TY  - JOUR
AU  - Nevešćanin, Marina
AU  - Avramov-Ivić, Milka
AU  - Petrović, Slobodan
AU  - Mijin, Dušan
AU  - Stević-Banović, Sonja N.
AU  - Jovanović, Vladislava M.
PY  - 2013
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/2358
AB  - The catalytic abilities of a gold electrode were tested for the quantitative determination of amphetamine (A) and 3,4-methylenedioxy-N-methylamphetamine (MDMA) standards by their oxidation using cyclic voltammetry (CV). The values of the oxidative currents of A and MDMA standards at 0.80 V vs. SCE in 0.05 M NaHCO3 at a scan rate of 50 mV s-1 were linear functions of the concentration in range of 110.9-258.9 μM and 38.7-229.2 μM, respectively. Square wave voltammetry (SWV) revealed a linear increase of current with the concentration of MDMA (range 30.9-91.6 μM), which enabled the quantitative determination of amphetamine derivates. SWV analysis was also successfully performed in spiked urine samples. A and MDMA in the presence of sucrose and as a content in illegally produced tablets were also determined. The voltammetric determinations of A and MDMA derivatives using CV and SWV at gold a electrode are rapid, selective and simple procedures and their accuracy was confirmed with a reference method, high performance liquid chromatography (HPLC). The analysis of spiked urine samples offers an additional possibility for the rapid detection of A and MDMA in human urine.
AB  - Katalitička svojstva elektrode od zlata su testirana za kvantitativno određivanje amfetamina (A) i 3,4-metilendioksi-N-metilamfetamina (MDMA) standarda. Elektroksidacija A i MDMA je praćena cikličnom voltametrijom (CV). Vrednost oksidativnog pika A i MDMA standarda je linearna funkcija koncentracija u opsegu 110,9-258,9 μM (A) i 38,7-229,2 μM (MDMA). Voltametrija sa pravougaonim impulsima (SWV) je pokazala linearnu zavisnost struja od koncentracija za MDMA standard (u opsegu: 30,9-91,6 μM) kao i u spajkovanim uzorcima humanog urina. Uspešno je analiziran i sadržaj A i MDMA u ilegalno proizvedenim tabletama. Voltametrijsko određivanje A i MDMA derivata uz pomoć CV i SWV na elektrodi od zlata je brza, selektivna i jednostavna procedura. Analiza spajkovanih uzoraka urina nudi dodatnu mogućnost za brzu detekciju A i MDMA u humanom urinu.
PB  - Serbian Chemical Society, Belgrade
T2  - Journal of the Serbian Chemical Society
T1  - The use of a gold electrode for the determination of amphetamine derivatives and application to their analysis in human urine
T1  - Određivanje derivata amfetamina i primena u analizi humanog urina na elektrodi od zlata
EP  - 1385
IS  - 9
SP  - 1373
VL  - 78
UR  - https://hdl.handle.net/21.15107/rcub_technorep_2358
ER  - 

