anodization process in a 1 M H3PO4 + NaF electrolyte, for 30, 60, 90 and 120 minutes. Scanning electron microscopy (SEM) was used to analyze the morphology, while atomic force microscopy (AFM) was used to characterize the topography of the modified surface. The results showed that a homogenous nanotubular oxide film consisting of nanotubes could be obtained using the electrochemical anodization treatment, while the roughness of the nanostructured surface increased compared to the bare surface. The aim of the studies given in this chapter is to examine the morphology of the nanostructured surface and estimate in vitro biocompatibility of the above-mentioned titanium alloy after the creation of the nanotubular oxide film. In vitro examinations were performed on mouse fibroblast (L929) and human fibroblast (MRC-5) cell lines. The results showed that the nanotubular oxide film obtained on the coarse-grained Ti-13Nb-13Zr alloy (CG TNZ) and the ultrafine-grained Ti-13Nb-13Zr alloy (UFG TNZ) increased the fractions of surviving cells compared to their counterpart alloy, while the cells had better spreading and adhesion on the nanostructured and bare surfaces of the UFG titanium alloy.",
publisher = "Hoboken : John Wiley & Sons, Beverly : Scrivener Publishing LLC",
journal = "Mechanical Engineering in Biomedical Application: Bio-3D Printing, Biofluid Mechanics, Implant Design, Biomaterials, Computational Biomechanics, Tissue Mechanics",
booktitle = "The Effect of the Nanostructured Surface Modification on the Morphology and Biocompatibility of Ultrafine-Grained Titanium Alloy for Medical Application",
pages = "150-121",
doi = "10.1002/9781394175109.ch5",
url = "https://hdl.handle.net/21.15107/rcub_technorep_7147"
}

Mihajlović, D., Rakin, M., Hohenwarter, A., Veljović, Đ., Kojić, V.,& Đokić, V.. (2024). The Effect of the Nanostructured Surface Modification on the Morphology and Biocompatibility of Ultrafine-Grained Titanium Alloy for Medical Application. in Mechanical Engineering in Biomedical Application: Bio-3D Printing, Biofluid Mechanics, Implant Design, Biomaterials, Computational Biomechanics, Tissue Mechanics
Hoboken : John Wiley & Sons., 121-150.
https://doi.org/10.1002/9781394175109.ch5
https://hdl.handle.net/21.15107/rcub_technorep_7147

Mihajlović D, Rakin M, Hohenwarter A, Veljović Đ, Kojić V, Đokić V. The Effect of the Nanostructured Surface Modification on the Morphology and Biocompatibility of Ultrafine-Grained Titanium Alloy for Medical Application. in Mechanical Engineering in Biomedical Application: Bio-3D Printing, Biofluid Mechanics, Implant Design, Biomaterials, Computational Biomechanics, Tissue Mechanics. 2024;:121-150.
doi:10.1002/9781394175109.ch5
https://hdl.handle.net/21.15107/rcub_technorep_7147 .

Mihajlović, Dragana, Rakin, Marko, Hohenwarter, Anton, Veljović, Đorđe, Kojić, Vesna, Đokić, Veljko, "The Effect of the Nanostructured Surface Modification on the Morphology and Biocompatibility of Ultrafine-Grained Titanium Alloy for Medical Application" in Mechanical Engineering in Biomedical Application: Bio-3D Printing, Biofluid Mechanics, Implant Design, Biomaterials, Computational Biomechanics, Tissue Mechanics (2024):121-150,
https://doi.org/10.1002/9781394175109.ch5 .,
https://hdl.handle.net/21.15107/rcub_technorep_7147 .

