TY  - JOUR
AU  - Hrenović, Jasna
AU  - Dekić, Svjetlana
AU  - Dikić, Jelena
AU  - Kazazić, Snjezana
AU  - Durn, Goran
AU  - Rajić, Nevenka
PY  - 2020
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4521
AB  - Due to the development of resistance to antimicrobial agents, bacterium Acinetobacter baumannii is nowadays a leading cause of nosocomial outbreaks. Clinically relevant A. baumannii outside hospital settings including natural soils affected by human waste represents a public-health risk for humans and animals. The aim of this study was to investigate the potential of metal-loaded zeolites to eliminate viable A. baumannii from artificially contaminated natural soils. A. baumannii isolate was subjected to the activity of natural zeolitised tuff (NZ) and Cu-modified (CuNZ) or Ag-modified zeolite (AgNZ) in wet, slightly acidic terra rossa and slightly alkaline red palaeosol. A. baumannii survived in terra rossa and red palaeosol supplemented with 1 wt% of NZ for seven days and four months, respectively. The addition of 1 wt% of CuNZ to terra rossa and red palaeosol shortened the survival of A. baumannii to three and 14 days, respectively. The addition of 0.1 wt% of AgNZ to both soils resulted in complete removal of viable A. baumannii within 1 h of contact, while the total native heterotrophic bacterial counts remained high. Since AgNZ is prepared with a simple modification of cost-effective and environmentally friendly natural zeolite, it is a promising material for the remediation of soils contaminated with pandrug-resistant A. baumannii.
PB  - Inst Medical Research & Occupational Health, Zagreb
T2  - Arhiv za higijenu rada i toksikologiju-Archives of Industrial Hygiene and Toxicology
T1  - Metal-loaded zeolite remediation of soils contaminated with pandrug-resistant Acinetobacter baumannii
EP  - 151
IS  - 2
SP  - 146
VL  - 71
DO  - 10.2478/aiht-2020-71-3327
ER  - 

@article{
author = "Hrenović, Jasna and Dekić, Svjetlana and Dikić, Jelena and Kazazić, Snjezana and Durn, Goran and Rajić, Nevenka",
year = "2020",
abstract = "Due to the development of resistance to antimicrobial agents, bacterium Acinetobacter baumannii is nowadays a leading cause of nosocomial outbreaks. Clinically relevant A. baumannii outside hospital settings including natural soils affected by human waste represents a public-health risk for humans and animals. The aim of this study was to investigate the potential of metal-loaded zeolites to eliminate viable A. baumannii from artificially contaminated natural soils. A. baumannii isolate was subjected to the activity of natural zeolitised tuff (NZ) and Cu-modified (CuNZ) or Ag-modified zeolite (AgNZ) in wet, slightly acidic terra rossa and slightly alkaline red palaeosol. A. baumannii survived in terra rossa and red palaeosol supplemented with 1 wt% of NZ for seven days and four months, respectively. The addition of 1 wt% of CuNZ to terra rossa and red palaeosol shortened the survival of A. baumannii to three and 14 days, respectively. The addition of 0.1 wt% of AgNZ to both soils resulted in complete removal of viable A. baumannii within 1 h of contact, while the total native heterotrophic bacterial counts remained high. Since AgNZ is prepared with a simple modification of cost-effective and environmentally friendly natural zeolite, it is a promising material for the remediation of soils contaminated with pandrug-resistant A. baumannii.",
publisher = "Inst Medical Research & Occupational Health, Zagreb",
journal = "Arhiv za higijenu rada i toksikologiju-Archives of Industrial Hygiene and Toxicology",
title = "Metal-loaded zeolite remediation of soils contaminated with pandrug-resistant Acinetobacter baumannii",
pages = "151-146",
number = "2",
volume = "71",
doi = "10.2478/aiht-2020-71-3327"
}

Hrenović, J., Dekić, S., Dikić, J., Kazazić, S., Durn, G.,& Rajić, N.. (2020). Metal-loaded zeolite remediation of soils contaminated with pandrug-resistant Acinetobacter baumannii. in Arhiv za higijenu rada i toksikologiju-Archives of Industrial Hygiene and Toxicology
Inst Medical Research & Occupational Health, Zagreb., 71(2), 146-151.
https://doi.org/10.2478/aiht-2020-71-3327

Hrenović J, Dekić S, Dikić J, Kazazić S, Durn G, Rajić N. Metal-loaded zeolite remediation of soils contaminated with pandrug-resistant Acinetobacter baumannii. in Arhiv za higijenu rada i toksikologiju-Archives of Industrial Hygiene and Toxicology. 2020;71(2):146-151.
doi:10.2478/aiht-2020-71-3327 .

