Size and surface effects on the MRI relaxivity of manganese ferrite nanoparticle contrast agents
Samo za registrovane korisnike
2007
Autori
Tromsdorf, Ulrich I.Bigall, Nadja C.
Kaul, Michael G.
Bruns, Oliver T.
Nikolić, Marija
Mollwitz, Birgit
Sperling, Ralph A.
Reimer, Rudolph
Hohenberg, Heinz
Parak, Wolfgang J.
Forster, Stephan
Beisiegel, Ulrike
Adam, Gerhard
Weller, Horst
Članak u časopisu (Objavljena verzija)
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
Superparamagnetic MnFe2O4 nanocrystals of different sizes were synthesized in high-boiling ether solvent and transferred into water using three different approaches. First, we applied a ligand exchange in order to form a water soluble polymer shell. Second, the particles were embedded into an amphiphilic polymer shell. Third, the nanoparticles were embedded into large micelles formed by lipids. Although all approaches lead to effective negative contrast enhancement, we observed significant differences concerning the magnitude of this effect. The transverse relaxivity, in particular r(2)*, is greatly higher for the micellar system compared to the polymer-coated particles using same-sized nanoparticles. We also observed an increase in transverse relaxivities with increasing particle size for the polymer-coated nanocrystals. The results are qualitatively compared with theoretical models describing the dependence of relaxivity on the size of magnetic spheres.
Izvor:
Nano Letters, 2007, 7, 8, 2422-2427Izdavač:
- Amer Chemical Soc, Washington
DOI: 10.1021/nl071099b
ISSN: 1530-6984
PubMed: 17658761
WoS: 000248657800045
Scopus: 2-s2.0-34548171034
Institucija/grupa
Tehnološko-metalurški fakultetTY - JOUR AU - Tromsdorf, Ulrich I. AU - Bigall, Nadja C. AU - Kaul, Michael G. AU - Bruns, Oliver T. AU - Nikolić, Marija AU - Mollwitz, Birgit AU - Sperling, Ralph A. AU - Reimer, Rudolph AU - Hohenberg, Heinz AU - Parak, Wolfgang J. AU - Forster, Stephan AU - Beisiegel, Ulrike AU - Adam, Gerhard AU - Weller, Horst PY - 2007 UR - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/1165 AB - Superparamagnetic MnFe2O4 nanocrystals of different sizes were synthesized in high-boiling ether solvent and transferred into water using three different approaches. First, we applied a ligand exchange in order to form a water soluble polymer shell. Second, the particles were embedded into an amphiphilic polymer shell. Third, the nanoparticles were embedded into large micelles formed by lipids. Although all approaches lead to effective negative contrast enhancement, we observed significant differences concerning the magnitude of this effect. The transverse relaxivity, in particular r(2)*, is greatly higher for the micellar system compared to the polymer-coated particles using same-sized nanoparticles. We also observed an increase in transverse relaxivities with increasing particle size for the polymer-coated nanocrystals. The results are qualitatively compared with theoretical models describing the dependence of relaxivity on the size of magnetic spheres. PB - Amer Chemical Soc, Washington T2 - Nano Letters T1 - Size and surface effects on the MRI relaxivity of manganese ferrite nanoparticle contrast agents EP - 2427 IS - 8 SP - 2422 VL - 7 DO - 10.1021/nl071099b ER -
@article{ author = "Tromsdorf, Ulrich I. and Bigall, Nadja C. and Kaul, Michael G. and Bruns, Oliver T. and Nikolić, Marija and Mollwitz, Birgit and Sperling, Ralph A. and Reimer, Rudolph and Hohenberg, Heinz and Parak, Wolfgang J. and Forster, Stephan and Beisiegel, Ulrike and Adam, Gerhard and Weller, Horst", year = "2007", abstract = "Superparamagnetic MnFe2O4 nanocrystals of different sizes were synthesized in high-boiling ether solvent and transferred into water using three different approaches. First, we applied a ligand exchange in order to form a water soluble polymer shell. Second, the particles were embedded into an amphiphilic polymer shell. Third, the nanoparticles were embedded into large micelles formed by lipids. Although all approaches lead to effective negative contrast enhancement, we observed significant differences concerning the magnitude of this effect. The transverse relaxivity, in particular r(2)*, is greatly higher for the micellar system compared to the polymer-coated particles using same-sized nanoparticles. We also observed an increase in transverse relaxivities with increasing particle size for the polymer-coated nanocrystals. The results are qualitatively compared with theoretical models describing the dependence of relaxivity on the size of magnetic spheres.", publisher = "Amer Chemical Soc, Washington", journal = "Nano Letters", title = "Size and surface effects on the MRI relaxivity of manganese ferrite nanoparticle contrast agents", pages = "2427-2422", number = "8", volume = "7", doi = "10.1021/nl071099b" }
Tromsdorf, U. I., Bigall, N. C., Kaul, M. G., Bruns, O. T., Nikolić, M., Mollwitz, B., Sperling, R. A., Reimer, R., Hohenberg, H., Parak, W. J., Forster, S., Beisiegel, U., Adam, G.,& Weller, H.. (2007). Size and surface effects on the MRI relaxivity of manganese ferrite nanoparticle contrast agents. in Nano Letters Amer Chemical Soc, Washington., 7(8), 2422-2427. https://doi.org/10.1021/nl071099b
Tromsdorf UI, Bigall NC, Kaul MG, Bruns OT, Nikolić M, Mollwitz B, Sperling RA, Reimer R, Hohenberg H, Parak WJ, Forster S, Beisiegel U, Adam G, Weller H. Size and surface effects on the MRI relaxivity of manganese ferrite nanoparticle contrast agents. in Nano Letters. 2007;7(8):2422-2427. doi:10.1021/nl071099b .
Tromsdorf, Ulrich I., Bigall, Nadja C., Kaul, Michael G., Bruns, Oliver T., Nikolić, Marija, Mollwitz, Birgit, Sperling, Ralph A., Reimer, Rudolph, Hohenberg, Heinz, Parak, Wolfgang J., Forster, Stephan, Beisiegel, Ulrike, Adam, Gerhard, Weller, Horst, "Size and surface effects on the MRI relaxivity of manganese ferrite nanoparticle contrast agents" in Nano Letters, 7, no. 8 (2007):2422-2427, https://doi.org/10.1021/nl071099b . .