One-step synthesis of NIR-responsive NaYF4:Yb,Er"Chitosane nanoparticles for biomedical application
2017
Аутори
Dinić, IvanaĐukić-Vuković, Aleksandra
Mojović, Ljiljana
Nikolić, Marko G.
Rabasović, Mihailo D.
Krmpot, Aleksandar
Milošević, Olivera
Mančić, Lidija
Конференцијски прилог (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
There is a great technological interest in synthesis of lanthanide doped upconverting nanoparticles with specific morphological characteristics and efficient luminescence response suitable for biomedical use [1]. A conventional approach for generation of such particles comprises decomposition of organometallic compoundsin an oxygen-free environment and additional ligand exchange [2,3]. The biocompatible and water soluble NaYF4:Yb,Er"Chitosane particles used in this study were synthesized through facile one-pot hydrothermal synthesis and were characterized using X-ray powder diffraction (XRPD), Fourier-transform infrared (FTIR) spectroscopy, field emission scanning and transmission electron microscopy (FESEM and TEM) and photoluminesce measurement (PL). Due to the presence of the amino groups at their surface these particles exhibit excellent hydrophilic properties and low cytotoxicity against human gingival fibroblasts (HGF), which was proven by MTT assay. Furthermore, upon 980 nm lase...r irradiation the as-prepared particles were successfully used for in-vitro visualization of the primary cell cultures of head and neck squamous carcinoma cells (HNSCC). In a NaYF4:Yb,Er phase upconversion is enabled by the sequential absorption of two or more near-infrared photons by Yb3+ and subsequent energy transfer to the long-lived metastable electron states of Er3+ which produces luminescence emission at visible spectra after relaxation.
Кључне речи:
nanoparticles / upconversion / biomedical materials / NaYF4:Yb,Er / chitosanИзвор:
Abstracts of Tutorial, Keynote, Invited Lectures, Progress Reports and Contributed Papers of the Six, 2017, 81-81Издавач:
- Belgrade : Institute of Physics Belgrade
Финансирање / пројекти:
- Материјали редуковане димензионалности за ефикасну апсорпцију светлости и конверзију енергије (RS-MESTD-Integrated and Interdisciplinary Research (IIR or III)-45020)
Институција/група
Tehnološko-metalurški fakultetTY - CONF AU - Dinić, Ivana AU - Đukić-Vuković, Aleksandra AU - Mojović, Ljiljana AU - Nikolić, Marko G. AU - Rabasović, Mihailo D. AU - Krmpot, Aleksandar AU - Milošević, Olivera AU - Mančić, Lidija PY - 2017 UR - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3486 AB - There is a great technological interest in synthesis of lanthanide doped upconverting nanoparticles with specific morphological characteristics and efficient luminescence response suitable for biomedical use [1]. A conventional approach for generation of such particles comprises decomposition of organometallic compoundsin an oxygen-free environment and additional ligand exchange [2,3]. The biocompatible and water soluble NaYF4:Yb,Er"Chitosane particles used in this study were synthesized through facile one-pot hydrothermal synthesis and were characterized using X-ray powder diffraction (XRPD), Fourier-transform infrared (FTIR) spectroscopy, field emission scanning and transmission electron microscopy (FESEM and TEM) and photoluminesce measurement (PL). Due to the presence of the amino groups at their surface these particles exhibit excellent hydrophilic properties and low cytotoxicity against human gingival fibroblasts (HGF), which was proven by MTT assay. Furthermore, upon 980 nm laser irradiation the as-prepared particles were successfully used for in-vitro visualization of the primary cell cultures of head and neck squamous carcinoma cells (HNSCC). In a NaYF4:Yb,Er phase upconversion is enabled by the sequential absorption of two or more near-infrared photons by Yb3+ and subsequent energy transfer to the long-lived metastable electron states of Er3+ which produces luminescence emission at visible spectra after relaxation. PB - Belgrade : Institute of Physics Belgrade C3 - Abstracts of Tutorial, Keynote, Invited Lectures, Progress Reports and Contributed Papers of the Six T1 - One-step synthesis of NIR-responsive NaYF4:Yb,Er"Chitosane nanoparticles for biomedical application EP - 81 SP - 81 UR - https://hdl.handle.net/21.15107/rcub_technorep_3486 ER -
