TY  - JOUR
AU  - Ivanović, Jasna
AU  - Žižović, Irena
AU  - Ristić, Mihailo S.
AU  - Stamenić, Marko
AU  - Skala, Dejan
PY  - 2011
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/1920
AB  - The goal of present work was to investigate and explain kinetics and mass transfer phenomena occurring during the SFE from the mixture of two plants with different initial composition. The extractions from pure clove, oregano and thyme as well as from clove/oregano (C/O) and clove/thyme (C/T) mixtures with various initial compositions of plant material were carried out using supercritical CO2 at 10 MPa and 40 degrees C. The results indicated that presence of light compounds in supercritical CO2 originated from the oregano leaves or thyme at the beginning of extraction process increases the extraction rate of compounds from clove bud. Only small added amounts of oregano or thyme to clove bud (C/O - 90:10%, w/w; or C/T - 84:16%, w/w) in the starting plant mixture had the same effect resulted in the similar and the highest increase of the extraction rate and had negligible influence on total extraction yield compared to extract isolated from pure clove. Different mathematical models were used for simulation of experimental data which showed that the highest increase of the solubility of extractable compounds in supercritical CO2 as well as the highest mass transfer rate in the solid phase during extractions existed during extraction from C/O (90:10, w/w) and C/T (84:16, w/w) mixtures. Decrease of SC CO2 consumption or shorter time of extraction necessary for achieving desired extract yield in the case of SFE of the clove buds could be important for industrial-scale application.
PB  - Elsevier, Amsterdam
T2  - Journal of Supercritical Fluids
T1  - The analysis of simultaneous clove/oregano and clove/thyme supercritical extraction
EP  - 991
IS  - 3
SP  - 983
VL  - 55
DO  - 10.1016/j.supflu.2010.09.012
ER  - 

@article{
author = "Ivanović, Jasna and Žižović, Irena and Ristić, Mihailo S. and Stamenić, Marko and Skala, Dejan",
year = "2011",
abstract = "The goal of present work was to investigate and explain kinetics and mass transfer phenomena occurring during the SFE from the mixture of two plants with different initial composition. The extractions from pure clove, oregano and thyme as well as from clove/oregano (C/O) and clove/thyme (C/T) mixtures with various initial compositions of plant material were carried out using supercritical CO2 at 10 MPa and 40 degrees C. The results indicated that presence of light compounds in supercritical CO2 originated from the oregano leaves or thyme at the beginning of extraction process increases the extraction rate of compounds from clove bud. Only small added amounts of oregano or thyme to clove bud (C/O - 90:10%, w/w; or C/T - 84:16%, w/w) in the starting plant mixture had the same effect resulted in the similar and the highest increase of the extraction rate and had negligible influence on total extraction yield compared to extract isolated from pure clove. Different mathematical models were used for simulation of experimental data which showed that the highest increase of the solubility of extractable compounds in supercritical CO2 as well as the highest mass transfer rate in the solid phase during extractions existed during extraction from C/O (90:10, w/w) and C/T (84:16, w/w) mixtures. Decrease of SC CO2 consumption or shorter time of extraction necessary for achieving desired extract yield in the case of SFE of the clove buds could be important for industrial-scale application.",
publisher = "Elsevier, Amsterdam",
journal = "Journal of Supercritical Fluids",
title = "The analysis of simultaneous clove/oregano and clove/thyme supercritical extraction",
pages = "991-983",
number = "3",
volume = "55",
doi = "10.1016/j.supflu.2010.09.012"
}

Ivanović, J., Žižović, I., Ristić, M. S., Stamenić, M.,& Skala, D.. (2011). The analysis of simultaneous clove/oregano and clove/thyme supercritical extraction. in Journal of Supercritical Fluids
Elsevier, Amsterdam., 55(3), 983-991.
https://doi.org/10.1016/j.supflu.2010.09.012

Ivanović J, Žižović I, Ristić MS, Stamenić M, Skala D. The analysis of simultaneous clove/oregano and clove/thyme supercritical extraction. in Journal of Supercritical Fluids. 2011;55(3):983-991.
doi:10.1016/j.supflu.2010.09.012 .

Ivanović, Jasna, Žižović, Irena, Ristić, Mihailo S., Stamenić, Marko, Skala, Dejan, "The analysis of simultaneous clove/oregano and clove/thyme supercritical extraction" in Journal of Supercritical Fluids, 55, no. 3 (2011):983-991,
https://doi.org/10.1016/j.supflu.2010.09.012 . .

TY  - JOUR
AU  - Glišić, Sandra
AU  - Ristić, Mihailo S.
AU  - Skala, Dejan
PY  - 2011
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/1933
AB  - A wide spectrum of phytochemicals could be isolated from sage (Salvia officinalis L) using different extraction or distillation technique: the supercritical fluid extraction (SFE), the volatiles compounds (monoterpenes and sesquiterpenes) isolation using hydrodistillation or higher molecular compounds with Soxhlet extraction or ultrasound-assisted extraction. The combination of ultrasound-assisted extraction followed by re-extraction of obtained extract with supercritical CO2 was performed in this study. The goal of performed investigation was to concentrate diterpenes present in sage extract which are generally considered to be responsible for antioxidant activity of extracted compounds. The fractionation using the supercritical CO2, and different combination of the ultrasound-assisted solvent extractions (water-ethanol mixture or only water) followed by supercritical CO2 re-extraction of obtained extract or treated plant material were analyzed and compared. Based on the results of these investigations it could be proposed the best extraction procedure: the ultrasound pretreatment of plant material with distilled water and re-extraction of plant material (residue) using supercritical CO2. That procedure gives two valuable products: the ultrasound extract which is rich in sugars and possess the immunomodulatory activity and supercritical extract which is rich in diterpenes and sesquiterpenes.
PB  - Elsevier Science Bv, Amsterdam
T2  - Ultrasonics Sonochemistry
T1  - The combined extraction of sage (Salvia officinalis L.): Ultrasound followed by supercritical CO2 extraction
EP  - 326
IS  - 1
SP  - 318
VL  - 18
DO  - 10.1016/j.ultsonch.2010.06.011
ER  - 

@article{
author = "Glišić, Sandra and Ristić, Mihailo S. and Skala, Dejan",
year = "2011",
abstract = "A wide spectrum of phytochemicals could be isolated from sage (Salvia officinalis L) using different extraction or distillation technique: the supercritical fluid extraction (SFE), the volatiles compounds (monoterpenes and sesquiterpenes) isolation using hydrodistillation or higher molecular compounds with Soxhlet extraction or ultrasound-assisted extraction. The combination of ultrasound-assisted extraction followed by re-extraction of obtained extract with supercritical CO2 was performed in this study. The goal of performed investigation was to concentrate diterpenes present in sage extract which are generally considered to be responsible for antioxidant activity of extracted compounds. The fractionation using the supercritical CO2, and different combination of the ultrasound-assisted solvent extractions (water-ethanol mixture or only water) followed by supercritical CO2 re-extraction of obtained extract or treated plant material were analyzed and compared. Based on the results of these investigations it could be proposed the best extraction procedure: the ultrasound pretreatment of plant material with distilled water and re-extraction of plant material (residue) using supercritical CO2. That procedure gives two valuable products: the ultrasound extract which is rich in sugars and possess the immunomodulatory activity and supercritical extract which is rich in diterpenes and sesquiterpenes.",
publisher = "Elsevier Science Bv, Amsterdam",
journal = "Ultrasonics Sonochemistry",
title = "The combined extraction of sage (Salvia officinalis L.): Ultrasound followed by supercritical CO2 extraction",
pages = "326-318",
number = "1",
volume = "18",
doi = "10.1016/j.ultsonch.2010.06.011"
}

Glišić, S., Ristić, M. S.,& Skala, D.. (2011). The combined extraction of sage (Salvia officinalis L.): Ultrasound followed by supercritical CO2 extraction. in Ultrasonics Sonochemistry
Elsevier Science Bv, Amsterdam., 18(1), 318-326.
https://doi.org/10.1016/j.ultsonch.2010.06.011

Glišić S, Ristić MS, Skala D. The combined extraction of sage (Salvia officinalis L.): Ultrasound followed by supercritical CO2 extraction. in Ultrasonics Sonochemistry. 2011;18(1):318-326.
doi:10.1016/j.ultsonch.2010.06.011 .

