TY  - JOUR
AU  - Sulaeva, Irina
AU  - Hettegger, Hubert
AU  - Bergen, Anna
AU  - Rohrer, Christian
AU  - Kostić, Mirjana
AU  - Konnerth, Johannes
AU  - Rosenau, Thomas
AU  - Potthast, Antje
PY  - 2020
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4467
AB  - Bacterial cellulose (BC) hydrogels are among the most efficient materials already being used for the treatment of complex wounds. The moist environment provided by the BC dressing is a key feature assuring efficient wound recovery. Improving the dressings' moisture-holding ability facilitates its application and leads to an economically preferable extended wear time. To produce materials with reduced moisture loss, BC dressings were impregnated with a secondary hydrophilic component: alginate. The feasibility of an industrial fabrication of this composite was evaluated on pilot scale equipment. It was shown that the procedure can easily be scaled up without significantly increasing the manufacturing time. The resultant composite possessed improved water-retention properties, providing a smooth dressing exchange as demonstrated by a wound-imitating model. The new materials were moreover shown to be compatible with an antimicrobially active compound, which assures their efficiency in the treatment of highly colonized wounds.
PB  - Elsevier, Amsterdam
T2  - Materials Science & Engineering C-Materials for Biological Applications
T1  - Fabrication of bacterial cellulose-based wound dressings with improved performance by impregnation with alginate
VL  - 110
DO  - 10.1016/j.msec.2019.110619
ER  - 

@article{
author = "Sulaeva, Irina and Hettegger, Hubert and Bergen, Anna and Rohrer, Christian and Kostić, Mirjana and Konnerth, Johannes and Rosenau, Thomas and Potthast, Antje",
year = "2020",
abstract = "Bacterial cellulose (BC) hydrogels are among the most efficient materials already being used for the treatment of complex wounds. The moist environment provided by the BC dressing is a key feature assuring efficient wound recovery. Improving the dressings' moisture-holding ability facilitates its application and leads to an economically preferable extended wear time. To produce materials with reduced moisture loss, BC dressings were impregnated with a secondary hydrophilic component: alginate. The feasibility of an industrial fabrication of this composite was evaluated on pilot scale equipment. It was shown that the procedure can easily be scaled up without significantly increasing the manufacturing time. The resultant composite possessed improved water-retention properties, providing a smooth dressing exchange as demonstrated by a wound-imitating model. The new materials were moreover shown to be compatible with an antimicrobially active compound, which assures their efficiency in the treatment of highly colonized wounds.",
publisher = "Elsevier, Amsterdam",
journal = "Materials Science & Engineering C-Materials for Biological Applications",
title = "Fabrication of bacterial cellulose-based wound dressings with improved performance by impregnation with alginate",
volume = "110",
doi = "10.1016/j.msec.2019.110619"
}

Sulaeva, I., Hettegger, H., Bergen, A., Rohrer, C., Kostić, M., Konnerth, J., Rosenau, T.,& Potthast, A.. (2020). Fabrication of bacterial cellulose-based wound dressings with improved performance by impregnation with alginate. in Materials Science & Engineering C-Materials for Biological Applications
Elsevier, Amsterdam., 110.
https://doi.org/10.1016/j.msec.2019.110619

Sulaeva I, Hettegger H, Bergen A, Rohrer C, Kostić M, Konnerth J, Rosenau T, Potthast A. Fabrication of bacterial cellulose-based wound dressings with improved performance by impregnation with alginate. in Materials Science & Engineering C-Materials for Biological Applications. 2020;110.
doi:10.1016/j.msec.2019.110619 .

Sulaeva, Irina, Hettegger, Hubert, Bergen, Anna, Rohrer, Christian, Kostić, Mirjana, Konnerth, Johannes, Rosenau, Thomas, Potthast, Antje, "Fabrication of bacterial cellulose-based wound dressings with improved performance by impregnation with alginate" in Materials Science & Engineering C-Materials for Biological Applications, 110 (2020),
https://doi.org/10.1016/j.msec.2019.110619 . .