TY  - JOUR
AU  - Laban, Bojana B.
AU  - Lazarević-Pašti, Tamara
AU  - Veljović, Đorđe
AU  - Marković, Mirjana
AU  - Klekotka, Urszula
PY  - 2023
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/6222
AB  - The silver and gold L-methionine capped nanoparticles (Ag and Au @LM NPs) were analyzed as prospective acetylcholinesterase (AChE) inhibitors to test their potential in the treatment of cognitive impairment in depression and Alzheimer's disease. The stability of NPs, and their ability to inhibit AChE were studied by UV-Vis and FTIR spectrophotometry. At the same time, TEM and SEM measurements, DLS, and zeta potential measurements were employed in the structural characterization of NPs. Nearly spherical, negatively charged Ag and Au @LM NPs, with 17 nm and 31 nm in diameter, respectively, showed moderate inhibitory potential toward AChE in the given frame of investigated concentrations. For both NPs IC50 is not reached. Furthermore, the adsorption of enzyme molecules on the surface of Ag and Au @LM NPs was demonstrated. Hence, our assumption is that inhibition of AChE is caused by blockage of the enzyme‘s active site due to the steric hindrance of NPs.
PB  - John Wiley and Sons Inc.
T2  - European Journal of Inorganic Chemistry
T1  - Methionine Capped Nanoparticles as Acetylcholinesterase Inhibitors
SP  - e202200754
DO  - 10.1002/ejic.202200754
ER  - 

@article{
author = "Laban, Bojana B. and Lazarević-Pašti, Tamara and Veljović, Đorđe and Marković, Mirjana and Klekotka, Urszula",
year = "2023",
abstract = "The silver and gold L-methionine capped nanoparticles (Ag and Au @LM NPs) were analyzed as prospective acetylcholinesterase (AChE) inhibitors to test their potential in the treatment of cognitive impairment in depression and Alzheimer's disease. The stability of NPs, and their ability to inhibit AChE were studied by UV-Vis and FTIR spectrophotometry. At the same time, TEM and SEM measurements, DLS, and zeta potential measurements were employed in the structural characterization of NPs. Nearly spherical, negatively charged Ag and Au @LM NPs, with 17 nm and 31 nm in diameter, respectively, showed moderate inhibitory potential toward AChE in the given frame of investigated concentrations. For both NPs IC50 is not reached. Furthermore, the adsorption of enzyme molecules on the surface of Ag and Au @LM NPs was demonstrated. Hence, our assumption is that inhibition of AChE is caused by blockage of the enzyme‘s active site due to the steric hindrance of NPs.",
publisher = "John Wiley and Sons Inc.",
journal = "European Journal of Inorganic Chemistry",
title = "Methionine Capped Nanoparticles as Acetylcholinesterase Inhibitors",
pages = "e202200754",
doi = "10.1002/ejic.202200754"
}

Laban, B. B., Lazarević-Pašti, T., Veljović, Đ., Marković, M.,& Klekotka, U.. (2023). Methionine Capped Nanoparticles as Acetylcholinesterase Inhibitors. in European Journal of Inorganic Chemistry
John Wiley and Sons Inc.., e202200754.
https://doi.org/10.1002/ejic.202200754

Laban BB, Lazarević-Pašti T, Veljović Đ, Marković M, Klekotka U. Methionine Capped Nanoparticles as Acetylcholinesterase Inhibitors. in European Journal of Inorganic Chemistry. 2023;:e202200754.
doi:10.1002/ejic.202200754 .

Laban, Bojana B., Lazarević-Pašti, Tamara, Veljović, Đorđe, Marković, Mirjana, Klekotka, Urszula, "Methionine Capped Nanoparticles as Acetylcholinesterase Inhibitors" in European Journal of Inorganic Chemistry (2023):e202200754,
https://doi.org/10.1002/ejic.202200754 . .