Glišić, Sandra, Ristić, Mihailo S., Skala, Dejan, "The combined extraction of sage (Salvia officinalis L.): Ultrasound followed by supercritical CO2 extraction" in Ultrasonics Sonochemistry, 18, no. 1 (2011):318-326,
https://doi.org/10.1016/j.ultsonch.2010.06.011 . .

TY  - JOUR
AU  - Glišić, Sandra
AU  - Skala, Dejan
PY  - 2010
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/1592
AB  - The analysis of phase equilibrium between methanol and glycerides during methyl esters of fatty acids (FAME or biodiesel) synthesis at high pressure and temperature is very important for describing the kinetic and process design. It was studied at pressure between 1.1 and 28.0 MPa and temperature from 150 to 270 degrees C. The transition of phases and composition of identified phases was calculated using RK-Aspen EOS and obtained values were also compared to experimentally determined data at subcritical condition (1.1-4.5 MPa and 150-210 degrees C). Results of experimental investigation, as well as performed simulation of some specified composition of reaction mixture, showed that system of triglycerides and methanol, at the beginning of reaction (at all analysed conditions except for supercritical state of mixture) is in equilibrium between two liquid phases. During the methanolysis of triglycerides, the phase's distribution was changed accordingly and it highly depends on actual composition of reaction mixture, temperature and pressure. Calculated and measured values indicated that distribution of methanol between the oil phase, the methyl esters, and the glycerol rich phase exists and depends of working condition. As a consequence of fact, that the methanolysis of triglycerides (oil) is mainly realized in the oil-rich phase, at the end of reaction, after all triglycerides are converted into FAME and glycerol, the oil phase disappears. Furthermore, according to the results of phase composition calculation, it was shown that from the beginning to the end of reaction one phase only exists, for methanolysis performed at 270 degrees C and 20.0 MPa.
PB  - Elsevier, Amsterdam
T2  - Journal of Supercritical Fluids
T1  - Phase transition at subcritical and supercritical conditions of triglycerides methanolysis
EP  - 80
IS  - 1
SP  - 71
VL  - 54
DO  - 10.1016/j.supflu.2010.03.005
ER  - 

@article{
author = "Glišić, Sandra and Skala, Dejan",
year = "2010",
abstract = "The analysis of phase equilibrium between methanol and glycerides during methyl esters of fatty acids (FAME or biodiesel) synthesis at high pressure and temperature is very important for describing the kinetic and process design. It was studied at pressure between 1.1 and 28.0 MPa and temperature from 150 to 270 degrees C. The transition of phases and composition of identified phases was calculated using RK-Aspen EOS and obtained values were also compared to experimentally determined data at subcritical condition (1.1-4.5 MPa and 150-210 degrees C). Results of experimental investigation, as well as performed simulation of some specified composition of reaction mixture, showed that system of triglycerides and methanol, at the beginning of reaction (at all analysed conditions except for supercritical state of mixture) is in equilibrium between two liquid phases. During the methanolysis of triglycerides, the phase's distribution was changed accordingly and it highly depends on actual composition of reaction mixture, temperature and pressure. Calculated and measured values indicated that distribution of methanol between the oil phase, the methyl esters, and the glycerol rich phase exists and depends of working condition. As a consequence of fact, that the methanolysis of triglycerides (oil) is mainly realized in the oil-rich phase, at the end of reaction, after all triglycerides are converted into FAME and glycerol, the oil phase disappears. Furthermore, according to the results of phase composition calculation, it was shown that from the beginning to the end of reaction one phase only exists, for methanolysis performed at 270 degrees C and 20.0 MPa.",
publisher = "Elsevier, Amsterdam",
journal = "Journal of Supercritical Fluids",
title = "Phase transition at subcritical and supercritical conditions of triglycerides methanolysis",
pages = "80-71",
number = "1",
volume = "54",
doi = "10.1016/j.supflu.2010.03.005"
}

Glišić, S.,& Skala, D.. (2010). Phase transition at subcritical and supercritical conditions of triglycerides methanolysis. in Journal of Supercritical Fluids
Elsevier, Amsterdam., 54(1), 71-80.
https://doi.org/10.1016/j.supflu.2010.03.005

Glišić S, Skala D. Phase transition at subcritical and supercritical conditions of triglycerides methanolysis. in Journal of Supercritical Fluids. 2010;54(1):71-80.
doi:10.1016/j.supflu.2010.03.005 .

Glišić, Sandra, Skala, Dejan, "Phase transition at subcritical and supercritical conditions of triglycerides methanolysis" in Journal of Supercritical Fluids, 54, no. 1 (2010):71-80,
https://doi.org/10.1016/j.supflu.2010.03.005 . .

TY  - JOUR
AU  - Glišić, Sandra
AU  - Ivanović, Jasna
AU  - Ristić, Mihailo S.
AU  - Skala, Dejan
PY  - 2010
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/1676
AB  - The supercritical carbon dioxide (SFE) extraction of Dalmatian sage (Salvia officinalis L) was investigated and compared to extraction performed by Soxhlet ethanol-water (70:30) mixture extraction (SE) and hydrodistillation (HD). The supercritical extraction allowed isolation of wide spectrum of phytochemicals, while other applied methods were limited to either volatiles (HD) or high molecular compounds isolation (SE). The kinetics of the supercritical extraction and fractionation within the pressure range of 10-30 MPa at 50 degrees C were also analyzed as well as the chemical compositions of total extract and partial or differential fractions isolated at different CO2. consumption. Volatile fraction could be isolated at low pressure and low CO2 consumption, whereby the pressures between 10 and 15 MPa followed by increased CO2 consumption were favourable for obtaining desired selectivity of diterpenes which contain compounds with expressed antioxidative characteristics.
PB  - Elsevier Science Bv, Amsterdam
T2  - Journal of Supercritical Fluids
T1  - Extraction of sage (Salvia officinalis L.) by supercritical CO2: Kinetic data, chemical composition and selectivity of diterpenes
EP  - 70
IS  - 1
SP  - 62
VL  - 52
DO  - 10.1016/j.supflu.2009.11.009
ER  - 

@article{
author = "Glišić, Sandra and Ivanović, Jasna and Ristić, Mihailo S. and Skala, Dejan",
year = "2010",
abstract = "The supercritical carbon dioxide (SFE) extraction of Dalmatian sage (Salvia officinalis L) was investigated and compared to extraction performed by Soxhlet ethanol-water (70:30) mixture extraction (SE) and hydrodistillation (HD). The supercritical extraction allowed isolation of wide spectrum of phytochemicals, while other applied methods were limited to either volatiles (HD) or high molecular compounds isolation (SE). The kinetics of the supercritical extraction and fractionation within the pressure range of 10-30 MPa at 50 degrees C were also analyzed as well as the chemical compositions of total extract and partial or differential fractions isolated at different CO2. consumption. Volatile fraction could be isolated at low pressure and low CO2 consumption, whereby the pressures between 10 and 15 MPa followed by increased CO2 consumption were favourable for obtaining desired selectivity of diterpenes which contain compounds with expressed antioxidative characteristics.",
publisher = "Elsevier Science Bv, Amsterdam",
journal = "Journal of Supercritical Fluids",
title = "Extraction of sage (Salvia officinalis L.) by supercritical CO2: Kinetic data, chemical composition and selectivity of diterpenes",
pages = "70-62",
number = "1",
volume = "52",
doi = "10.1016/j.supflu.2009.11.009"
}

Glišić, S., Ivanović, J., Ristić, M. S.,& Skala, D.. (2010). Extraction of sage (Salvia officinalis L.) by supercritical CO2: Kinetic data, chemical composition and selectivity of diterpenes. in Journal of Supercritical Fluids
Elsevier Science Bv, Amsterdam., 52(1), 62-70.
https://doi.org/10.1016/j.supflu.2009.11.009

Glišić S, Ivanović J, Ristić MS, Skala D. Extraction of sage (Salvia officinalis L.) by supercritical CO2: Kinetic data, chemical composition and selectivity of diterpenes. in Journal of Supercritical Fluids. 2010;52(1):62-70.
doi:10.1016/j.supflu.2009.11.009 .

