TY  - JOUR
AU  - Božanić, Dušan K.
AU  - Đoković, Vladimir
AU  - Dimitrijević-Branković, Suzana
AU  - Krsmanović, Radenka
AU  - McPherson, Michael
AU  - Nair, P. Sreekumari
AU  - Georges, Michael K.
AU  - Radhakrishnan, Thottackad
PY  - 2011
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/1857
AB  - A sago starch biopolymer with embedded silver nanoparticles has been studied as a material for the prevention of microbial growth. Approximately 8 nm in size, silver nanoparticles have been synthesized by reduction of the silver salt in aqueous solution in the presence of sago starch using sodium borohydride as a reducing agent. The obtained solutions were cast on glass plates to obtain thin supported silver-starch nanocomposite films. The morphology of the nanocomposites was investigated by scanning and transmission electron microscopy. UV-Vis absorption spectroscopy showed that during the film formation a part of the silver nanoparticles has been trapped in the water present in the sample, which enabled their partial oxidation into active Ag(+) species. The oxidation of the silver nanoparticles was confirmed by X-ray photoelectron spectroscopy. The antimicrobial activity tests have shown that the nanocomposite material can be successfully employed to prevent the viability and growth of the common pathogens Staphylococcus aureus, Escherichia coli and Candida albicans.
PB  - Vsp Bv, Leiden
T2  - Journal of Biomaterials Science-Polymer Edition
T1  - Inhibition of Microbial Growth by Silver-Starch Nanocomposite Thin Films
EP  - 2355
IS  - 17
SP  - 2343
VL  - 22
DO  - 10.1163/092050610X539532
ER  - 

@article{
author = "Božanić, Dušan K. and Đoković, Vladimir and Dimitrijević-Branković, Suzana and Krsmanović, Radenka and McPherson, Michael and Nair, P. Sreekumari and Georges, Michael K. and Radhakrishnan, Thottackad",
year = "2011",
abstract = "A sago starch biopolymer with embedded silver nanoparticles has been studied as a material for the prevention of microbial growth. Approximately 8 nm in size, silver nanoparticles have been synthesized by reduction of the silver salt in aqueous solution in the presence of sago starch using sodium borohydride as a reducing agent. The obtained solutions were cast on glass plates to obtain thin supported silver-starch nanocomposite films. The morphology of the nanocomposites was investigated by scanning and transmission electron microscopy. UV-Vis absorption spectroscopy showed that during the film formation a part of the silver nanoparticles has been trapped in the water present in the sample, which enabled their partial oxidation into active Ag(+) species. The oxidation of the silver nanoparticles was confirmed by X-ray photoelectron spectroscopy. The antimicrobial activity tests have shown that the nanocomposite material can be successfully employed to prevent the viability and growth of the common pathogens Staphylococcus aureus, Escherichia coli and Candida albicans.",
publisher = "Vsp Bv, Leiden",
journal = "Journal of Biomaterials Science-Polymer Edition",
title = "Inhibition of Microbial Growth by Silver-Starch Nanocomposite Thin Films",
pages = "2355-2343",
number = "17",
volume = "22",
doi = "10.1163/092050610X539532"
}

Božanić, D. K., Đoković, V., Dimitrijević-Branković, S., Krsmanović, R., McPherson, M., Nair, P. S., Georges, M. K.,& Radhakrishnan, T.. (2011). Inhibition of Microbial Growth by Silver-Starch Nanocomposite Thin Films. in Journal of Biomaterials Science-Polymer Edition
Vsp Bv, Leiden., 22(17), 2343-2355.
https://doi.org/10.1163/092050610X539532

Božanić DK, Đoković V, Dimitrijević-Branković S, Krsmanović R, McPherson M, Nair PS, Georges MK, Radhakrishnan T. Inhibition of Microbial Growth by Silver-Starch Nanocomposite Thin Films. in Journal of Biomaterials Science-Polymer Edition. 2011;22(17):2343-2355.
doi:10.1163/092050610X539532 .

Božanić, Dušan K., Đoković, Vladimir, Dimitrijević-Branković, Suzana, Krsmanović, Radenka, McPherson, Michael, Nair, P. Sreekumari, Georges, Michael K., Radhakrishnan, Thottackad, "Inhibition of Microbial Growth by Silver-Starch Nanocomposite Thin Films" in Journal of Biomaterials Science-Polymer Edition, 22, no. 17 (2011):2343-2355,
https://doi.org/10.1163/092050610X539532 . .

TY  - JOUR
AU  - Tomić, Simonida
AU  - Mićić, Maja M.
AU  - Dobić, Sava N.
AU  - Filipović, Jovanka M.
AU  - Suljovrujić, Edin H.
PY  - 2010
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/1707
AB  - pH- and temperature-sensitive hydrogels, based on 2-hydroxyethyl methacrylate (HEMA) and itaconic acid (IA) copolymers, were prepared by gamma-irradiation and characterized in order to examine their potential use in biomedical applications. The influence of comonomer ratio in these smart copolymers on their morphology, mechanical and thermal properties, biocompatibility and microbe penetration capability was investigated. The mechanical properties of copolymers were investigated using the dynamic mechanical analysis (DMA), while their thermal properties and morphology were examined by thermogravimetric analysis (TGA) and scanning electron microscopy (SEM). The morphology, mechanical and thermal properties of these hydrogels were found to be suitable for most requirements of biomedical applications. The in vitro study of P(HEMA/IA) biocompatibility showed no evidence of cell toxicity nor any considerable hemolytic activity. Furthermore, the microbe penetration test showed that neither Staphylococcus aureus nor Escherichia coli passed through the hydogel dressing; thus the P(HEMA/IA) dressing could be considered a good barrier against microbes. All results indicate that stimuli-responsive P(HEMA/IA) hydrogels have great potential for biomedical applications, especially for skin treatment and wound dressings.
PB  - Pergamon-Elsevier Science Ltd, Oxford
T2  - Radiation Physics and Chemistry
T1  - Smart poly(2-hydroxyethyl methacrylate/itaconic acid) hydrogels for biomedical application
EP  - 649
IS  - 5
SP  - 643
VL  - 79
DO  - 10.1016/j.radphyschem.2009.11.015
ER  - 