Hrenović, Jasna, Dekić, Svjetlana, Dikić, Jelena, Kazazić, Snjezana, Durn, Goran, Rajić, Nevenka, "Metal-loaded zeolite remediation of soils contaminated with pandrug-resistant Acinetobacter baumannii" in Arhiv za higijenu rada i toksikologiju-Archives of Industrial Hygiene and Toxicology, 71, no. 2 (2020):146-151,
https://doi.org/10.2478/aiht-2020-71-3327 . .

TY  - JOUR
AU  - Dikić, Jelena
AU  - Hrenović, Jasna
AU  - Durn, Goran
AU  - Kovacić, Ana
AU  - Rajić, Nevenka
PY  - 2019
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4109
AB  - Antibacterial activity of a natural zeolite, clinoptilolite (Z), enriched with about 0.4-0.5 mmol of Ag (Ag-Z), Cu (Cu-Z) or Zn (Zn-Z) was tested toward two strains of Gram-negative bacteria - Escherichia coli and Acinetobacter baumannii - in natural seawater from Adriatic Sea (Croatia). The Ag-Z and Cu-Z exhibited bactericidal activity toward E. coli and A. baumannii after 3 and 6 h of exposure, respectively. The Zn-Z showed antibacterial activity toward both strains, but lacking the bactericidal effect even after 24 h of exposure. All studied samples released metal cations in seawater. Concentration of Ag and Zn leached from Ag-Z and Zn-Z was higher than maximum allowable concentrations (MAC) for drinking water, whereas concentration of Cu was below MAC. Due to high concentration of Na+ in seawater (about 1.2 g Na+ dm(-3)) an ion-exchange process can be responsible for the leaching of the studied cations. The lowest extent of leaching from Cu-Z was ascribed to different position and geometry of sites occupied by Cu(II) in the clinoptilolite lattice. The antibacterial activity of M-Z was attributed to the metal cations leached from the zeolite lattice into seawater. The obtained results indicate that Cu-Z can be considered as a promising disinfectant for treatment of seawater.
PB  - Desalination Publ, Hopkinton
T2  - Desalination and Water Treatment
T1  - Antibacterial activity of metal-containing clinoptilolite in natural seawater
EP  - 79
SP  - 75
VL  - 170
DO  - 10.5004/dwt.2019.24712
ER  - 

@article{
author = "Dikić, Jelena and Hrenović, Jasna and Durn, Goran and Kovacić, Ana and Rajić, Nevenka",
year = "2019",
abstract = "Antibacterial activity of a natural zeolite, clinoptilolite (Z), enriched with about 0.4-0.5 mmol of Ag (Ag-Z), Cu (Cu-Z) or Zn (Zn-Z) was tested toward two strains of Gram-negative bacteria - Escherichia coli and Acinetobacter baumannii - in natural seawater from Adriatic Sea (Croatia). The Ag-Z and Cu-Z exhibited bactericidal activity toward E. coli and A. baumannii after 3 and 6 h of exposure, respectively. The Zn-Z showed antibacterial activity toward both strains, but lacking the bactericidal effect even after 24 h of exposure. All studied samples released metal cations in seawater. Concentration of Ag and Zn leached from Ag-Z and Zn-Z was higher than maximum allowable concentrations (MAC) for drinking water, whereas concentration of Cu was below MAC. Due to high concentration of Na+ in seawater (about 1.2 g Na+ dm(-3)) an ion-exchange process can be responsible for the leaching of the studied cations. The lowest extent of leaching from Cu-Z was ascribed to different position and geometry of sites occupied by Cu(II) in the clinoptilolite lattice. The antibacterial activity of M-Z was attributed to the metal cations leached from the zeolite lattice into seawater. The obtained results indicate that Cu-Z can be considered as a promising disinfectant for treatment of seawater.",
publisher = "Desalination Publ, Hopkinton",
journal = "Desalination and Water Treatment",
title = "Antibacterial activity of metal-containing clinoptilolite in natural seawater",
pages = "79-75",
volume = "170",
doi = "10.5004/dwt.2019.24712"
}

Dikić, J., Hrenović, J., Durn, G., Kovacić, A.,& Rajić, N.. (2019). Antibacterial activity of metal-containing clinoptilolite in natural seawater. in Desalination and Water Treatment
Desalination Publ, Hopkinton., 170, 75-79.
https://doi.org/10.5004/dwt.2019.24712

Dikić J, Hrenović J, Durn G, Kovacić A, Rajić N. Antibacterial activity of metal-containing clinoptilolite in natural seawater. in Desalination and Water Treatment. 2019;170:75-79.
doi:10.5004/dwt.2019.24712 .

Dikić, Jelena, Hrenović, Jasna, Durn, Goran, Kovacić, Ana, Rajić, Nevenka, "Antibacterial activity of metal-containing clinoptilolite in natural seawater" in Desalination and Water Treatment, 170 (2019):75-79,
https://doi.org/10.5004/dwt.2019.24712 . .