TY  - JOUR
AU  - Petković, Branka B.
AU  - Kostić, Marija
AU  - Samaržija-Jovanović, Suzana
AU  - Ivanović, Aleksandra
AU  - Laban, Bojana
AU  - Veljović, Đorđe
AU  - Stanković, Dalibor M.
PY  - 2022
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/5283
AB  - Urea-formaldehyde resin (UF) is primarily used as an adhesive applied in the wood composites industry. In this work, we found that this resin modified with metal compounds could be a good starting point to produce high-performance electrode material applied for the construction of electrochemical sensor for important antioxidant, such as caffeic acids (CA). The conductivity of carbon paste electrodes (CPE) modified by materials produced by thermolysis of in situ synthesized urea formaldehyde resins with Fe(III) and Ti(IV) compounds (mixed metal compounds and individually) were examined. For comparison, pure CPE and CPE modified with material produced from the physical mixture of UF resins and metal compounds in the same combinations were also electrochemically characterized by impedance spectroscopy and cyclic voltammetry. The most conductive material, which consists of a combination of metal oxide particles in situ synthesized with UF (SynFe+Ti/UF-TP@CPE), was used as a CPE modifier and proved itself in sensitive differential pulse voltammetric determination of caffeic acid at a wide working range of 0.5-100 and limit of detection of 0.046 μM. The proposed electrode was successfully applied for the determination of the content of CA in spiked urine samples and the estimation of total phenol content, based on CA equivalents, of honey, liqueur and juice samples.
PB  - Electrochemical Science Group
T2  - International Journal of Electrochemical Science
T1  - An Efficient Electrochemical Sensing of Caffeic Acid at Thermolysis Prepared Urea-formaldehyde Resin Modified with Fe(III) and Ti(IV) Oxide Particles
SP  - 221214
VL  - 17
DO  - 10.20964/2022.12.04
ER  - 

@article{
author = "Petković, Branka B. and Kostić, Marija and Samaržija-Jovanović, Suzana and Ivanović, Aleksandra and Laban, Bojana and Veljović, Đorđe and Stanković, Dalibor M.",
year = "2022",
abstract = "Urea-formaldehyde resin (UF) is primarily used as an adhesive applied in the wood composites industry. In this work, we found that this resin modified with metal compounds could be a good starting point to produce high-performance electrode material applied for the construction of electrochemical sensor for important antioxidant, such as caffeic acids (CA). The conductivity of carbon paste electrodes (CPE) modified by materials produced by thermolysis of in situ synthesized urea formaldehyde resins with Fe(III) and Ti(IV) compounds (mixed metal compounds and individually) were examined. For comparison, pure CPE and CPE modified with material produced from the physical mixture of UF resins and metal compounds in the same combinations were also electrochemically characterized by impedance spectroscopy and cyclic voltammetry. The most conductive material, which consists of a combination of metal oxide particles in situ synthesized with UF (SynFe+Ti/UF-TP@CPE), was used as a CPE modifier and proved itself in sensitive differential pulse voltammetric determination of caffeic acid at a wide working range of 0.5-100 and limit of detection of 0.046 μM. The proposed electrode was successfully applied for the determination of the content of CA in spiked urine samples and the estimation of total phenol content, based on CA equivalents, of honey, liqueur and juice samples.",
publisher = "Electrochemical Science Group",
journal = "International Journal of Electrochemical Science",
title = "An Efficient Electrochemical Sensing of Caffeic Acid at Thermolysis Prepared Urea-formaldehyde Resin Modified with Fe(III) and Ti(IV) Oxide Particles",
pages = "221214",
volume = "17",
doi = "10.20964/2022.12.04"
}

Petković, B. B., Kostić, M., Samaržija-Jovanović, S., Ivanović, A., Laban, B., Veljović, Đ.,& Stanković, D. M.. (2022). An Efficient Electrochemical Sensing of Caffeic Acid at Thermolysis Prepared Urea-formaldehyde Resin Modified with Fe(III) and Ti(IV) Oxide Particles. in International Journal of Electrochemical Science
Electrochemical Science Group., 17, 221214.
https://doi.org/10.20964/2022.12.04

Petković BB, Kostić M, Samaržija-Jovanović S, Ivanović A, Laban B, Veljović Đ, Stanković DM. An Efficient Electrochemical Sensing of Caffeic Acid at Thermolysis Prepared Urea-formaldehyde Resin Modified with Fe(III) and Ti(IV) Oxide Particles. in International Journal of Electrochemical Science. 2022;17:221214.
doi:10.20964/2022.12.04 .

Petković, Branka B., Kostić, Marija, Samaržija-Jovanović, Suzana, Ivanović, Aleksandra, Laban, Bojana, Veljović, Đorđe, Stanković, Dalibor M., "An Efficient Electrochemical Sensing of Caffeic Acid at Thermolysis Prepared Urea-formaldehyde Resin Modified with Fe(III) and Ti(IV) Oxide Particles" in International Journal of Electrochemical Science, 17 (2022):221214,
https://doi.org/10.20964/2022.12.04 . .