@article{
author = "Tomić, Simonida and Mićić, Maja M. and Dobić, Sava N. and Filipović, Jovanka M. and Suljovrujić, Edin H.",
year = "2010",
abstract = "pH- and temperature-sensitive hydrogels, based on 2-hydroxyethyl methacrylate (HEMA) and itaconic acid (IA) copolymers, were prepared by gamma-irradiation and characterized in order to examine their potential use in biomedical applications. The influence of comonomer ratio in these smart copolymers on their morphology, mechanical and thermal properties, biocompatibility and microbe penetration capability was investigated. The mechanical properties of copolymers were investigated using the dynamic mechanical analysis (DMA), while their thermal properties and morphology were examined by thermogravimetric analysis (TGA) and scanning electron microscopy (SEM). The morphology, mechanical and thermal properties of these hydrogels were found to be suitable for most requirements of biomedical applications. The in vitro study of P(HEMA/IA) biocompatibility showed no evidence of cell toxicity nor any considerable hemolytic activity. Furthermore, the microbe penetration test showed that neither Staphylococcus aureus nor Escherichia coli passed through the hydogel dressing; thus the P(HEMA/IA) dressing could be considered a good barrier against microbes. All results indicate that stimuli-responsive P(HEMA/IA) hydrogels have great potential for biomedical applications, especially for skin treatment and wound dressings.",
publisher = "Pergamon-Elsevier Science Ltd, Oxford",
journal = "Radiation Physics and Chemistry",
title = "Smart poly(2-hydroxyethyl methacrylate/itaconic acid) hydrogels for biomedical application",
pages = "649-643",
number = "5",
volume = "79",
doi = "10.1016/j.radphyschem.2009.11.015"
}

Tomić, S., Mićić, M. M., Dobić, S. N., Filipović, J. M.,& Suljovrujić, E. H.. (2010). Smart poly(2-hydroxyethyl methacrylate/itaconic acid) hydrogels for biomedical application. in Radiation Physics and Chemistry
Pergamon-Elsevier Science Ltd, Oxford., 79(5), 643-649.
https://doi.org/10.1016/j.radphyschem.2009.11.015

Tomić S, Mićić MM, Dobić SN, Filipović JM, Suljovrujić EH. Smart poly(2-hydroxyethyl methacrylate/itaconic acid) hydrogels for biomedical application. in Radiation Physics and Chemistry. 2010;79(5):643-649.
doi:10.1016/j.radphyschem.2009.11.015 .

Tomić, Simonida, Mićić, Maja M., Dobić, Sava N., Filipović, Jovanka M., Suljovrujić, Edin H., "Smart poly(2-hydroxyethyl methacrylate/itaconic acid) hydrogels for biomedical application" in Radiation Physics and Chemistry, 79, no. 5 (2010):643-649,
https://doi.org/10.1016/j.radphyschem.2009.11.015 . .

TY  - JOUR
AU  - Tomić, Simonida
AU  - Mićić, Maja M.
AU  - Filipović, Jovanka M.
AU  - Suljovrujić, Edin H.
PY  - 2010
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/1620
AB  - In this work, novel hydrogels based on 2-hydroxyethyl methacrylate (HEMA) and different poly(alkylene glycol)(meth)acrylates (BIS) were prepared by radiation-induced copolymerization. The influence of different BIS types with variation in chain length, based on ethylene glycol (EG) and/or propylene glycol (PG) pendant units, on the nature and inherent properties of P(HEMA/BIS) copolymeric hydrogels was the main idea of this paper. Swelling studies were conducted for all types of P(HEMA/BIS) copolymeric hydrogels in a wide pH and temperature range. Additional characterization of structure, morphology and thermal behaviour of the obtained hydrogels was conducted by Fourier transform infrared (FTIR) spectroscopy, scanning electron microscopy (SEM), and thermogravimetric (TG) analysis. The modelling of drug release and diffusion characteristics was tested using cephalexin (CEX). The results indicate that P(HEMA/BIS) hydrogels' properties are significantly dependent on the type of BIS. The hydrogels with ethylene glycol (EG) pendant chains show a noticeable pH and/or temperature sensitivity and can be considered smart hydrogels. The introduction of propylene glycol (PG) units, pure and mixed with ethylene glycol (EG) pendant chains, can additionally tune the characteristics of such gels. Furthermore, drug release studies indicate that these types of P(HEMA/BIS) copolymeric hydrogels are suitable candidates for controlled drug release systems.
PB  - Elsevier Science Sa, Lausanne
T2  - Chemical Engineering Journal
T1  - Synthesis, characterization and controlled release of cephalexin drug from smart poly(2-hydroxyethyl methacrylate/poly(alkylene glycol)(meth)acrylates hydrogels
EP  - 809
IS  - 2
SP  - 801
VL  - 160
DO  - 10.1016/j.cej.2010.03.089
ER  - 