Glišić, Sandra, Ivanović, Jasna, Ristić, Mihailo S., Skala, Dejan, "Extraction of sage (Salvia officinalis L.) by supercritical CO2: Kinetic data, chemical composition and selectivity of diterpenes" in Journal of Supercritical Fluids, 52, no. 1 (2010):62-70,
https://doi.org/10.1016/j.supflu.2009.11.009 . .

TY  - JOUR
AU  - Stamenić, Marko
AU  - Žižović, Irena
AU  - Eggers, Rudolf
AU  - Jaeger, Philip
AU  - Heinrich, H.
AU  - Roj, E.
AU  - Ivanović, Jasna
AU  - Skala, Dejan
PY  - 2010
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/1675
AB  - Swelling of plant material belonging to several plant families and the influence of swelling on supercritical fluid extraction process were investigated in this study. While swelling of Lamiaceae family species as well as hop cones and pellets occurred during the exposure of plant material to supercritical carbon dioxide, swelling of valerian root and ginger rhizome happened after the decompression step. Optimal pretreatment of herbaceous matrix which will enable commencement of continuous extraction from already swollen plant material was defined on the basis of swelling test results. Experimental results were modeled and energy savings due to the optimal processing on the laboratory scale were calculated. Sorption of carbon dioxide into the hop pellet was measured and the diffusion coefficient in the solid phase was determined. Obtained results indicated that the effective diffusion coefficient in the hop pellet was increased by one order of magnitude due to swelling.
PB  - Elsevier, Amsterdam
T2  - Journal of Supercritical Fluids
T1  - Swelling of plant material in supercritical carbon dioxide
EP  - 133
IS  - 1
SP  - 125
VL  - 52
DO  - 10.1016/j.supflu.2009.12.004
ER  - 

@article{
author = "Stamenić, Marko and Žižović, Irena and Eggers, Rudolf and Jaeger, Philip and Heinrich, H. and Roj, E. and Ivanović, Jasna and Skala, Dejan",
year = "2010",
abstract = "Swelling of plant material belonging to several plant families and the influence of swelling on supercritical fluid extraction process were investigated in this study. While swelling of Lamiaceae family species as well as hop cones and pellets occurred during the exposure of plant material to supercritical carbon dioxide, swelling of valerian root and ginger rhizome happened after the decompression step. Optimal pretreatment of herbaceous matrix which will enable commencement of continuous extraction from already swollen plant material was defined on the basis of swelling test results. Experimental results were modeled and energy savings due to the optimal processing on the laboratory scale were calculated. Sorption of carbon dioxide into the hop pellet was measured and the diffusion coefficient in the solid phase was determined. Obtained results indicated that the effective diffusion coefficient in the hop pellet was increased by one order of magnitude due to swelling.",
publisher = "Elsevier, Amsterdam",
journal = "Journal of Supercritical Fluids",
title = "Swelling of plant material in supercritical carbon dioxide",
pages = "133-125",
number = "1",
volume = "52",
doi = "10.1016/j.supflu.2009.12.004"
}

Stamenić, M., Žižović, I., Eggers, R., Jaeger, P., Heinrich, H., Roj, E., Ivanović, J.,& Skala, D.. (2010). Swelling of plant material in supercritical carbon dioxide. in Journal of Supercritical Fluids
Elsevier, Amsterdam., 52(1), 125-133.
https://doi.org/10.1016/j.supflu.2009.12.004

Stamenić M, Žižović I, Eggers R, Jaeger P, Heinrich H, Roj E, Ivanović J, Skala D. Swelling of plant material in supercritical carbon dioxide. in Journal of Supercritical Fluids. 2010;52(1):125-133.
doi:10.1016/j.supflu.2009.12.004 .

Stamenić, Marko, Žižović, Irena, Eggers, Rudolf, Jaeger, Philip, Heinrich, H., Roj, E., Ivanović, Jasna, Skala, Dejan, "Swelling of plant material in supercritical carbon dioxide" in Journal of Supercritical Fluids, 52, no. 1 (2010):125-133,
https://doi.org/10.1016/j.supflu.2009.12.004 . .

TY  - JOUR
AU  - Milojević, Svetomir
AU  - Glišić, Sandra
AU  - Skala, Dejan
PY  - 2010
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/1663
AB  - The separation in a batch vacuum column of the essential oil of common juniper berries (Juniperus communis L., from the southern part of Serbia) was analyzed. The main goal of the analyzed separation process was to isolate several fractions from the essential oil which mainly contained á-pinene, sabinene and myrcene. These compounds contain about 65 mass% of the essential oil produced by hydrodistillation from the juniper berries originated from the southern part of Serbia. The results of experimental work in a laboratory column with 36 theoretical stages under vacuum (8.0-3.35 kPa) was simulated using Aspen software, and a proposed mathematical model was used to analyze some other operating conditions for fractionation of juniper berry's oil (number of plates: 25, 36 and 45 and reflux ratio: 2-10). According to the results of performed simulations, the most acceptable separation procedure which takes into account the prices of raw materials and distillate (á-pinene) as well as consumed energy was proposed.
AB  - U ovom radu je ispitivana separacija etarskog ulja iz bobica kleke (Juniperus communis L. sa podneblja južne Srbije) postupkom šaržne vakuum destilacije. Glavni cilj laboratorijskih ispitivanja je usmeren ka izdvajanju pojedinih frakcija iz etarskog ulja kleke koje sadrže u većem procentu á-pinen, sabinen i mircen, a čine 65 mas% etarskog ulja dobijenog hidrodestilacijom bobica kleke. Rezultati eksperimentalnih ispitivanja sprovedenih šaržnom destilacijom pod vakuumom (8,0-3,35 kPa) u koloni sa 36 teorijskih podova su bili osnova za definisanje odgovarajućeg matematičkog modela i njegovog rešavanja primenom softverskog paketa Aspen. Dobijeno je dobro slaganje između eksperimentalnih vrednosti i vrednosti izračunatih na osnovu ovog modela. Potvrđena korektnost modela iskorišćena je za analizu uticaja različitih operativnih parametara (refluksni odnos od 2 do 10) i konstrukcionih karakteristika kolone (broj podova: 25, 36 i 45) na efekte separacije etarskog ulja kleke. Rezultati su pokazali, na osnovu analize uticaja cene ulazne sirovine, cene izdvojenih frakcija (á-pinen; smeše á-pinena sabinena, mircena) i ukupno utrošene energije za separaciju, da je u laboratorijskim uslovima izvedeno frakcionisanje etarskog ulja kleke najprihvatljivije.
PB  - Association of the Chemical Engineers of Serbia
T2  - Chemical Industry & Chemical Engineering Quarterly
T1  - The batch fractionation of Juniperus communis L. essential oil: Experimental study, mathematical simulation and process economy
T1  - Frakciona destilacija etarskog ulja Juniperus communis L. - laboratorijska ispitivanja, matematička simulacija i ekonomika procesa
EP  - 191
IS  - 2
SP  - 183
VL  - 16
DO  - 10.2298/CICEQ100317026M
ER  - 

