TY  - JOUR
AU  - Milovanović, Stoja
AU  - Hollermann, Gesa
AU  - Errenst, Cornelia
AU  - Pajnik, Jelena
AU  - Frerich, Sulamith
AU  - Kroll, Stephen
AU  - Rezwan, Kurosch
AU  - Ivanović, Jasna
PY  - 2018
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4037
AB  - Biodegradable polymers with antibacterial properties are highly desirable materials for active food packaging applications. Thymol, a dietary monoterpene phenol with a strong antibacterial activity is abundant in plants belonging to the genus Thymus. This study presents two approaches for supercritical CO2 impregnation of poly (lactic acid)(PLA)/poly(epsilon-caprolactone)(PCL) blended films to induce antibacterial properties of the material: (i) a batch impregnation process for loading pure thymol, and (ii) an integrated supercritical extraction-impregnation process for isolation of thyme extract and its incorporation into the films, operated in both batch or semi-continuous modes with supercritical solution circulation. The PCL content in films, impregnation time and CO2 flow regime were varied to maximize loading of the films with thymol or thyme extract with preserving films' structure and thermal stability. Representative film samples impregnated with thymol and thyme extract were tested against Gram ( - ) (Escherichia col) and Gram( + ) (Bacillus subtilis) model strains, by measuring their metabolic activity and re-cultivation after exposure to the films. The film containing thymol (35.8 wt%) showed a strong antibacterial activity leading to a total reduction of bacterial cell viability. Proposed processes enable fast, controlled and organic solvent-free fabrication of the PLA/PCL films containing natural antibacterial substances at moderately low temperature, with a compact structure and a good thermal stability, for potential use as active food packaging materials.
PB  - Elsevier Science Bv, Amsterdam
T2  - Food Research International
T1  - Supercritical CO2 impregnation of PLA/PCL films with natural substances for bacterial growth control in food packaging
EP  - 495
SP  - 486
VL  - 107
DO  - 10.1016/j.foodres.2018.02.065
ER  - 

@article{
author = "Milovanović, Stoja and Hollermann, Gesa and Errenst, Cornelia and Pajnik, Jelena and Frerich, Sulamith and Kroll, Stephen and Rezwan, Kurosch and Ivanović, Jasna",
year = "2018",
abstract = "Biodegradable polymers with antibacterial properties are highly desirable materials for active food packaging applications. Thymol, a dietary monoterpene phenol with a strong antibacterial activity is abundant in plants belonging to the genus Thymus. This study presents two approaches for supercritical CO2 impregnation of poly (lactic acid)(PLA)/poly(epsilon-caprolactone)(PCL) blended films to induce antibacterial properties of the material: (i) a batch impregnation process for loading pure thymol, and (ii) an integrated supercritical extraction-impregnation process for isolation of thyme extract and its incorporation into the films, operated in both batch or semi-continuous modes with supercritical solution circulation. The PCL content in films, impregnation time and CO2 flow regime were varied to maximize loading of the films with thymol or thyme extract with preserving films' structure and thermal stability. Representative film samples impregnated with thymol and thyme extract were tested against Gram ( - ) (Escherichia col) and Gram( + ) (Bacillus subtilis) model strains, by measuring their metabolic activity and re-cultivation after exposure to the films. The film containing thymol (35.8 wt%) showed a strong antibacterial activity leading to a total reduction of bacterial cell viability. Proposed processes enable fast, controlled and organic solvent-free fabrication of the PLA/PCL films containing natural antibacterial substances at moderately low temperature, with a compact structure and a good thermal stability, for potential use as active food packaging materials.",
publisher = "Elsevier Science Bv, Amsterdam",
journal = "Food Research International",
title = "Supercritical CO2 impregnation of PLA/PCL films with natural substances for bacterial growth control in food packaging",
pages = "495-486",
volume = "107",
doi = "10.1016/j.foodres.2018.02.065"
}

Milovanović, S., Hollermann, G., Errenst, C., Pajnik, J., Frerich, S., Kroll, S., Rezwan, K.,& Ivanović, J.. (2018). Supercritical CO2 impregnation of PLA/PCL films with natural substances for bacterial growth control in food packaging. in Food Research International
Elsevier Science Bv, Amsterdam., 107, 486-495.
https://doi.org/10.1016/j.foodres.2018.02.065

Milovanović S, Hollermann G, Errenst C, Pajnik J, Frerich S, Kroll S, Rezwan K, Ivanović J. Supercritical CO2 impregnation of PLA/PCL films with natural substances for bacterial growth control in food packaging. in Food Research International. 2018;107:486-495.
doi:10.1016/j.foodres.2018.02.065 .

Milovanović, Stoja, Hollermann, Gesa, Errenst, Cornelia, Pajnik, Jelena, Frerich, Sulamith, Kroll, Stephen, Rezwan, Kurosch, Ivanović, Jasna, "Supercritical CO2 impregnation of PLA/PCL films with natural substances for bacterial growth control in food packaging" in Food Research International, 107 (2018):486-495,
https://doi.org/10.1016/j.foodres.2018.02.065 . .