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dc.creatorPerišić-Janjić, Nada
dc.creatorVastag, Gyongyi
dc.creatorTomić, Jelena
dc.creatorPetrović, Slobodan
dc.date.accessioned2021-03-10T10:47:01Z
dc.date.available2021-03-10T10:47:01Z
dc.date.issued2007
dc.identifier.issn0933-4173
dc.identifier.urihttp://TechnoRep.tmf.bg.ac.rs/handle/123456789/1148
dc.description.abstractThe chromatographic behavior of some N,N-disubstituted-2-phenylacetamide derivatives has been studied on the chemically bonded stationary phase RP-C-18 with acetone, acetonitrile, tetrahydrofuran, dioxane, methanol, ethanol, 1-propanol, and 2-propanol as organic modifiers of aqueous mobile phases. The retention observed with different mobile-phase modifiers was correlated. The effects of different physicochemical properties of the compounds on retention behavior when chromatographed with aqueous mobile phases containing protic and aprotic modifiers were also studied. Multiple linear regression analysis was used to correlate chromatographic retention constants of the compounds with physicochemical properties. The chromatographic lipophilicity R-M(0) (determined by linear extrapolation) was correlated with log P values calculated by use of different theoretical methods. Good relationships were obtained for all the systems investigated. Good correlation was obtained between lipophilicity measured chromatographically and biological activity predictors.en
dc.publisherAkademiai Kiado Zrt, Budapest
dc.rightsrestrictedAccess
dc.sourceJPC-Journal of Planar Chromatography-Modern Tlc
dc.subjectRP-C18 TLCen
dc.subjectN,N-Disubstituted-2-phenylacetamidesen
dc.subjectlipophilicityen
dc.subjectcorrelation analysisen
dc.subjectbiological activityen
dc.titleEffect of the physicochemical properties of N,N-Disubstituted-2-phenylacetamide derivatives on their retention behavior in RP-TLCen
dc.typearticle
dc.rights.licenseARR
dc.citation.epage359
dc.citation.issue5
dc.citation.other20(5): 353-359
dc.citation.rankM23
dc.citation.spage353
dc.citation.volume20
dc.identifier.doi10.1556/JPC.20.2007.5.8
dc.identifier.rcubconv_2934
dc.identifier.scopus2-s2.0-35848935423
dc.identifier.wos000252110600008
dc.type.versionpublishedVersion


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