@article{
author = "Nevešćanin, Marina and Avramov-Ivić, Milka and Petrović, Slobodan and Mijin, Dušan and Stević-Banović, Sonja N. and Jovanović, Vladislava M.",
year = "2013",
abstract = "The catalytic abilities of a gold electrode were tested for the quantitative determination of amphetamine (A) and 3,4-methylenedioxy-N-methylamphetamine (MDMA) standards by their oxidation using cyclic voltammetry (CV). The values of the oxidative currents of A and MDMA standards at 0.80 V vs. SCE in 0.05 M NaHCO3 at a scan rate of 50 mV s-1 were linear functions of the concentration in range of 110.9-258.9 μM and 38.7-229.2 μM, respectively. Square wave voltammetry (SWV) revealed a linear increase of current with the concentration of MDMA (range 30.9-91.6 μM), which enabled the quantitative determination of amphetamine derivates. SWV analysis was also successfully performed in spiked urine samples. A and MDMA in the presence of sucrose and as a content in illegally produced tablets were also determined. The voltammetric determinations of A and MDMA derivatives using CV and SWV at gold a electrode are rapid, selective and simple procedures and their accuracy was confirmed with a reference method, high performance liquid chromatography (HPLC). The analysis of spiked urine samples offers an additional possibility for the rapid detection of A and MDMA in human urine., Katalitička svojstva elektrode od zlata su testirana za kvantitativno određivanje amfetamina (A) i 3,4-metilendioksi-N-metilamfetamina (MDMA) standarda. Elektroksidacija A i MDMA je praćena cikličnom voltametrijom (CV). Vrednost oksidativnog pika A i MDMA standarda je linearna funkcija koncentracija u opsegu 110,9-258,9 μM (A) i 38,7-229,2 μM (MDMA). Voltametrija sa pravougaonim impulsima (SWV) je pokazala linearnu zavisnost struja od koncentracija za MDMA standard (u opsegu: 30,9-91,6 μM) kao i u spajkovanim uzorcima humanog urina. Uspešno je analiziran i sadržaj A i MDMA u ilegalno proizvedenim tabletama. Voltametrijsko određivanje A i MDMA derivata uz pomoć CV i SWV na elektrodi od zlata je brza, selektivna i jednostavna procedura. Analiza spajkovanih uzoraka urina nudi dodatnu mogućnost za brzu detekciju A i MDMA u humanom urinu.",
publisher = "Serbian Chemical Society, Belgrade",
journal = "Journal of the Serbian Chemical Society",
title = "The use of a gold electrode for the determination of amphetamine derivatives and application to their analysis in human urine, Određivanje derivata amfetamina i primena u analizi humanog urina na elektrodi od zlata",
pages = "1385-1373",
number = "9",
volume = "78",
url = "https://hdl.handle.net/21.15107/rcub_technorep_2358"
}

Nevešćanin, M., Avramov-Ivić, M., Petrović, S., Mijin, D., Stević-Banović, S. N.,& Jovanović, V. M.. (2013). The use of a gold electrode for the determination of amphetamine derivatives and application to their analysis in human urine. in Journal of the Serbian Chemical Society
Serbian Chemical Society, Belgrade., 78(9), 1373-1385.
https://hdl.handle.net/21.15107/rcub_technorep_2358

Nevešćanin M, Avramov-Ivić M, Petrović S, Mijin D, Stević-Banović SN, Jovanović VM. The use of a gold electrode for the determination of amphetamine derivatives and application to their analysis in human urine. in Journal of the Serbian Chemical Society. 2013;78(9):1373-1385.
https://hdl.handle.net/21.15107/rcub_technorep_2358 .

Nevešćanin, Marina, Avramov-Ivić, Milka, Petrović, Slobodan, Mijin, Dušan, Stević-Banović, Sonja N., Jovanović, Vladislava M., "The use of a gold electrode for the determination of amphetamine derivatives and application to their analysis in human urine" in Journal of the Serbian Chemical Society, 78, no. 9 (2013):1373-1385,
https://hdl.handle.net/21.15107/rcub_technorep_2358 .