@article{
author = "Tomić, Simonida and Mićić, Maja M. and Filipović, Jovanka M. and Suljovrujić, Edin H.",
year = "2010",
abstract = "In this work, novel hydrogels based on 2-hydroxyethyl methacrylate (HEMA) and different poly(alkylene glycol)(meth)acrylates (BIS) were prepared by radiation-induced copolymerization. The influence of different BIS types with variation in chain length, based on ethylene glycol (EG) and/or propylene glycol (PG) pendant units, on the nature and inherent properties of P(HEMA/BIS) copolymeric hydrogels was the main idea of this paper. Swelling studies were conducted for all types of P(HEMA/BIS) copolymeric hydrogels in a wide pH and temperature range. Additional characterization of structure, morphology and thermal behaviour of the obtained hydrogels was conducted by Fourier transform infrared (FTIR) spectroscopy, scanning electron microscopy (SEM), and thermogravimetric (TG) analysis. The modelling of drug release and diffusion characteristics was tested using cephalexin (CEX). The results indicate that P(HEMA/BIS) hydrogels' properties are significantly dependent on the type of BIS. The hydrogels with ethylene glycol (EG) pendant chains show a noticeable pH and/or temperature sensitivity and can be considered smart hydrogels. The introduction of propylene glycol (PG) units, pure and mixed with ethylene glycol (EG) pendant chains, can additionally tune the characteristics of such gels. Furthermore, drug release studies indicate that these types of P(HEMA/BIS) copolymeric hydrogels are suitable candidates for controlled drug release systems.",
publisher = "Elsevier Science Sa, Lausanne",
journal = "Chemical Engineering Journal",
title = "Synthesis, characterization and controlled release of cephalexin drug from smart poly(2-hydroxyethyl methacrylate/poly(alkylene glycol)(meth)acrylates hydrogels",
pages = "809-801",
number = "2",
volume = "160",
doi = "10.1016/j.cej.2010.03.089"
}

Tomić, S., Mićić, M. M., Filipović, J. M.,& Suljovrujić, E. H.. (2010). Synthesis, characterization and controlled release of cephalexin drug from smart poly(2-hydroxyethyl methacrylate/poly(alkylene glycol)(meth)acrylates hydrogels. in Chemical Engineering Journal
Elsevier Science Sa, Lausanne., 160(2), 801-809.
https://doi.org/10.1016/j.cej.2010.03.089

Tomić S, Mićić MM, Filipović JM, Suljovrujić EH. Synthesis, characterization and controlled release of cephalexin drug from smart poly(2-hydroxyethyl methacrylate/poly(alkylene glycol)(meth)acrylates hydrogels. in Chemical Engineering Journal. 2010;160(2):801-809.
doi:10.1016/j.cej.2010.03.089 .

Tomić, Simonida, Mićić, Maja M., Filipović, Jovanka M., Suljovrujić, Edin H., "Synthesis, characterization and controlled release of cephalexin drug from smart poly(2-hydroxyethyl methacrylate/poly(alkylene glycol)(meth)acrylates hydrogels" in Chemical Engineering Journal, 160, no. 2 (2010):801-809,
https://doi.org/10.1016/j.cej.2010.03.089 . .

TY  - JOUR
AU  - Tomić, Simonida
AU  - Mićić, Maja M.
AU  - Krezović, Bojana D.
AU  - Dobić, Sava N.
AU  - Suljovrujić, Edin H.
AU  - Filipović, Jovanka M.
PY  - 2009
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/1400
AB  - pH and temperature sensitive hydrogels, based on 2-hydroxyethyl methacrylate (HEMA) and itaconic acid (IA) copolymers, were prepared by gamma irradiation and characterized in order to examine their potential use in biomedical applications. The influence of comonomer ratio in these smart copolymers on their morphology, mechanical properties, biocompatibility and microbe penetration capability was investigated. The mechanical properties of copolymers were investigated using the dynamic mechanical analysis (DMA), while their morphology was examined by scanning electron microscopy (SEM). The morphology and mechanical properties of these hydrogels were found to be suitable for most requirements of biomedical applications. The in vitro study of P(HEMA/IA) biocompatibility showed no evidence of cell toxicity nor any considerable hemolytic activity. Furthermore, the microbe penetration test showed that neither Staphylococcus aureus nor Escherichia coli passed through the hydogel dressing; thus the P(HEMA/IA) dressing could be considered a good barrier against microbes. All results indicate that stimuli-responsive P(HEMA/IA) hydrogels have great potential for biomedical applications, especially for skin treatment and wound dressings.
AB  - pH i temperaturno osetljivi hidrogelovi na bazi kopolimera 2-hidroksietilmetakrilata (HEMA) i itakonske kiseline (IK) sintetisani su upotrebom gama zračenja i karakterisani s ciljem ispitivanja njihove potencijalne primene kao biomaterijala. Ispitivan je uticaj odnosa komonomera u ovim inteligentnim polimernim biomaterijalima na morfologiju, mehanička svojstva, biokompatibilnost i penetraciju mikroba. Mehanička svojstva kopolimera su ispitivana dinamičko-mehaničkom analizom (DMA), dok je morfologija karakterisana skenirajućom elektronskom mikroskopijom (SEM). Pokazalo se da su morfologija i mehanička svojstva ovih hidrogelova odgovarajući za većinu biomedicinskih primena. In vitro analizom biokompatibilnosti P(HEMA/IK) hidrogelova potvrđeno je da nisu toksični za ćelije niti izazivaju značajnu hemolitičku aktivnost. Takođe, test mikrobne penetracije pokazao je da ni Staphylococcus aureus ni Escherichia coli ne prolaze kroz hidrogelne obloge; stoga se P(HEMA/IK) obloge mogu smatrati dobrom barijerom protiv mikroba, a radi održavanja sterilnosti okolne sredine. Svi rezultati pokazuju da P(HEMA/IK) hidrogelovi imaju veliku mogućnost primene u biomedicini, posebno kod tretmana kože i kao obloge za opekotine.
PB  - Association of Chemical Engineers of Serbia
T2  - Hemijska industrija
T1  - Smart hydrogels based on itaconic acid for biomedical application
T1  - Inteligentni hidrogelovi na bazi itakonske kiseline za biomedicinsku primenu
EP  - 610
IS  - 6
SP  - 603
VL  - 63
DO  - 10.2298/HEMIND0906603T
ER  - 

