European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement no. 860462 and the grant agreement no. 952033

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European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement no. 860462 and the grant agreement no. 952033

Authors

Publications

Biomechanical Aspects in Bone Tumor Engineering

Menshikh, Ksenia; Banićević, Ivana; Obradović, Bojana; Rimondini, Lia

(Mary Ann Liebert Inc., 2023) 

TY  - JOUR
AU  - Menshikh, Ksenia
AU  - Banićević, Ivana
AU  - Obradović, Bojana
AU  - Rimondini, Lia
PY  - 2023
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/7027
AB  - In the past decades, anticancer drug development brought the field of tumor engineering to a new level by the need of robust test systems. Simulating tumor microenvironment in vitro remains a challenge, and osteosarcoma—the most common primary bone cancer—is no exception. The growing evidence points to the inevitable connection between biomechanical stimuli and tumor chemosensitivity and aggressiveness, thus making this component of the microenvironment a mandatory requirement to the developed models. In this review, we addressed the question: is the “in vivo - in vitro” gap in osteosarcoma engineering bridged from the perspective of biomechanical stimuli? The most notable biomechanical cues in the tumor cell microenvironment are observed and compared in the contexts of in vivo conditions and engineered three-dimensional in vitro models.
PB  - Mary Ann Liebert Inc.
T2  - Tissue Engineering - Part B: Reviews
T1  - Biomechanical Aspects in Bone Tumor Engineering
DO  - 10.1089/ten.teb.2023.0106
ER  - 
@article{
author = "Menshikh, Ksenia and Banićević, Ivana and Obradović, Bojana and Rimondini, Lia",
year = "2023",
abstract = "In the past decades, anticancer drug development brought the field of tumor engineering to a new level by the need of robust test systems. Simulating tumor microenvironment in vitro remains a challenge, and osteosarcoma—the most common primary bone cancer—is no exception. The growing evidence points to the inevitable connection between biomechanical stimuli and tumor chemosensitivity and aggressiveness, thus making this component of the microenvironment a mandatory requirement to the developed models. In this review, we addressed the question: is the “in vivo - in vitro” gap in osteosarcoma engineering bridged from the perspective of biomechanical stimuli? The most notable biomechanical cues in the tumor cell microenvironment are observed and compared in the contexts of in vivo conditions and engineered three-dimensional in vitro models.",
publisher = "Mary Ann Liebert Inc.",
journal = "Tissue Engineering - Part B: Reviews",
title = "Biomechanical Aspects in Bone Tumor Engineering",
doi = "10.1089/ten.teb.2023.0106"
}
Menshikh, K., Banićević, I., Obradović, B.,& Rimondini, L.. (2023). Biomechanical Aspects in Bone Tumor Engineering. in Tissue Engineering - Part B: Reviews
Mary Ann Liebert Inc...
https://doi.org/10.1089/ten.teb.2023.0106
Menshikh K, Banićević I, Obradović B, Rimondini L. Biomechanical Aspects in Bone Tumor Engineering. in Tissue Engineering - Part B: Reviews. 2023;.
doi:10.1089/ten.teb.2023.0106 .
Menshikh, Ksenia, Banićević, Ivana, Obradović, Bojana, Rimondini, Lia, "Biomechanical Aspects in Bone Tumor Engineering" in Tissue Engineering - Part B: Reviews (2023),
https://doi.org/10.1089/ten.teb.2023.0106 . .