@article{
author = "Milojević, Svetomir and Glišić, Sandra and Skala, Dejan",
year = "2010",
abstract = "The separation in a batch vacuum column of the essential oil of common juniper berries (Juniperus communis L., from the southern part of Serbia) was analyzed. The main goal of the analyzed separation process was to isolate several fractions from the essential oil which mainly contained á-pinene, sabinene and myrcene. These compounds contain about 65 mass% of the essential oil produced by hydrodistillation from the juniper berries originated from the southern part of Serbia. The results of experimental work in a laboratory column with 36 theoretical stages under vacuum (8.0-3.35 kPa) was simulated using Aspen software, and a proposed mathematical model was used to analyze some other operating conditions for fractionation of juniper berry's oil (number of plates: 25, 36 and 45 and reflux ratio: 2-10). According to the results of performed simulations, the most acceptable separation procedure which takes into account the prices of raw materials and distillate (á-pinene) as well as consumed energy was proposed., U ovom radu je ispitivana separacija etarskog ulja iz bobica kleke (Juniperus communis L. sa podneblja južne Srbije) postupkom šaržne vakuum destilacije. Glavni cilj laboratorijskih ispitivanja je usmeren ka izdvajanju pojedinih frakcija iz etarskog ulja kleke koje sadrže u većem procentu á-pinen, sabinen i mircen, a čine 65 mas% etarskog ulja dobijenog hidrodestilacijom bobica kleke. Rezultati eksperimentalnih ispitivanja sprovedenih šaržnom destilacijom pod vakuumom (8,0-3,35 kPa) u koloni sa 36 teorijskih podova su bili osnova za definisanje odgovarajućeg matematičkog modela i njegovog rešavanja primenom softverskog paketa Aspen. Dobijeno je dobro slaganje između eksperimentalnih vrednosti i vrednosti izračunatih na osnovu ovog modela. Potvrđena korektnost modela iskorišćena je za analizu uticaja različitih operativnih parametara (refluksni odnos od 2 do 10) i konstrukcionih karakteristika kolone (broj podova: 25, 36 i 45) na efekte separacije etarskog ulja kleke. Rezultati su pokazali, na osnovu analize uticaja cene ulazne sirovine, cene izdvojenih frakcija (á-pinen; smeše á-pinena sabinena, mircena) i ukupno utrošene energije za separaciju, da je u laboratorijskim uslovima izvedeno frakcionisanje etarskog ulja kleke najprihvatljivije.",
publisher = "Association of the Chemical Engineers of Serbia",
journal = "Chemical Industry & Chemical Engineering Quarterly",
title = "The batch fractionation of Juniperus communis L. essential oil: Experimental study, mathematical simulation and process economy, Frakciona destilacija etarskog ulja Juniperus communis L. - laboratorijska ispitivanja, matematička simulacija i ekonomika procesa",
pages = "191-183",
number = "2",
volume = "16",
doi = "10.2298/CICEQ100317026M"
}

Milojević, S., Glišić, S.,& Skala, D.. (2010). The batch fractionation of Juniperus communis L. essential oil: Experimental study, mathematical simulation and process economy. in Chemical Industry & Chemical Engineering Quarterly
Association of the Chemical Engineers of Serbia., 16(2), 183-191.
https://doi.org/10.2298/CICEQ100317026M

Milojević S, Glišić S, Skala D. The batch fractionation of Juniperus communis L. essential oil: Experimental study, mathematical simulation and process economy. in Chemical Industry & Chemical Engineering Quarterly. 2010;16(2):183-191.
doi:10.2298/CICEQ100317026M .

Milojević, Svetomir, Glišić, Sandra, Skala, Dejan, "The batch fractionation of Juniperus communis L. essential oil: Experimental study, mathematical simulation and process economy" in Chemical Industry & Chemical Engineering Quarterly, 16, no. 2 (2010):183-191,
https://doi.org/10.2298/CICEQ100317026M . .

TY  - JOUR
AU  - Glišić, Sandra
AU  - Skala, Dejan
PY  - 2009
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/1496
AB  - The main goal of this study is analysis the existing and recently published data related to design of larger scale plant for biodiesel synthesis at supercritical conditions. Such analysis was focused on the problem of insufficiency of the previously in the literature published industrial plant design simulation. A continuous process flowsheet for biodiesel production from triglycerides under supercritical conditions of alcohol (SCA) was analyzed and influence of triglycerides degree of conversion on overall energy consumption in SCA was examined. A comparison between the homogenous alkali-catalyzed alcoholysis (HACA) and the supercritical methanolysis of triglyceride was made in order to point out the advantages and disadvantages of each of analyzed process. Furthermore, the usage of energy in each step and environmentally weak points of both process are discussed and the possible solutions for avoiding them are proposed.
PB  - Elsevier, Amsterdam
T2  - Journal of Supercritical Fluids
T1  - The problems in design and detailed analyses of energy consumption for biodiesel synthesis at supercritical conditions
EP  - 301
IS  - 2
SP  - 293
VL  - 49
DO  - 10.1016/j.supflu.2008.12.011
ER  - 

@article{
author = "Glišić, Sandra and Skala, Dejan",
year = "2009",
abstract = "The main goal of this study is analysis the existing and recently published data related to design of larger scale plant for biodiesel synthesis at supercritical conditions. Such analysis was focused on the problem of insufficiency of the previously in the literature published industrial plant design simulation. A continuous process flowsheet for biodiesel production from triglycerides under supercritical conditions of alcohol (SCA) was analyzed and influence of triglycerides degree of conversion on overall energy consumption in SCA was examined. A comparison between the homogenous alkali-catalyzed alcoholysis (HACA) and the supercritical methanolysis of triglyceride was made in order to point out the advantages and disadvantages of each of analyzed process. Furthermore, the usage of energy in each step and environmentally weak points of both process are discussed and the possible solutions for avoiding them are proposed.",
publisher = "Elsevier, Amsterdam",
journal = "Journal of Supercritical Fluids",
title = "The problems in design and detailed analyses of energy consumption for biodiesel synthesis at supercritical conditions",
pages = "301-293",
number = "2",
volume = "49",
doi = "10.1016/j.supflu.2008.12.011"
}

Glišić, S.,& Skala, D.. (2009). The problems in design and detailed analyses of energy consumption for biodiesel synthesis at supercritical conditions. in Journal of Supercritical Fluids
Elsevier, Amsterdam., 49(2), 293-301.
https://doi.org/10.1016/j.supflu.2008.12.011

Glišić S, Skala D. The problems in design and detailed analyses of energy consumption for biodiesel synthesis at supercritical conditions. in Journal of Supercritical Fluids. 2009;49(2):293-301.
doi:10.1016/j.supflu.2008.12.011 .

Glišić, Sandra, Skala, Dejan, "The problems in design and detailed analyses of energy consumption for biodiesel synthesis at supercritical conditions" in Journal of Supercritical Fluids, 49, no. 2 (2009):293-301,
https://doi.org/10.1016/j.supflu.2008.12.011 . .