@article{
author = "Tomić, Simonida and Mićić, Maja M. and Krezović, Bojana D. and Dobić, Sava N. and Suljovrujić, Edin H. and Filipović, Jovanka M.",
year = "2009",
abstract = "pH and temperature sensitive hydrogels, based on 2-hydroxyethyl methacrylate (HEMA) and itaconic acid (IA) copolymers, were prepared by gamma irradiation and characterized in order to examine their potential use in biomedical applications. The influence of comonomer ratio in these smart copolymers on their morphology, mechanical properties, biocompatibility and microbe penetration capability was investigated. The mechanical properties of copolymers were investigated using the dynamic mechanical analysis (DMA), while their morphology was examined by scanning electron microscopy (SEM). The morphology and mechanical properties of these hydrogels were found to be suitable for most requirements of biomedical applications. The in vitro study of P(HEMA/IA) biocompatibility showed no evidence of cell toxicity nor any considerable hemolytic activity. Furthermore, the microbe penetration test showed that neither Staphylococcus aureus nor Escherichia coli passed through the hydogel dressing; thus the P(HEMA/IA) dressing could be considered a good barrier against microbes. All results indicate that stimuli-responsive P(HEMA/IA) hydrogels have great potential for biomedical applications, especially for skin treatment and wound dressings., pH i temperaturno osetljivi hidrogelovi na bazi kopolimera 2-hidroksietilmetakrilata (HEMA) i itakonske kiseline (IK) sintetisani su upotrebom gama zračenja i karakterisani s ciljem ispitivanja njihove potencijalne primene kao biomaterijala. Ispitivan je uticaj odnosa komonomera u ovim inteligentnim polimernim biomaterijalima na morfologiju, mehanička svojstva, biokompatibilnost i penetraciju mikroba. Mehanička svojstva kopolimera su ispitivana dinamičko-mehaničkom analizom (DMA), dok je morfologija karakterisana skenirajućom elektronskom mikroskopijom (SEM). Pokazalo se da su morfologija i mehanička svojstva ovih hidrogelova odgovarajući za većinu biomedicinskih primena. In vitro analizom biokompatibilnosti P(HEMA/IK) hidrogelova potvrđeno je da nisu toksični za ćelije niti izazivaju značajnu hemolitičku aktivnost. Takođe, test mikrobne penetracije pokazao je da ni Staphylococcus aureus ni Escherichia coli ne prolaze kroz hidrogelne obloge; stoga se P(HEMA/IK) obloge mogu smatrati dobrom barijerom protiv mikroba, a radi održavanja sterilnosti okolne sredine. Svi rezultati pokazuju da P(HEMA/IK) hidrogelovi imaju veliku mogućnost primene u biomedicini, posebno kod tretmana kože i kao obloge za opekotine.",
publisher = "Association of Chemical Engineers of Serbia",
journal = "Hemijska industrija",
title = "Smart hydrogels based on itaconic acid for biomedical application, Inteligentni hidrogelovi na bazi itakonske kiseline za biomedicinsku primenu",
pages = "610-603",
number = "6",
volume = "63",
doi = "10.2298/HEMIND0906603T"
}

Tomić, S., Mićić, M. M., Krezović, B. D., Dobić, S. N., Suljovrujić, E. H.,& Filipović, J. M.. (2009). Smart hydrogels based on itaconic acid for biomedical application. in Hemijska industrija
Association of Chemical Engineers of Serbia., 63(6), 603-610.
https://doi.org/10.2298/HEMIND0906603T

Tomić S, Mićić MM, Krezović BD, Dobić SN, Suljovrujić EH, Filipović JM. Smart hydrogels based on itaconic acid for biomedical application. in Hemijska industrija. 2009;63(6):603-610.
doi:10.2298/HEMIND0906603T .

Tomić, Simonida, Mićić, Maja M., Krezović, Bojana D., Dobić, Sava N., Suljovrujić, Edin H., Filipović, Jovanka M., "Smart hydrogels based on itaconic acid for biomedical application" in Hemijska industrija, 63, no. 6 (2009):603-610,
https://doi.org/10.2298/HEMIND0906603T . .

TY  - JOUR
AU  - Tomić, Simonida
AU  - Mićić, Maja M.
AU  - Dokić, D.
AU  - Vasiljević-Radović, Dana
AU  - Filipović, Jovanka M.
AU  - Suljovrujić, Edin H.
PY  - 2009
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/1527
AB  - Silver(I) complexes based on itaconic acid hydrogel were prepared and characterized in order to examine the potential use of these materials. FTIR, AFM, in vitro fluid-uptake, metal sorption, and antibacterial activity assay measurements were used for the characterization. Silver(I) ion uptake by hydrogels based on 2-hydroxyethyl methacrylate (HEMA), ethylene glycol dimethacrylate (EGDMA), and different content of itaconic acid (2; 3.5; 5mol%) were determined by inductively coupled plasma mass spectrometry. The coordination sites for metal ions were identified, and the stability in in-vitro condition was determined. Incorporation of silver(I) ions into hydrogels and the influence of these ions on material diffusion properties were analyzed. It was found that the itaconic acid moiety is the determining factor which influences metal ion binding and, therefore, fluid uptake inside the polymer network. Furthermore, obtained hydrogels showed a satisfactory antibacterial activity.
PB  - Taylor & Francis Inc, Philadelphia
T2  - Materials and Manufacturing Processes
T1  - Preparation of Silver(I) Complexes with Itaconic Acid-Based Hydrogels for Biomedical Application
EP  - 1201
IS  - 10-11
SP  - 1197
VL  - 24
DO  - 10.1080/10426910903022247
ER  - 