TY  - JOUR
AU  - Ivanković, Tomislav
AU  - Dikić, Jelena
AU  - du Roscoat, Sabine Rolland
AU  - Dekić, Svjetlana
AU  - Hrenović, Jasna
AU  - Ganjto, Marin
PY  - 2019
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4091
AB  - Hospital wastewaters can become a route for dissemination of antibiotic-resistant bacteria to the environment if not properly treated. Some of these bacteria are able to survive conventional disinfection treatments (e.g. chlorination, UV irradiation), which evokes the need for novel disinfection methods. The metal-exchanged zeolites were tested as novel antibacterial agents for wastewater treatment. The natural zeolite clinoptilolite enriched with silver (AgNZ) showed far better antibacterial activity towards hospital pathogenic bacterium Acinetobacter baumannii when compared with copper-exchanged zeolite (CuNZ), with minimal bactericidal concentration of 0.25-2 (AgNZ) compared with 32-64 mg L-1 (CuNZ) in a batch system and respective log 5.6 reduction compared with log 0.5 reduction in a flow system with pure bacterial culture. In the flow system with real effluent wastewater from the treatment plant, the removal of carbapenem-resistant bacteria using AgNZ was 90-100% during the 4 days of the experimental run. These results indicate that the AgNZ efficiently removes pathogenic bacteria from the wastewater, including A. baumannii, and is promising as a disinfectant material in a bead filter system.
PB  - Iwa Publishing, London
T2  - Water Science and Technology
T1  - Removal of emerging pathogenic bacteria using metal-exchanged natural zeolite bead filter
EP  - 1098
IS  - 6
SP  - 1085
VL  - 80
DO  - 10.2166/wst.2019.348
ER  - 

@article{
author = "Ivanković, Tomislav and Dikić, Jelena and du Roscoat, Sabine Rolland and Dekić, Svjetlana and Hrenović, Jasna and Ganjto, Marin",
year = "2019",
abstract = "Hospital wastewaters can become a route for dissemination of antibiotic-resistant bacteria to the environment if not properly treated. Some of these bacteria are able to survive conventional disinfection treatments (e.g. chlorination, UV irradiation), which evokes the need for novel disinfection methods. The metal-exchanged zeolites were tested as novel antibacterial agents for wastewater treatment. The natural zeolite clinoptilolite enriched with silver (AgNZ) showed far better antibacterial activity towards hospital pathogenic bacterium Acinetobacter baumannii when compared with copper-exchanged zeolite (CuNZ), with minimal bactericidal concentration of 0.25-2 (AgNZ) compared with 32-64 mg L-1 (CuNZ) in a batch system and respective log 5.6 reduction compared with log 0.5 reduction in a flow system with pure bacterial culture. In the flow system with real effluent wastewater from the treatment plant, the removal of carbapenem-resistant bacteria using AgNZ was 90-100% during the 4 days of the experimental run. These results indicate that the AgNZ efficiently removes pathogenic bacteria from the wastewater, including A. baumannii, and is promising as a disinfectant material in a bead filter system.",
publisher = "Iwa Publishing, London",
journal = "Water Science and Technology",
title = "Removal of emerging pathogenic bacteria using metal-exchanged natural zeolite bead filter",
pages = "1098-1085",
number = "6",
volume = "80",
doi = "10.2166/wst.2019.348"
}

Ivanković, T., Dikić, J., du Roscoat, S. R., Dekić, S., Hrenović, J.,& Ganjto, M.. (2019). Removal of emerging pathogenic bacteria using metal-exchanged natural zeolite bead filter. in Water Science and Technology
Iwa Publishing, London., 80(6), 1085-1098.
https://doi.org/10.2166/wst.2019.348

Ivanković T, Dikić J, du Roscoat SR, Dekić S, Hrenović J, Ganjto M. Removal of emerging pathogenic bacteria using metal-exchanged natural zeolite bead filter. in Water Science and Technology. 2019;80(6):1085-1098.
doi:10.2166/wst.2019.348 .

Ivanković, Tomislav, Dikić, Jelena, du Roscoat, Sabine Rolland, Dekić, Svjetlana, Hrenović, Jasna, Ganjto, Marin, "Removal of emerging pathogenic bacteria using metal-exchanged natural zeolite bead filter" in Water Science and Technology, 80, no. 6 (2019):1085-1098,
https://doi.org/10.2166/wst.2019.348 . .