TY  - JOUR
AU  - Ivanović, Jasna
AU  - Žižović, Irena
AU  - Petrović, Slobodan
AU  - Skala, Dejan
PY  - 2009
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/1392
AB  - The present study was aimed to investigate and compare the efficiency of different methods for the isolation extract from a plant material. Extracts from dried leaves of Aloe vera (A. barbadensis Mill.) and Sweet Bay (Laurus nobilis L.) were obtained applying the following techniques: supercritical carbon dioxide (SC CO2) extraction at 30 MPa and 100°C, a combined ultrasonic extraction and pre-treatment using SC CO2 (US-SCCO2), and a conventional ultrasonic extraction (US) with 96% ethanol. US-SCCO2 resulted in much higher yields of extracts of aloe and bay compared to SC CO2 extraction. Determined extract's yield was used for calculating the maximum useful work and exergy loss as a measure of irreversibility of the extraction process. Calculated maximum useful work per 1 kg of the extract was ranged from 0.7 to 226 kJ while estimated values of the exergy loss were from 48 to 416 kJ per 1 kg of the extract. The maximum useful work and exergy loss have the largest value for SCE much more than for other processes of extraction (US and US-SCCO2). The pre-treatment of the plant material with SC CO2 before an ultrasound-assisted extraction or the decrease of a particle size used for ultrasound-assisted extraction of Aloe vera has led to the decrease of maximum useful work and exergy loss. Unlike, pre-treatment with SC CO2 followed by ultrasound-assisted extraction increased the exergy loss when bay was used as the plant material.
PB  - Association of the Chemical Engineers of Serbia
T2  - Chemical Industry & Chemical Engineering Quarterly
T1  - The analysis of different processes of extraction: yield of extracts obtained from Aloe vera (Aloe barbadensis Miller) and sweet bay (Laurus nobilis L.) and the exergy analysis of applied processes
EP  - 278
IS  - 4
SP  - 271
VL  - 15
DO  - 10.2298/CICEQ0904271I
ER  - 

@article{
author = "Ivanović, Jasna and Žižović, Irena and Petrović, Slobodan and Skala, Dejan",
year = "2009",
abstract = "The present study was aimed to investigate and compare the efficiency of different methods for the isolation extract from a plant material. Extracts from dried leaves of Aloe vera (A. barbadensis Mill.) and Sweet Bay (Laurus nobilis L.) were obtained applying the following techniques: supercritical carbon dioxide (SC CO2) extraction at 30 MPa and 100°C, a combined ultrasonic extraction and pre-treatment using SC CO2 (US-SCCO2), and a conventional ultrasonic extraction (US) with 96% ethanol. US-SCCO2 resulted in much higher yields of extracts of aloe and bay compared to SC CO2 extraction. Determined extract's yield was used for calculating the maximum useful work and exergy loss as a measure of irreversibility of the extraction process. Calculated maximum useful work per 1 kg of the extract was ranged from 0.7 to 226 kJ while estimated values of the exergy loss were from 48 to 416 kJ per 1 kg of the extract. The maximum useful work and exergy loss have the largest value for SCE much more than for other processes of extraction (US and US-SCCO2). The pre-treatment of the plant material with SC CO2 before an ultrasound-assisted extraction or the decrease of a particle size used for ultrasound-assisted extraction of Aloe vera has led to the decrease of maximum useful work and exergy loss. Unlike, pre-treatment with SC CO2 followed by ultrasound-assisted extraction increased the exergy loss when bay was used as the plant material.",
publisher = "Association of the Chemical Engineers of Serbia",
journal = "Chemical Industry & Chemical Engineering Quarterly",
title = "The analysis of different processes of extraction: yield of extracts obtained from Aloe vera (Aloe barbadensis Miller) and sweet bay (Laurus nobilis L.) and the exergy analysis of applied processes",
pages = "278-271",
number = "4",
volume = "15",
doi = "10.2298/CICEQ0904271I"
}

Ivanović, J., Žižović, I., Petrović, S.,& Skala, D.. (2009). The analysis of different processes of extraction: yield of extracts obtained from Aloe vera (Aloe barbadensis Miller) and sweet bay (Laurus nobilis L.) and the exergy analysis of applied processes. in Chemical Industry & Chemical Engineering Quarterly
Association of the Chemical Engineers of Serbia., 15(4), 271-278.
https://doi.org/10.2298/CICEQ0904271I

Ivanović J, Žižović I, Petrović S, Skala D. The analysis of different processes of extraction: yield of extracts obtained from Aloe vera (Aloe barbadensis Miller) and sweet bay (Laurus nobilis L.) and the exergy analysis of applied processes. in Chemical Industry & Chemical Engineering Quarterly. 2009;15(4):271-278.
doi:10.2298/CICEQ0904271I .

Ivanović, Jasna, Žižović, Irena, Petrović, Slobodan, Skala, Dejan, "The analysis of different processes of extraction: yield of extracts obtained from Aloe vera (Aloe barbadensis Miller) and sweet bay (Laurus nobilis L.) and the exergy analysis of applied processes" in Chemical Industry & Chemical Engineering Quarterly, 15, no. 4 (2009):271-278,
https://doi.org/10.2298/CICEQ0904271I . .

TY  - JOUR
AU  - Glišić, Sandra
AU  - Skala, Dejan
PY  - 2009
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/1449
AB  - Almost complete methanolysis of triglycerides is usually not enough to fulfil the strict standards of biodiesel quality. A key step in this process is neutralization of alkali (catalyst) followed by the washing procedure necessary for removing different impurities such as traces of catalyst and methanol and removal of soaps and glycerol from esters phase. The washing with hot water is still widely used in many industrial units for the biodiesel production. In this study, different procedures of biodiesel washing using hot water were investigated. The orto-phosphoric acid was suggested as the best compound for alkali catalyst (sodium hydroxide) neutralization. The main goal of the performed analysis was to minimize the water usage in the washing-neutralization step during the biodiesel production. Such solution would make the process of biodiesel synthesis more economical taking into account the decrease of energy consumed for evaporation of water during the final product purification, as well as more acceptable procedure related to the impact on environment (minimal waste water release). Results of the performed simulation of the washing process supported by original experimental data suggested that neutralization after the optimized washing process of the methyl ester layer could be the best solution. The proposed washing procedure significantly decreases the amount of waste water giving at the same time the desired purity of final products (biodiesel and glycerol). The simulation of the process was performed using ASPEN plus software supported by ELCANTREL and UNIQUAC procedure of required properties calculation.
PB  - Association of the Chemical Engineers of Serbia
T2  - Chemical Industry & Chemical Engineering Quarterly
T1  - Design and optimization of purification procedure for biodiesel washing
EP  - 168
IS  - 3
SP  - 159
VL  - 15
DO  - 10.2298/CICEQ0903159G
ER  - 

@article{
author = "Glišić, Sandra and Skala, Dejan",
year = "2009",
abstract = "Almost complete methanolysis of triglycerides is usually not enough to fulfil the strict standards of biodiesel quality. A key step in this process is neutralization of alkali (catalyst) followed by the washing procedure necessary for removing different impurities such as traces of catalyst and methanol and removal of soaps and glycerol from esters phase. The washing with hot water is still widely used in many industrial units for the biodiesel production. In this study, different procedures of biodiesel washing using hot water were investigated. The orto-phosphoric acid was suggested as the best compound for alkali catalyst (sodium hydroxide) neutralization. The main goal of the performed analysis was to minimize the water usage in the washing-neutralization step during the biodiesel production. Such solution would make the process of biodiesel synthesis more economical taking into account the decrease of energy consumed for evaporation of water during the final product purification, as well as more acceptable procedure related to the impact on environment (minimal waste water release). Results of the performed simulation of the washing process supported by original experimental data suggested that neutralization after the optimized washing process of the methyl ester layer could be the best solution. The proposed washing procedure significantly decreases the amount of waste water giving at the same time the desired purity of final products (biodiesel and glycerol). The simulation of the process was performed using ASPEN plus software supported by ELCANTREL and UNIQUAC procedure of required properties calculation.",
publisher = "Association of the Chemical Engineers of Serbia",
journal = "Chemical Industry & Chemical Engineering Quarterly",
title = "Design and optimization of purification procedure for biodiesel washing",
pages = "168-159",
number = "3",
volume = "15",
doi = "10.2298/CICEQ0903159G"
}

Glišić, S.,& Skala, D.. (2009). Design and optimization of purification procedure for biodiesel washing. in Chemical Industry & Chemical Engineering Quarterly
Association of the Chemical Engineers of Serbia., 15(3), 159-168.
https://doi.org/10.2298/CICEQ0903159G

Glišić S, Skala D. Design and optimization of purification procedure for biodiesel washing. in Chemical Industry & Chemical Engineering Quarterly. 2009;15(3):159-168.
doi:10.2298/CICEQ0903159G .