@article{
author = "Tomić, Simonida and Mićić, Maja M. and Dokić, D. and Vasiljević-Radović, Dana and Filipović, Jovanka M. and Suljovrujić, Edin H.",
year = "2009",
abstract = "Silver(I) complexes based on itaconic acid hydrogel were prepared and characterized in order to examine the potential use of these materials. FTIR, AFM, in vitro fluid-uptake, metal sorption, and antibacterial activity assay measurements were used for the characterization. Silver(I) ion uptake by hydrogels based on 2-hydroxyethyl methacrylate (HEMA), ethylene glycol dimethacrylate (EGDMA), and different content of itaconic acid (2; 3.5; 5mol%) were determined by inductively coupled plasma mass spectrometry. The coordination sites for metal ions were identified, and the stability in in-vitro condition was determined. Incorporation of silver(I) ions into hydrogels and the influence of these ions on material diffusion properties were analyzed. It was found that the itaconic acid moiety is the determining factor which influences metal ion binding and, therefore, fluid uptake inside the polymer network. Furthermore, obtained hydrogels showed a satisfactory antibacterial activity.",
publisher = "Taylor & Francis Inc, Philadelphia",
journal = "Materials and Manufacturing Processes",
title = "Preparation of Silver(I) Complexes with Itaconic Acid-Based Hydrogels for Biomedical Application",
pages = "1201-1197",
number = "10-11",
volume = "24",
doi = "10.1080/10426910903022247"
}

Tomić, S., Mićić, M. M., Dokić, D., Vasiljević-Radović, D., Filipović, J. M.,& Suljovrujić, E. H.. (2009). Preparation of Silver(I) Complexes with Itaconic Acid-Based Hydrogels for Biomedical Application. in Materials and Manufacturing Processes
Taylor & Francis Inc, Philadelphia., 24(10-11), 1197-1201.
https://doi.org/10.1080/10426910903022247

Tomić S, Mićić MM, Dokić D, Vasiljević-Radović D, Filipović JM, Suljovrujić EH. Preparation of Silver(I) Complexes with Itaconic Acid-Based Hydrogels for Biomedical Application. in Materials and Manufacturing Processes. 2009;24(10-11):1197-1201.
doi:10.1080/10426910903022247 .

Tomić, Simonida, Mićić, Maja M., Dokić, D., Vasiljević-Radović, Dana, Filipović, Jovanka M., Suljovrujić, Edin H., "Preparation of Silver(I) Complexes with Itaconic Acid-Based Hydrogels for Biomedical Application" in Materials and Manufacturing Processes, 24, no. 10-11 (2009):1197-1201,
https://doi.org/10.1080/10426910903022247 . .

TY  - JOUR
AU  - Đošić, Marija
AU  - Mišković-Stanković, Vesna
AU  - Milonjić, Slobodan K.
AU  - Kačarević-Popović, Zorica M.
AU  - Bibić, Nataša M.
AU  - Stojanović, Jovica
PY  - 2008
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/1237
AB  - Electrochemical synthesis of hydroxyapatite powders was performed galvanostatically from homogeneous solution of Na(2)H(2)EDTA center dot 2H(2)O, NaH2PO4 and CaCl2 at a concentration relationship Ca/EDTA/PO43- of 0.25/0.25/0.15 M at current densities of 137 and 207 mA cm(-2) and pH values of 9.0 and 12.0. The hydroxyapatite powders were characterized by X-ray diffraction, size distribution measurements, transmission electron microscopy, scanning electron microscopy and thermogravimetric and differential thermal analysis. The influence of the electrochemical synthesis parameters, e.g. applied current density and pH value, on the phase composition, crystallite size, morphology and thermal characteristics of hydroxyapatite powders were investigated.
PB  - Elsevier Science Sa, Lausanne
T2  - Materials Chemistry and Physics
T1  - Electrochemical synthesis and characterization of hydroxyapatite powders
EP  - 142
IS  - 1
SP  - 137
VL  - 111
DO  - 10.1016/j.matchemphys.2008.03.045
ER  - 

@article{
author = "Đošić, Marija and Mišković-Stanković, Vesna and Milonjić, Slobodan K. and Kačarević-Popović, Zorica M. and Bibić, Nataša M. and Stojanović, Jovica",
year = "2008",
abstract = "Electrochemical synthesis of hydroxyapatite powders was performed galvanostatically from homogeneous solution of Na(2)H(2)EDTA center dot 2H(2)O, NaH2PO4 and CaCl2 at a concentration relationship Ca/EDTA/PO43- of 0.25/0.25/0.15 M at current densities of 137 and 207 mA cm(-2) and pH values of 9.0 and 12.0. The hydroxyapatite powders were characterized by X-ray diffraction, size distribution measurements, transmission electron microscopy, scanning electron microscopy and thermogravimetric and differential thermal analysis. The influence of the electrochemical synthesis parameters, e.g. applied current density and pH value, on the phase composition, crystallite size, morphology and thermal characteristics of hydroxyapatite powders were investigated.",
publisher = "Elsevier Science Sa, Lausanne",
journal = "Materials Chemistry and Physics",
title = "Electrochemical synthesis and characterization of hydroxyapatite powders",
pages = "142-137",
number = "1",
volume = "111",
doi = "10.1016/j.matchemphys.2008.03.045"
}

Đošić, M., Mišković-Stanković, V., Milonjić, S. K., Kačarević-Popović, Z. M., Bibić, N. M.,& Stojanović, J.. (2008). Electrochemical synthesis and characterization of hydroxyapatite powders. in Materials Chemistry and Physics
Elsevier Science Sa, Lausanne., 111(1), 137-142.
https://doi.org/10.1016/j.matchemphys.2008.03.045

Đošić M, Mišković-Stanković V, Milonjić SK, Kačarević-Popović ZM, Bibić NM, Stojanović J. Electrochemical synthesis and characterization of hydroxyapatite powders. in Materials Chemistry and Physics. 2008;111(1):137-142.
doi:10.1016/j.matchemphys.2008.03.045 .