TY  - JOUR
AU  - Ilić, Nataša
AU  - Marinković, Aleksandar
AU  - Mijin, Dušan
AU  - Nevešćanin, Marina
AU  - Petrović, Slobodan
PY  - 2010
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/1662
AB  - The electron-ionization induced mass spectra of twenty six N-monosubstituted cyanoacetamides were recorded and their fragmentation patterns were studied. The effect of N-alkyl and N-aryl substituents to the fragmentation of the investigated compounds was discussed. Mechanistic generalization lead to a conclusion that fission of the carbon-carbon bonds next to carbonyl function or nitrogen were processes common for N-alkyl and N-(4-substituted phenyl) cyanoacetamides. In some amides, the elimination of the acyl group by a ketene fragment gave rise to the more stable ion. Cycloalkyl amides could not fragment by single carbon-carbon bond fission, but subsequent rearrangement resulted in formation of stable even electron ion. N-(4-substituted phenyl) cyanoacetamides were more stable showing also characteristic fragmentation depending on substituent present at phenyl ring.
AB  - U ovom radu su proučavani fragmentacioni putevi dvadeset šest N-monosupstituisanih cijanoacetamida dobijenih jonizacijom izazvanom bombardovanjem elektronima. Na osnovu definisanih fragmentacionih puteva diskutovan je uticaj prisutnih N-alkil i N-aril supstituenata. Sagledavanjem mehanizama fragmentacija ispitivanih N-monosupstituisanih cijanoacetamida uočava se da je cepanje veze ugljenik-ugljenik susedne karbonilnoj grupi ili azotu proces uočen i kod N-alkil i N-(4-supstituisanih fenil) cijanoacetamida. Kod nekih amida, eliminacija acil grupe u vidu fragmenta ketena dovodi do nastajanju stabilnijih jona. Cikloalkil amidi ne mogu da se fragmentišu samo cepanjem veze ugljenik-ugljenik, već u narednom koraku pregradnje daju stabilnije parne jone. N-(4-supstituisani fenil) cijanoacetamidi se stabilni u primenjenim jonizacionim uslovima i pokazuju karakteristične fragmentcije na koje utiče prisutni supstituent na fenilnom jezgru.
PB  - Association of the Chemical Engineers of Serbia
T2  - Chemical Industry & Chemical Engineering Quarterly
T1  - EI/MS/MS spectra of N-monosubstituted cyanoacetamides
T1  - EI/MS/MS spektri N-monosupstituisanih cijanoacetamida
EP  - 397
IS  - 4
SP  - 387
VL  - 16
DO  - 10.2298/CICEQ100421042I
ER  - 

@article{
author = "Ilić, Nataša and Marinković, Aleksandar and Mijin, Dušan and Nevešćanin, Marina and Petrović, Slobodan",
year = "2010",
abstract = "The electron-ionization induced mass spectra of twenty six N-monosubstituted cyanoacetamides were recorded and their fragmentation patterns were studied. The effect of N-alkyl and N-aryl substituents to the fragmentation of the investigated compounds was discussed. Mechanistic generalization lead to a conclusion that fission of the carbon-carbon bonds next to carbonyl function or nitrogen were processes common for N-alkyl and N-(4-substituted phenyl) cyanoacetamides. In some amides, the elimination of the acyl group by a ketene fragment gave rise to the more stable ion. Cycloalkyl amides could not fragment by single carbon-carbon bond fission, but subsequent rearrangement resulted in formation of stable even electron ion. N-(4-substituted phenyl) cyanoacetamides were more stable showing also characteristic fragmentation depending on substituent present at phenyl ring., U ovom radu su proučavani fragmentacioni putevi dvadeset šest N-monosupstituisanih cijanoacetamida dobijenih jonizacijom izazvanom bombardovanjem elektronima. Na osnovu definisanih fragmentacionih puteva diskutovan je uticaj prisutnih N-alkil i N-aril supstituenata. Sagledavanjem mehanizama fragmentacija ispitivanih N-monosupstituisanih cijanoacetamida uočava se da je cepanje veze ugljenik-ugljenik susedne karbonilnoj grupi ili azotu proces uočen i kod N-alkil i N-(4-supstituisanih fenil) cijanoacetamida. Kod nekih amida, eliminacija acil grupe u vidu fragmenta ketena dovodi do nastajanju stabilnijih jona. Cikloalkil amidi ne mogu da se fragmentišu samo cepanjem veze ugljenik-ugljenik, već u narednom koraku pregradnje daju stabilnije parne jone. N-(4-supstituisani fenil) cijanoacetamidi se stabilni u primenjenim jonizacionim uslovima i pokazuju karakteristične fragmentcije na koje utiče prisutni supstituent na fenilnom jezgru.",
publisher = "Association of the Chemical Engineers of Serbia",
journal = "Chemical Industry & Chemical Engineering Quarterly",
title = "EI/MS/MS spectra of N-monosubstituted cyanoacetamides, EI/MS/MS spektri N-monosupstituisanih cijanoacetamida",
pages = "397-387",
number = "4",
volume = "16",
doi = "10.2298/CICEQ100421042I"
}

Ilić, N., Marinković, A., Mijin, D., Nevešćanin, M.,& Petrović, S.. (2010). EI/MS/MS spectra of N-monosubstituted cyanoacetamides. in Chemical Industry & Chemical Engineering Quarterly
Association of the Chemical Engineers of Serbia., 16(4), 387-397.
https://doi.org/10.2298/CICEQ100421042I

Ilić N, Marinković A, Mijin D, Nevešćanin M, Petrović S. EI/MS/MS spectra of N-monosubstituted cyanoacetamides. in Chemical Industry & Chemical Engineering Quarterly. 2010;16(4):387-397.
doi:10.2298/CICEQ100421042I .

