Design of pectin-sodium alginate based films for potential healthcare application: Study of chemico-physical interactions between the components of films and assessment of their antimicrobial activity
Само за регистроване кориснике
2017
Аутори
Nešić, AleksandraOnjia, Antonije
Davidović, Slađana
Dimitrijević, Suzana
Errico, Maria Emanuela
Santagata, Gabriella
Malinconico, Mario
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
In this study, pectin based films including different amounts of sodium alginate were prepared by casting method. All the films, with and without polyglycerol as plasticizer, were crosslinked with zinc ions in order to extend their potential functionality. The development of junction points, occurring during the crosslinking process with zinc ions, induced the increasing of free volume with following changing in chemico-physical properties of films. The inclusion of alginate in pectin based formulations improved the strength of zinc ions crosslinking network, whereas the addition of polyglycerol significantly improved mechanical performance. Finally, zinc-crosslinked films evidenced antimicrobial activity against the most common exploited pathogens: Staphylococcus Aureus, Escherichia Coli and Candida Albicans. These results suggest that zinc-crosslinked based films can be exploitable as novel bio-active biomaterials for protection and disinfection of medical devices.
Кључне речи:
Pectin / Alginate / Zinc crosslinking / Antimicrobial filmsИзвор:
Carbohydrate Polymers, 2017, 157, 981-990Издавач:
- Elsevier Sci Ltd, Oxford
Финансирање / пројекти:
- Ministry of Education, University and Research of the Republic of Italy [RS13MO4]
- National Technological Cluster of Ministry of University and Research (MIUR)
- Нове технологије за мониторинг и заштиту животног окружења од штетних хемијских супстанци и радијационог оптерећења (RS-43009)
- Примена биотехнолошких метода у одрживом искоришћењу нус-производа агроиндустрије (RS-31035)
DOI: 10.1016/j.carbpol.2016.10.054
ISSN: 0144-8617
PubMed: 27988017
WoS: 000391896800111
Scopus: 2-s2.0-85005978040
Институција/група
Tehnološko-metalurški fakultetTY - JOUR AU - Nešić, Aleksandra AU - Onjia, Antonije AU - Davidović, Slađana AU - Dimitrijević, Suzana AU - Errico, Maria Emanuela AU - Santagata, Gabriella AU - Malinconico, Mario PY - 2017 UR - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3671 AB - In this study, pectin based films including different amounts of sodium alginate were prepared by casting method. All the films, with and without polyglycerol as plasticizer, were crosslinked with zinc ions in order to extend their potential functionality. The development of junction points, occurring during the crosslinking process with zinc ions, induced the increasing of free volume with following changing in chemico-physical properties of films. The inclusion of alginate in pectin based formulations improved the strength of zinc ions crosslinking network, whereas the addition of polyglycerol significantly improved mechanical performance. Finally, zinc-crosslinked films evidenced antimicrobial activity against the most common exploited pathogens: Staphylococcus Aureus, Escherichia Coli and Candida Albicans. These results suggest that zinc-crosslinked based films can be exploitable as novel bio-active biomaterials for protection and disinfection of medical devices. PB - Elsevier Sci Ltd, Oxford T2 - Carbohydrate Polymers T1 - Design of pectin-sodium alginate based films for potential healthcare application: Study of chemico-physical interactions between the components of films and assessment of their antimicrobial activity EP - 990 SP - 981 VL - 157 DO - 10.1016/j.carbpol.2016.10.054 ER -
@article{ author = "Nešić, Aleksandra and Onjia, Antonije and Davidović, Slađana and Dimitrijević, Suzana and Errico, Maria Emanuela and Santagata, Gabriella and Malinconico, Mario", year = "2017", abstract = "In this study, pectin based films including different amounts of sodium alginate were prepared by casting method. All the films, with and without polyglycerol as plasticizer, were crosslinked with zinc ions in order to extend their potential functionality. The development of junction points, occurring during the crosslinking process with zinc ions, induced the increasing of free volume with following changing in chemico-physical properties of films. The inclusion of alginate in pectin based formulations improved the strength of zinc ions crosslinking network, whereas the addition of polyglycerol significantly improved mechanical performance. Finally, zinc-crosslinked films evidenced antimicrobial activity against the most common exploited pathogens: Staphylococcus Aureus, Escherichia Coli and Candida Albicans. These results suggest that zinc-crosslinked based films can be exploitable as novel bio-active biomaterials for protection and disinfection of medical devices.", publisher = "Elsevier Sci Ltd, Oxford", journal = "Carbohydrate Polymers", title = "Design of pectin-sodium alginate based films for potential healthcare application: Study of chemico-physical interactions between the components of films and assessment of their antimicrobial activity", pages = "990-981", volume = "157", doi = "10.1016/j.carbpol.2016.10.054" }
Nešić, A., Onjia, A., Davidović, S., Dimitrijević, S., Errico, M. E., Santagata, G.,& Malinconico, M.. (2017). Design of pectin-sodium alginate based films for potential healthcare application: Study of chemico-physical interactions between the components of films and assessment of their antimicrobial activity. in Carbohydrate Polymers Elsevier Sci Ltd, Oxford., 157, 981-990. https://doi.org/10.1016/j.carbpol.2016.10.054
Nešić A, Onjia A, Davidović S, Dimitrijević S, Errico ME, Santagata G, Malinconico M. Design of pectin-sodium alginate based films for potential healthcare application: Study of chemico-physical interactions between the components of films and assessment of their antimicrobial activity. in Carbohydrate Polymers. 2017;157:981-990. doi:10.1016/j.carbpol.2016.10.054 .
Nešić, Aleksandra, Onjia, Antonije, Davidović, Slađana, Dimitrijević, Suzana, Errico, Maria Emanuela, Santagata, Gabriella, Malinconico, Mario, "Design of pectin-sodium alginate based films for potential healthcare application: Study of chemico-physical interactions between the components of films and assessment of their antimicrobial activity" in Carbohydrate Polymers, 157 (2017):981-990, https://doi.org/10.1016/j.carbpol.2016.10.054 . .