TY  - JOUR
AU  - Dikić, Jelena
AU  - Hrenović, Jasna
AU  - Matijasević, Danka
AU  - Nikšić, Miomir
AU  - Rajić, Nevenka
PY  - 2017
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3578
AB  - Two types of zeolites-natural clinoptilolite (NZ) and synthetic zeolite A (A)-were enriched with approx. 0.25 mmol of Cu(II), Zn(II), or Ag(I) ions, and the obtained materials (M-Z) were tested against three different isolates of Escherichia coli. Two isolates were environmental isolates from waters in Serbia whereas the third one was DSM 498. Antibacterial activity was studied in different water media-nutrient-rich media (peptone water), water from Sava Lake, and commercially available spring water. The Ag-containing zeolites showed bactericidal activity in the nutrient-rich peptone water after 1 h of contact. Cu- and Zn-containing zeolites showed bactericidal activity in real water samples. Antibacterial activity of the M-Z decreases in all three examined water media in the following order: Ag-NZ ae Ag-A  gt  Cu-NZ ae Cu-A  gt  Zn-NZ  gt  gt  gt  Zn-A, suggesting that mainly the metal type and not the zeolite type have a role in the antibacterial activity. Leaching experiments showed small amounts of the leached Cu(II) and Zn(II) ions, indicating that the antibacterial activity is not due to the metal ions but should be attributed to the M-Z itself. However, leached amounts of Ag(I) from Ag-NZ and Ag-A in peptone water indicate that the released Ag(I) could be mainly responsible for the bactericidal effect of the Ag(I)-containing zeolites. Since no loss of cellular material was found, the antibacterial activity is not attributed to cytoplasmic membrane damage.
PB  - Springer Heidelberg, Heidelberg
T2  - Environmental Science and Pollution Research
T1  - Bactericidal activity of Cu-, Zn-, and Ag-containing zeolites toward Escherichia coli isolates
EP  - 20281
IS  - 25
SP  - 20273
VL  - 24
DO  - 10.1007/s11356-017-9643-8
ER  - 

@article{
author = "Dikić, Jelena and Hrenović, Jasna and Matijasević, Danka and Nikšić, Miomir and Rajić, Nevenka",
year = "2017",
abstract = "Two types of zeolites-natural clinoptilolite (NZ) and synthetic zeolite A (A)-were enriched with approx. 0.25 mmol of Cu(II), Zn(II), or Ag(I) ions, and the obtained materials (M-Z) were tested against three different isolates of Escherichia coli. Two isolates were environmental isolates from waters in Serbia whereas the third one was DSM 498. Antibacterial activity was studied in different water media-nutrient-rich media (peptone water), water from Sava Lake, and commercially available spring water. The Ag-containing zeolites showed bactericidal activity in the nutrient-rich peptone water after 1 h of contact. Cu- and Zn-containing zeolites showed bactericidal activity in real water samples. Antibacterial activity of the M-Z decreases in all three examined water media in the following order: Ag-NZ ae Ag-A  gt  Cu-NZ ae Cu-A  gt  Zn-NZ  gt  gt  gt  Zn-A, suggesting that mainly the metal type and not the zeolite type have a role in the antibacterial activity. Leaching experiments showed small amounts of the leached Cu(II) and Zn(II) ions, indicating that the antibacterial activity is not due to the metal ions but should be attributed to the M-Z itself. However, leached amounts of Ag(I) from Ag-NZ and Ag-A in peptone water indicate that the released Ag(I) could be mainly responsible for the bactericidal effect of the Ag(I)-containing zeolites. Since no loss of cellular material was found, the antibacterial activity is not attributed to cytoplasmic membrane damage.",
publisher = "Springer Heidelberg, Heidelberg",
journal = "Environmental Science and Pollution Research",
title = "Bactericidal activity of Cu-, Zn-, and Ag-containing zeolites toward Escherichia coli isolates",
pages = "20281-20273",
number = "25",
volume = "24",
doi = "10.1007/s11356-017-9643-8"
}

Dikić, J., Hrenović, J., Matijasević, D., Nikšić, M.,& Rajić, N.. (2017). Bactericidal activity of Cu-, Zn-, and Ag-containing zeolites toward Escherichia coli isolates. in Environmental Science and Pollution Research
Springer Heidelberg, Heidelberg., 24(25), 20273-20281.
https://doi.org/10.1007/s11356-017-9643-8

Dikić J, Hrenović J, Matijasević D, Nikšić M, Rajić N. Bactericidal activity of Cu-, Zn-, and Ag-containing zeolites toward Escherichia coli isolates. in Environmental Science and Pollution Research. 2017;24(25):20273-20281.
doi:10.1007/s11356-017-9643-8 .

Dikić, Jelena, Hrenović, Jasna, Matijasević, Danka, Nikšić, Miomir, Rajić, Nevenka, "Bactericidal activity of Cu-, Zn-, and Ag-containing zeolites toward Escherichia coli isolates" in Environmental Science and Pollution Research, 24, no. 25 (2017):20273-20281,
https://doi.org/10.1007/s11356-017-9643-8 . .