TY  - JOUR
AU  - Jaćimović, Nevena
AU  - Đošić, Marija
AU  - Janković, Ana
AU  - Grujić, Svetlana
AU  - Matić Bujagić, Ivana
AU  - Stojanović, Jovica
AU  - Vukašinović-Sekulić, Maja
AU  - Kojić, Vesna
AU  - Mišković-Stanković, Vesna
PY  - 2023
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/7260
AB  - Biocomposite hydroxyapatite/poly(vinyl alcohol)/chitosan/gentamicin coatings were fabricated on titanium by an electrophoretic deposition process (EPD) from an aqueous suspension using the constant voltage method. Characterization of the deposited coatings was performed by scanning electron micros-copy with field emission (FE-SEM), Fourier transform infrared spectroscopy (FT-IR), and X-ray diffraction (XRD) after immersion in simulated body fluid (SBF) at 37 °C. The concentration of the released gentamicin was determined using high-performance liquid chromatography (HPLC) coupled with a mass spectrometer (MS). The release profile confirmed an initial “burst-release effect” with ~ 30 % of the gen-tamicin released in the first 48 h, which could be of assistance in the prevention of biofilm formation. An-tibacterial activity was proven by the agar diffusion method on Staphylococcus aureus TL and Escherich-ia coli ATCC 25922 bacterial strains. Cytotoxicity was tested by the dye exclusion test (DET) on MRC-5 and L929 fibroblast cell lines, with both coatings expressing nontoxicity. The results showed the high ap-plicability potential of a poly(vinyl alcohol)-based biocomposite coating for medical purposes.
PB  - Society of Chemists and Technologists of Macedonia
T2  - Macedonian Journal of Chemistry and Chemical Engineering
T1  - Single-step, electrophoretically deposited hydroxyapatite/poly(vinyl alcohol)/chitosan/gentamicin coating for biomedical applications
EP  - 262
IS  - 2
SP  - 249
VL  - 42
DO  - 10.20450/mjcce.2023.2775
ER  - 

@article{
author = "Jaćimović, Nevena and Đošić, Marija and Janković, Ana and Grujić, Svetlana and Matić Bujagić, Ivana and Stojanović, Jovica and Vukašinović-Sekulić, Maja and Kojić, Vesna and Mišković-Stanković, Vesna",
year = "2023",
abstract = "Biocomposite hydroxyapatite/poly(vinyl alcohol)/chitosan/gentamicin coatings were fabricated on titanium by an electrophoretic deposition process (EPD) from an aqueous suspension using the constant voltage method. Characterization of the deposited coatings was performed by scanning electron micros-copy with field emission (FE-SEM), Fourier transform infrared spectroscopy (FT-IR), and X-ray diffraction (XRD) after immersion in simulated body fluid (SBF) at 37 °C. The concentration of the released gentamicin was determined using high-performance liquid chromatography (HPLC) coupled with a mass spectrometer (MS). The release profile confirmed an initial “burst-release effect” with ~ 30 % of the gen-tamicin released in the first 48 h, which could be of assistance in the prevention of biofilm formation. An-tibacterial activity was proven by the agar diffusion method on Staphylococcus aureus TL and Escherich-ia coli ATCC 25922 bacterial strains. Cytotoxicity was tested by the dye exclusion test (DET) on MRC-5 and L929 fibroblast cell lines, with both coatings expressing nontoxicity. The results showed the high ap-plicability potential of a poly(vinyl alcohol)-based biocomposite coating for medical purposes.",
publisher = "Society of Chemists and Technologists of Macedonia",
journal = "Macedonian Journal of Chemistry and Chemical Engineering",
title = "Single-step, electrophoretically deposited hydroxyapatite/poly(vinyl alcohol)/chitosan/gentamicin coating for biomedical applications",
pages = "262-249",
number = "2",
volume = "42",
doi = "10.20450/mjcce.2023.2775"
}

Jaćimović, N., Đošić, M., Janković, A., Grujić, S., Matić Bujagić, I., Stojanović, J., Vukašinović-Sekulić, M., Kojić, V.,& Mišković-Stanković, V.. (2023). Single-step, electrophoretically deposited hydroxyapatite/poly(vinyl alcohol)/chitosan/gentamicin coating for biomedical applications. in Macedonian Journal of Chemistry and Chemical Engineering
Society of Chemists and Technologists of Macedonia., 42(2), 249-262.
https://doi.org/10.20450/mjcce.2023.2775

Jaćimović N, Đošić M, Janković A, Grujić S, Matić Bujagić I, Stojanović J, Vukašinović-Sekulić M, Kojić V, Mišković-Stanković V. Single-step, electrophoretically deposited hydroxyapatite/poly(vinyl alcohol)/chitosan/gentamicin coating for biomedical applications. in Macedonian Journal of Chemistry and Chemical Engineering. 2023;42(2):249-262.
doi:10.20450/mjcce.2023.2775 .

Jaćimović, Nevena, Đošić, Marija, Janković, Ana, Grujić, Svetlana, Matić Bujagić, Ivana, Stojanović, Jovica, Vukašinović-Sekulić, Maja, Kojić, Vesna, Mišković-Stanković, Vesna, "Single-step, electrophoretically deposited hydroxyapatite/poly(vinyl alcohol)/chitosan/gentamicin coating for biomedical applications" in Macedonian Journal of Chemistry and Chemical Engineering, 42, no. 2 (2023):249-262,
https://doi.org/10.20450/mjcce.2023.2775 . .