Glišić, Sandra, Skala, Dejan, "Design and optimization of purification procedure for biodiesel washing" in Chemical Industry & Chemical Engineering Quarterly, 15, no. 3 (2009):159-168,
https://doi.org/10.2298/CICEQ0903159G . .

TY  - JOUR
AU  - Glišić, Sandra
AU  - Lukić, Ivana
AU  - Skala, Dejan
PY  - 2009
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/1419
AB  - Analysis of several different schemes for industrial FAME production at higher pressure and temperature (catalytic or non-catalytic synthesis) was realized with the aim to find the best route to reduce the energy consumption (EC) and to improve the life cycle energy efficiency. Obtained results indicated that the EC (MJ/kg FAME) mainly depends on degree of conversion of triglycerides being almost 25% smaller if degree of conversion increase from 97 mass% to complete conversion. Further significant decrease of EC might be obtained at subcritical conditions but only after substantial decrease of methanol to oil molar ratio (from 42 to 15) which requires use of appropriate catalyst. On account of that, the kinetics of heterogeneous catalyzed methanolysis of triglycerides was analyzed using data published in literature (CaO) as well as own experimental data (K2CO3/Al-O-Si) with a goal to obtain reliable kinetic rate constant which might be used for process simulation. This study shows that if heterogeneous process of biodiesel synthesis is realized at subcritical conditions then further decrease of EC is possible.
PB  - Elsevier Sci Ltd, Oxford
T2  - Bioresource Technology
T1  - Biodiesel synthesis at high pressure and temperature: Analysis of energy consumption on industrial scale
EP  - 6354
IS  - 24
SP  - 6347
VL  - 100
DO  - 10.1016/j.biortech.2009.07.024
ER  - 

@article{
author = "Glišić, Sandra and Lukić, Ivana and Skala, Dejan",
year = "2009",
abstract = "Analysis of several different schemes for industrial FAME production at higher pressure and temperature (catalytic or non-catalytic synthesis) was realized with the aim to find the best route to reduce the energy consumption (EC) and to improve the life cycle energy efficiency. Obtained results indicated that the EC (MJ/kg FAME) mainly depends on degree of conversion of triglycerides being almost 25% smaller if degree of conversion increase from 97 mass% to complete conversion. Further significant decrease of EC might be obtained at subcritical conditions but only after substantial decrease of methanol to oil molar ratio (from 42 to 15) which requires use of appropriate catalyst. On account of that, the kinetics of heterogeneous catalyzed methanolysis of triglycerides was analyzed using data published in literature (CaO) as well as own experimental data (K2CO3/Al-O-Si) with a goal to obtain reliable kinetic rate constant which might be used for process simulation. This study shows that if heterogeneous process of biodiesel synthesis is realized at subcritical conditions then further decrease of EC is possible.",
publisher = "Elsevier Sci Ltd, Oxford",
journal = "Bioresource Technology",
title = "Biodiesel synthesis at high pressure and temperature: Analysis of energy consumption on industrial scale",
pages = "6354-6347",
number = "24",
volume = "100",
doi = "10.1016/j.biortech.2009.07.024"
}

Glišić, S., Lukić, I.,& Skala, D.. (2009). Biodiesel synthesis at high pressure and temperature: Analysis of energy consumption on industrial scale. in Bioresource Technology
Elsevier Sci Ltd, Oxford., 100(24), 6347-6354.
https://doi.org/10.1016/j.biortech.2009.07.024

Glišić S, Lukić I, Skala D. Biodiesel synthesis at high pressure and temperature: Analysis of energy consumption on industrial scale. in Bioresource Technology. 2009;100(24):6347-6354.
doi:10.1016/j.biortech.2009.07.024 .

Glišić, Sandra, Lukić, Ivana, Skala, Dejan, "Biodiesel synthesis at high pressure and temperature: Analysis of energy consumption on industrial scale" in Bioresource Technology, 100, no. 24 (2009):6347-6354,
https://doi.org/10.1016/j.biortech.2009.07.024 . .

TY  - JOUR
AU  - Stamenić, Marko
AU  - Žižović, Irena
AU  - Orlović, Aleksandar
AU  - Skala, Dejan
PY  - 2008
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/1243
AB  - This article reports the achievements of the micro-scale (secretory-structure-scale) mathematical modelling of essential oil isolation by supercritical carbon dioxide. Some new experimental and modelling results are presented. The improved model for the supercritical fluid extraction from the glandular trichomes (peltate glands) is introduced. According to the behavior of plant secretory structures during the extraction as well as according to the modelling results, plant material was classified according to the dominant resistance to mass transfer during the extraction process. External mass transfer was the rate limiting step in the extraction from plants with secretory ducts and secretory cavities of citrus family. In the case of extraction from secretory cells, internal diffusion was the rate limiting step. In the extraction from glandular trichomes, external mass transfer, as well as diffusion through the gland membrane influenced the process.
PB  - Elsevier, Amsterdam
T2  - Journal of Supercritical Fluids
T1  - Mathematical modelling of essential oil SFE on the micro-scale - Classification of plant material
EP  - 292
IS  - 3
SP  - 285
VL  - 46
DO  - 10.1016/j.supflu.2008.03.007
ER  - 

@article{
author = "Stamenić, Marko and Žižović, Irena and Orlović, Aleksandar and Skala, Dejan",
year = "2008",
abstract = "This article reports the achievements of the micro-scale (secretory-structure-scale) mathematical modelling of essential oil isolation by supercritical carbon dioxide. Some new experimental and modelling results are presented. The improved model for the supercritical fluid extraction from the glandular trichomes (peltate glands) is introduced. According to the behavior of plant secretory structures during the extraction as well as according to the modelling results, plant material was classified according to the dominant resistance to mass transfer during the extraction process. External mass transfer was the rate limiting step in the extraction from plants with secretory ducts and secretory cavities of citrus family. In the case of extraction from secretory cells, internal diffusion was the rate limiting step. In the extraction from glandular trichomes, external mass transfer, as well as diffusion through the gland membrane influenced the process.",
publisher = "Elsevier, Amsterdam",
journal = "Journal of Supercritical Fluids",
title = "Mathematical modelling of essential oil SFE on the micro-scale - Classification of plant material",
pages = "292-285",
number = "3",
volume = "46",
doi = "10.1016/j.supflu.2008.03.007"
}

Stamenić, M., Žižović, I., Orlović, A.,& Skala, D.. (2008). Mathematical modelling of essential oil SFE on the micro-scale - Classification of plant material. in Journal of Supercritical Fluids
Elsevier, Amsterdam., 46(3), 285-292.
https://doi.org/10.1016/j.supflu.2008.03.007

Stamenić M, Žižović I, Orlović A, Skala D. Mathematical modelling of essential oil SFE on the micro-scale - Classification of plant material. in Journal of Supercritical Fluids. 2008;46(3):285-292.
doi:10.1016/j.supflu.2008.03.007 .

Stamenić, Marko, Žižović, Irena, Orlović, Aleksandar, Skala, Dejan, "Mathematical modelling of essential oil SFE on the micro-scale - Classification of plant material" in Journal of Supercritical Fluids, 46, no. 3 (2008):285-292,
https://doi.org/10.1016/j.supflu.2008.03.007 . .

