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dc.creatorStoiljković, Zora Ž.
dc.creatorJovanović, Vladislava M.
dc.creatorMijin, Dušan
dc.creatorNikolić, V.
dc.creatorNikolić, Ljubiša B.
dc.creatorPetrović, Slobodan
dc.creatorAvramov-Ivić, Milka
dc.date.accessioned2021-03-10T11:58:35Z
dc.date.available2021-03-10T11:58:35Z
dc.date.issued2013
dc.identifier.issn1452-3981
dc.identifier.urihttp://TechnoRep.tmf.bg.ac.rs/handle/123456789/2259
dc.description.abstractThe electrochemical behavior of inclusion complexes of nifedipine (Nif) and amlodipine (Aml), a long-acting calcium channel blockers dihydropyridine (DHP) class, with beta-cyclodextrin (beta CD) and (2-hydroxypropyl)-beta-cyclodextrin (HP beta CD), is examined using cyclic and square wave voltammetry in 0.05 M NaHCO3 and phosphate buffer (pH=11) on a gold electrode. The voltammograms show a single irreversible anodic wave with the current controlled by adsorption. It was found that phosphate buffer favorites the electrochemical activity of both complexes of Nif with the linear dependency of the oxidative currents on their concentrations. In phosphate buffer, only HP beta CD-Aml complex showed linear dependency of the oxidative currents on the concentration. In 0.05 M NaHCO3 as electrolyte only HP beta CD-Nif exhibited apparent activity. The initial potential of the anodic reaction as well as the value of the potential for anodic currents maximum of all the examined complexes in both electrolytes were shifted to the positive direction compared to their standards. In addition, the value of anodic currents decreased.en
dc.publisherElectrochemical Science Group, Beograd
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172013/RS//
dc.rightsrestrictedAccess
dc.sourceInternational Journal of Electrochemical Science
dc.subjectcyclodextrin complexesen
dc.subjectelectrochemical determinationen
dc.subjectgold electrodeen
dc.subjectcyclic voltammetryen
dc.subjectsquare wave voltammetryen
dc.titleThe Electrochemical Investigation of Inclusion Complexes of Nifedipine and Amlodipine with beta-Cyclodextrin and (2-Hydroxypropyl)-beta-Cyclodextrinen
dc.typearticle
dc.rights.licenseARR
dc.citation.epage9557
dc.citation.issue7
dc.citation.other8(7): 9543-9557
dc.citation.rankM22
dc.citation.spage9543
dc.citation.volume8
dc.identifier.pmid
dc.identifier.rcubhttps://hdl.handle.net/21.15107/rcub_technorep_2259
dc.identifier.scopus2-s2.0-84881578068
dc.identifier.wos000323547600055
dc.type.versionpublishedVersion


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Приказ основних података о документу