Ilić, Nataša, Marinković, Aleksandar, Mijin, Dušan, Nevešćanin, Marina, Petrović, Slobodan, "EI/MS/MS spectra of N-monosubstituted cyanoacetamides" in Chemical Industry & Chemical Engineering Quarterly, 16, no. 4 (2010):387-397,
https://doi.org/10.2298/CICEQ100421042I . .

TY  - JOUR
AU  - Nevešćanin, Marina
AU  - Banović-Stević, Sonja
AU  - Petrović, Slobodan
AU  - Vajs, Vlatka
PY  - 2008
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/1344
AB  - Forensic practice in the Republic of Serbia faced the illegal production of amphetamine for the first time in 2003. This paper presents the results of the chemical characterization of 32 batches of amphetamine samples from three separate cases, for the purpose of identification of the active components and additives. Through the profiling of impurities of all samples, using gas chromatography/mass spectrometry (GC/MS), 30 compounds associated with amphetamine were identified. The results of the analysis of powder tartrate, sulfate and phosphate salts of amphetamine, as well as variously formulated tablets are presented in this study. The analyses showed that the amphetamines were synthesized by the Leuckart method in all cases.
AB  - Forenzička praksa u Republici Srbiji se prvi put srela sa ilegalnom proizvodnjom amfetamina 2003. godine. U ovom radu predstavljeni su rezultati hemijske karakterizacije 32 vrste uzoraka amfetamina koji potiču iz tri odvojena slučaja u cilju identifikacije aktivnih komponenti i aditiva. Profilisanjem nečistoća svih uzoraka pomoću gasno-masene spektrometrije identifikovano je 30 jedinjenja povezanih sa amfetaminom. Dati su rezultati analiza praškastih tartaratnih, sulfatnih i fosfatnih soli amfetamina kao i različito formulisanih tableta. Analize nečistoća su pokazale da je u svim slučajevima sinteza amfetamina vršena Leuckart-ovom reakcijom.
PB  - Serbian Chemical Society, Belgrade
T2  - Journal of the Serbian Chemical Society
T1  - Analysis of amphetamines illegally produced in Serbia
T1  - Analiza amfetamina ilegalno proizvedenog u Srbiji
EP  - 701
IS  - 7
SP  - 691
VL  - 73
UR  - https://hdl.handle.net/21.15107/rcub_technorep_1344
ER  - 

@article{
author = "Nevešćanin, Marina and Banović-Stević, Sonja and Petrović, Slobodan and Vajs, Vlatka",
year = "2008",
abstract = "Forensic practice in the Republic of Serbia faced the illegal production of amphetamine for the first time in 2003. This paper presents the results of the chemical characterization of 32 batches of amphetamine samples from three separate cases, for the purpose of identification of the active components and additives. Through the profiling of impurities of all samples, using gas chromatography/mass spectrometry (GC/MS), 30 compounds associated with amphetamine were identified. The results of the analysis of powder tartrate, sulfate and phosphate salts of amphetamine, as well as variously formulated tablets are presented in this study. The analyses showed that the amphetamines were synthesized by the Leuckart method in all cases., Forenzička praksa u Republici Srbiji se prvi put srela sa ilegalnom proizvodnjom amfetamina 2003. godine. U ovom radu predstavljeni su rezultati hemijske karakterizacije 32 vrste uzoraka amfetamina koji potiču iz tri odvojena slučaja u cilju identifikacije aktivnih komponenti i aditiva. Profilisanjem nečistoća svih uzoraka pomoću gasno-masene spektrometrije identifikovano je 30 jedinjenja povezanih sa amfetaminom. Dati su rezultati analiza praškastih tartaratnih, sulfatnih i fosfatnih soli amfetamina kao i različito formulisanih tableta. Analize nečistoća su pokazale da je u svim slučajevima sinteza amfetamina vršena Leuckart-ovom reakcijom.",
publisher = "Serbian Chemical Society, Belgrade",
journal = "Journal of the Serbian Chemical Society",
title = "Analysis of amphetamines illegally produced in Serbia, Analiza amfetamina ilegalno proizvedenog u Srbiji",
pages = "701-691",
number = "7",
volume = "73",
url = "https://hdl.handle.net/21.15107/rcub_technorep_1344"
}