TY  - JOUR
AU  - Mišić, Dušan
AU  - Žižović, Irena
AU  - Stamenić, Marko
AU  - Ašanin, Ružica
AU  - Ristić, Mihailo S.
AU  - Petrović, Slobodan
AU  - Skala, Dejan
PY  - 2008
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/1225
PB  - Elsevier, Amsterdam
T2  - Biochemical Engineering Journal
T1  - Antimicrobial activity of celery fruit isolates and SFE process modeling
EP  - 152
IS  - 2
SP  - 148
VL  - 42
DO  - 10.1016/j.bej.2008.06.008
ER  - 

@article{
author = "Mišić, Dušan and Žižović, Irena and Stamenić, Marko and Ašanin, Ružica and Ristić, Mihailo S. and Petrović, Slobodan and Skala, Dejan",
year = "2008",
publisher = "Elsevier, Amsterdam",
journal = "Biochemical Engineering Journal",
title = "Antimicrobial activity of celery fruit isolates and SFE process modeling",
pages = "152-148",
number = "2",
volume = "42",
doi = "10.1016/j.bej.2008.06.008"
}

Mišić, D., Žižović, I., Stamenić, M., Ašanin, R., Ristić, M. S., Petrović, S.,& Skala, D.. (2008). Antimicrobial activity of celery fruit isolates and SFE process modeling. in Biochemical Engineering Journal
Elsevier, Amsterdam., 42(2), 148-152.
https://doi.org/10.1016/j.bej.2008.06.008

Mišić D, Žižović I, Stamenić M, Ašanin R, Ristić MS, Petrović S, Skala D. Antimicrobial activity of celery fruit isolates and SFE process modeling. in Biochemical Engineering Journal. 2008;42(2):148-152.
doi:10.1016/j.bej.2008.06.008 .

Mišić, Dušan, Žižović, Irena, Stamenić, Marko, Ašanin, Ružica, Ristić, Mihailo S., Petrović, Slobodan, Skala, Dejan, "Antimicrobial activity of celery fruit isolates and SFE process modeling" in Biochemical Engineering Journal, 42, no. 2 (2008):148-152,
https://doi.org/10.1016/j.bej.2008.06.008 . .

TY  - JOUR
AU  - Žižović, Irena
AU  - Stamenić, Marko
AU  - Orlović, Aleksandar
AU  - Skala, Dejan
PY  - 2007
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/1118
AB  - In this study, the supercritical carbon dioxide extraction of essential oils from plants which contain secretory ducts as essential oil reservoirs was investigated and modelled. Supercritical carbon dioxide extraction of essential oils from Asteraceae family species, marigold and chamomile, indicated that particle size had no significant influence on the extraction rate in two outermost cases: fine milled plant material and plant material cut to particle length of 5 mm. This confirmed previously reported phenomenon that in some cases particle size had no influence on the rate of supercritical extraction process. In order to explain this behavior, the mathematical model which took into consideration the phenomena occurring on the secretory duct scale, was developed and applied to simulate experimental data of marigold and chamomile supercritical carbon dioxide extraction. Proposed model was also applied to the literature experimental data of fennel fruit supercritical fluid extraction where the same phenomenon had been observed. To obtain information regarding secretory structure, scanning electron microscopy investigation of the plant material was performed. Very good agreement of the model results and experimental data in the case of different plant species, extraction conditions and particle sizes, confirmed the basic hypothesis of the model.
PB  - Elsevier, Amsterdam
T2  - Journal of Supercritical Fluids
T1  - Supercritical carbon dioxide extraction of essential oils from plants with secretory ducts: Mathematical modelling on the micro-scale
EP  - 346
IS  - 3
SP  - 338
VL  - 39
DO  - 10.1016/j.supflu.2006.03.009
ER  - 

@article{
author = "Žižović, Irena and Stamenić, Marko and Orlović, Aleksandar and Skala, Dejan",
year = "2007",
abstract = "In this study, the supercritical carbon dioxide extraction of essential oils from plants which contain secretory ducts as essential oil reservoirs was investigated and modelled. Supercritical carbon dioxide extraction of essential oils from Asteraceae family species, marigold and chamomile, indicated that particle size had no significant influence on the extraction rate in two outermost cases: fine milled plant material and plant material cut to particle length of 5 mm. This confirmed previously reported phenomenon that in some cases particle size had no influence on the rate of supercritical extraction process. In order to explain this behavior, the mathematical model which took into consideration the phenomena occurring on the secretory duct scale, was developed and applied to simulate experimental data of marigold and chamomile supercritical carbon dioxide extraction. Proposed model was also applied to the literature experimental data of fennel fruit supercritical fluid extraction where the same phenomenon had been observed. To obtain information regarding secretory structure, scanning electron microscopy investigation of the plant material was performed. Very good agreement of the model results and experimental data in the case of different plant species, extraction conditions and particle sizes, confirmed the basic hypothesis of the model.",
publisher = "Elsevier, Amsterdam",
journal = "Journal of Supercritical Fluids",
title = "Supercritical carbon dioxide extraction of essential oils from plants with secretory ducts: Mathematical modelling on the micro-scale",
pages = "346-338",
number = "3",
volume = "39",
doi = "10.1016/j.supflu.2006.03.009"
}

Žižović, I., Stamenić, M., Orlović, A.,& Skala, D.. (2007). Supercritical carbon dioxide extraction of essential oils from plants with secretory ducts: Mathematical modelling on the micro-scale. in Journal of Supercritical Fluids
Elsevier, Amsterdam., 39(3), 338-346.
https://doi.org/10.1016/j.supflu.2006.03.009

Žižović I, Stamenić M, Orlović A, Skala D. Supercritical carbon dioxide extraction of essential oils from plants with secretory ducts: Mathematical modelling on the micro-scale. in Journal of Supercritical Fluids. 2007;39(3):338-346.
doi:10.1016/j.supflu.2006.03.009 .

Žižović, Irena, Stamenić, Marko, Orlović, Aleksandar, Skala, Dejan, "Supercritical carbon dioxide extraction of essential oils from plants with secretory ducts: Mathematical modelling on the micro-scale" in Journal of Supercritical Fluids, 39, no. 3 (2007):338-346,
https://doi.org/10.1016/j.supflu.2006.03.009 . .

TY  - JOUR
AU  - Žižović, Irena
AU  - Stamenić, Marko
AU  - Ivanović, Jasna
AU  - Orlović, Aleksandar
AU  - Ristić, Mihailo S.
AU  - Đorđević, Sofija
AU  - Petrović, Slobodan
AU  - Skala, Dejan
PY  - 2007
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/1136
AB  - Supercritical carbon dioxide extraction of sesquiterpenes from valerian root was investigated. Extractions from cultivar Arterner zuctung and two wild grown valerian subspecies were performed. The influence of extraction conditions on extraction yield and chemical composition of obtained extracts was investigated at temperatures from 40 degrees C to 50 degrees C and pressures from 10 MPa to 20 MPa. Chemical composition of obtained extracts was analyzed by GC/FID and GC/MS methods. The influence of particle size on extraction process was investigated at 40 degrees C and 10 MPa. The major constituents of supercritical extracts were valerianol, valerenal, bornyl acetate and kessanyl acetate. Optimal extraction conditions for the cyclopentanoid sesquiterepenes isolation, referred to the content of cyclopentanoid sesquiterpenes in extract, were found to be 50 degrees C and 15 MPa. Extract obtained from the cultivar was characterized by the higher content of cyclopentanoid sesquiterpenes, as well as valerenal comparing to extracts from wild grown species. At 40 degrees C and 20 MPa 19.6% of cyclopentanoid sequiterpenes isolated with methanol can be extracted. At 40 degrees C and 10 MPa, 17.4% of cyclopentanoid sequiterpenes isolated with methanol can be extracted. However, the extract obtained with methanol was characterized by the high content (42.51 %) of unwanted isovaleric as well as by the lower content of cyclopentanoid sequiterpenes than the extracts obtained with supercritical carbon dioxide. The process of supercritical extraction was influenced by particle size. In order to simulate the process, mathematical model on the secretory structure scale was derived. Results of the model showed good agreement with the experimental data.
PB  - Elsevier Science Bv, Amsterdam
T2  - Journal of Supercritical Fluids
T1  - Supercritical carbon dioxide extraction of sesquiterpenes from valerian root
EP  - 258
IS  - 2
SP  - 249
VL  - 43
DO  - 10.1016/j.supflu.2007.05.007
ER  - 

