TY  - CONF
AU  - Veljković, Milica
AU  - Simović, Milica
AU  - Banjanac, Katarina
AU  - Milivojević, Ana
AU  - Ćorović, Marija
AU  - Jaćimovski, Darko
AU  - Bezbradica, Dejan
PY  - 2023
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/6871
AB  - Scientific breakthroughs in research of human microbiota revealed that significant number of
diseases related to modern food intake and sedentary lifestyles are caused by dysbiosis of human
microbiota composition, hence substantial increase in interest for products helping restore this balance
(such as probiotics and prebiotics) within food, cosmetic and health industry was observed. In recent
times, prebiotics have been recognized as attractive products due to their higher stability to processing
and storage conditions, lower susceptibility to interaction with other compounds in more complex
formulation and higher reproducibility of their physiological effects [1]. Consequential rapid growth of
market demand brought challenges for biochemical industry, such as requirements to increase
production capacity and decrease costs by development of more efficient enzymatic processes and
product separation.
Majority of prebiotic compounds are classified as oligosaccharides, which can be obtained
either by enzymatic synthesis from compounds of lower degree of polymerization (DP) - for example:
galacto-oligosaccharides (GOS) from lactose and fructo-oligosaccharides (FOS) from sucrose - or by
enzymatic hydrolysis, for example pectic oligosaccharides (POS) from pectin or xylo-oligosaccharides
(XOS) from xylan [2]. In both cases, membrane separation is efficient tool for product purification,
because OS obtained by synthesis can be separated from lower DP compounds using nanofiltrations,
while those obtained by hydrolysis can be separated from compounds of higher DP using ultrafiltration.
Hence, it can be expected that selection of adequate membrane material, pore dimensions and
downstream processing conditions will have important role in development of novel prebiotic
technologies.
In this study nanofiltration membrane module was applied with a purpose of purification of
FOS obtained in enzymatic synthesis using sucrose as substrate. Two strategies were applied:
• purification of reaction mixture obtained after enzymatic synthesis,
• simultaneous enzymatic synthesis and purification in nanofiltration membrane module.
PB  - TECNALIA
C3  - Proceedings of the 16th International Conference on Catalyst in Membrane Reactors (ICCMR16), October 16-18, 2023, Donostia-San Sebastián, Spain
T1  - Simultaneous enzymatic synthesis and purification of prebiotic fructooligosaccharides in nanofiltration membrane module
EP  - 85
EP  - 
SP  - 84
UR  - https://hdl.handle.net/21.15107/rcub_technorep_6871
ER  - 

@conference{
author = "Veljković, Milica and Simović, Milica and Banjanac, Katarina and Milivojević, Ana and Ćorović, Marija and Jaćimovski, Darko and Bezbradica, Dejan",
year = "2023",
abstract = "Scientific breakthroughs in research of human microbiota revealed that significant number of
diseases related to modern food intake and sedentary lifestyles are caused by dysbiosis of human
microbiota composition, hence substantial increase in interest for products helping restore this balance
(such as probiotics and prebiotics) within food, cosmetic and health industry was observed. In recent
times, prebiotics have been recognized as attractive products due to their higher stability to processing
and storage conditions, lower susceptibility to interaction with other compounds in more complex
formulation and higher reproducibility of their physiological effects [1]. Consequential rapid growth of
market demand brought challenges for biochemical industry, such as requirements to increase
production capacity and decrease costs by development of more efficient enzymatic processes and
product separation.
Majority of prebiotic compounds are classified as oligosaccharides, which can be obtained
either by enzymatic synthesis from compounds of lower degree of polymerization (DP) - for example:
galacto-oligosaccharides (GOS) from lactose and fructo-oligosaccharides (FOS) from sucrose - or by
enzymatic hydrolysis, for example pectic oligosaccharides (POS) from pectin or xylo-oligosaccharides
(XOS) from xylan [2]. In both cases, membrane separation is efficient tool for product purification,
because OS obtained by synthesis can be separated from lower DP compounds using nanofiltrations,
while those obtained by hydrolysis can be separated from compounds of higher DP using ultrafiltration.
Hence, it can be expected that selection of adequate membrane material, pore dimensions and
downstream processing conditions will have important role in development of novel prebiotic
technologies.
In this study nanofiltration membrane module was applied with a purpose of purification of
FOS obtained in enzymatic synthesis using sucrose as substrate. Two strategies were applied:
• purification of reaction mixture obtained after enzymatic synthesis,
• simultaneous enzymatic synthesis and purification in nanofiltration membrane module.",
publisher = "TECNALIA",
journal = "Proceedings of the 16th International Conference on Catalyst in Membrane Reactors (ICCMR16), October 16-18, 2023, Donostia-San Sebastián, Spain",
title = "Simultaneous enzymatic synthesis and purification of prebiotic fructooligosaccharides in nanofiltration membrane module",
pages = "85--84",
url = "https://hdl.handle.net/21.15107/rcub_technorep_6871"
}

Veljković, M., Simović, M., Banjanac, K., Milivojević, A., Ćorović, M., Jaćimovski, D.,& Bezbradica, D.. (2023). Simultaneous enzymatic synthesis and purification of prebiotic fructooligosaccharides in nanofiltration membrane module. in Proceedings of the 16th International Conference on Catalyst in Membrane Reactors (ICCMR16), October 16-18, 2023, Donostia-San Sebastián, Spain
TECNALIA., 84-85.
https://hdl.handle.net/21.15107/rcub_technorep_6871

Veljković M, Simović M, Banjanac K, Milivojević A, Ćorović M, Jaćimovski D, Bezbradica D. Simultaneous enzymatic synthesis and purification of prebiotic fructooligosaccharides in nanofiltration membrane module. in Proceedings of the 16th International Conference on Catalyst in Membrane Reactors (ICCMR16), October 16-18, 2023, Donostia-San Sebastián, Spain. 2023;:84-85.
https://hdl.handle.net/21.15107/rcub_technorep_6871 .