TY  - CONF
AU  - Mišković-Stanković, Vesna
AU  - Nešović, Katarina
AU  - Janković, Ana
AU  - Radetić, Tamara
AU  - Perić-Grujić, Aleksandra
AU  - Vukašinović-Sekulić, Maja
AU  - Kojić, Vesna
AU  - Yop Rhee, Kyong
PY  - 2019
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/7245
AB  - In recent times, polymer-based hydrogel materials have presented themselves as excellent candidates for
new-generation wound dressings with improved properties, such as high sorption ability, good mechanical
properties and low adhesiveness [1]. Additionally, cross linked hydrogel matrices serve as excellent carriers
for controlled release of antibacterial agents, such as silver nanoparticles (Ag/NPs), which are preferred over
conventional antibiotics due to multi-phase mechanism of action and low susceptibility to induce bacterial
resistance [2]. In this work, we aim to produce novel silver/poly(vinyl alcohol)/chitosan (Ag/PVA/CHI)
hydrogels for wound dressing applications. The electrochemical route for AgNPs synthesis provided facile
and green method for the reduction of Ag+
ions inside the hydrogel matrices, without the need to use toxic
chemical reducing agents [3]. The effect of chitosan content on the synthesis yield, antibacterial properties,
swelling and release kinetics was investigated. The formation of AgNPs was confirmed using UV-visible
spectroscopy through the appearance of plasmon resonant peaks at around 400 nm (Figure 1a), whereas
transmission electron microscopy (TEM) proved the incorporation of both single and polycrystalline spherical
AgNPs with diameters of 5-10 nm (Figure 1b). The swelling and silver release kinetics were investigated in
modified phosphate buffer solutions (pH 7.4) at 37 °C to mimic physiological conditions. The obtained
swelling isotherms and release profiles were fitted with different models to obtain kinetic and diffusion
parameters (Figure 1c). The antibacterial activity was evaluated against Staphylococcus aureus TL and
Escherichia coli ATCC 25922 bacterial strains using an in-suspension test, and non-toxicity of both silvercontaining and silver-free hydrogels was proved by MTT cytotoxicity test. The obtained results confirmed
strong potential of Ag/PVA/CHI hydrogels for biomedical applications.
PB  - International Association of Physical Chemists
C3  - Book of abstracts / 7th Regional Symposium on Electrochemistry – South East Europe & 8th Kurt Schwabe Symposium, Split, Croatia, May 27-30, 2019
T1  - Poly(vinyl alcohol)/chitosan hydrogels with electrochemically synthesized silver nanoparticles for wound dressing applications
SP  - 121
UR  - https://hdl.handle.net/21.15107/rcub_technorep_7245
ER  - 

@conference{
author = "Mišković-Stanković, Vesna and Nešović, Katarina and Janković, Ana and Radetić, Tamara and Perić-Grujić, Aleksandra and Vukašinović-Sekulić, Maja and Kojić, Vesna and Yop Rhee, Kyong",
year = "2019",
abstract = "In recent times, polymer-based hydrogel materials have presented themselves as excellent candidates for
new-generation wound dressings with improved properties, such as high sorption ability, good mechanical
properties and low adhesiveness [1]. Additionally, cross linked hydrogel matrices serve as excellent carriers
for controlled release of antibacterial agents, such as silver nanoparticles (Ag/NPs), which are preferred over
conventional antibiotics due to multi-phase mechanism of action and low susceptibility to induce bacterial
resistance [2]. In this work, we aim to produce novel silver/poly(vinyl alcohol)/chitosan (Ag/PVA/CHI)
hydrogels for wound dressing applications. The electrochemical route for AgNPs synthesis provided facile
and green method for the reduction of Ag+
ions inside the hydrogel matrices, without the need to use toxic
chemical reducing agents [3]. The effect of chitosan content on the synthesis yield, antibacterial properties,
swelling and release kinetics was investigated. The formation of AgNPs was confirmed using UV-visible
spectroscopy through the appearance of plasmon resonant peaks at around 400 nm (Figure 1a), whereas
transmission electron microscopy (TEM) proved the incorporation of both single and polycrystalline spherical
AgNPs with diameters of 5-10 nm (Figure 1b). The swelling and silver release kinetics were investigated in
modified phosphate buffer solutions (pH 7.4) at 37 °C to mimic physiological conditions. The obtained
swelling isotherms and release profiles were fitted with different models to obtain kinetic and diffusion
parameters (Figure 1c). The antibacterial activity was evaluated against Staphylococcus aureus TL and
Escherichia coli ATCC 25922 bacterial strains using an in-suspension test, and non-toxicity of both silvercontaining and silver-free hydrogels was proved by MTT cytotoxicity test. The obtained results confirmed
strong potential of Ag/PVA/CHI hydrogels for biomedical applications.",
publisher = "International Association of Physical Chemists",
journal = "Book of abstracts / 7th Regional Symposium on Electrochemistry – South East Europe & 8th Kurt Schwabe Symposium, Split, Croatia, May 27-30, 2019",
title = "Poly(vinyl alcohol)/chitosan hydrogels with electrochemically synthesized silver nanoparticles for wound dressing applications",
pages = "121",
url = "https://hdl.handle.net/21.15107/rcub_technorep_7245"
}

