Chromatographic behavior and lipophilicity of n-(4-phenylsubstituted)-2,3-diphenylpropanamides
Апстракт
Retention behavior of some N-(4-phenylsubstituted)-2,3-diphenylpropanamides was investigated on reversed phase thin layer chromatography (RP-C18). Retention constants of investigated compounds were determined in the following solvent systems: water-ethanol, watern-propanol and water-i-propanol. Linear relationships were obtained between retention, RM and volume fraction of organic solvent, ϕ. As a measure of lipophilicity of tested propanamides, Hansch`s lipophilicity parameter, π, were calculated. Chromatography retention constants RM0 were correlated with Hansch`s lipophilicity parameter, and good linear relationships were obtained. These results confirm, that retention constants, (RM0 ), determined in reversed phase thin-layer chromatography (RP-TCL) can be used, as criteria of lipophilicity.
Кључне речи:
Chromatography / Compound / StructureИзвор:
Journal of Engineering & Processing Management, 2011, 3, 1, 7-15Издавач:
- University of East Sarajevo, Faculty of Technology
Финансирање / пројекти:
- Проучавање синтезе, структуре и активности органских једињења природног и синтетског порекла (RS-MESTD-Basic Research (BR or ON)-172013)
Институција/група
Tehnološko-metalurški fakultetTY - JOUR AU - Vaštag, Đenđi AU - Perišić-Janjić, Nada AU - Apostolov, Suzana AU - Petrović, Slobodan PY - 2011 UR - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/1764 AB - Retention behavior of some N-(4-phenylsubstituted)-2,3-diphenylpropanamides was investigated on reversed phase thin layer chromatography (RP-C18). Retention constants of investigated compounds were determined in the following solvent systems: water-ethanol, watern-propanol and water-i-propanol. Linear relationships were obtained between retention, RM and volume fraction of organic solvent, ϕ. As a measure of lipophilicity of tested propanamides, Hansch`s lipophilicity parameter, π, were calculated. Chromatography retention constants RM0 were correlated with Hansch`s lipophilicity parameter, and good linear relationships were obtained. These results confirm, that retention constants, (RM0 ), determined in reversed phase thin-layer chromatography (RP-TCL) can be used, as criteria of lipophilicity. PB - University of East Sarajevo, Faculty of Technology T2 - Journal of Engineering & Processing Management T1 - Chromatographic behavior and lipophilicity of n-(4-phenylsubstituted)-2,3-diphenylpropanamides EP - 15 IS - 1 SP - 7 VL - 3 UR - https://hdl.handle.net/21.15107/rcub_technorep_1764 ER -
@article{ author = "Vaštag, Đenđi and Perišić-Janjić, Nada and Apostolov, Suzana and Petrović, Slobodan", year = "2011", abstract = "Retention behavior of some N-(4-phenylsubstituted)-2,3-diphenylpropanamides was investigated on reversed phase thin layer chromatography (RP-C18). Retention constants of investigated compounds were determined in the following solvent systems: water-ethanol, watern-propanol and water-i-propanol. Linear relationships were obtained between retention, RM and volume fraction of organic solvent, ϕ. As a measure of lipophilicity of tested propanamides, Hansch`s lipophilicity parameter, π, were calculated. Chromatography retention constants RM0 were correlated with Hansch`s lipophilicity parameter, and good linear relationships were obtained. These results confirm, that retention constants, (RM0 ), determined in reversed phase thin-layer chromatography (RP-TCL) can be used, as criteria of lipophilicity.", publisher = "University of East Sarajevo, Faculty of Technology", journal = "Journal of Engineering & Processing Management", title = "Chromatographic behavior and lipophilicity of n-(4-phenylsubstituted)-2,3-diphenylpropanamides", pages = "15-7", number = "1", volume = "3", url = "https://hdl.handle.net/21.15107/rcub_technorep_1764" }
Vaštag, Đ., Perišić-Janjić, N., Apostolov, S.,& Petrović, S.. (2011). Chromatographic behavior and lipophilicity of n-(4-phenylsubstituted)-2,3-diphenylpropanamides. in Journal of Engineering & Processing Management University of East Sarajevo, Faculty of Technology., 3(1), 7-15. https://hdl.handle.net/21.15107/rcub_technorep_1764
Vaštag Đ, Perišić-Janjić N, Apostolov S, Petrović S. Chromatographic behavior and lipophilicity of n-(4-phenylsubstituted)-2,3-diphenylpropanamides. in Journal of Engineering & Processing Management. 2011;3(1):7-15. https://hdl.handle.net/21.15107/rcub_technorep_1764 .
Vaštag, Đenđi, Perišić-Janjić, Nada, Apostolov, Suzana, Petrović, Slobodan, "Chromatographic behavior and lipophilicity of n-(4-phenylsubstituted)-2,3-diphenylpropanamides" in Journal of Engineering & Processing Management, 3, no. 1 (2011):7-15, https://hdl.handle.net/21.15107/rcub_technorep_1764 .