Veljković, Milica, Simović, Milica, Banjanac, Katarina, Milivojević, Ana, Ćorović, Marija, Jaćimovski, Darko, Bezbradica, Dejan, "Simultaneous enzymatic synthesis and purification of prebiotic fructooligosaccharides in nanofiltration membrane module" in Proceedings of the 16th International Conference on Catalyst in Membrane Reactors (ICCMR16), October 16-18, 2023, Donostia-San Sebastián, Spain (2023):84-85,
https://hdl.handle.net/21.15107/rcub_technorep_6871 .

TY  - JOUR
AU  - Jaćimovski, Darko R.
AU  - Brzić, Danica V.
AU  - Garić-Grulović, Radmila V.
AU  - Pjanović, Rada V.
AU  - Đuriš, Mihal M.
AU  - Arsenijević, Zorana L.J.
AU  - Bošković-Vragolović, Nevenka M.
PY  - 2022
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/5231
AB  - In this work the theoretical model for heat transfer from a wall to a liquid-solid fluidized bed by liquid convective mechanism has been proposed and developed. The model is based on thickness of boundary layer and film theory. The key parameter in the model is the distance between two adjacent particles which collide with the wall. According to the proposed model, the liquid convective heat transfer in a fluidized bed is 4 to 5 times more intense than in a single-phase flow. Additionally, the wall-to-bed heat transfer coefficient has been measured experimentally in water–glass particles fluidized bed, for different particle sizes. Comparison of the model prediction with experimental data has shown that size of the particles strongly influences the mechanism of heat transfer. For fine particles of 0.8 mm in diameter, the liquid convective heat transfer model represents adequately the experimental data, indicating that particle convective mechanism is negligible. For coarse particles of 1.5–2 mm in diameter, the liquid convective heat transfer mechanism accounts for 60 % of the overall heat transfer coefficient.
PB  - Serbian Chemical Society
T2  - Journal of the Serbian Chemical Society
T1  - Heat transfer by liquid convection in particulate fluidized beds
T1  - ПРЕНОС ТОПЛОТЕ КОНВЕКТИВНИМ МЕХАНИЗМОМ У ПАРТИКУЛАТИВНО ФЛУИДИЗОВАНОМ СЛОЈУ
EP  - 924
IS  - 7-8
SP  - 911
VL  - 87
DO  - 10.2298/JSC211216020J
ER  - 

@article{
author = "Jaćimovski, Darko R. and Brzić, Danica V. and Garić-Grulović, Radmila V. and Pjanović, Rada V. and Đuriš, Mihal M. and Arsenijević, Zorana L.J. and Bošković-Vragolović, Nevenka M.",
year = "2022",
abstract = "In this work the theoretical model for heat transfer from a wall to a liquid-solid fluidized bed by liquid convective mechanism has been proposed and developed. The model is based on thickness of boundary layer and film theory. The key parameter in the model is the distance between two adjacent particles which collide with the wall. According to the proposed model, the liquid convective heat transfer in a fluidized bed is 4 to 5 times more intense than in a single-phase flow. Additionally, the wall-to-bed heat transfer coefficient has been measured experimentally in water–glass particles fluidized bed, for different particle sizes. Comparison of the model prediction with experimental data has shown that size of the particles strongly influences the mechanism of heat transfer. For fine particles of 0.8 mm in diameter, the liquid convective heat transfer model represents adequately the experimental data, indicating that particle convective mechanism is negligible. For coarse particles of 1.5–2 mm in diameter, the liquid convective heat transfer mechanism accounts for 60 % of the overall heat transfer coefficient.",
publisher = "Serbian Chemical Society",
journal = "Journal of the Serbian Chemical Society",
title = "Heat transfer by liquid convection in particulate fluidized beds, ПРЕНОС ТОПЛОТЕ КОНВЕКТИВНИМ МЕХАНИЗМОМ У ПАРТИКУЛАТИВНО ФЛУИДИЗОВАНОМ СЛОЈУ",
pages = "924-911",
number = "7-8",
volume = "87",
doi = "10.2298/JSC211216020J"
}

Jaćimovski, D. R., Brzić, D. V., Garić-Grulović, R. V., Pjanović, R. V., Đuriš, M. M., Arsenijević, Z. L.J.,& Bošković-Vragolović, N. M.. (2022). Heat transfer by liquid convection in particulate fluidized beds. in Journal of the Serbian Chemical Society
Serbian Chemical Society., 87(7-8), 911-924.
https://doi.org/10.2298/JSC211216020J

Jaćimovski DR, Brzić DV, Garić-Grulović RV, Pjanović RV, Đuriš MM, Arsenijević ZL, Bošković-Vragolović NM. Heat transfer by liquid convection in particulate fluidized beds. in Journal of the Serbian Chemical Society. 2022;87(7-8):911-924.
doi:10.2298/JSC211216020J .

Jaćimovski, Darko R., Brzić, Danica V., Garić-Grulović, Radmila V., Pjanović, Rada V., Đuriš, Mihal M., Arsenijević, Zorana L.J., Bošković-Vragolović, Nevenka M., "Heat transfer by liquid convection in particulate fluidized beds" in Journal of the Serbian Chemical Society, 87, no. 7-8 (2022):911-924,
https://doi.org/10.2298/JSC211216020J . .