Nevešćanin, M., Banović-Stević, S., Petrović, S.,& Vajs, V.. (2008). Analysis of amphetamines illegally produced in Serbia. in Journal of the Serbian Chemical Society
Serbian Chemical Society, Belgrade., 73(7), 691-701.
https://hdl.handle.net/21.15107/rcub_technorep_1344

Nevešćanin M, Banović-Stević S, Petrović S, Vajs V. Analysis of amphetamines illegally produced in Serbia. in Journal of the Serbian Chemical Society. 2008;73(7):691-701.
https://hdl.handle.net/21.15107/rcub_technorep_1344 .

Nevešćanin, Marina, Banović-Stević, Sonja, Petrović, Slobodan, Vajs, Vlatka, "Analysis of amphetamines illegally produced in Serbia" in Journal of the Serbian Chemical Society, 73, no. 7 (2008):691-701,
https://hdl.handle.net/21.15107/rcub_technorep_1344 .

TY  - JOUR
AU  - Marinković, Aleksandar
AU  - Perić-Grujić, Aleksandra
AU  - Jovanović, Bratislav Ž.
AU  - Ilić, Nataša
AU  - Nevešćanin, Marina
PY  - 2006
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/960
PB  - John Wiley & Sons Ltd, Chichester
T2  - Rapid Communications in Mass Spectrometry
T1  - Electron ionization tandem mass spectra of some 3-cyano-4-substituted phenyl-6-phenyl-2(1H)-pyridones
EP  - 2633
IS  - 17
SP  - 2630
VL  - 20
DO  - 10.1002/rcm.2630
ER  - 

@article{
author = "Marinković, Aleksandar and Perić-Grujić, Aleksandra and Jovanović, Bratislav Ž. and Ilić, Nataša and Nevešćanin, Marina",
year = "2006",
publisher = "John Wiley & Sons Ltd, Chichester",
journal = "Rapid Communications in Mass Spectrometry",
title = "Electron ionization tandem mass spectra of some 3-cyano-4-substituted phenyl-6-phenyl-2(1H)-pyridones",
pages = "2633-2630",
number = "17",
volume = "20",
doi = "10.1002/rcm.2630"
}

Marinković, A., Perić-Grujić, A., Jovanović, B. Ž., Ilić, N.,& Nevešćanin, M.. (2006). Electron ionization tandem mass spectra of some 3-cyano-4-substituted phenyl-6-phenyl-2(1H)-pyridones. in Rapid Communications in Mass Spectrometry
John Wiley & Sons Ltd, Chichester., 20(17), 2630-2633.
https://doi.org/10.1002/rcm.2630

Marinković A, Perić-Grujić A, Jovanović BŽ, Ilić N, Nevešćanin M. Electron ionization tandem mass spectra of some 3-cyano-4-substituted phenyl-6-phenyl-2(1H)-pyridones. in Rapid Communications in Mass Spectrometry. 2006;20(17):2630-2633.
doi:10.1002/rcm.2630 .

Marinković, Aleksandar, Perić-Grujić, Aleksandra, Jovanović, Bratislav Ž., Ilić, Nataša, Nevešćanin, Marina, "Electron ionization tandem mass spectra of some 3-cyano-4-substituted phenyl-6-phenyl-2(1H)-pyridones" in Rapid Communications in Mass Spectrometry, 20, no. 17 (2006):2630-2633,
https://doi.org/10.1002/rcm.2630 . .