Đošić, Marija, Mišković-Stanković, Vesna, Milonjić, Slobodan K., Kačarević-Popović, Zorica M., Bibić, Nataša M., Stojanović, Jovica, "Electrochemical synthesis and characterization of hydroxyapatite powders" in Materials Chemistry and Physics, 111, no. 1 (2008):137-142,
https://doi.org/10.1016/j.matchemphys.2008.03.045 . .

TY  - JOUR
AU  - Tomić, Simonida
AU  - Mićić, Maja M.
AU  - Filipović, Jovanka M.
AU  - Suljovrujić, Edin H.
PY  - 2007
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/1156
AB  - The copolymeric hydrogels based on 2-hydroxyethyl methacrylate (HEMA) and itaconic acid (IA) were synthesized by gamma radiation induced radical polymerization. Swelling and thermodynamic properties of PHEMA and copolymeric P(HEMA/IA) hydrogels with different IA contents (2, 3.5 and 5 mol%) were studied in a wide pH and temperature range. Initial studies of so-prepared hydrogels show interesting pH and temperature sensitivity in swelling and drug release behavior. Special attention was devoted to temperature investigations around physiological temperature (37 degrees C), where small changes in temperature significantly influence swelling and drug release of these hydrogels. Due to maximum swelling of hydrogels around 40 degrees C, the P(HEMA/IA) hydrogel containing 5mol% of IA without and with drug-antibiotic (gentamicin) were investigated at pH 7.40 and in the temperature range 25-42 degrees C, in order to evaluate their potential for medical applications.
PB  - Pergamon-Elsevier Science Ltd, Oxford
T2  - Radiation Physics and Chemistry
T1  - Swelling and thermodynamic studies of temperature responsive 2-hydroxyethyl methacrylate/itaconic acid copolymeric hydrogels prepared via gamma radiation
EP  - 1394
IS  - 8-9
SP  - 1390
VL  - 76
DO  - 10.1016/j.radphyschem.2007.02.038
ER  - 

@article{
author = "Tomić, Simonida and Mićić, Maja M. and Filipović, Jovanka M. and Suljovrujić, Edin H.",
year = "2007",
abstract = "The copolymeric hydrogels based on 2-hydroxyethyl methacrylate (HEMA) and itaconic acid (IA) were synthesized by gamma radiation induced radical polymerization. Swelling and thermodynamic properties of PHEMA and copolymeric P(HEMA/IA) hydrogels with different IA contents (2, 3.5 and 5 mol%) were studied in a wide pH and temperature range. Initial studies of so-prepared hydrogels show interesting pH and temperature sensitivity in swelling and drug release behavior. Special attention was devoted to temperature investigations around physiological temperature (37 degrees C), where small changes in temperature significantly influence swelling and drug release of these hydrogels. Due to maximum swelling of hydrogels around 40 degrees C, the P(HEMA/IA) hydrogel containing 5mol% of IA without and with drug-antibiotic (gentamicin) were investigated at pH 7.40 and in the temperature range 25-42 degrees C, in order to evaluate their potential for medical applications.",
publisher = "Pergamon-Elsevier Science Ltd, Oxford",
journal = "Radiation Physics and Chemistry",
title = "Swelling and thermodynamic studies of temperature responsive 2-hydroxyethyl methacrylate/itaconic acid copolymeric hydrogels prepared via gamma radiation",
pages = "1394-1390",
number = "8-9",
volume = "76",
doi = "10.1016/j.radphyschem.2007.02.038"
}

Tomić, S., Mićić, M. M., Filipović, J. M.,& Suljovrujić, E. H.. (2007). Swelling and thermodynamic studies of temperature responsive 2-hydroxyethyl methacrylate/itaconic acid copolymeric hydrogels prepared via gamma radiation. in Radiation Physics and Chemistry
Pergamon-Elsevier Science Ltd, Oxford., 76(8-9), 1390-1394.
https://doi.org/10.1016/j.radphyschem.2007.02.038

Tomić S, Mićić MM, Filipović JM, Suljovrujić EH. Swelling and thermodynamic studies of temperature responsive 2-hydroxyethyl methacrylate/itaconic acid copolymeric hydrogels prepared via gamma radiation. in Radiation Physics and Chemistry. 2007;76(8-9):1390-1394.
doi:10.1016/j.radphyschem.2007.02.038 .

Tomić, Simonida, Mićić, Maja M., Filipović, Jovanka M., Suljovrujić, Edin H., "Swelling and thermodynamic studies of temperature responsive 2-hydroxyethyl methacrylate/itaconic acid copolymeric hydrogels prepared via gamma radiation" in Radiation Physics and Chemistry, 76, no. 8-9 (2007):1390-1394,
https://doi.org/10.1016/j.radphyschem.2007.02.038 . .

