Smart hydrogels for pharmaceutical applications
Abstract
The latest development in the field of smart hydrogels application as drugs carriers is shown in this chapter. Hydrogels are three-dimensional polymer network consisting of at least one hydrophilic monomer. They are insoluble in water, but in the excess presence of water or physiological fluids, swell to the equilibrium state. The amount of absorbed water depends on the chemical composition and the crosslinking degree of 3D hydrogel network and reaches over 1000% of the xerogel weight. Stimuli-responsive hydrogels exhibit significant change of their properties (swelling, color, transparency, conductivity, shape) due to small changes in the external environment conditions (pH, ionic strength, temperature, light wavelength, magnetic or electric fields, ultrasound, or a combination thereof). This smart hydrogels, with different physical and chemical properties, chemical structure and technology of obtaining, show great potential for application in the pharmaceutical industry. The applicat...ion of smart hydrogels is very promising and at the beginning of the development and exploitation.
Source:
Novel Approaches for Drug Delivery, 2016, 278-310
DOI: 10.4018/978-1-5225-0751-2.ch0011
ISBN: 978-152250752-9
PubMed:
Scopus: 2-s2.0-85014014130
Institution/Community
Tehnološko-metalurški fakultetTY - CHAP AU - Ilić-Stojanović, Snežana AU - Nikolić, Ljubiša B. AU - Nikolić, V.D. AU - Petrović, Slobodan PY - 2016 UR - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3162 AB - The latest development in the field of smart hydrogels application as drugs carriers is shown in this chapter. Hydrogels are three-dimensional polymer network consisting of at least one hydrophilic monomer. They are insoluble in water, but in the excess presence of water or physiological fluids, swell to the equilibrium state. The amount of absorbed water depends on the chemical composition and the crosslinking degree of 3D hydrogel network and reaches over 1000% of the xerogel weight. Stimuli-responsive hydrogels exhibit significant change of their properties (swelling, color, transparency, conductivity, shape) due to small changes in the external environment conditions (pH, ionic strength, temperature, light wavelength, magnetic or electric fields, ultrasound, or a combination thereof). This smart hydrogels, with different physical and chemical properties, chemical structure and technology of obtaining, show great potential for application in the pharmaceutical industry. The application of smart hydrogels is very promising and at the beginning of the development and exploitation. T2 - Novel Approaches for Drug Delivery T1 - Smart hydrogels for pharmaceutical applications EP - 310 SP - 278 DO - 10.4018/978-1-5225-0751-2.ch0011 ER -
@inbook{ author = "Ilić-Stojanović, Snežana and Nikolić, Ljubiša B. and Nikolić, V.D. and Petrović, Slobodan", year = "2016", abstract = "The latest development in the field of smart hydrogels application as drugs carriers is shown in this chapter. Hydrogels are three-dimensional polymer network consisting of at least one hydrophilic monomer. They are insoluble in water, but in the excess presence of water or physiological fluids, swell to the equilibrium state. The amount of absorbed water depends on the chemical composition and the crosslinking degree of 3D hydrogel network and reaches over 1000% of the xerogel weight. Stimuli-responsive hydrogels exhibit significant change of their properties (swelling, color, transparency, conductivity, shape) due to small changes in the external environment conditions (pH, ionic strength, temperature, light wavelength, magnetic or electric fields, ultrasound, or a combination thereof). This smart hydrogels, with different physical and chemical properties, chemical structure and technology of obtaining, show great potential for application in the pharmaceutical industry. The application of smart hydrogels is very promising and at the beginning of the development and exploitation.", journal = "Novel Approaches for Drug Delivery", booktitle = "Smart hydrogels for pharmaceutical applications", pages = "310-278", doi = "10.4018/978-1-5225-0751-2.ch0011" }
Ilić-Stojanović, S., Nikolić, L. B., Nikolić, V.D.,& Petrović, S.. (2016). Smart hydrogels for pharmaceutical applications. in Novel Approaches for Drug Delivery, 278-310. https://doi.org/10.4018/978-1-5225-0751-2.ch0011
Ilić-Stojanović S, Nikolić LB, Nikolić V, Petrović S. Smart hydrogels for pharmaceutical applications. in Novel Approaches for Drug Delivery. 2016;:278-310. doi:10.4018/978-1-5225-0751-2.ch0011 .
Ilić-Stojanović, Snežana, Nikolić, Ljubiša B., Nikolić, V.D., Petrović, Slobodan, "Smart hydrogels for pharmaceutical applications" in Novel Approaches for Drug Delivery (2016):278-310, https://doi.org/10.4018/978-1-5225-0751-2.ch0011 . .