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Swelling, Mechanical and Antimicrobial Studies of Ag/P(HEMA/IA)/PVP Semi-IPN Hybrid Hydrogels

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2011
1944.pdf (612.3Kb)
Authors
Jovašević, Jovana S.
Dimitrijević, Suzana
Filipović, Jovanka M.
Tomić, Simonida
Mićić, Maja M.
Suljovrujić, Edin H.
Conference object (Published version)
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Abstract
A simple and fast approach to the design and production of new hybrid polymeric biomaterials with silver particles is presented in this work. Silver/semi-interpenetrating network hybrid hydrogels (Ag/semi-IPNHHs) were prepared through an optimized solution crosslinking copolymerization of 2-hydroxyethyl methacrylate (HEMA) and itaconic acid (IA), in the presence of PVP, a silver salt and a reducing "green" agent (Ag/P(HEMA/IA)/PVP). PVP was chosen due to its protective, reduction, and nucleation properties in the production of metal particles. The structure of the Ag/semi-IPNHH was characterized by Fourier transform infrared spectroscopy (FTIR). The presence of silver and PVP in the network was confirmed by FTIR spectra. The results obtained by dynamic mechanical analysis (DMA) showed good mechanical properties for all samples. The swelling studies of Ag/P(HEMA/IA)/PVP were conducted in the temperature range of 25-55 degrees C, in the buffer of pH 7.40. The Ag/semi-IPNHH showed tempera...ture-sensitive swelling properties, with the lower critical solution temperature (LCST) values in the physiologically interesting interval. The antimicrobial activity of the samples was tested using E. coli, S. aureus and C. albicans pathogens. It was concluded that the antimicrobial potential depends on the hydrogel's composition and the type of microbes

Source:
Acta Physica Polonica A, 2011, 120, 2, 279-283
Publisher:
  • Polish Acad Sciences Inst Physics, Warsaw
Funding / projects:
  • Chemical and structural designing of nanomaterials for application in medicine and tissue engineering (RS-172026)
  • Synthesis and characterization of novel functional polymers and polymeric nanocomposites (RS-172062)