Mišković-Stanković, V., Nešović, K., Janković, A., Radetić, T., Perić-Grujić, A., Vukašinović-Sekulić, M., Kojić, V.,& Yop Rhee, K.. (2019). Poly(vinyl alcohol)/chitosan hydrogels with electrochemically synthesized silver nanoparticles for wound dressing applications. in Book of abstracts / 7th Regional Symposium on Electrochemistry – South East Europe & 8th Kurt Schwabe Symposium, Split, Croatia, May 27-30, 2019
International Association of Physical Chemists., 121.
https://hdl.handle.net/21.15107/rcub_technorep_7245

Mišković-Stanković V, Nešović K, Janković A, Radetić T, Perić-Grujić A, Vukašinović-Sekulić M, Kojić V, Yop Rhee K. Poly(vinyl alcohol)/chitosan hydrogels with electrochemically synthesized silver nanoparticles for wound dressing applications. in Book of abstracts / 7th Regional Symposium on Electrochemistry – South East Europe & 8th Kurt Schwabe Symposium, Split, Croatia, May 27-30, 2019. 2019;:121.
https://hdl.handle.net/21.15107/rcub_technorep_7245 .

Mišković-Stanković, Vesna, Nešović, Katarina, Janković, Ana, Radetić, Tamara, Perić-Grujić, Aleksandra, Vukašinović-Sekulić, Maja, Kojić, Vesna, Yop Rhee, Kyong, "Poly(vinyl alcohol)/chitosan hydrogels with electrochemically synthesized silver nanoparticles for wound dressing applications" in Book of abstracts / 7th Regional Symposium on Electrochemistry – South East Europe & 8th Kurt Schwabe Symposium, Split, Croatia, May 27-30, 2019 (2019):121,
https://hdl.handle.net/21.15107/rcub_technorep_7245 .

TY  - CONF
AU  - Nešović, Katarina
AU  - Janković, Ana
AU  - Radetić, Tamara
AU  - Kojić, Vesna
AU  - Mišković-Stanković, Vesna
PY  - 2019
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/7246
AB  - Nauka i inženjerstvo biomaterijala u poslednje vreme pokazuju sve veću težnju ka
pronalaženju novih materijala za obloge za rane, gde su naročito važna poboljšana svojstva
kao što su apsorpciona moć, mehanička svojstva i niska adhezivnost. Umrežene matrice
hidrogelova su odlični potencijalni nosači za kontrolisano otpuštanje antibakterijskih
agenasa, kao što su nanočestice srebra. Hitozan je posebno interesantna komponenta
obloga za rane, zbog svoje prirodne antibakterijske aktivnosti i sposobnosti stabilizacije
nanočestica. Cilj ovog rada je priprema novih obloga za rane na bazi polivinil-alkohola i
hitozana sa elektrohemijski sintetisanim nanočesticama srebra, u obliku hidrogela. Dobijene
su sferne nanočestice srebra, prečnika oko 5-10 nm, što je potvrđeno UV-vidljivom
spektroskopijom i transmisionom elektronskom mikroskopijom. Bubrenje i otpuštanje
srebra je praćeno u fosfatnom puferu koji imitira fiziološke uslove, dok je antibakterijska
aktivnost potvrđena na bakterijskim sojevima Staphylococcus aureus i Escherichia coli.
Dobijeni netoksični hidrogelovi (što je utvrđeno MTT testom) imaju izuzetan potencijal za
primene kao obloge za rane nove generacije.
AB  - Recently, the biomaterials science and engineering fields have seen a shift towards novel
hydrogel materials, especially for wound dressing applications where improved properties,
such as high sorption ability, good mechanical properties and low adhesiveness are of
utmost importance. The cross linked hydrogel matrices are excellent potential carriers for
controlled release of antibacterial agents, such as silver nanoparticles (AgNPs). Chitosan is
an especially attractive option for wound dressing applications, because of its intrinsic
antibacterial activity and the ability to stabilize AgNPs. The aim of this work is the production
of poly(vinyl alcohol) and chitosan based hydrogel matrices with electrochemically
synthesized AgNPs for wound dressing materials applications. The obtained AgNPs were
spherical with 5-10 nm diameters, as confirmed by UV-visible spectroscopy and
transmission electron microscopy. The swelling and release behaviors of AgNP-embedded
hydrogels were evaluated in phosphate buffer, mimicking physiological environment, and
the antibacterial activity was confirmed against both Staphylococcus aureus and Escherichia
coli. The obtained non-toxic hydrogel materials (as affirmed by MTT test) have excellent
potential to be used as novel antibacterial wound dressings.
PB  - Beograd : Srpsko hemijsko društvo
C3  - Kratki izvodi radova / 56. savetovanje Srpskog hemijskog društva , Niš 7. i 8. juni 2019
T1  - Novi materijali za obloge za rane sa elektrohemijski sintetisanim nanočesticama srebra
T1  - Novel wound dressing materials containing electrochemically synthesized silver nanoparticles
SP  - 27
UR  - https://hdl.handle.net/21.15107/rcub_technorep_7246
ER  - 

