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Radiation synthesis, characterisation and antimicrobial application of novel copolymeric silver/poly(2-hydroxyethyl methacrylate/itaconic acid) nanocomposite hydrogels
dc.creator | Mićić, Maja M. | |
dc.creator | Milić-Vukašinović, Tanja | |
dc.creator | Mitrić, Miodrag | |
dc.creator | Jokić, Bojan M. | |
dc.creator | Suljovrujić, Edin H. | |
dc.date.accessioned | 2018-03-01T23:44:39Z | |
dc.date.accessioned | 2023-02-01T12:59:51Z | |
dc.date.available | 2018-03-01T23:44:39Z | |
dc.date.available | 2023-02-01T12:59:51Z | |
dc.date.issued | 2013 | |
dc.identifier.issn | 0170-0839 | |
dc.identifier.issn | 1436-2449 | |
dc.identifier.uri | http://TechnoRep.tmf.bg.ac.rs/handle/123456789/5713 | |
dc.description.abstract | Silver nanoparticles were fabricated via in situ reduction of silver nitrate embedded in swollen P(HEMA/IA) hydrogel, using gamma radiolysis method. Copolymeric hydrogels based on 2-hydroxyethyl methacrylate (HEMA) and itaconic acid (IA), previously synthesised by gamma radiation for wound dressing application, were used as a carrier and a stabilising agent, while ethyl alcohol was used as a free radical scavenger. The influence of different P(HEMA/IA) hydrogels and silver salt concentrations on the size and distribution of nanoparticles was investigated. The Ag/P(HEMA/IA) nanocomposites were characterised by high resolution scanning electron microscopy, energy dispersive spectroscopy, wide-angle X-ray diffraction, UV-Vis spectroscopy and swelling measurements. Escherichia coli (Gram-negative bacterium), Staphylococcus aureus (Gram-positive bacterium) and Candida albicans (fungus) were used to prove the antimicrobial properties of Ag/P(HEMA/IA) nanocomposites. The inhibition kinetics of bacteria growth was investigated by measuring the colony-forming unit. The antimicrobial effectiveness of the Ag/P(HEMA/IA) hydrogel nanocomposite was demonstrated even at small silver concentrations. P(HEMA/IA) hydrogels containing nanosilver particles was found suitable to be used as wound dressing. | en |
dc.relation | info:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172026/RS// | |
dc.rights | restrictedAccess | en |
dc.rights | restrictedAccess | |
dc.source | Polymer Bulletin | en |
dc.subject | Ag nanoparticles (AgNPs) | en |
dc.subject | Gamma radiation | en |
dc.subject | P(HEMA/IA) hydrogel | en |
dc.subject | Antimicrobial activity | en |
dc.title | Radiation synthesis, characterisation and antimicrobial application of novel copolymeric silver/poly(2-hydroxyethyl methacrylate/itaconic acid) nanocomposite hydrogels | en |
dc.type | article | en |
dc.rights.license | ARR | |
dc.citation.epage | 3357 | |
dc.citation.issue | 12 | |
dc.citation.rank | M23 | |
dc.citation.spage | 3347 | |
dc.citation.volume | 70 | |
dc.identifier.doi | 10.1007/s00289-013-1026-9 | |
dc.identifier.scopus | 2-s2.0-84886085710 | |
dc.identifier.wos | 000325774400008 | |
dc.type.version | publishedVersion |