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dc.creatorZvicer, Jovana
dc.creatorSamardžić, M.
dc.creatorMišković-Stanković, Vesna
dc.creatorObradović, Bojana
dc.date.accessioned2021-03-10T12:38:01Z
dc.date.available2021-03-10T12:38:01Z
dc.date.issued2015
dc.identifier.urihttp://TechnoRep.tmf.bg.ac.rs/handle/123456789/2880
dc.description.abstractAlginate nanocomposite hydrogels with incorporated electrochemically synthesized silver nanoparticles were investigated regarding cytotoxicity in vitro. Direct contact test of Ag/alginate discs was applied in 2D monolayer cultures of bovine calf chondrocytes while a 3D culture of bovine articular cartilage explants pressed by the discs was established in a biomimetic bioreactor with dynamic compression in the physiological regime (10 % strain, 0.84 Hz frequency, 1 h on / 1 h off). Moderate cytotoxicity was observed in 2D cell cultures as opposed to findings in 3D explant cultures, which were not affected by the Ag/alginate discs despite the compression.en
dc.publisher15th IEEE International Conference on Bioinformatics and Bioengineering, BIBE 2015
dc.rightsrestrictedAccess
dc.source2015 IEEE 15th International Conference on Bioinformatics and Bioengineering, BIBE 2015
dc.titleCytotoxicity studies of Ag/alginate nanocomposite hydrogels in 2D and 3D culturesen
dc.typearticle
dc.rights.licenseARR
dc.identifier.doi10.1109/BIBE.2015.7367664
dc.identifier.pmid
dc.identifier.rcubconv_6497
dc.identifier.scopus2-s2.0-84962875856
dc.type.versionpublishedVersion


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