@conference{
author = "Nešović, Katarina and Janković, Ana and Radetić, Tamara and Kojić, Vesna and Mišković-Stanković, Vesna",
year = "2019",
abstract = "Nauka i inženjerstvo biomaterijala u poslednje vreme pokazuju sve veću težnju ka
pronalaženju novih materijala za obloge za rane, gde su naročito važna poboljšana svojstva
kao što su apsorpciona moć, mehanička svojstva i niska adhezivnost. Umrežene matrice
hidrogelova su odlični potencijalni nosači za kontrolisano otpuštanje antibakterijskih
agenasa, kao što su nanočestice srebra. Hitozan je posebno interesantna komponenta
obloga za rane, zbog svoje prirodne antibakterijske aktivnosti i sposobnosti stabilizacije
nanočestica. Cilj ovog rada je priprema novih obloga za rane na bazi polivinil-alkohola i
hitozana sa elektrohemijski sintetisanim nanočesticama srebra, u obliku hidrogela. Dobijene
su sferne nanočestice srebra, prečnika oko 5-10 nm, što je potvrđeno UV-vidljivom
spektroskopijom i transmisionom elektronskom mikroskopijom. Bubrenje i otpuštanje
srebra je praćeno u fosfatnom puferu koji imitira fiziološke uslove, dok je antibakterijska
aktivnost potvrđena na bakterijskim sojevima Staphylococcus aureus i Escherichia coli.
Dobijeni netoksični hidrogelovi (što je utvrđeno MTT testom) imaju izuzetan potencijal za
primene kao obloge za rane nove generacije., Recently, the biomaterials science and engineering fields have seen a shift towards novel
hydrogel materials, especially for wound dressing applications where improved properties,
such as high sorption ability, good mechanical properties and low adhesiveness are of
utmost importance. The cross linked hydrogel matrices are excellent potential carriers for
controlled release of antibacterial agents, such as silver nanoparticles (AgNPs). Chitosan is
an especially attractive option for wound dressing applications, because of its intrinsic
antibacterial activity and the ability to stabilize AgNPs. The aim of this work is the production
of poly(vinyl alcohol) and chitosan based hydrogel matrices with electrochemically
synthesized AgNPs for wound dressing materials applications. The obtained AgNPs were
spherical with 5-10 nm diameters, as confirmed by UV-visible spectroscopy and
transmission electron microscopy. The swelling and release behaviors of AgNP-embedded
hydrogels were evaluated in phosphate buffer, mimicking physiological environment, and
the antibacterial activity was confirmed against both Staphylococcus aureus and Escherichia
coli. The obtained non-toxic hydrogel materials (as affirmed by MTT test) have excellent
potential to be used as novel antibacterial wound dressings.",
publisher = "Beograd : Srpsko hemijsko društvo",
journal = "Kratki izvodi radova / 56. savetovanje Srpskog hemijskog društva , Niš 7. i 8. juni 2019",
title = "Novi materijali za obloge za rane sa elektrohemijski sintetisanim nanočesticama srebra, Novel wound dressing materials containing electrochemically synthesized silver nanoparticles",
pages = "27",
url = "https://hdl.handle.net/21.15107/rcub_technorep_7246"
}