DOI: 10.12693/APhysPolA.120.279

ISSN: 0587-4246

WoS: 000291836900016

Scopus: 2-s2.0-79960124839
[ Google Scholar ]
10
11
URI
http://TechnoRep.tmf.bg.ac.rs/handle/123456789/1947
Collections
  • Radovi istraživača / Researchers’ publications (TMF)
Institution/Community
Tehnološko-metalurški fakultet
TY  - CONF
AU  - Jovašević, Jovana S.
AU  - Dimitrijević, Suzana
AU  - Filipović, Jovanka M.
AU  - Tomić, Simonida
AU  - Mićić, Maja M.
AU  - Suljovrujić, Edin H.
PY  - 2011
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/1947
AB  - A simple and fast approach to the design and production of new hybrid polymeric biomaterials with silver particles is presented in this work. Silver/semi-interpenetrating network hybrid hydrogels (Ag/semi-IPNHHs) were prepared through an optimized solution crosslinking copolymerization of 2-hydroxyethyl methacrylate (HEMA) and itaconic acid (IA), in the presence of PVP, a silver salt and a reducing "green" agent (Ag/P(HEMA/IA)/PVP). PVP was chosen due to its protective, reduction, and nucleation properties in the production of metal particles. The structure of the Ag/semi-IPNHH was characterized by Fourier transform infrared spectroscopy (FTIR). The presence of silver and PVP in the network was confirmed by FTIR spectra. The results obtained by dynamic mechanical analysis (DMA) showed good mechanical properties for all samples. The swelling studies of Ag/P(HEMA/IA)/PVP were conducted in the temperature range of 25-55 degrees C, in the buffer of pH 7.40. The Ag/semi-IPNHH showed temperature-sensitive swelling properties, with the lower critical solution temperature (LCST) values in the physiologically interesting interval. The antimicrobial activity of the samples was tested using E. coli, S. aureus and C. albicans pathogens. It was concluded that the antimicrobial potential depends on the hydrogel's composition and the type of microbes
PB  - Polish Acad Sciences Inst Physics, Warsaw
C3  - Acta Physica Polonica A
T1  - Swelling, Mechanical and Antimicrobial Studies of Ag/P(HEMA/IA)/PVP Semi-IPN Hybrid Hydrogels
EP  - 283
IS  - 2
SP  - 279
VL  - 120
DO  - 10.12693/APhysPolA.120.279
UR  - conv_3605
ER  - 
@conference{
author = "Jovašević, Jovana S. and Dimitrijević, Suzana and Filipović, Jovanka M. and Tomić, Simonida and Mićić, Maja M. and Suljovrujić, Edin H.",
year = "2011",
abstract = "A simple and fast approach to the design and production of new hybrid polymeric biomaterials with silver particles is presented in this work. Silver/semi-interpenetrating network hybrid hydrogels (Ag/semi-IPNHHs) were prepared through an optimized solution crosslinking copolymerization of 2-hydroxyethyl methacrylate (HEMA) and itaconic acid (IA), in the presence of PVP, a silver salt and a reducing "green" agent (Ag/P(HEMA/IA)/PVP). PVP was chosen due to its protective, reduction, and nucleation properties in the production of metal particles. The structure of the Ag/semi-IPNHH was characterized by Fourier transform infrared spectroscopy (FTIR). The presence of silver and PVP in the network was confirmed by FTIR spectra. The results obtained by dynamic mechanical analysis (DMA) showed good mechanical properties for all samples. The swelling studies of Ag/P(HEMA/IA)/PVP were conducted in the temperature range of 25-55 degrees C, in the buffer of pH 7.40. The Ag/semi-IPNHH showed temperature-sensitive swelling properties, with the lower critical solution temperature (LCST) values in the physiologically interesting interval. The antimicrobial activity of the samples was tested using E. coli, S. aureus and C. albicans pathogens. It was concluded that the antimicrobial potential depends on the hydrogel's composition and the type of microbes",
publisher = "Polish Acad Sciences Inst Physics, Warsaw",
journal = "Acta Physica Polonica A",
title = "Swelling, Mechanical and Antimicrobial Studies of Ag/P(HEMA/IA)/PVP Semi-IPN Hybrid Hydrogels",
pages = "283-279",
number = "2",
volume = "120",
doi = "10.12693/APhysPolA.120.279",
url = "conv_3605"
}
Jovašević, J. S., Dimitrijević, S., Filipović, J. M., Tomić, S., Mićić, M. M.,& Suljovrujić, E. H.. (2011). Swelling, Mechanical and Antimicrobial Studies of Ag/P(HEMA/IA)/PVP Semi-IPN Hybrid Hydrogels. in Acta Physica Polonica A
Polish Acad Sciences Inst Physics, Warsaw., 120(2), 279-283.
https://doi.org/10.12693/APhysPolA.120.279
conv_3605
Jovašević JS, Dimitrijević S, Filipović JM, Tomić S, Mićić MM, Suljovrujić EH. Swelling, Mechanical and Antimicrobial Studies of Ag/P(HEMA/IA)/PVP Semi-IPN Hybrid Hydrogels. in Acta Physica Polonica A. 2011;120(2):279-283.
doi:10.12693/APhysPolA.120.279
conv_3605 .
Jovašević, Jovana S., Dimitrijević, Suzana, Filipović, Jovanka M., Tomić, Simonida, Mićić, Maja M., Suljovrujić, Edin H., "Swelling, Mechanical and Antimicrobial Studies of Ag/P(HEMA/IA)/PVP Semi-IPN Hybrid Hydrogels" in Acta Physica Polonica A, 120, no. 2 (2011):279-283,
https://doi.org/10.12693/APhysPolA.120.279 .,
conv_3605 .

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