TY  - JOUR
AU  - Mićić, Maja M.
AU  - Tomić, Simonida
AU  - Filipović, Jovanka M.
AU  - Suljovrujić, Edin H.
PY  - 2007
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/1019
AB  - Controlled release studies of drugs (theophylline (TH), fenethylline hydrochloride (FE) and gentamicin sulphate (GS)) from pH sensitive poly(2-hydroxyethyl methacrylate/itaconic acid) (P(HEMA/IA)) hydrogels obtained by gamma irradiation were carried out to investigate transport phenomena. Drug behavior and release profiles were analyzed using the restriction coefficient combining the influence of network structure and the size of the drug on release and transport properties. The results demonstrated that the ratio of drug radius to polymer pore size and drugpolymer interactions were dominant factors in hindering the diffusion process. The diffusivity of a drug through the hydrogels decreases with the size of the drug molecules and with the decrease in gel pore size. The diffusion equations for used drugs explain drug transport in hydrogels.
PB  - 8th Conference of the Yugoslav Materials Research Society
T2  - Materials Science Forum
T1  - Release and diffusion studies of hydrogels based on itaconic acid
EP  - 446
SP  - 441
VL  - 555
DO  - 10.4028/0-87849-441-3.441
ER  - 

@article{
author = "Mićić, Maja M. and Tomić, Simonida and Filipović, Jovanka M. and Suljovrujić, Edin H.",
year = "2007",
abstract = "Controlled release studies of drugs (theophylline (TH), fenethylline hydrochloride (FE) and gentamicin sulphate (GS)) from pH sensitive poly(2-hydroxyethyl methacrylate/itaconic acid) (P(HEMA/IA)) hydrogels obtained by gamma irradiation were carried out to investigate transport phenomena. Drug behavior and release profiles were analyzed using the restriction coefficient combining the influence of network structure and the size of the drug on release and transport properties. The results demonstrated that the ratio of drug radius to polymer pore size and drugpolymer interactions were dominant factors in hindering the diffusion process. The diffusivity of a drug through the hydrogels decreases with the size of the drug molecules and with the decrease in gel pore size. The diffusion equations for used drugs explain drug transport in hydrogels.",
publisher = "8th Conference of the Yugoslav Materials Research Society",
journal = "Materials Science Forum",
title = "Release and diffusion studies of hydrogels based on itaconic acid",
pages = "446-441",
volume = "555",
doi = "10.4028/0-87849-441-3.441"
}

Mićić, M. M., Tomić, S., Filipović, J. M.,& Suljovrujić, E. H.. (2007). Release and diffusion studies of hydrogels based on itaconic acid. in Materials Science Forum
8th Conference of the Yugoslav Materials Research Society., 555, 441-446.
https://doi.org/10.4028/0-87849-441-3.441

Mićić MM, Tomić S, Filipović JM, Suljovrujić EH. Release and diffusion studies of hydrogels based on itaconic acid. in Materials Science Forum. 2007;555:441-446.
doi:10.4028/0-87849-441-3.441 .

Mićić, Maja M., Tomić, Simonida, Filipović, Jovanka M., Suljovrujić, Edin H., "Release and diffusion studies of hydrogels based on itaconic acid" in Materials Science Forum, 555 (2007):441-446,
https://doi.org/10.4028/0-87849-441-3.441 . .

TY  - JOUR
AU  - Tomić, Simonida
AU  - Mićić, Maja M.
AU  - Filipović, Jovanka M.
AU  - Suljovrujić, Edin H.
PY  - 2007
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/1085
AB  - The new copolymeric hydrogels based on 2-hydroxyethyl methacrylate (HEMA) and itaconic acid (IA) were prepared by gamma irradiation, in order to examine the potential use of these hydrogels in controlled drug release systems. The influence of IA content in the gel on the swelling characteristics and the releasing behavior of hydrogels, and the effect of different drugs, theophylline (TPH) and fenethylline hydrochloride (FE), on the releasing behavior of P(HEMA/IA) matrix were investigated in vitro. The diffusion exponents for swelling and drug release indicate that the mechanisms of buffer uptake and drug release are governed by Fickian diffusion. The swelling kinetics and, therefore, the release rate depends on the matrix swelling degree. The drug release was faster for copolymeric hydrogels with a higher content of itaconic acid. Furthermore, the drug release for TPH as model drug was faster due to a smaller molecular size and a weaker interaction of the TPH molecules with(in) the P(HEMA/IA) copolymeric networks.
PB  - Pergamon-Elsevier Science Ltd, Oxford
T2  - Radiation Physics and Chemistry
T1  - Swelling and drug release behavior of poly(2-hydroxyethyl methacrylate/itaconic acid) copolymeric hydrogels obtained by gamma irradiation
EP  - 810
IS  - 5
SP  - 801
VL  - 76
DO  - 10.1016/j.radphyschem.2006.05.013
ER  - 

@article{
author = "Tomić, Simonida and Mićić, Maja M. and Filipović, Jovanka M. and Suljovrujić, Edin H.",
year = "2007",
abstract = "The new copolymeric hydrogels based on 2-hydroxyethyl methacrylate (HEMA) and itaconic acid (IA) were prepared by gamma irradiation, in order to examine the potential use of these hydrogels in controlled drug release systems. The influence of IA content in the gel on the swelling characteristics and the releasing behavior of hydrogels, and the effect of different drugs, theophylline (TPH) and fenethylline hydrochloride (FE), on the releasing behavior of P(HEMA/IA) matrix were investigated in vitro. The diffusion exponents for swelling and drug release indicate that the mechanisms of buffer uptake and drug release are governed by Fickian diffusion. The swelling kinetics and, therefore, the release rate depends on the matrix swelling degree. The drug release was faster for copolymeric hydrogels with a higher content of itaconic acid. Furthermore, the drug release for TPH as model drug was faster due to a smaller molecular size and a weaker interaction of the TPH molecules with(in) the P(HEMA/IA) copolymeric networks.",
publisher = "Pergamon-Elsevier Science Ltd, Oxford",
journal = "Radiation Physics and Chemistry",
title = "Swelling and drug release behavior of poly(2-hydroxyethyl methacrylate/itaconic acid) copolymeric hydrogels obtained by gamma irradiation",
pages = "810-801",
number = "5",
volume = "76",
doi = "10.1016/j.radphyschem.2006.05.013"
}

