Biomedical fibrous materials PP/viscose with programmed properties as transdermal systems

Abstract

The subject of this paper is the behaviour of the biomedical fibrous materials in the form of transdermal sistem for wound dressing, consisting of a nonwoven textile base which contains polypropylene (PP) / viscose, a polymer carrier and an antimicrobial active substances. The polymer carrier of the antimicrobial active substance is the polysaccharide D-glucosamine (chitosan), and the active antimicrobial substance is gentamicin sulphate, sodium fusidate, as well as autochthone essential oils (Abies Sibirica) and (Rosmarinus Officinalis) nature antimicrobial preparations. Bioactivity of obtained antimicrobial fibrous materials was tested in vitro on different groups of gram-positive and gram-negative bacteria: Staphilococcus aureus, Escherichia coli, Candida albicans, Pseudomonas aeruginosa. Especially good results regarding the observed bacteria are shown biomedical fibrous material with gentamicin sulfate. This antimicrobial material could be the ideal dressing for protection of the wound from external contaminations.

U ovom radu je proučeno ponašanje biomedicinskog vlaknastog materijala, u obliku transdermalnog sistema, koji se sastoji od netkane tekstilne podloge sirovinskog sastava polipropilen viskoza, polimer nosača i antimikrobne aktivne supstance. Polimer nosač antimikrobne aktivne supstance je polisaharid D-glukozamin (hitozan), a aktivne supstance gentamicinsulfat, natrijumfusidat i autohtona esencijalna ulja sibirske jele (Abies Sibirica) i ruzmarina (Rosmarinus Officinalis), prirodna antimikrobna sredstva. Bioaktivnost dobijenih antimikrobnih vlaknastih materijala testirana je in vitro. na različite vrste gram-pozitivnih i gram-negativnih mikroorganizama: Staphilococcus aureus, Escherichia coli, Candida albicans, Pseudomonas aeruginosa. Visoku efikasnost pokazao je biomedicinski vlaknasti materijal koji sadrži gentamicinsulfat. Ovi antimikrobni materijali mogu biti idealni flasteri za zaštitu rana od spoljašnje kontaminacije.