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dc.creatorPajić-Lijaković, Ivana
dc.creatorPlavšić, Milenko B.
dc.creatorNedović, Viktor
dc.creatorBugarski, Branko
dc.date.accessioned2021-03-10T10:47:43Z
dc.date.available2021-03-10T10:47:43Z
dc.date.issued2007
dc.identifier.issn0265-2048
dc.identifier.urihttp://TechnoRep.tmf.bg.ac.rs/handle/123456789/1159
dc.description.abstractThe rheological model is developed to elucidate the mechanism of Ca-alginate microbead deformation in the course of cell growth within. It is a complex process influenced by relaxation of the expanded polymer network inside a bead, and forces generated by cell growth inside the bead and interactions between solvent, network parts and cells as well. The resulting effects are measured experimentally by estimating isotropic volumetric deformations of beads with yeast cells as function of time and cell concentration per bead. The mathematical model of the process is developed based on a modified general Zener model with fractional derivatives. It is particularly suitable for incorporating effects of different nature also during different stages of such complex process development. The results of theoretical analyses using the model developed and comparison with experimental values obtained, indicate a high impact of partial decomposition, i.e. plastic response of polymer network inside a bead due to cell growth, on bead deformation. For comparison, corresponding deformation measurements and modelling were performed on the same network system exposed to swelling in the solvent, but without the cells. In this case elastic forces are dominant, indicating different mechanism of relaxation without the influence of cells, in agreement with previous conclusions.en
dc.publisherTaylor & Francis Ltd, Abingdon
dc.rightsrestrictedAccess
dc.sourceJournal of Microencapsulation
dc.subjectmicrobeaden
dc.subjectyeasten
dc.subjectalginatesen
dc.subjectcell growthen
dc.subjectgel deformation mechanismen
dc.titleInvestigation of Ca-alginate hydrogel rheological behaviour in conjunction with immobilized yeast cell growth dynamicsen
dc.typearticle
dc.rights.licenseARR
dc.citation.epage429
dc.citation.issue5
dc.citation.other24(5): 420-429
dc.citation.rankM22
dc.citation.spage420
dc.citation.volume24
dc.identifier.doi10.1080/02652040701362843
dc.identifier.pmid17578732
dc.identifier.rcubconv_2847
dc.identifier.scopus2-s2.0-34347217518
dc.identifier.wos000247967000003
dc.type.versionpublishedVersion


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