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Antimikrobna aktivnost etarskog ulja i različitih frakcija Juniperus communis L. i poređenje sa nekim komercijalnim antibioticima

dc.creatorGlišić, Sandra
dc.creatorMilojević, Svetomir
dc.creatorDimitrijević, Suzana
dc.creatorOrlović, Aleksandar
dc.creatorSkala, Dejan
dc.date.accessioned2021-03-10T10:50:11Z
dc.date.available2021-03-10T10:50:11Z
dc.date.issued2007
dc.identifier.issn0352-5139
dc.identifier.urihttp://TechnoRep.tmf.bg.ac.rs/handle/123456789/1198
dc.description.abstractThe essential oil of common juniper (Juniperus communis L., from the southern part of Serbia) and its fractions of different composition, as well as commercial antibiotics were used for testing their antimicrobial activity against bacteria, yeast and fungi. The essential oil was produced by hydro-distillation in a pilot plant (130 dm3) and then fractionated by distillation over a column, with 36 theoretical stages, under vacuum (26-66 mbar). The essential oil was also fractionated using pure CO2 or CO2 and methanol as co-solvent under supercritical conditions. The native oil showed weak antimicrobial activity, while the fractions with a high content of α-pinene, and mixture of α-pinene and sabinene showed the highest antimicrobial activity, especially against fungi. In comparison to the commercial antibiotics, the oil fractions showed more extensive spectra of antimicrobial activity, as well as wider inhibition zones. .en
dc.description.abstractEtarsko ulje ploda kleke (Juniperus communis L. iz južnog dela Srbije) dobijeno je hidrodestilacijom u pilot postrojenju (130 dm3) a zatim frakcionisano u destilacionoj koloni, sa 36 teoretskih podova, pod vakuumom (26-66 mbar). Etarsko ulje je takođe frakcionisano korišćenjem čistog CO2 i smeše CO2 i metanola kao kosolventa pod natkritičnim uslovima. Devet različitih uzoraka (etarsko ulje i njegove frakcije različitih sastava) kao i komercijalni antibiotici korišćeni su u testiranju antimikrobne aktivnosti i inhibitornog uticaja na razvoj nekih bakterija, kvasaca i gljivica. Etarsko ulje kleke je pokazalo slabu antimikrobnu aktivnost na svim sojevima a frakcije sa čistim α-pinenom i smešom α-pinena i sabinena naročito na rast gljivica. U poređenju sa komercijalnim antibioticima frakcije etarskog ulja kleke pokazuju širok spektar delovanja kao i veće zone inhibicije. .sr
dc.publisherSerbian Chemical Society, Belgrade
dc.rightsopenAccess
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/
dc.sourceJournal of the Serbian Chemical Society
dc.subjectJuniperus communis L.en
dc.subjectessential oilen
dc.subjectdistillationen
dc.subjectsupercritical fractionationen
dc.subjectantimicrobial activityen
dc.subjectantibioticsen
dc.titleAntimicrobial activity of the essential oil and different fractions of Juniperus communis L. and a comparison with some commercial antibioticsen
dc.titleAntimikrobna aktivnost etarskog ulja i različitih frakcija Juniperus communis L. i poređenje sa nekim komercijalnim antibioticimasr
dc.typearticle
dc.rights.licenseBY-NC-ND
dc.citation.epage320
dc.citation.issue4
dc.citation.other72(4): 311-320
dc.citation.rankM23
dc.citation.spage311
dc.citation.volume72
dc.identifier.fulltexthttp://TechnoRep.tmf.bg.ac.rs/bitstream/id/11414/0352-51390704311G.pdf
dc.identifier.rcubhttps://hdl.handle.net/21.15107/rcub_technorep_1198
dc.identifier.scopus2-s2.0-34249790566
dc.identifier.wos000247047000001
dc.type.versionpublishedVersion


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