@conference{ author = "Dinić, Ivana and Đukić-Vuković, Aleksandra and Mojović, Ljiljana and Nikolić, Marko G. and Rabasović, Mihailo D. and Krmpot, Aleksandar and Milošević, Olivera and Mančić, Lidija", year = "2017", abstract = "There is a great technological interest in synthesis of lanthanide doped upconverting nanoparticles with specific morphological characteristics and efficient luminescence response suitable for biomedical use [1]. A conventional approach for generation of such particles comprises decomposition of organometallic compoundsin an oxygen-free environment and additional ligand exchange [2,3]. The biocompatible and water soluble NaYF4:Yb,Er"Chitosane particles used in this study were synthesized through facile one-pot hydrothermal synthesis and were characterized using X-ray powder diffraction (XRPD), Fourier-transform infrared (FTIR) spectroscopy, field emission scanning and transmission electron microscopy (FESEM and TEM) and photoluminesce measurement (PL). Due to the presence of the amino groups at their surface these particles exhibit excellent hydrophilic properties and low cytotoxicity against human gingival fibroblasts (HGF), which was proven by MTT assay. Furthermore, upon 980 nm laser irradiation the as-prepared particles were successfully used for in-vitro visualization of the primary cell cultures of head and neck squamous carcinoma cells (HNSCC). In a NaYF4:Yb,Er phase upconversion is enabled by the sequential absorption of two or more near-infrared photons by Yb3+ and subsequent energy transfer to the long-lived metastable electron states of Er3+ which produces luminescence emission at visible spectra after relaxation.", publisher = "Belgrade : Institute of Physics Belgrade", journal = "Abstracts of Tutorial, Keynote, Invited Lectures, Progress Reports and Contributed Papers of the Six", title = "One-step synthesis of NIR-responsive NaYF4:Yb,Er"Chitosane nanoparticles for biomedical application", pages = "81-81", url = "https://hdl.handle.net/21.15107/rcub_technorep_3486" }
Dinić, I., Đukić-Vuković, A., Mojović, L., Nikolić, M. G., Rabasović, M. D., Krmpot, A., Milošević, O.,& Mančić, L.. (2017). One-step synthesis of NIR-responsive NaYF4:Yb,Er"Chitosane nanoparticles for biomedical application. in Abstracts of Tutorial, Keynote, Invited Lectures, Progress Reports and Contributed Papers of the Six Belgrade : Institute of Physics Belgrade., 81-81. https://hdl.handle.net/21.15107/rcub_technorep_3486
Dinić I, Đukić-Vuković A, Mojović L, Nikolić MG, Rabasović MD, Krmpot A, Milošević O, Mančić L. One-step synthesis of NIR-responsive NaYF4:Yb,Er"Chitosane nanoparticles for biomedical application. in Abstracts of Tutorial, Keynote, Invited Lectures, Progress Reports and Contributed Papers of the Six. 2017;:81-81. https://hdl.handle.net/21.15107/rcub_technorep_3486 .
Dinić, Ivana, Đukić-Vuković, Aleksandra, Mojović, Ljiljana, Nikolić, Marko G., Rabasović, Mihailo D., Krmpot, Aleksandar, Milošević, Olivera, Mančić, Lidija, "One-step synthesis of NIR-responsive NaYF4:Yb,Er"Chitosane nanoparticles for biomedical application" in Abstracts of Tutorial, Keynote, Invited Lectures, Progress Reports and Contributed Papers of the Six (2017):81-81, https://hdl.handle.net/21.15107/rcub_technorep_3486 .