@article{
author = "Žižović, Irena and Stamenić, Marko and Ivanović, Jasna and Orlović, Aleksandar and Ristić, Mihailo S. and Đorđević, Sofija and Petrović, Slobodan and Skala, Dejan",
year = "2007",
abstract = "Supercritical carbon dioxide extraction of sesquiterpenes from valerian root was investigated. Extractions from cultivar Arterner zuctung and two wild grown valerian subspecies were performed. The influence of extraction conditions on extraction yield and chemical composition of obtained extracts was investigated at temperatures from 40 degrees C to 50 degrees C and pressures from 10 MPa to 20 MPa. Chemical composition of obtained extracts was analyzed by GC/FID and GC/MS methods. The influence of particle size on extraction process was investigated at 40 degrees C and 10 MPa. The major constituents of supercritical extracts were valerianol, valerenal, bornyl acetate and kessanyl acetate. Optimal extraction conditions for the cyclopentanoid sesquiterepenes isolation, referred to the content of cyclopentanoid sesquiterpenes in extract, were found to be 50 degrees C and 15 MPa. Extract obtained from the cultivar was characterized by the higher content of cyclopentanoid sesquiterpenes, as well as valerenal comparing to extracts from wild grown species. At 40 degrees C and 20 MPa 19.6% of cyclopentanoid sequiterpenes isolated with methanol can be extracted. At 40 degrees C and 10 MPa, 17.4% of cyclopentanoid sequiterpenes isolated with methanol can be extracted. However, the extract obtained with methanol was characterized by the high content (42.51 %) of unwanted isovaleric as well as by the lower content of cyclopentanoid sequiterpenes than the extracts obtained with supercritical carbon dioxide. The process of supercritical extraction was influenced by particle size. In order to simulate the process, mathematical model on the secretory structure scale was derived. Results of the model showed good agreement with the experimental data.",
publisher = "Elsevier Science Bv, Amsterdam",
journal = "Journal of Supercritical Fluids",
title = "Supercritical carbon dioxide extraction of sesquiterpenes from valerian root",
pages = "258-249",
number = "2",
volume = "43",
doi = "10.1016/j.supflu.2007.05.007"
}

Žižović, I., Stamenić, M., Ivanović, J., Orlović, A., Ristić, M. S., Đorđević, S., Petrović, S.,& Skala, D.. (2007). Supercritical carbon dioxide extraction of sesquiterpenes from valerian root. in Journal of Supercritical Fluids
Elsevier Science Bv, Amsterdam., 43(2), 249-258.
https://doi.org/10.1016/j.supflu.2007.05.007

Žižović I, Stamenić M, Ivanović J, Orlović A, Ristić MS, Đorđević S, Petrović S, Skala D. Supercritical carbon dioxide extraction of sesquiterpenes from valerian root. in Journal of Supercritical Fluids. 2007;43(2):249-258.
doi:10.1016/j.supflu.2007.05.007 .

Žižović, Irena, Stamenić, Marko, Ivanović, Jasna, Orlović, Aleksandar, Ristić, Mihailo S., Đorđević, Sofija, Petrović, Slobodan, Skala, Dejan, "Supercritical carbon dioxide extraction of sesquiterpenes from valerian root" in Journal of Supercritical Fluids, 43, no. 2 (2007):249-258,
https://doi.org/10.1016/j.supflu.2007.05.007 . .

TY  - JOUR
AU  - Glišić, Sandra
AU  - Mišić, Dušan
AU  - Stamenić, Marko
AU  - Žižović, Irena
AU  - Asanin, Ružica
AU  - Skala, Dejan
PY  - 2007
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/1167
AB  - Isolation of carrot fruit (Daucus carrota L., cultivar "Chanteney") essential oil by supercritical carbon dioxide was investigated from the pretreatment of herbaceous matrix and extraction conditions to the chemical composition of obtained extract and its antimicrobial activity. The qualitative and quantitative analyses of the supercritical extract, as well as of the essential oil obtained by hydrodistillation, were done by GC/FID and GC/MS methods. Antimicrobial properties of both samples were investigated against ten species of microorganisms. Experimental results showed that the particle size had no influence on the extraction process. The highest yield was obtained at 40 degrees C and 10 MPa. The main component of the supercritical extract, as well as of the essential oil was carotol. The supercritical extract was characterized by the presence of heavier molecular weight compounds, while some lighter compounds, e.g. pinenes, were not detected. The supercritical extract and the essential oil were the most effective against Gram-positive bacteria.
PB  - Elsevier Sci Ltd, Oxford
T2  - Food Chemistry
T1  - Supercritical carbon dioxide extraction of carrot fruit essential oil: Chemical composition and antimicrobial activity
EP  - 352
IS  - 1
SP  - 346
VL  - 105
DO  - 10.1016/j.foodchem.2006.11.062
ER  - 

@article{
author = "Glišić, Sandra and Mišić, Dušan and Stamenić, Marko and Žižović, Irena and Asanin, Ružica and Skala, Dejan",
year = "2007",
abstract = "Isolation of carrot fruit (Daucus carrota L., cultivar "Chanteney") essential oil by supercritical carbon dioxide was investigated from the pretreatment of herbaceous matrix and extraction conditions to the chemical composition of obtained extract and its antimicrobial activity. The qualitative and quantitative analyses of the supercritical extract, as well as of the essential oil obtained by hydrodistillation, were done by GC/FID and GC/MS methods. Antimicrobial properties of both samples were investigated against ten species of microorganisms. Experimental results showed that the particle size had no influence on the extraction process. The highest yield was obtained at 40 degrees C and 10 MPa. The main component of the supercritical extract, as well as of the essential oil was carotol. The supercritical extract was characterized by the presence of heavier molecular weight compounds, while some lighter compounds, e.g. pinenes, were not detected. The supercritical extract and the essential oil were the most effective against Gram-positive bacteria.",
publisher = "Elsevier Sci Ltd, Oxford",
journal = "Food Chemistry",
title = "Supercritical carbon dioxide extraction of carrot fruit essential oil: Chemical composition and antimicrobial activity",
pages = "352-346",
number = "1",
volume = "105",
doi = "10.1016/j.foodchem.2006.11.062"
}

Glišić, S., Mišić, D., Stamenić, M., Žižović, I., Asanin, R.,& Skala, D.. (2007). Supercritical carbon dioxide extraction of carrot fruit essential oil: Chemical composition and antimicrobial activity. in Food Chemistry
Elsevier Sci Ltd, Oxford., 105(1), 346-352.
https://doi.org/10.1016/j.foodchem.2006.11.062

Glišić S, Mišić D, Stamenić M, Žižović I, Asanin R, Skala D. Supercritical carbon dioxide extraction of carrot fruit essential oil: Chemical composition and antimicrobial activity. in Food Chemistry. 2007;105(1):346-352.
doi:10.1016/j.foodchem.2006.11.062 .

Glišić, Sandra, Mišić, Dušan, Stamenić, Marko, Žižović, Irena, Asanin, Ružica, Skala, Dejan, "Supercritical carbon dioxide extraction of carrot fruit essential oil: Chemical composition and antimicrobial activity" in Food Chemistry, 105, no. 1 (2007):346-352,
https://doi.org/10.1016/j.foodchem.2006.11.062 . .