Tomić, S., Mićić, M. M., Filipović, J. M.,& Suljovrujić, E. H.. (2007). Swelling and drug release behavior of poly(2-hydroxyethyl methacrylate/itaconic acid) copolymeric hydrogels obtained by gamma irradiation. in Radiation Physics and Chemistry
Pergamon-Elsevier Science Ltd, Oxford., 76(5), 801-810.
https://doi.org/10.1016/j.radphyschem.2006.05.013

Tomić S, Mićić MM, Filipović JM, Suljovrujić EH. Swelling and drug release behavior of poly(2-hydroxyethyl methacrylate/itaconic acid) copolymeric hydrogels obtained by gamma irradiation. in Radiation Physics and Chemistry. 2007;76(5):801-810.
doi:10.1016/j.radphyschem.2006.05.013 .

Tomić, Simonida, Mićić, Maja M., Filipović, Jovanka M., Suljovrujić, Edin H., "Swelling and drug release behavior of poly(2-hydroxyethyl methacrylate/itaconic acid) copolymeric hydrogels obtained by gamma irradiation" in Radiation Physics and Chemistry, 76, no. 5 (2007):801-810,
https://doi.org/10.1016/j.radphyschem.2006.05.013 . .

TY  - JOUR
AU  - Tomić, Simonida
AU  - Suljovrujić, Edin H.
AU  - Filipović, Jovanka M.
PY  - 2006
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/961
AB  - Novel poly(Bisomer/HEMA/IA) hydrogels were prepared by radical copolymerization of poly(alkylene glycol) (meth)acrylates, i.e. short chains Bisomers, 2-hydroxyethyl methacrylate (HEMA) and itaconic acid (IA) in a mixture of water/ethanol as solvent. These hydrogels were characterized in terms of swelling in conditions similar to the biological fluids (pH range 2.20-7.40 buffer solutions), compression-strain measurements, thermal properties and morphology. The influence of the type of Bisomer and of the itaconic acid on swelling and mechanical properties, as well as on morphology and thermal behavior of the resulting hydrogels, were investigated. The in vitro study of biocompatibility, carried out with the hydrogels containing different types of Bisomers, showed no evidence of cell toxicity nor any considerable hemolytic activity. All hydrogels showed satisfactory bioadhesive properties, so these materials have potential as drug carriers or biological glue and sealants.
PB  - Springer, New York
T2  - Polymer Bulletin
T1  - Biocompatible and bioadhesive hydrogels based on 2-hydroxyethyl methacrylate, monofunctional poly(alkylene glycol)s and itaconic acid
EP  - 702
IS  - 5
SP  - 691
VL  - 57
DO  - 10.1007/s00289-006-0606-3
ER  - 

@article{
author = "Tomić, Simonida and Suljovrujić, Edin H. and Filipović, Jovanka M.",
year = "2006",
abstract = "Novel poly(Bisomer/HEMA/IA) hydrogels were prepared by radical copolymerization of poly(alkylene glycol) (meth)acrylates, i.e. short chains Bisomers, 2-hydroxyethyl methacrylate (HEMA) and itaconic acid (IA) in a mixture of water/ethanol as solvent. These hydrogels were characterized in terms of swelling in conditions similar to the biological fluids (pH range 2.20-7.40 buffer solutions), compression-strain measurements, thermal properties and morphology. The influence of the type of Bisomer and of the itaconic acid on swelling and mechanical properties, as well as on morphology and thermal behavior of the resulting hydrogels, were investigated. The in vitro study of biocompatibility, carried out with the hydrogels containing different types of Bisomers, showed no evidence of cell toxicity nor any considerable hemolytic activity. All hydrogels showed satisfactory bioadhesive properties, so these materials have potential as drug carriers or biological glue and sealants.",
publisher = "Springer, New York",
journal = "Polymer Bulletin",
title = "Biocompatible and bioadhesive hydrogels based on 2-hydroxyethyl methacrylate, monofunctional poly(alkylene glycol)s and itaconic acid",
pages = "702-691",
number = "5",
volume = "57",
doi = "10.1007/s00289-006-0606-3"
}

Tomić, S., Suljovrujić, E. H.,& Filipović, J. M.. (2006). Biocompatible and bioadhesive hydrogels based on 2-hydroxyethyl methacrylate, monofunctional poly(alkylene glycol)s and itaconic acid. in Polymer Bulletin
Springer, New York., 57(5), 691-702.
https://doi.org/10.1007/s00289-006-0606-3

Tomić S, Suljovrujić EH, Filipović JM. Biocompatible and bioadhesive hydrogels based on 2-hydroxyethyl methacrylate, monofunctional poly(alkylene glycol)s and itaconic acid. in Polymer Bulletin. 2006;57(5):691-702.
doi:10.1007/s00289-006-0606-3 .

Tomić, Simonida, Suljovrujić, Edin H., Filipović, Jovanka M., "Biocompatible and bioadhesive hydrogels based on 2-hydroxyethyl methacrylate, monofunctional poly(alkylene glycol)s and itaconic acid" in Polymer Bulletin, 57, no. 5 (2006):691-702,
https://doi.org/10.1007/s00289-006-0606-3 . .