Nešović, K., Janković, A., Radetić, T., Kojić, V.,& Mišković-Stanković, V.. (2019). Novi materijali za obloge za rane sa elektrohemijski sintetisanim nanočesticama srebra. in Kratki izvodi radova / 56. savetovanje Srpskog hemijskog društva , Niš 7. i 8. juni 2019
Beograd : Srpsko hemijsko društvo., 27.
https://hdl.handle.net/21.15107/rcub_technorep_7246

Nešović K, Janković A, Radetić T, Kojić V, Mišković-Stanković V. Novi materijali za obloge za rane sa elektrohemijski sintetisanim nanočesticama srebra. in Kratki izvodi radova / 56. savetovanje Srpskog hemijskog društva , Niš 7. i 8. juni 2019. 2019;:27.
https://hdl.handle.net/21.15107/rcub_technorep_7246 .

Nešović, Katarina, Janković, Ana, Radetić, Tamara, Kojić, Vesna, Mišković-Stanković, Vesna, "Novi materijali za obloge za rane sa elektrohemijski sintetisanim nanočesticama srebra" in Kratki izvodi radova / 56. savetovanje Srpskog hemijskog društva , Niš 7. i 8. juni 2019 (2019):27,
https://hdl.handle.net/21.15107/rcub_technorep_7246 .

TY  - CONF
AU  - Veljović, Đorđe
AU  - Radovanović, Željko
AU  - Dimitrijević-Branković, Suzana
AU  - Kojić, Vesna
AU  - Petrović, Rada
AU  - Janaćković, Đorđe
PY  - 2018
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/7162
PB  - Belgrade : Serbian Academy of Sciences and Arts
C3  - Program and Book of Abstracts / First International Conference on Electron Microscopy of Nanostructures ELMINA 2018, August 27-29, 2018, Belgrade, Serbia
T1  - Morphology, biocompatibility and antimicrobial activity of hydroxyapatite simultaneously doped with silver and strontium ions
EP  - 239
SP  - 237
UR  - https://hdl.handle.net/21.15107/rcub_technorep_7162
ER  - 

@conference{
author = "Veljović, Đorđe and Radovanović, Željko and Dimitrijević-Branković, Suzana and Kojić, Vesna and Petrović, Rada and Janaćković, Đorđe",
year = "2018",
publisher = "Belgrade : Serbian Academy of Sciences and Arts",
journal = "Program and Book of Abstracts / First International Conference on Electron Microscopy of Nanostructures ELMINA 2018, August 27-29, 2018, Belgrade, Serbia",
title = "Morphology, biocompatibility and antimicrobial activity of hydroxyapatite simultaneously doped with silver and strontium ions",
pages = "239-237",
url = "https://hdl.handle.net/21.15107/rcub_technorep_7162"
}

Veljović, Đ., Radovanović, Ž., Dimitrijević-Branković, S., Kojić, V., Petrović, R.,& Janaćković, Đ.. (2018). Morphology, biocompatibility and antimicrobial activity of hydroxyapatite simultaneously doped with silver and strontium ions. in Program and Book of Abstracts / First International Conference on Electron Microscopy of Nanostructures ELMINA 2018, August 27-29, 2018, Belgrade, Serbia
Belgrade : Serbian Academy of Sciences and Arts., 237-239.
https://hdl.handle.net/21.15107/rcub_technorep_7162

Veljović Đ, Radovanović Ž, Dimitrijević-Branković S, Kojić V, Petrović R, Janaćković Đ. Morphology, biocompatibility and antimicrobial activity of hydroxyapatite simultaneously doped with silver and strontium ions. in Program and Book of Abstracts / First International Conference on Electron Microscopy of Nanostructures ELMINA 2018, August 27-29, 2018, Belgrade, Serbia. 2018;:237-239.
https://hdl.handle.net/21.15107/rcub_technorep_7162 .

Veljović, Đorđe, Radovanović, Željko, Dimitrijević-Branković, Suzana, Kojić, Vesna, Petrović, Rada, Janaćković, Đorđe, "Morphology, biocompatibility and antimicrobial activity of hydroxyapatite simultaneously doped with silver and strontium ions" in Program and Book of Abstracts / First International Conference on Electron Microscopy of Nanostructures ELMINA 2018, August 27-29, 2018, Belgrade, Serbia (2018):237-239,
https://hdl.handle.net/21.15107/rcub_technorep_7162 .